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The map label for this gene is trpG_1 [H]

Identifier: 15602448

GI number: 15602448

Start: 671652

End: 672239

Strand: Reverse

Name: trpG_1 [H]

Synonym: PM0583

Alternate gene names: 15602448

Gene position: 672239-671652 (Counterclockwise)

Preceding gene: 15602449

Following gene: 15602446

Centisome position: 29.78

GC content: 40.31

Gene sequence:

>588_bases
ATGGCAAAGATTGTATTTTTAGATAATTTTGACTCCTTTACCTATAACTTAGTGGATCAGTTGCGTTGTTTAGGACATCA
AGTCCACATCTATCGTAATGATTGTGATCTCGATGTATTAGAACAGGTTACACTTGCCCACCCCAATACGATTCTAGCGC
TTTCACCTGGTCCGAGTACACCGCAACAAGCGGGTAATATGTTACCCCTGATTCAGCGTTTAAAACAAAAGGTTAGAATG
ATTGGCATTTGTTTAGGTCATCAAGCGATTGTTGAAGCATTTGGTGGTAAAGTAATCCATGCAGGCGAAGTCTTACATGG
CAAAGTGTCAAACATTACACACGATCAGCAAATGATGTTTGCACACTTACCAAATCCAATGCCCGTCGCACGATACCACT
CCTTAATGGGCGTTGATTTATCTGACGAATTTATTGTCAACGCAACCTACCATGACATTATCATGGCTATTCGACATAAA
CATTTGCCGATTTGTAGTTTTCAATTTCATCCAGAAAGCATCTTAACAGTGCAAGGTTCACAGTTATTAGCGCAGTCTAT
TGAATGGCTGTTGGCGCATGAAATCTGA

Upstream 100 bases:

>100_bases
CCGCAAAAAGAAGCCGATGAAACACGACACAAAGCACAAGCCGTGATTAACGCGATTGTTCAAACTCACCAAACACCTCG
TCAAGCATAAGGACAGCAGT

Downstream 100 bases:

>100_bases
ACACCTTCGAGCACACTTAGGTGGGTGATGAAAAGATAAGTAACCCTGTCACATAAATACTGATTGCCATCAGACTGATA
ATAGTTCCACAGGCAATTCG

Product: anthranilate synthase component II

Products: NA

Alternate protein names: Glutamine amido-transferase [H]

Number of amino acids: Translated: 195; Mature: 194

Protein sequence:

>195_residues
MAKIVFLDNFDSFTYNLVDQLRCLGHQVHIYRNDCDLDVLEQVTLAHPNTILALSPGPSTPQQAGNMLPLIQRLKQKVRM
IGICLGHQAIVEAFGGKVIHAGEVLHGKVSNITHDQQMMFAHLPNPMPVARYHSLMGVDLSDEFIVNATYHDIIMAIRHK
HLPICSFQFHPESILTVQGSQLLAQSIEWLLAHEI

Sequences:

>Translated_195_residues
MAKIVFLDNFDSFTYNLVDQLRCLGHQVHIYRNDCDLDVLEQVTLAHPNTILALSPGPSTPQQAGNMLPLIQRLKQKVRM
IGICLGHQAIVEAFGGKVIHAGEVLHGKVSNITHDQQMMFAHLPNPMPVARYHSLMGVDLSDEFIVNATYHDIIMAIRHK
HLPICSFQFHPESILTVQGSQLLAQSIEWLLAHEI
>Mature_194_residues
AKIVFLDNFDSFTYNLVDQLRCLGHQVHIYRNDCDLDVLEQVTLAHPNTILALSPGPSTPQQAGNMLPLIQRLKQKVRMI
GICLGHQAIVEAFGGKVIHAGEVLHGKVSNITHDQQMMFAHLPNPMPVARYHSLMGVDLSDEFIVNATYHDIIMAIRHKH
LPICSFQFHPESILTVQGSQLLAQSIEWLLAHEI

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=189, Percent_Identity=56.0846560846561, Blast_Score=222, Evalue=1e-59,
Organism=Escherichia coli, GI1789760, Length=189, Percent_Identity=44.973544973545, Blast_Score=146, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6322638, Length=180, Percent_Identity=40, Blast_Score=139, Evalue=3e-34,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 21900; Mature: 21769

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKIVFLDNFDSFTYNLVDQLRCLGHQVHIYRNDCDLDVLEQVTLAHPNTILALSPGPST
CEEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCEEEEECCCCCC
PQQAGNMLPLIQRLKQKVRMIGICLGHQAIVEAFGGKVIHAGEVLHGKVSNITHDQQMMF
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHCCCCHHHHHH
AHLPNPMPVARYHSLMGVDLSDEFIVNATYHDIIMAIRHKHLPICSFQFHPESILTVQGS
HHCCCCCCHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHCCCCEEEEEECCCEEEEECCH
QLLAQSIEWLLAHEI
HHHHHHHHHHHHCCC
>Mature Secondary Structure 
AKIVFLDNFDSFTYNLVDQLRCLGHQVHIYRNDCDLDVLEQVTLAHPNTILALSPGPST
EEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCEEEEECCCCCC
PQQAGNMLPLIQRLKQKVRMIGICLGHQAIVEAFGGKVIHAGEVLHGKVSNITHDQQMMF
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHCCCCHHHHHH
AHLPNPMPVARYHSLMGVDLSDEFIVNATYHDIIMAIRHKHLPICSFQFHPESILTVQGS
HHCCCCCCHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHCCCCEEEEEECCCEEEEECCH
QLLAQSIEWLLAHEI
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]