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The map label for this gene is glnS

Identifier: 15602393

GI number: 15602393

Start: 603945

End: 605624

Strand: Direct

Name: glnS

Synonym: PM0528

Alternate gene names: 15602393

Gene position: 603945-605624 (Clockwise)

Preceding gene: 15602388

Following gene: 15602394

Centisome position: 26.75

GC content: 41.01

Gene sequence:

>1680_bases
ATGAGTCATCCAGTTGAAAATGTTGTCGCAGCTGAAAATACAGAAAAACGTCCCACCAATTTTATTCGTCAAATCATTGA
TGAAGATTTAGCATCCGGCAAACATACCGGTGTCCAAACACGTTTTCCACCTGAACCCAATGGCTATTTGCATATTGGTC
ATGCCAAATCAATTTGCTTAAATTTTGGTATCGCTGAAGATTATCAAGGGTTGTGTAATTTACGTTTCGATGATACGAAT
CCCGTCAAAGAAGATGTGGAATATGTGGATTCGATTAAACAAGATGTAGAATGGTTAGGTTTCAAGTGGGAAGGAGAGCC
TCGTTATGCCTCCGACTATTTTGATCAACTCTATGGCTATGCGATTGAGTTAATCGAAAAAGGGTTAGCTTATGTGGATG
AACTTTCGCCAGAAGAAATGCGTGAATACCGTGGTACGTTAACGGAACCGGGTAAAAATAGCCCTTATCGTGATCGTTCT
ATTGAAGAAAACCTCGCGTTATTTGAGAAAATGAAGAACGGAGAAATTGCAGAAGGCAAAGCCTGTTTACGTGCGAAAAT
TGATATGGCGTCTCCGTTTATTGTCATGCGCGATCCAGTAATTTATCGGATTAAATTTGCGACCCATCACCAAACAGGTG
ATAAATGGTGCATTTACCCAATGTATGATTTTACTCATTGTATCTCTGATGCCATTGAGCGCATTACTCATTCGCTTTGT
ACATTGGAATTCCAAGATAATCGTCGTTTGTATGACTGGGTATTAGAAAATATTTCGATTGCGCGTCCATTGCCGCACCA
GTATGAGTTTTCACGTTTAAATTTAGAATCGACCCTCACTTCTAAACGTAAATTATTACAACTGGTGAATGAAGGTATTG
TCGATGGCTGGAATGACCCACGTATGCCAACGATTTCGGGCTTACGTCGTCGTGGTTATACGCCAGCTTCATTGCGTGAG
TTTTGTCGTCGTATTGGCGTCACTAAACAAGATAATATGGTGGAATTCAGTGCACTAGAAGCTTGCATTCGTGAAGACTT
AAATGAGAATGCGCCACGAGCAATGGCGGTGATTAATCCACTTAAAATTGTGATTGAGAATTTCAGTGGCAAAGAAATGC
TGACTGCACCAAACCACCCTAATCGTGATGAACTAGGTGTACGCGAATTACCCTTTACGCGTGAACTATATATTGATCAA
GCGGATTTCCGTGAAGAAGCAAATAAACAATATAAACGCTTAGTGCTTGGTAAAGAAGTGCGTTTACGTAATGCTTATGT
GATTAAAGCCGAACGTGTTGAAAAAGATGCAGAGGAGAATATCACAACCGTTTATTGTACTTATGACCCTGACACGCTAG
GGAAAAATCCAGCAGATGGACGTAAAGTGAAAGGCGTGATTCAATGGGTGTCTGCGGAAGATTATTTACCAGCTGAATTT
CGTCAATATGGGCGTTTATTTACGGTGGCAAACCCAGGAGCCGCAGAGGATATTCACCAAGTACTGAACCCAGATTCATT
GGTGATTAAACAAGGTGTGGTGGAGAAGAGTTTAGCCAATGCACAGCCAGAAAAAGCTTACCAATTTGAGCGTGAAGGTT
ATTATTGTGCAGACAGCAAAGATAGCCGCCCAGATCATTTGGTCTTCAATTTAACCGTGAGTTTAAAAGAAGGCTTCTAA

Upstream 100 bases:

>100_bases
AAGCCACAAGAAAATGCGGCGTATTTTTGTATTCTGGTGGCAAACAGGGTAGAATAGTGAGTATTTTTATAACAAAACCA
TTATGGAATTCGAGGTCAGA

Downstream 100 bases:

>100_bases
TTTTCTTGCCGTTTGAAGAGCGCTTTTTGAAGCGCTCTTTTTTATGGGCAATTTTTTTGTTGATTAAAAAAATAGCATTT
TATTAGAAATTATCTAATTA

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS

Number of amino acids: Translated: 559; Mature: 558

Protein sequence:

>559_residues
MSHPVENVVAAENTEKRPTNFIRQIIDEDLASGKHTGVQTRFPPEPNGYLHIGHAKSICLNFGIAEDYQGLCNLRFDDTN
PVKEDVEYVDSIKQDVEWLGFKWEGEPRYASDYFDQLYGYAIELIEKGLAYVDELSPEEMREYRGTLTEPGKNSPYRDRS
IEENLALFEKMKNGEIAEGKACLRAKIDMASPFIVMRDPVIYRIKFATHHQTGDKWCIYPMYDFTHCISDAIERITHSLC
TLEFQDNRRLYDWVLENISIARPLPHQYEFSRLNLESTLTSKRKLLQLVNEGIVDGWNDPRMPTISGLRRRGYTPASLRE
FCRRIGVTKQDNMVEFSALEACIREDLNENAPRAMAVINPLKIVIENFSGKEMLTAPNHPNRDELGVRELPFTRELYIDQ
ADFREEANKQYKRLVLGKEVRLRNAYVIKAERVEKDAEENITTVYCTYDPDTLGKNPADGRKVKGVIQWVSAEDYLPAEF
RQYGRLFTVANPGAAEDIHQVLNPDSLVIKQGVVEKSLANAQPEKAYQFEREGYYCADSKDSRPDHLVFNLTVSLKEGF

Sequences:

>Translated_559_residues
MSHPVENVVAAENTEKRPTNFIRQIIDEDLASGKHTGVQTRFPPEPNGYLHIGHAKSICLNFGIAEDYQGLCNLRFDDTN
PVKEDVEYVDSIKQDVEWLGFKWEGEPRYASDYFDQLYGYAIELIEKGLAYVDELSPEEMREYRGTLTEPGKNSPYRDRS
IEENLALFEKMKNGEIAEGKACLRAKIDMASPFIVMRDPVIYRIKFATHHQTGDKWCIYPMYDFTHCISDAIERITHSLC
TLEFQDNRRLYDWVLENISIARPLPHQYEFSRLNLESTLTSKRKLLQLVNEGIVDGWNDPRMPTISGLRRRGYTPASLRE
FCRRIGVTKQDNMVEFSALEACIREDLNENAPRAMAVINPLKIVIENFSGKEMLTAPNHPNRDELGVRELPFTRELYIDQ
ADFREEANKQYKRLVLGKEVRLRNAYVIKAERVEKDAEENITTVYCTYDPDTLGKNPADGRKVKGVIQWVSAEDYLPAEF
RQYGRLFTVANPGAAEDIHQVLNPDSLVIKQGVVEKSLANAQPEKAYQFEREGYYCADSKDSRPDHLVFNLTVSLKEGF
>Mature_558_residues
SHPVENVVAAENTEKRPTNFIRQIIDEDLASGKHTGVQTRFPPEPNGYLHIGHAKSICLNFGIAEDYQGLCNLRFDDTNP
VKEDVEYVDSIKQDVEWLGFKWEGEPRYASDYFDQLYGYAIELIEKGLAYVDELSPEEMREYRGTLTEPGKNSPYRDRSI
EENLALFEKMKNGEIAEGKACLRAKIDMASPFIVMRDPVIYRIKFATHHQTGDKWCIYPMYDFTHCISDAIERITHSLCT
LEFQDNRRLYDWVLENISIARPLPHQYEFSRLNLESTLTSKRKLLQLVNEGIVDGWNDPRMPTISGLRRRGYTPASLREF
CRRIGVTKQDNMVEFSALEACIREDLNENAPRAMAVINPLKIVIENFSGKEMLTAPNHPNRDELGVRELPFTRELYIDQA
DFREEANKQYKRLVLGKEVRLRNAYVIKAERVEKDAEENITTVYCTYDPDTLGKNPADGRKVKGVIQWVSAEDYLPAEFR
QYGRLFTVANPGAAEDIHQVLNPDSLVIKQGVVEKSLANAQPEKAYQFEREGYYCADSKDSRPDHLVFNLTVSLKEGF

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI4826960, Length=531, Percent_Identity=46.3276836158192, Blast_Score=438, Evalue=1e-123,
Organism=Homo sapiens, GI62241042, Length=514, Percent_Identity=33.6575875486381, Blast_Score=275, Evalue=1e-73,
Organism=Escherichia coli, GI1786895, Length=548, Percent_Identity=77.007299270073, Blast_Score=889, Evalue=0.0,
Organism=Escherichia coli, GI1788743, Length=303, Percent_Identity=23.4323432343234, Blast_Score=74, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17543332, Length=540, Percent_Identity=41.4814814814815, Blast_Score=402, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17511007, Length=512, Percent_Identity=34.1796875, Blast_Score=266, Evalue=2e-71,
Organism=Saccharomyces cerevisiae, GI6324742, Length=563, Percent_Identity=39.7868561278863, Blast_Score=376, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6321192, Length=526, Percent_Identity=36.1216730038023, Blast_Score=311, Evalue=2e-85,
Organism=Drosophila melanogaster, GI17864488, Length=552, Percent_Identity=42.5724637681159, Blast_Score=415, Evalue=1e-116,
Organism=Drosophila melanogaster, GI24649466, Length=519, Percent_Identity=36.0308285163777, Blast_Score=279, Evalue=4e-75,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYQ_PASMU (P57847)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245465.1
- ProteinModelPortal:   P57847
- SMR:   P57847
- PRIDE:   P57847
- GeneID:   1243875
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0528
- NMPDR:   fig|272843.1.peg.528
- HOGENOM:   HBG334108
- OMA:   RMPTIAG
- ProtClustDB:   PRK05347
- BioCyc:   PMUL272843:PM0528-MONOMER
- BRENDA:   6.1.1.18
- GO:   GO:0005737
- HAMAP:   MF_00126
- InterPro:   IPR001412
- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729
- Gene3D:   G3DSA:1.10.1160.10
- Gene3D:   G3DSA:2.40.240.10
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR10119:SF3
- PANTHER:   PTHR10119
- PRINTS:   PR00987
- TIGRFAMs:   TIGR00440

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C; SSF50715 Ribosomal_L25rel

EC number: =6.1.1.18

Molecular weight: Translated: 64310; Mature: 64179

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 282-282

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHPVENVVAAENTEKRPTNFIRQIIDEDLASGKHTGVQTRFPPEPNGYLHIGHAKSICL
CCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCHHHHHE
NFGIAEDYQGLCNLRFDDTNPVKEDVEYVDSIKQDVEWLGFKWEGEPRYASDYFDQLYGY
ECCCCCCCHHHEEEECCCCCCHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHH
AIELIEKGLAYVDELSPEEMREYRGTLTEPGKNSPYRDRSIEENLALFEKMKNGEIAEGK
HHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCC
ACLRAKIDMASPFIVMRDPVIYRIKFATHHQTGDKWCIYPMYDFTHCISDAIERITHSLC
HHHHEECCCCCCEEEEECCEEEEEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHE
TLEFQDNRRLYDWVLENISIARPLPHQYEFSRLNLESTLTSKRKLLQLVNEGIVDGWNDP
EEEECCCCHHHHHHHHCCHHCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCC
RMPTISGLRRRGYTPASLREFCRRIGVTKQDNMVEFSALEACIREDLNENAPRAMAVINP
CCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
LKIVIENFSGKEMLTAPNHPNRDELGVRELPFTRELYIDQADFREEANKQYKRLVLGKEV
HHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCE
RLRNAYVIKAERVEKDAEENITTVYCTYDPDTLGKNPADGRKVKGVIQWVSAEDYLPAEF
EECCEEEEEHHHHHCHHHCCCEEEEEEECCHHCCCCCCCCHHHHHHHHHHCCCCCCCHHH
RQYGRLFTVANPGAAEDIHQVLNPDSLVIKQGVVEKSLANAQPEKAYQFEREGYYCADSK
HHCCCEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCEEECCCC
DSRPDHLVFNLTVSLKEGF
CCCCCEEEEEEEEEECCCC
>Mature Secondary Structure 
SHPVENVVAAENTEKRPTNFIRQIIDEDLASGKHTGVQTRFPPEPNGYLHIGHAKSICL
CCCHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCHHHHHE
NFGIAEDYQGLCNLRFDDTNPVKEDVEYVDSIKQDVEWLGFKWEGEPRYASDYFDQLYGY
ECCCCCCCHHHEEEECCCCCCHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHH
AIELIEKGLAYVDELSPEEMREYRGTLTEPGKNSPYRDRSIEENLALFEKMKNGEIAEGK
HHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCC
ACLRAKIDMASPFIVMRDPVIYRIKFATHHQTGDKWCIYPMYDFTHCISDAIERITHSLC
HHHHEECCCCCCEEEEECCEEEEEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHE
TLEFQDNRRLYDWVLENISIARPLPHQYEFSRLNLESTLTSKRKLLQLVNEGIVDGWNDP
EEEECCCCHHHHHHHHCCHHCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCC
RMPTISGLRRRGYTPASLREFCRRIGVTKQDNMVEFSALEACIREDLNENAPRAMAVINP
CCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
LKIVIENFSGKEMLTAPNHPNRDELGVRELPFTRELYIDQADFREEANKQYKRLVLGKEV
HHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCE
RLRNAYVIKAERVEKDAEENITTVYCTYDPDTLGKNPADGRKVKGVIQWVSAEDYLPAEF
EECCEEEEEHHHHHCHHHCCCEEEEEEECCHHCCCCCCCCHHHHHHHHHHCCCCCCCHHH
RQYGRLFTVANPGAAEDIHQVLNPDSLVIKQGVVEKSLANAQPEKAYQFEREGYYCADSK
HHCCCEEEECCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCEEECCCC
DSRPDHLVFNLTVSLKEGF
CCCCCEEEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100