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The map label for this gene is cusC [C]

Identifier: 15602392

GI number: 15602392

Start: 602101

End: 603468

Strand: Reverse

Name: cusC [C]

Synonym: PM0527

Alternate gene names: 15602392

Gene position: 603468-602101 (Counterclockwise)

Preceding gene: 15602397

Following gene: 15602391

Centisome position: 26.73

GC content: 40.2

Gene sequence:

>1368_bases
ATGTTAAAACGAAACCCACTCACTTTTTTACTCTTATCAACCGCTTTGGTTGGTTGTGCTAATCTGGATGATTCTTATCA
ACTCGCCAAACAAGACTTTCAACAGTATGAAGAGGTGACAAAACAATATTCTGTGCAAGAAAGTTGGTGGGCGCTATATC
ATGATACACAACTCAATGCATTGATTACGCAAGGATTAGACAACAATAAAAATTTGGCTAAAGCCGCCATCAATGTGAAT
AAAGCACTTTATCAAGCCAATTTATTAGGTGCAAATTTAGTTCCAGCCTTTAGTGGCAGAGTCGAATCCAGTGCAACACG
TAACATAGAACACAGTCAACCTTCCAAGATTCAGCATAGTGGTTCAATCAATGTCAGCTATACATTAGATTTATGGCGAC
GCTTAGCCGATGCGGCTTCGGCTGGTGAGTGGGCATACAAAGCGAGCGCCCAAGATCTTGAAGCCGCCCGTTTATCACTC
ATCAATTCTCTCATCGCAACCTATTACCAAATTGCTTTCTTAAATGATGCGCTACAAGCGACAGAAGGAACAATTAAATA
TTACACGCAGATTAATACTATCATGCAAAATCGTTTTAAACTCGGTGTAGCAGACAGTGCGAGTTCTGATCAAACACAGC
AAGCCGTATTAAGAGCGCGTAACCAGTTGATCACCTACCAAACGCAGCGAAAAGTGGCAGAGCAAACTTTACGTAATTTA
TTAAATTTAAAACCAAATGAAGCATTAAATATCAAATTCCCAAGCATTTTAAATGTGAAAACGCTTGGAGTGAATACTAA
TGTGCCTGTCTCAACAATTGCGAACCGACCAGATATTAAAAGCGCACAATACCGTTTAAGCAGCGCCTTCAAAGATGCTA
AAGCTGTTCAAAAGAGTTGGTTCCCAACCATCACACTGGGCGCAAGCCTAGCCTCTGCAGGAGCGAAAGTTGATACCGCG
TTAGATACCCCTATGGCTAGTGGACTCGTCAGTATTAATCTGCCTTTCCTCAGTTGGAATACGGTAAAATGGAACGTCAA
AATTTCAGAAGCAAATTATGAACTCGCCAAAGTGAGCTATGAACAAACGATCACCACGGCATTAAATGAAATTGATACCC
ATTATTTCAGCTATCAACAATCACAAGCGAATTTAGCGAATCTACAAAAAGCAGATGCCTATAACAAACGCATTACACAG
TATTACAAAAATCGCTATGATGCAGGCGTATCACCGTTACGTGATTGGTTAAGTGCCGCCAATACGGAGAATGATGCGAA
ATTGGCGATTTTAAATGCAAAATATCAACTTATTCAGCAAGAAAATACTATTTATAGCGCCATGGCAGGGTATTACTCAG
CAAAATAA

Upstream 100 bases:

>100_bases
AATTGCAATGAAGGTTTTAGCACGTAAAGAGAAAAGTTGCTATAATCCATTCTCGCAAATGGTAAAGGCAACTCGCATTT
TTTAACTAAGGATTGTAATC

Downstream 100 bases:

>100_bases
CAAGAAAGAGGCAACTTGCCTCTTTTTTATTAACAAGAATCTTGGATAACTTCTCATGAAAATCGAAGTCTGTATTGATA
ATATTGAATCGGTACACATT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MLKRNPLTFLLLSTALVGCANLDDSYQLAKQDFQQYEEVTKQYSVQESWWALYHDTQLNALITQGLDNNKNLAKAAINVN
KALYQANLLGANLVPAFSGRVESSATRNIEHSQPSKIQHSGSINVSYTLDLWRRLADAASAGEWAYKASAQDLEAARLSL
INSLIATYYQIAFLNDALQATEGTIKYYTQINTIMQNRFKLGVADSASSDQTQQAVLRARNQLITYQTQRKVAEQTLRNL
LNLKPNEALNIKFPSILNVKTLGVNTNVPVSTIANRPDIKSAQYRLSSAFKDAKAVQKSWFPTITLGASLASAGAKVDTA
LDTPMASGLVSINLPFLSWNTVKWNVKISEANYELAKVSYEQTITTALNEIDTHYFSYQQSQANLANLQKADAYNKRITQ
YYKNRYDAGVSPLRDWLSAANTENDAKLAILNAKYQLIQQENTIYSAMAGYYSAK

Sequences:

>Translated_455_residues
MLKRNPLTFLLLSTALVGCANLDDSYQLAKQDFQQYEEVTKQYSVQESWWALYHDTQLNALITQGLDNNKNLAKAAINVN
KALYQANLLGANLVPAFSGRVESSATRNIEHSQPSKIQHSGSINVSYTLDLWRRLADAASAGEWAYKASAQDLEAARLSL
INSLIATYYQIAFLNDALQATEGTIKYYTQINTIMQNRFKLGVADSASSDQTQQAVLRARNQLITYQTQRKVAEQTLRNL
LNLKPNEALNIKFPSILNVKTLGVNTNVPVSTIANRPDIKSAQYRLSSAFKDAKAVQKSWFPTITLGASLASAGAKVDTA
LDTPMASGLVSINLPFLSWNTVKWNVKISEANYELAKVSYEQTITTALNEIDTHYFSYQQSQANLANLQKADAYNKRITQ
YYKNRYDAGVSPLRDWLSAANTENDAKLAILNAKYQLIQQENTIYSAMAGYYSAK
>Mature_455_residues
MLKRNPLTFLLLSTALVGCANLDDSYQLAKQDFQQYEEVTKQYSVQESWWALYHDTQLNALITQGLDNNKNLAKAAINVN
KALYQANLLGANLVPAFSGRVESSATRNIEHSQPSKIQHSGSINVSYTLDLWRRLADAASAGEWAYKASAQDLEAARLSL
INSLIATYYQIAFLNDALQATEGTIKYYTQINTIMQNRFKLGVADSASSDQTQQAVLRARNQLITYQTQRKVAEQTLRNL
LNLKPNEALNIKFPSILNVKTLGVNTNVPVSTIANRPDIKSAQYRLSSAFKDAKAVQKSWFPTITLGASLASAGAKVDTA
LDTPMASGLVSINLPFLSWNTVKWNVKISEANYELAKVSYEQTITTALNEIDTHYFSYQQSQANLANLQKADAYNKRITQ
YYKNRYDAGVSPLRDWLSAANTENDAKLAILNAKYQLIQQENTIYSAMAGYYSAK

Specific function: In Pathogenic Strains It Allows The Bacteria To Invade Brain Microvascular Endothelial Cells (Bmec) Thus Allowing It To Cross The Blood-Brain Barrier And Cause Neonatal Meningitis. [C]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Attached To The Outer Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=460, Percent_Identity=22.6086956521739, Blast_Score=99, Evalue=8e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 50683; Mature: 50683

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKRNPLTFLLLSTALVGCANLDDSYQLAKQDFQQYEEVTKQYSVQESWWALYHDTQLNA
CCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHEEEEECCHHHH
LITQGLDNNKNLAKAAINVNKALYQANLLGANLVPAFSGRVESSATRNIEHSQPSKIQHS
HHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCHHHCCCCCCCCCCCCCC
GSINVSYTLDLWRRLADAASAGEWAYKASAQDLEAARLSLINSLIATYYQIAFLNDALQA
CCEEEEEHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TEGTIKYYTQINTIMQNRFKLGVADSASSDQTQQAVLRARNQLITYQTQRKVAEQTLRNL
CCCHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHH
LNLKPNEALNIKFPSILNVKTLGVNTNVPVSTIANRPDIKSAQYRLSSAFKDAKAVQKSW
HCCCCCCEEEEECCCEEEEEEECCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHC
FPTITLGASLASAGAKVDTALDTPMASGLVSINLPFLSWNTVKWNVKISEANYELAKVSY
CCEEEECHHHHHCCCCCHHHHCCHHHCCEEEEEECEEEECEEEEEEEEECCCCCHHHHHH
EQTITTALNEIDTHYFSYQQSQANLANLQKADAYNKRITQYYKNRYDAGVSPLRDWLSAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHC
NTENDAKLAILNAKYQLIQQENTIYSAMAGYYSAK
CCCCCCEEEEEEHHHHHHHHCCHHHHHHHHHHCCC
>Mature Secondary Structure
MLKRNPLTFLLLSTALVGCANLDDSYQLAKQDFQQYEEVTKQYSVQESWWALYHDTQLNA
CCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHEEEEECCHHHH
LITQGLDNNKNLAKAAINVNKALYQANLLGANLVPAFSGRVESSATRNIEHSQPSKIQHS
HHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCHHHCCCCCCCCCCCCCC
GSINVSYTLDLWRRLADAASAGEWAYKASAQDLEAARLSLINSLIATYYQIAFLNDALQA
CCEEEEEHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TEGTIKYYTQINTIMQNRFKLGVADSASSDQTQQAVLRARNQLITYQTQRKVAEQTLRNL
CCCHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHH
LNLKPNEALNIKFPSILNVKTLGVNTNVPVSTIANRPDIKSAQYRLSSAFKDAKAVQKSW
HCCCCCCEEEEECCCEEEEEEECCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHC
FPTITLGASLASAGAKVDTALDTPMASGLVSINLPFLSWNTVKWNVKISEANYELAKVSY
CCEEEECHHHHHCCCCCHHHHCCHHHCCEEEEEECEEEECEEEEEEEEECCCCCHHHHHH
EQTITTALNEIDTHYFSYQQSQANLANLQKADAYNKRITQYYKNRYDAGVSPLRDWLSAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHC
NTENDAKLAILNAKYQLIQQENTIYSAMAGYYSAK
CCCCCCEEEEEEHHHHHHHHCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]