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The map label for this gene is glmM

Identifier: 15602305

GI number: 15602305

Start: 516063

End: 517397

Strand: Direct

Name: glmM

Synonym: PM0440

Alternate gene names: 15602305

Gene position: 516063-517397 (Clockwise)

Preceding gene: 15602304

Following gene: 15602306

Centisome position: 22.86

GC content: 44.42

Gene sequence:

>1335_bases
ATGGCAGAACGTAAGTATTTTGGTACAGATGGTGTCCGCGGCAAAGTGGGAACATTCCCAATTACCCCTGATTTTGCTTT
AAAATTGGGTTGGGCTGCCGGCAAAGTCTTGGCGACGCAAGGGTCAAGAACCGTATTAATTGGTAAAGATACCCGTATTT
CAGGGTATATGTTGGAATCAGCACTTGAAGCGGGTTTAGCGGCGGCAGGGCTCTCAGCGGCGTTCACCGGACCGATGCCA
ACTCCGGCTATTGCTTATTTAACACGCACATTTCGTGCAGAAGCGGGGATTGTCATCTCGGCATCGCACAACCCTTATTA
TGATAATGGCATTAAGTTTTTTTCTGCCCAAGGGACAAAATTACCAGATGATGTAGAAGAAGCGATTGAAGCTATGCTGG
ATGAACCGATGGATTGTGTCGAATCTGCGGAGCTTGGTCGAGCAAGCCGGATTAATGATGCGGTAGGACGTTATATTGAG
TTTTGTAAAGGAACGTTTCCCGCTCACCTGAGTTTAGAAAACTATAAAATTGTTGTGGATTGTGCTCATGGTGCAACCTA
TCACATTGCACCGAATGTAATGCGTGAACTGGGCGCAGAAGTGATAGAAATCGGTGCTAAGCCAAATGGGCTGAATATTA
ATGAGAAATGTGGTGCCACCGATATCAAAGCACTGCAAGAGAAAGTGCTTGAAGTGAAAGCCGATGTGGGACTTGCCTAT
GATGGTGATGGAGACCGTTTAATTATGGTTGACCATTTAGGCAATAAAGTCGATGGTGATCAAGTTTTATTTATTATTGC
GCGTGAAGCTTTACGTGCAGGTCATTTAAAAGGTGGTGTGGTGGGCACCTTAATGAGTAATATGAGTCTTGAACTTGCGT
TAAAACAGTTAGGCATTCCGTTTGTTCGTGCCAATGTGGGTGACCGTTATGTGTTGGAGAAAATGCAAGAAAAAGGCTGG
TTATTGGGAGGGGAAAACTCCGGGCATATTATTATTTTAGATAAAAACACCACTGGAGATGGCATTATTGCTTCCTTAGC
CGTATTAAGTGCGATGGTACAGCATAACTTATCTTTAAATGAGTTAGCCAGTGCTGTGCCGCTTTTCCCACAAGTGTTAA
TTAATGTACGTTTTGCTGGGGGAGATAATCCACTCGAAAGCGCTGCGGTAAAAGCAGTTGCCGCAGAGGTTGAAAAACGT
TTGGCAGGCAAAGGGCGCATTTTATTACGTAAGTCGGGTACTGAACCTTTAATTCGAGTCATGGTAGAATGTGAAGATGG
TGCATTAGCTCAACAATGTGCAGAACAGATTGCGGATGTTGTGCGAGCTAACTAA

Upstream 100 bases:

>100_bases
GTGCAGCAATTGTACGTGTGCATGATGTTGAACACACAGCGGATGCGCTCAAAATTTGGCAAGCAACAAAGAATGCTTAA
ATAAAGAAGGATGGATAAAT

Downstream 100 bases:

>100_bases
TGTTTTTTTGAGTAAGCTGAGTCGATAAGGCTCAGTTTATTTTTTAATATTGAGAGTCAATTATGGATATTTTTGTTATG
CGCCATGGCGAAGCCGAAGT

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MAERKYFGTDGVRGKVGTFPITPDFALKLGWAAGKVLATQGSRTVLIGKDTRISGYMLESALEAGLAAAGLSAAFTGPMP
TPAIAYLTRTFRAEAGIVISASHNPYYDNGIKFFSAQGTKLPDDVEEAIEAMLDEPMDCVESAELGRASRINDAVGRYIE
FCKGTFPAHLSLENYKIVVDCAHGATYHIAPNVMRELGAEVIEIGAKPNGLNINEKCGATDIKALQEKVLEVKADVGLAY
DGDGDRLIMVDHLGNKVDGDQVLFIIAREALRAGHLKGGVVGTLMSNMSLELALKQLGIPFVRANVGDRYVLEKMQEKGW
LLGGENSGHIIILDKNTTGDGIIASLAVLSAMVQHNLSLNELASAVPLFPQVLINVRFAGGDNPLESAAVKAVAAEVEKR
LAGKGRILLRKSGTEPLIRVMVECEDGALAQQCAEQIADVVRAN

Sequences:

>Translated_444_residues
MAERKYFGTDGVRGKVGTFPITPDFALKLGWAAGKVLATQGSRTVLIGKDTRISGYMLESALEAGLAAAGLSAAFTGPMP
TPAIAYLTRTFRAEAGIVISASHNPYYDNGIKFFSAQGTKLPDDVEEAIEAMLDEPMDCVESAELGRASRINDAVGRYIE
FCKGTFPAHLSLENYKIVVDCAHGATYHIAPNVMRELGAEVIEIGAKPNGLNINEKCGATDIKALQEKVLEVKADVGLAY
DGDGDRLIMVDHLGNKVDGDQVLFIIAREALRAGHLKGGVVGTLMSNMSLELALKQLGIPFVRANVGDRYVLEKMQEKGW
LLGGENSGHIIILDKNTTGDGIIASLAVLSAMVQHNLSLNELASAVPLFPQVLINVRFAGGDNPLESAAVKAVAAEVEKR
LAGKGRILLRKSGTEPLIRVMVECEDGALAQQCAEQIADVVRAN
>Mature_443_residues
AERKYFGTDGVRGKVGTFPITPDFALKLGWAAGKVLATQGSRTVLIGKDTRISGYMLESALEAGLAAAGLSAAFTGPMPT
PAIAYLTRTFRAEAGIVISASHNPYYDNGIKFFSAQGTKLPDDVEEAIEAMLDEPMDCVESAELGRASRINDAVGRYIEF
CKGTFPAHLSLENYKIVVDCAHGATYHIAPNVMRELGAEVIEIGAKPNGLNINEKCGATDIKALQEKVLEVKADVGLAYD
GDGDRLIMVDHLGNKVDGDQVLFIIAREALRAGHLKGGVVGTLMSNMSLELALKQLGIPFVRANVGDRYVLEKMQEKGWL
LGGENSGHIIILDKNTTGDGIIASLAVLSAMVQHNLSLNELASAVPLFPQVLINVRFAGGDNPLESAAVKAVAAEVEKRL
AGKGRILLRKSGTEPLIRVMVECEDGALAQQCAEQIADVVRAN

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=444, Percent_Identity=73.6486486486486, Blast_Score=652, Evalue=0.0,
Organism=Escherichia coli, GI1788361, Length=454, Percent_Identity=26.6519823788546, Blast_Score=100, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17535441, Length=409, Percent_Identity=25.9168704156479, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_PASMU (Q9CNJ0)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245377.1
- ProteinModelPortal:   Q9CNJ0
- SMR:   Q9CNJ0
- GeneID:   1243787
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0440
- NMPDR:   fig|272843.1.peg.440
- HOGENOM:   HBG644964
- OMA:   VHDRYIE
- ProtClustDB:   PRK10887
- BioCyc:   PMUL272843:PM0440-MONOMER
- BRENDA:   5.4.2.10
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 47329; Mature: 47198

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 102-102

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAERKYFGTDGVRGKVGTFPITPDFALKLGWAAGKVLATQGSRTVLIGKDTRISGYMLES
CCCCCCCCCCCCCCCCCCCCCCCCHHEEECCCCCEEEEECCCEEEEEECCCCCHHHHHHH
ALEAGLAAAGLSAAFTGPMPTPAIAYLTRTFRAEAGIVISASHNPYYDNGIKFFSAQGTK
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEECCCCC
LPDDVEEAIEAMLDEPMDCVESAELGRASRINDAVGRYIEFCKGTFPAHLSLENYKIVVD
CCHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEEE
CAHGATYHIAPNVMRELGAEVIEIGAKPNGLNINEKCGATDIKALQEKVLEVKADVGLAY
ECCCCEEEECHHHHHHHCHHHEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEE
DGDGDRLIMVDHLGNKVDGDQVLFIIAREALRAGHLKGGVVGTLMSNMSLELALKQLGIP
ECCCCEEEEEECCCCCCCCCCEEEEEEHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHCCC
FVRANVGDRYVLEKMQEKGWLLGGENSGHIIILDKNTTGDGIIASLAVLSAMVQHNLSLN
EEECCCCCHHHHHHHHHCCCEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCHH
ELASAVPLFPQVLINVRFAGGDNPLESAAVKAVAAEVEKRLAGKGRILLRKSGTEPLIRV
HHHHHHCCCCEEHEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEE
MVECEDGALAQQCAEQIADVVRAN
EEECCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AERKYFGTDGVRGKVGTFPITPDFALKLGWAAGKVLATQGSRTVLIGKDTRISGYMLES
CCCCCCCCCCCCCCCCCCCCCCCHHEEECCCCCEEEEECCCEEEEEECCCCCHHHHHHH
ALEAGLAAAGLSAAFTGPMPTPAIAYLTRTFRAEAGIVISASHNPYYDNGIKFFSAQGTK
HHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEECCCCC
LPDDVEEAIEAMLDEPMDCVESAELGRASRINDAVGRYIEFCKGTFPAHLSLENYKIVVD
CCHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEECCEEEEEE
CAHGATYHIAPNVMRELGAEVIEIGAKPNGLNINEKCGATDIKALQEKVLEVKADVGLAY
ECCCCEEEECHHHHHHHCHHHEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEE
DGDGDRLIMVDHLGNKVDGDQVLFIIAREALRAGHLKGGVVGTLMSNMSLELALKQLGIP
ECCCCEEEEEECCCCCCCCCCEEEEEEHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHCCC
FVRANVGDRYVLEKMQEKGWLLGGENSGHIIILDKNTTGDGIIASLAVLSAMVQHNLSLN
EEECCCCCHHHHHHHHHCCCEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCHH
ELASAVPLFPQVLINVRFAGGDNPLESAAVKAVAAEVEKRLAGKGRILLRKSGTEPLIRV
HHHHHHCCCCEEHEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEE
MVECEDGALAQQCAEQIADVVRAN
EEECCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100