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The map label for this gene is fdhE

Identifier: 15602270

GI number: 15602270

Start: 473650

End: 474579

Strand: Reverse

Name: fdhE

Synonym: PM0405

Alternate gene names: 15602270

Gene position: 474579-473650 (Counterclockwise)

Preceding gene: 15602271

Following gene: 15602268

Centisome position: 21.02

GC content: 43.33

Gene sequence:

>930_bases
ATGAGTATCCGAATTCTTCCCGACTCTGAAATTAAAGCGGCCGCCAGTTCATTTCATGCACCGGCACTCCTGTTTGCAAA
CCCGAAAAATCTCTATCAACGTCGTATTGCACGTTTCACTTCGCTTTCAAATGCACATCCATTGGAAGACTATCTTCACT
TTGCAAGCCAAGTTGCCGAAGCACAATTAGCAGTCTTGCAACAACAACCAATTGCACAAGACCCGCGTTTAAGCGCAGAA
AAACTCTCTGCCGAAGATCTTGCTAAACAACCACTTAACGCTCAACGCTGGCAGCGCGATCCTGTTTGGCAAACCTTATT
AATGGCAATTTTGGCGGAAATGAAACCCAAAGCCAATGAGACGATTCTCAATACGATTGAAACCTTAGAGAAATACTCAA
AAGCGGAACGAGATAGCATCGCGGATAAACTCTTAGCTCAAGAATTTGAGCAAATTAGCAGTGCTCAAGCCGTTTTCATT
TGGGCGGCACTTTCCCTTTACTGGCTTCAATTAGTACAACAAATTCCGCATTCAAGTCATAAAGAAAGCGGAGAGAGCCT
TCATGTTTGCCCAATTTGTGCCTCTGCACCTGTCACTAGCGTGATTCATTTTGGCGCTGAACAAGGCTTACGTTACTTAC
ATTGTGCCTTGTGTGAAACTGAGTGGAATATGGTTCGTTCAAAATGTACGAATTGTGACCAAACGGGTAAATTAGATTAT
TGGTCTCTTGATTCTGAAATAGCGGCAGTGAAAGCAGAAAGTTGCGGTGATTGTCATAGCTACTTAAAAGCACTATACCA
AGAACGTGATCCTAAAGTAGAAGCCGTAGCCGATGATCTTGCTAGCATTTTCCTAGATGTGGAAATGGAAGAAAAAGGCT
TACAACGCAGTGGCTTAAATCCTTTCCTCTTCCCAAACCCAGAAGCCTAA

Upstream 100 bases:

>100_bases
CCAACCATAAACACGACTCTGTGAATAAAAGTGCGGTCAAATTTTCAGAAATTTTTCTAAAAACGACCGCACTTTATTTA
TTCAAAAATAAGGAAACATG

Downstream 100 bases:

>100_bases
TCTTCATCTATAAACAAAAGCAAGGTTATCCTTGCTTTTGTTATTTTTCTCATTCAAATTGGCTAAAAAAATCTCCTATC
TTAAATAGCATACATTATTA

Product: formate dehydrogenase accessory protein FdhE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MSIRILPDSEIKAAASSFHAPALLFANPKNLYQRRIARFTSLSNAHPLEDYLHFASQVAEAQLAVLQQQPIAQDPRLSAE
KLSAEDLAKQPLNAQRWQRDPVWQTLLMAILAEMKPKANETILNTIETLEKYSKAERDSIADKLLAQEFEQISSAQAVFI
WAALSLYWLQLVQQIPHSSHKESGESLHVCPICASAPVTSVIHFGAEQGLRYLHCALCETEWNMVRSKCTNCDQTGKLDY
WSLDSEIAAVKAESCGDCHSYLKALYQERDPKVEAVADDLASIFLDVEMEEKGLQRSGLNPFLFPNPEA

Sequences:

>Translated_309_residues
MSIRILPDSEIKAAASSFHAPALLFANPKNLYQRRIARFTSLSNAHPLEDYLHFASQVAEAQLAVLQQQPIAQDPRLSAE
KLSAEDLAKQPLNAQRWQRDPVWQTLLMAILAEMKPKANETILNTIETLEKYSKAERDSIADKLLAQEFEQISSAQAVFI
WAALSLYWLQLVQQIPHSSHKESGESLHVCPICASAPVTSVIHFGAEQGLRYLHCALCETEWNMVRSKCTNCDQTGKLDY
WSLDSEIAAVKAESCGDCHSYLKALYQERDPKVEAVADDLASIFLDVEMEEKGLQRSGLNPFLFPNPEA
>Mature_308_residues
SIRILPDSEIKAAASSFHAPALLFANPKNLYQRRIARFTSLSNAHPLEDYLHFASQVAEAQLAVLQQQPIAQDPRLSAEK
LSAEDLAKQPLNAQRWQRDPVWQTLLMAILAEMKPKANETILNTIETLEKYSKAERDSIADKLLAQEFEQISSAQAVFIW
AALSLYWLQLVQQIPHSSHKESGESLHVCPICASAPVTSVIHFGAEQGLRYLHCALCETEWNMVRSKCTNCDQTGKLDYW
SLDSEIAAVKAESCGDCHSYLKALYQERDPKVEAVADDLASIFLDVEMEEKGLQRSGLNPFLFPNPEA

Specific function: Necessary for formate dehydrogenase activity

COG id: COG3058

COG function: function code O; Uncharacterized protein involved in formate dehydrogenase formation

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fdhE family

Homologues:

Organism=Escherichia coli, GI1790324, Length=308, Percent_Identity=52.2727272727273, Blast_Score=323, Evalue=1e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FDHE_PASMU (Q9CNM2)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245342.1
- ProteinModelPortal:   Q9CNM2
- SMR:   Q9CNM2
- GeneID:   1243752
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0405
- NMPDR:   fig|272843.1.peg.405
- HOGENOM:   HBG678838
- OMA:   LCACEWH
- ProtClustDB:   PRK03564
- BioCyc:   PMUL272843:PM0405-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00611
- InterPro:   IPR006452
- PIRSF:   PIRSF018296
- TIGRFAMs:   TIGR01562

Pfam domain/function: PF04216 FdhE

EC number: NA

Molecular weight: Translated: 34612; Mature: 34480

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIRILPDSEIKAAASSFHAPALLFANPKNLYQRRIARFTSLSNAHPLEDYLHFASQVAE
CEEEECCCHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
AQLAVLQQQPIAQDPRLSAEKLSAEDLAKQPLNAQRWQRDPVWQTLLMAILAEMKPKANE
HHHHHHHHCCCCCCCCCCHHHCCHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHCCCCHH
TILNTIETLEKYSKAERDSIADKLLAQEFEQISSAQAVFIWAALSLYWLQLVQQIPHSSH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
KESGESLHVCPICASAPVTSVIHFGAEQGLRYLHCALCETEWNMVRSKCTNCDQTGKLDY
CCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCE
WSLDSEIAAVKAESCGDCHSYLKALYQERDPKVEAVADDLASIFLDVEMEEKGLQRSGLN
ECCCCHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCC
PFLFPNPEA
CCCCCCCCC
>Mature Secondary Structure 
SIRILPDSEIKAAASSFHAPALLFANPKNLYQRRIARFTSLSNAHPLEDYLHFASQVAE
EEEECCCHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
AQLAVLQQQPIAQDPRLSAEKLSAEDLAKQPLNAQRWQRDPVWQTLLMAILAEMKPKANE
HHHHHHHHCCCCCCCCCCHHHCCHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHCCCCHH
TILNTIETLEKYSKAERDSIADKLLAQEFEQISSAQAVFIWAALSLYWLQLVQQIPHSSH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
KESGESLHVCPICASAPVTSVIHFGAEQGLRYLHCALCETEWNMVRSKCTNCDQTGKLDY
CCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCE
WSLDSEIAAVKAESCGDCHSYLKALYQERDPKVEAVADDLASIFLDVEMEEKGLQRSGLN
ECCCCHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCC
PFLFPNPEA
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100