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The map label for this gene is sucD [H]

Identifier: 15602146

GI number: 15602146

Start: 320079

End: 320948

Strand: Direct

Name: sucD [H]

Synonym: PM0281

Alternate gene names: 15602146

Gene position: 320079-320948 (Clockwise)

Preceding gene: 15602145

Following gene: 15602147

Centisome position: 14.18

GC content: 47.47

Gene sequence:

>870_bases
ATGTCTATTTTAATTAATAAAGATACCAAAGTGATTTGCCAAGGCTTTACTGGCGGACAAGGCACTTTCCACTCTGAACA
AGCATTGGCTTACGGTACGCAATTGGTCGGTGGTGTTTCGCCGGGTAAAGGCGGCACAACCCATTTAGGCTTACCGGTGT
TTAATACCGTGCGTGATGCGGTTGACGCCACGGGTGCTACGGCTAGCGTGATTTATGTCCCGGCACCAGGTTGTAAAGAT
GCGATTTTGGAAGCCATTGATGCGGGCATTCAGTTAGTGATTTGTATCACTGAAGGGATCCCAACCCTAGATATGTTACA
AGTAAAACAACGCTTGAATCAAACTGGCGTGCGTATGATTGGTCCTAACTGTCCTGGCGTGATTACGCCAGAAGAATGTA
AGATCGGGATTATGCCGGGCAATATTCACAAAAAAGGTAAAATCGGTATTGTTTCACGCTCCGGTACCTTGACCTATGAA
GCGGTCAAACAAACCACTGATGAAGGTTTTGGACAGTCCACTTGTGTGGGAATTGGTGGCGATCCAATCCCTGGGTCAAA
CTTTATTGATATTTTGAAACTGTTCCAAGATGATCCACAAACCGAAGCGATCGTGATGATCGGCGAAATCGGTGGTTCCG
CAGAAGAAGAAGCGGCTGCTTTTATTAAAGACTATGTGACTAAGCCCGTCGTGAGCTATATTGCTGGGGTCACCGCACCA
AAAGGTAAGCGTATGGGACACGCAGGCGCGATTATCAGTGGGGGCAAAGGCACCGCAGATGAAAAATTCGCCGCCCTTGA
AGCTGCTGGTGTGAAAACGGTACGCAGTTTAGCGGAAATCGGCGCAGCGTTAAAAGCACTGTTAAAATAG

Upstream 100 bases:

>100_bases
GGTCGTGAGATTTTAGCAAACAGTGGTGTGAATATTATTGCGGCAAATACTTTAACGGATGCTGCGATTCAAGCTGTGAA
AGCCGCGGAGGGAAAATAAG

Downstream 100 bases:

>100_bases
TCCACATTAAAGATCTGCACTCAGGGGGCTGTATAAGAAACAGTCCACTGGGGGCGGATTTTTTTATAACTAAACAGTAT
TTTAAATATGCATAAGTGGT

Product: hypothetical protein

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MSILINKDTKVICQGFTGGQGTFHSEQALAYGTQLVGGVSPGKGGTTHLGLPVFNTVRDAVDATGATASVIYVPAPGCKD
AILEAIDAGIQLVICITEGIPTLDMLQVKQRLNQTGVRMIGPNCPGVITPEECKIGIMPGNIHKKGKIGIVSRSGTLTYE
AVKQTTDEGFGQSTCVGIGGDPIPGSNFIDILKLFQDDPQTEAIVMIGEIGGSAEEEAAAFIKDYVTKPVVSYIAGVTAP
KGKRMGHAGAIISGGKGTADEKFAALEAAGVKTVRSLAEIGAALKALLK

Sequences:

>Translated_289_residues
MSILINKDTKVICQGFTGGQGTFHSEQALAYGTQLVGGVSPGKGGTTHLGLPVFNTVRDAVDATGATASVIYVPAPGCKD
AILEAIDAGIQLVICITEGIPTLDMLQVKQRLNQTGVRMIGPNCPGVITPEECKIGIMPGNIHKKGKIGIVSRSGTLTYE
AVKQTTDEGFGQSTCVGIGGDPIPGSNFIDILKLFQDDPQTEAIVMIGEIGGSAEEEAAAFIKDYVTKPVVSYIAGVTAP
KGKRMGHAGAIISGGKGTADEKFAALEAAGVKTVRSLAEIGAALKALLK
>Mature_288_residues
SILINKDTKVICQGFTGGQGTFHSEQALAYGTQLVGGVSPGKGGTTHLGLPVFNTVRDAVDATGATASVIYVPAPGCKDA
ILEAIDAGIQLVICITEGIPTLDMLQVKQRLNQTGVRMIGPNCPGVITPEECKIGIMPGNIHKKGKIGIVSRSGTLTYEA
VKQTTDEGFGQSTCVGIGGDPIPGSNFIDILKLFQDDPQTEAIVMIGEIGGSAEEEAAAFIKDYVTKPVVSYIAGVTAPK
GKRMGHAGAIISGGKGTADEKFAALEAAGVKTVRSLAEIGAALKALLK

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=287, Percent_Identity=66.5505226480836, Blast_Score=326, Evalue=1e-89,
Organism=Homo sapiens, GI38569423, Length=262, Percent_Identity=32.824427480916, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI38569421, Length=262, Percent_Identity=32.824427480916, Blast_Score=109, Evalue=3e-24,
Organism=Escherichia coli, GI1786949, Length=289, Percent_Identity=86.5051903114187, Blast_Score=505, Evalue=1e-144,
Organism=Caenorhabditis elegans, GI17550194, Length=288, Percent_Identity=64.5833333333333, Blast_Score=353, Evalue=8e-98,
Organism=Caenorhabditis elegans, GI17553126, Length=293, Percent_Identity=64.1638225255973, Blast_Score=343, Evalue=4e-95,
Organism=Caenorhabditis elegans, GI17551266, Length=256, Percent_Identity=28.90625, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17557344, Length=255, Percent_Identity=28.2352941176471, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6324716, Length=292, Percent_Identity=54.7945205479452, Blast_Score=296, Evalue=2e-81,
Organism=Drosophila melanogaster, GI21356559, Length=288, Percent_Identity=59.0277777777778, Blast_Score=343, Evalue=8e-95,
Organism=Drosophila melanogaster, GI28574296, Length=293, Percent_Identity=62.7986348122867, Blast_Score=340, Evalue=6e-94,
Organism=Drosophila melanogaster, GI281363477, Length=251, Percent_Identity=29.4820717131474, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI281363475, Length=251, Percent_Identity=29.4820717131474, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI281363473, Length=251, Percent_Identity=29.4820717131474, Blast_Score=99, Evalue=5e-21,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 29752; Mature: 29621

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILINKDTKVICQGFTGGQGTFHSEQALAYGTQLVGGVSPGKGGTTHLGLPVFNTVRDA
CEEEEECCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHH
VDATGATASVIYVPAPGCKDAILEAIDAGIQLVICITEGIPTLDMLQVKQRLNQTGVRMI
HHCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHCCCEEE
GPNCPGVITPEECKIGIMPGNIHKKGKIGIVSRSGTLTYEAVKQTTDEGFGQSTCVGIGG
CCCCCCCCCCCCCEEEEECCCCCCCCCEEEEECCCCEEHHHHHHHHHCCCCCCEEEECCC
DPIPGSNFIDILKLFQDDPQTEAIVMIGEIGGSAEEEAAAFIKDYVTKPVVSYIAGVTAP
CCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
KGKRMGHAGAIISGGKGTADEKFAALEAAGVKTVRSLAEIGAALKALLK
CCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
SILINKDTKVICQGFTGGQGTFHSEQALAYGTQLVGGVSPGKGGTTHLGLPVFNTVRDA
EEEEECCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEECCHHHHHHHHH
VDATGATASVIYVPAPGCKDAILEAIDAGIQLVICITEGIPTLDMLQVKQRLNQTGVRMI
HHCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHCCCEEE
GPNCPGVITPEECKIGIMPGNIHKKGKIGIVSRSGTLTYEAVKQTTDEGFGQSTCVGIGG
CCCCCCCCCCCCCEEEEECCCCCCCCCEEEEECCCCEEHHHHHHHHHCCCCCCEEEECCC
DPIPGSNFIDILKLFQDDPQTEAIVMIGEIGGSAEEEAAAFIKDYVTKPVVSYIAGVTAP
CCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
KGKRMGHAGAIISGGKGTADEKFAALEAAGVKTVRSLAEIGAALKALLK
CCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]