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The map label for this gene is sucC

Identifier: 15602145

GI number: 15602145

Start: 318911

End: 320077

Strand: Direct

Name: sucC

Synonym: PM0280

Alternate gene names: 15602145

Gene position: 318911-320077 (Clockwise)

Preceding gene: 15602144

Following gene: 15602146

Centisome position: 14.13

GC content: 44.99

Gene sequence:

>1167_bases
ATGAACCTACACGAGTATCAAGCGAAGCAAATTTTTGCAGAATATCAATTGCCAGTAGGCAAGGGTTATGCGTGTAAAAG
CGCAGATGAAGCCGCAGATGCAATAAAAAAACTCAATGGTGATGTTTGGGTCGCAAAATGCCAAGTTCACGCAGGTGGGC
GGGGTAAAGCTGGTGGTGTGAAATTGGTGCGTAACGAAGCCGAAGTGCGTGCTTTTGCTGACCAATGGTTAGGACAACGC
TTAGTGACTTTCCAAACGGACGTTAATGGGCAACCTGTTAATACTCTTTATGTGGAAGAAGGATCGAGCATTGCGCGTGA
GTTGTATTTAGGGGCAGTGCTTGATCGTGCATCACAACGTGTTGTGTTTATGGTGTCCACTGAAGGTGGGGTAAATATCG
AAGAAGTGGCGGAAAAAACACCGCACTTATTACATAAAATGGCGATTGATCCTCTAACGGGGGGGATGCCATACCAAGGG
CGTGAACTTGCGTTTAAACTGGGTTTAAAAGGTGATCAAATTAAACAATTTGCTCATATTTTCGTACAAATGGCAAAAAT
GTTTGTGGAAAAAGACTTGGCGCTGTTAGAAGTGAATCCCTTAGTGGTGACCAAAGAAGGTAATTTACTGTGTTTAGATG
CCAAAATCGTGGTCGATAGTAACGCCTTATACCGTCAGCCAGCATTAAAAGCGATGCAAGACCCAAGCCAAGAAGATCCA
CGTGAGGCGCTTGCAGAATCACACCAATTAAACTATGTAGCACTTGAGGGTAACATTGGTTGTATGGTGAATGGTGCAGG
CTTAGCCATGGGGACCATGGATATTATTAAATTACACGGGGGTCAACCAGCAAACTTCCTTGATGTGGGCGGTGGGGCGA
CCAAAGAGCGTGTGGCGGAAGCGTTCAAAATTATCTTATCGGATAGTGCAGTAAAAGCGGTATTAGTGAATATCTTTGGT
GGTATCGTGCGTTGCGATTTAATTGCAGAAGGGATCATTGCTGCCGTGAATGAAGTCGGCGTCAATGTGCCTGTGGTGGT
CCGTTTAGAAGGGAATAATGCGCCTTTAGGTCGTGAGATTTTAGCAAACAGTGGTGTGAATATTATTGCGGCAAATACTT
TAACGGATGCTGCGATTCAAGCTGTGAAAGCCGCGGAGGGAAAATAA

Upstream 100 bases:

>100_bases
ATGAATTTGGCACTTTGAATCAACACTTCTGCCATTTCTTACGATAAACAAACTCGCTTTGAATATGGGCTGAGAATATG
AAAATAAGGAACATAACGCT

Downstream 100 bases:

>100_bases
GATGTCTATTTTAATTAATAAAGATACCAAAGTGATTTGCCAAGGCTTTACTGGCGGACAAGGCACTTTCCACTCTGAAC
AAGCATTGGCTTACGGTACG

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MNLHEYQAKQIFAEYQLPVGKGYACKSADEAADAIKKLNGDVWVAKCQVHAGGRGKAGGVKLVRNEAEVRAFADQWLGQR
LVTFQTDVNGQPVNTLYVEEGSSIARELYLGAVLDRASQRVVFMVSTEGGVNIEEVAEKTPHLLHKMAIDPLTGGMPYQG
RELAFKLGLKGDQIKQFAHIFVQMAKMFVEKDLALLEVNPLVVTKEGNLLCLDAKIVVDSNALYRQPALKAMQDPSQEDP
REALAESHQLNYVALEGNIGCMVNGAGLAMGTMDIIKLHGGQPANFLDVGGGATKERVAEAFKIILSDSAVKAVLVNIFG
GIVRCDLIAEGIIAAVNEVGVNVPVVVRLEGNNAPLGREILANSGVNIIAANTLTDAAIQAVKAAEGK

Sequences:

>Translated_388_residues
MNLHEYQAKQIFAEYQLPVGKGYACKSADEAADAIKKLNGDVWVAKCQVHAGGRGKAGGVKLVRNEAEVRAFADQWLGQR
LVTFQTDVNGQPVNTLYVEEGSSIARELYLGAVLDRASQRVVFMVSTEGGVNIEEVAEKTPHLLHKMAIDPLTGGMPYQG
RELAFKLGLKGDQIKQFAHIFVQMAKMFVEKDLALLEVNPLVVTKEGNLLCLDAKIVVDSNALYRQPALKAMQDPSQEDP
REALAESHQLNYVALEGNIGCMVNGAGLAMGTMDIIKLHGGQPANFLDVGGGATKERVAEAFKIILSDSAVKAVLVNIFG
GIVRCDLIAEGIIAAVNEVGVNVPVVVRLEGNNAPLGREILANSGVNIIAANTLTDAAIQAVKAAEGK
>Mature_388_residues
MNLHEYQAKQIFAEYQLPVGKGYACKSADEAADAIKKLNGDVWVAKCQVHAGGRGKAGGVKLVRNEAEVRAFADQWLGQR
LVTFQTDVNGQPVNTLYVEEGSSIARELYLGAVLDRASQRVVFMVSTEGGVNIEEVAEKTPHLLHKMAIDPLTGGMPYQG
RELAFKLGLKGDQIKQFAHIFVQMAKMFVEKDLALLEVNPLVVTKEGNLLCLDAKIVVDSNALYRQPALKAMQDPSQEDP
REALAESHQLNYVALEGNIGCMVNGAGLAMGTMDIIKLHGGQPANFLDVGGGATKERVAEAFKIILSDSAVKAVLVNIFG
GIVRCDLIAEGIIAAVNEVGVNVPVVVRLEGNNAPLGREILANSGVNIIAANTLTDAAIQAVKAAEGK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI11321583, Length=393, Percent_Identity=46.0559796437659, Blast_Score=336, Evalue=3e-92,
Organism=Homo sapiens, GI157779135, Length=383, Percent_Identity=43.8642297650131, Blast_Score=300, Evalue=2e-81,
Organism=Homo sapiens, GI294862256, Length=358, Percent_Identity=44.1340782122905, Blast_Score=285, Evalue=5e-77,
Organism=Escherichia coli, GI1786948, Length=388, Percent_Identity=72.1649484536082, Blast_Score=561, Evalue=1e-161,
Organism=Caenorhabditis elegans, GI17539378, Length=393, Percent_Identity=42.4936386768448, Blast_Score=310, Evalue=8e-85,
Organism=Caenorhabditis elegans, GI17567829, Length=389, Percent_Identity=43.7017994858612, Blast_Score=309, Evalue=2e-84,
Organism=Saccharomyces cerevisiae, GI6321683, Length=393, Percent_Identity=40.9669211195929, Blast_Score=316, Evalue=5e-87,
Organism=Drosophila melanogaster, GI161078106, Length=393, Percent_Identity=44.2748091603053, Blast_Score=312, Evalue=3e-85,
Organism=Drosophila melanogaster, GI24645208, Length=393, Percent_Identity=44.2748091603053, Blast_Score=312, Evalue=3e-85,
Organism=Drosophila melanogaster, GI281361397, Length=394, Percent_Identity=44.4162436548223, Blast_Score=310, Evalue=1e-84,
Organism=Drosophila melanogaster, GI281361395, Length=394, Percent_Identity=44.4162436548223, Blast_Score=310, Evalue=1e-84,
Organism=Drosophila melanogaster, GI21356231, Length=395, Percent_Identity=44.3037974683544, Blast_Score=308, Evalue=4e-84,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_PASMU (Q9CNZ0)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245217.1
- ProteinModelPortal:   Q9CNZ0
- SMR:   Q9CNZ0
- GeneID:   1243627
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0280
- NMPDR:   fig|272843.1.peg.280
- HOGENOM:   HBG315432
- OMA:   ITEVNIN
- ProtClustDB:   PRK00696
- BioCyc:   PMUL272843:PM0280-MONOMER
- BRENDA:   6.2.1.5
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 41494; Mature: 41494

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLHEYQAKQIFAEYQLPVGKGYACKSADEAADAIKKLNGDVWVAKCQVHAGGRGKAGGV
CCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCE
KLVRNEAEVRAFADQWLGQRLVTFQTDVNGQPVNTLYVEEGSSIARELYLGAVLDRASQR
EEEECHHHHHHHHHHHHCCEEEEEEECCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCE
VVFMVSTEGGVNIEEVAEKTPHLLHKMAIDPLTGGMPYQGRELAFKLGLKGDQIKQFAHI
EEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHH
FVQMAKMFVEKDLALLEVNPLVVTKEGNLLCLDAKIVVDSNALYRQPALKAMQDPSQEDP
HHHHHHHHHHCCCEEEEECCEEEEECCCEEEEEEEEEECCCCHHHCHHHHHHCCCCCCCH
REALAESHQLNYVALEGNIGCMVNGAGLAMGTMDIIKLHGGQPANFLDVGGGATKERVAE
HHHHHHCCCCEEEEEECCCEEEEECCCCEECCEEEEEECCCCCCCEEECCCCCCHHHHHH
AFKIILSDSAVKAVLVNIFGGIVRCDLIAEGIIAAVNEVGVNVPVVVRLEGNNAPLGREI
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHH
LANSGVNIIAANTLTDAAIQAVKAAEGK
HHCCCCEEEEECCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNLHEYQAKQIFAEYQLPVGKGYACKSADEAADAIKKLNGDVWVAKCQVHAGGRGKAGGV
CCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCE
KLVRNEAEVRAFADQWLGQRLVTFQTDVNGQPVNTLYVEEGSSIARELYLGAVLDRASQR
EEEECHHHHHHHHHHHHCCEEEEEEECCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCE
VVFMVSTEGGVNIEEVAEKTPHLLHKMAIDPLTGGMPYQGRELAFKLGLKGDQIKQFAHI
EEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHH
FVQMAKMFVEKDLALLEVNPLVVTKEGNLLCLDAKIVVDSNALYRQPALKAMQDPSQEDP
HHHHHHHHHHCCCEEEEECCEEEEECCCEEEEEEEEEECCCCHHHCHHHHHHCCCCCCCH
REALAESHQLNYVALEGNIGCMVNGAGLAMGTMDIIKLHGGQPANFLDVGGGATKERVAE
HHHHHHCCCCEEEEEECCCEEEEECCCCEECCEEEEEECCCCCCCEEECCCCCCHHHHHH
AFKIILSDSAVKAVLVNIFGGIVRCDLIAEGIIAAVNEVGVNVPVVVRLEGNNAPLGREI
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHH
LANSGVNIIAANTLTDAAIQAVKAAEGK
HHCCCCEEEEECCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100