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The map label for this gene is lolA

Identifier: 15602121

GI number: 15602121

Start: 288070

End: 288687

Strand: Direct

Name: lolA

Synonym: PM0256

Alternate gene names: 15602121

Gene position: 288070-288687 (Clockwise)

Preceding gene: 15602120

Following gene: 15602122

Centisome position: 12.76

GC content: 39.32

Gene sequence:

>618_bases
ATGAATAACATGTTATTAAAAACCACCGCACTTTTGACCCTCTTTTTGAGCAGTGCAGCTTGGGCTGATGCAGCAAGCGA
ATTACAGCAACGTTTGAGCAAGGTGAATGTGTTGAGTGCTGATTATGCTCAAACAGTCAGTTCGTCAGACGGAAAAAATG
TTCAACAAGGCAGTGGGACATTAAAAATCAAGCGTCCAAATTTATTCCGAATGGATAATAAAACACCGCAAGAAAACCAG
ATTATTTCAGATGGGAAAACCTTGTGGTTTTATGATCCCTTTGTTGAGCAAGTGACAGCAAATTGGGTCAAAGATGCCGT
GAATAACACACCTTTTGTTTTGTTGACGAGTGACGATAGCAGCCACTGGGCACAATACAATGTGGAACAAAAGGCAGATA
CATTTACCCTCAAGCCAAAAGCAAAGCAGAGTAATATTAAGCAGTTTGATATTCGTATTGATAGTGAAGGGGTATTGCGT
AACTTCAGTACTATTGAAAAAGATGGTCAAACGAATTTGTATATTTTACGTAATATTACCAACCAACCTTTAGCCGATGG
TATATTCAAGTTTAGTGTGCCTAAAGGGGTAGAACTCGATGACCAACGCCAAAAATAG

Upstream 100 bases:

>100_bases
ATTATGGATCAACTCGAAGAACAGGGCATTGTTTCTGCGATGCAAAATGGCAAACGTGAAGTGCTTGCTAGACGTTCTTC
GGACTTTTAGGAAAGTAGAG

Downstream 100 bases:

>100_bases
TTAGAACAGTGATGTCGAATTTAAGTTTTGACTTTGCCCAACAGGCTTTTCAACCTTTAGCCGCCAGAATGCGTCCGACG
ACATTCGCTCAATATTGTGG

Product: outer-membrane lipoprotein carrier protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MNNMLLKTTALLTLFLSSAAWADAASELQQRLSKVNVLSADYAQTVSSSDGKNVQQGSGTLKIKRPNLFRMDNKTPQENQ
IISDGKTLWFYDPFVEQVTANWVKDAVNNTPFVLLTSDDSSHWAQYNVEQKADTFTLKPKAKQSNIKQFDIRIDSEGVLR
NFSTIEKDGQTNLYILRNITNQPLADGIFKFSVPKGVELDDQRQK

Sequences:

>Translated_205_residues
MNNMLLKTTALLTLFLSSAAWADAASELQQRLSKVNVLSADYAQTVSSSDGKNVQQGSGTLKIKRPNLFRMDNKTPQENQ
IISDGKTLWFYDPFVEQVTANWVKDAVNNTPFVLLTSDDSSHWAQYNVEQKADTFTLKPKAKQSNIKQFDIRIDSEGVLR
NFSTIEKDGQTNLYILRNITNQPLADGIFKFSVPKGVELDDQRQK
>Mature_205_residues
MNNMLLKTTALLTLFLSSAAWADAASELQQRLSKVNVLSADYAQTVSSSDGKNVQQGSGTLKIKRPNLFRMDNKTPQENQ
IISDGKTLWFYDPFVEQVTANWVKDAVNNTPFVLLTSDDSSHWAQYNVEQKADTFTLKPKAKQSNIKQFDIRIDSEGVLR
NFSTIEKDGQTNLYILRNITNQPLADGIFKFSVPKGVELDDQRQK

Specific function: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the l

COG id: COG2834

COG function: function code M; Outer membrane lipoprotein-sorting protein

Gene ontology:

Cell location: Periplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolA family

Homologues:

Organism=Escherichia coli, GI145693108, Length=197, Percent_Identity=47.7157360406091, Blast_Score=199, Evalue=9e-53,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): LOLA_PASMU (P57835)

Other databases:

- EMBL:   AE004439
- RefSeq:   NP_245193.1
- ProteinModelPortal:   P57835
- SMR:   P57835
- GeneID:   1243603
- GenomeReviews:   AE004439_GR
- KEGG:   pmu:PM0256
- NMPDR:   fig|272843.1.peg.256
- HOGENOM:   HBG688940
- OMA:   VDIDDQR
- ProtClustDB:   PRK00031
- BioCyc:   PMUL272843:PM0256-MONOMER
- HAMAP:   MF_00240
- InterPro:   IPR004564
- InterPro:   IPR018323
- TIGRFAMs:   TIGR00547

Pfam domain/function: PF03548 LolA

EC number: NA

Molecular weight: Translated: 23123; Mature: 23123

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNMLLKTTALLTLFLSSAAWADAASELQQRLSKVNVLSADYAQTVSSSDGKNVQQGSGT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCEECCCCE
LKIKRPNLFRMDNKTPQENQIISDGKTLWFYDPFVEQVTANWVKDAVNNTPFVLLTSDDS
EEEECCCEEECCCCCCCCCEEECCCCEEEEECHHHHHHHHHHHHHHHCCCCEEEEECCCC
SHWAQYNVEQKADTFTLKPKAKQSNIKQFDIRIDSEGVLRNFSTIEKDGQTNLYILRNIT
CCHHEECCCCCCCEEEECCCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCEEEEECCC
NQPLADGIFKFSVPKGVELDDQRQK
CCCCCCCEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MNNMLLKTTALLTLFLSSAAWADAASELQQRLSKVNVLSADYAQTVSSSDGKNVQQGSGT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCEECCCCE
LKIKRPNLFRMDNKTPQENQIISDGKTLWFYDPFVEQVTANWVKDAVNNTPFVLLTSDDS
EEEECCCEEECCCCCCCCCEEECCCCEEEEECHHHHHHHHHHHHHHHCCCCEEEEECCCC
SHWAQYNVEQKADTFTLKPKAKQSNIKQFDIRIDSEGVLRNFSTIEKDGQTNLYILRNIT
CCHHEECCCCCCCEEEECCCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCEEEEECCC
NQPLADGIFKFSVPKGVELDDQRQK
CCCCCCCEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100