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The map label for this gene is pmbA [H]

Identifier: 15601985

GI number: 15601985

Start: 146013

End: 147368

Strand: Direct

Name: pmbA [H]

Synonym: PM0120

Alternate gene names: 15601985

Gene position: 146013-147368 (Clockwise)

Preceding gene: 15601983

Following gene: 15601986

Centisome position: 6.47

GC content: 43.44

Gene sequence:

>1356_bases
ATGCAAAATACAGAAAAATCGACCGCACTTTTGAAACAACAAGAGCAAACATTGCGTGAAGCCGTGCGTTATGCTGTGGA
TTTGGCACAAAAAGCAGGGGCTACTGCGGAAGTAGCGGTGACAAAGGTCAGTGGATTGTCCGTTTCTACCCGTTTACAAG
AGATTGAAAATGTCGAATTTACTAACGATGGTGCGTTAGGGATTTCGGTTTATTTAGGAAATCAAAAAGGCAATGCCTCG
ACGTCGGATTTAAGCCCTGAGGCGATCAAAAACACTGTTGAAGCGGCAATATCCATTGCCAAATATGCGTCGCCAGATGA
GTGTGCGGGATTGGCGGATTATGACTTAATGGCATTTGATGCGCCTGATTTAGCCCTTTATCATGCAGCGGATATTGATG
TGGAAAAGGCGACGGCATTAGCATTGGAAACTGAGCAGGCGGCGTTAAGTTATGATAAACGTATTGTCAACAGTGAAGGT
TCTGCGTTTAATTCACATACTGGGGTGCGTGTTTATGGAAATACACACGGGATGTTACAAAGTTATTTATCCAGTCGCTA
TTCGTTATCTTGTTCTGTCATTGCTGGTGTAGAAGATCAGCTAGAACGGGATTATGAATATACGATTTCTCGTGACTTGA
ATCAGTTAGAAAGTGCGAGTTGGGTAGGCGAGCATTGTGCGAAGAAAACCCTGTCTCGTTTACAACCACAAAAAATGGCA
ACCCAGCAAGTGCCGGTCATTTTTTTGAATGATGTGGCAACCGGGCTTATTAGTCATTTAACCGCCGCGATTAGTGGGGG
GAGCTTATACCGTAAATCAAGTTTTCTGTTAGATCATTTAGGGAAACAAGTGCTACCCGATTGGTTCCACATTAGTGAAC
AACCGCATTTAATCGGACAACTCGCCTCTTCGCCTTTTGATAGTGAAGGCGTGCGCACTCAATGTCGTGAAATTATTCAG
CAAGGTACCTTACAAACTTATTTGTTGACCAGTTATAGTGGGAAAAAATTAGGCATGCGAAGCACAGGACATGCTGGAGG
CATTCATAACTGGTTAGTGAAGCCAAATACCACGGGCGGATTGACCACCTTATTACGCCAGATGGGAACCGGATTGCTGG
TAACTGATTTAATGGGGCAAGGGGTAAATTTAGTTACTGGTGATTATTCACGTGGCGCAGCCGGTTTCTGGGTAGAAAAT
GGCGAAATTCAATATCCTGTGGCAGAAATTACTATTGCGGGTCAATTGAAAGAGATGTTACGCAATATCGTTGCCGTTGG
TGATGATATTGAACATCGCTCGAATATCCAAACAGGATCAATTTTATTAGAGCATCTCAAAGTGTCTGGAAATTAA

Upstream 100 bases:

>100_bases
TGCCATACTCTTTCCTTTCATCTCATAAAAACAAGCGAACATTTTAGCATGAAAATCTAAAATAGGATAAAATGCCCAAA
ATTTGTTTGAAGGAATCAAT

Downstream 100 bases:

>100_bases
TTTTTGCAAATGATAATAATTCCTATTGACATGAGGTGATAATTTGCTAAGATAGCCACATCTGTTAGAGATAAAGGTGG
GAATGATAGAGTAGATCGTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MQNTEKSTALLKQQEQTLREAVRYAVDLAQKAGATAEVAVTKVSGLSVSTRLQEIENVEFTNDGALGISVYLGNQKGNAS
TSDLSPEAIKNTVEAAISIAKYASPDECAGLADYDLMAFDAPDLALYHAADIDVEKATALALETEQAALSYDKRIVNSEG
SAFNSHTGVRVYGNTHGMLQSYLSSRYSLSCSVIAGVEDQLERDYEYTISRDLNQLESASWVGEHCAKKTLSRLQPQKMA
TQQVPVIFLNDVATGLISHLTAAISGGSLYRKSSFLLDHLGKQVLPDWFHISEQPHLIGQLASSPFDSEGVRTQCREIIQ
QGTLQTYLLTSYSGKKLGMRSTGHAGGIHNWLVKPNTTGGLTTLLRQMGTGLLVTDLMGQGVNLVTGDYSRGAAGFWVEN
GEIQYPVAEITIAGQLKEMLRNIVAVGDDIEHRSNIQTGSILLEHLKVSGN

Sequences:

>Translated_451_residues
MQNTEKSTALLKQQEQTLREAVRYAVDLAQKAGATAEVAVTKVSGLSVSTRLQEIENVEFTNDGALGISVYLGNQKGNAS
TSDLSPEAIKNTVEAAISIAKYASPDECAGLADYDLMAFDAPDLALYHAADIDVEKATALALETEQAALSYDKRIVNSEG
SAFNSHTGVRVYGNTHGMLQSYLSSRYSLSCSVIAGVEDQLERDYEYTISRDLNQLESASWVGEHCAKKTLSRLQPQKMA
TQQVPVIFLNDVATGLISHLTAAISGGSLYRKSSFLLDHLGKQVLPDWFHISEQPHLIGQLASSPFDSEGVRTQCREIIQ
QGTLQTYLLTSYSGKKLGMRSTGHAGGIHNWLVKPNTTGGLTTLLRQMGTGLLVTDLMGQGVNLVTGDYSRGAAGFWVEN
GEIQYPVAEITIAGQLKEMLRNIVAVGDDIEHRSNIQTGSILLEHLKVSGN
>Mature_451_residues
MQNTEKSTALLKQQEQTLREAVRYAVDLAQKAGATAEVAVTKVSGLSVSTRLQEIENVEFTNDGALGISVYLGNQKGNAS
TSDLSPEAIKNTVEAAISIAKYASPDECAGLADYDLMAFDAPDLALYHAADIDVEKATALALETEQAALSYDKRIVNSEG
SAFNSHTGVRVYGNTHGMLQSYLSSRYSLSCSVIAGVEDQLERDYEYTISRDLNQLESASWVGEHCAKKTLSRLQPQKMA
TQQVPVIFLNDVATGLISHLTAAISGGSLYRKSSFLLDHLGKQVLPDWFHISEQPHLIGQLASSPFDSEGVRTQCREIIQ
QGTLQTYLLTSYSGKKLGMRSTGHAGGIHNWLVKPNTTGGLTTLLRQMGTGLLVTDLMGQGVNLVTGDYSRGAAGFWVEN
GEIQYPVAEITIAGQLKEMLRNIVAVGDDIEHRSNIQTGSILLEHLKVSGN

Specific function: May Facilitate The Secretion Of The Peptide Antibiotic Microcin B17 (Mccb17) By Completing Its Maturation. Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1790682, Length=447, Percent_Identity=61.2975391498881, Blast_Score=576, Evalue=1e-165,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 48771; Mature: 48771

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNTEKSTALLKQQEQTLREAVRYAVDLAQKAGATAEVAVTKVSGLSVSTRLQEIENVEF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHCCEE
TNDGALGISVYLGNQKGNASTSDLSPEAIKNTVEAAISIAKYASPDECAGLADYDLMAFD
CCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCEEEEC
APDLALYHAADIDVEKATALALETEQAALSYDKRIVNSEGSAFNSHTGVRVYGNTHGMLQ
CCCEEEEEECCCCHHHHHHHEEEHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCHHHHH
SYLSSRYSLSCSVIAGVEDQLERDYEYTISRDLNQLESASWVGEHCAKKTLSRLQPQKMA
HHHHHCCCEEEEEEECCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
TQQVPVIFLNDVATGLISHLTAAISGGSLYRKSSFLLDHLGKQVLPDWFHISEQPHLIGQ
HHCCCEEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHH
LASSPFDSEGVRTQCREIIQQGTLQTYLLTSYSGKKLGMRSTGHAGGIHNWLVKPNTTGG
HHCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEECCCCCCH
LTTLLRQMGTGLLVTDLMGQGVNLVTGDYSRGAAGFWVENGEIQYPVAEITIAGQLKEML
HHHHHHHHCCCEEEEHHHCCCCEEEECCCCCCCCEEEEECCEEECCHHHEEEHHHHHHHH
RNIVAVGDDIEHRSNIQTGSILLEHLKVSGN
HHHHHCCCCHHHHCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MQNTEKSTALLKQQEQTLREAVRYAVDLAQKAGATAEVAVTKVSGLSVSTRLQEIENVEF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHCCEE
TNDGALGISVYLGNQKGNASTSDLSPEAIKNTVEAAISIAKYASPDECAGLADYDLMAFD
CCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCEEEEC
APDLALYHAADIDVEKATALALETEQAALSYDKRIVNSEGSAFNSHTGVRVYGNTHGMLQ
CCCEEEEEECCCCHHHHHHHEEEHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCHHHHH
SYLSSRYSLSCSVIAGVEDQLERDYEYTISRDLNQLESASWVGEHCAKKTLSRLQPQKMA
HHHHHCCCEEEEEEECCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
TQQVPVIFLNDVATGLISHLTAAISGGSLYRKSSFLLDHLGKQVLPDWFHISEQPHLIGQ
HHCCCEEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHH
LASSPFDSEGVRTQCREIIQQGTLQTYLLTSYSGKKLGMRSTGHAGGIHNWLVKPNTTGG
HHCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEECCCCCCH
LTTLLRQMGTGLLVTDLMGQGVNLVTGDYSRGAAGFWVENGEIQYPVAEITIAGQLKEML
HHHHHHHHCCCEEEEHHHCCCCEEEECCCCCCCCEEEEECCEEECCHHHEEEHHHHHHHH
RNIVAVGDDIEHRSNIQTGSILLEHLKVSGN
HHHHHCCCCHHHHCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]