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The map label for this gene is focA [H]

Identifier: 15601939

GI number: 15601939

Start: 99486

End: 100337

Strand: Direct

Name: focA [H]

Synonym: PM0074

Alternate gene names: 15601939

Gene position: 99486-100337 (Clockwise)

Preceding gene: 15601934

Following gene: 15601940

Centisome position: 4.41

GC content: 42.96

Gene sequence:

>852_bases
ATGAAATCAGAAGAATCAACGTCAACCTGTATGGTGTCACCCACAAAGATGGCACAGATTGGCGAAGATGTCGGTGTTTA
TAAAGCCACAAAAAAACAAATCTACTCTTTCTTTTCTGCTATTCCAGCAGGGGCATTTATTGCCATTGCATTCGTTTTCT
ACGCAACCACACAAACCGGTAATGGTGATGCACCATGGGGACTCACAAAATTAGTCGGTGGTATTGTTTTCTCCCTTGGG
GTGATTATGGTGGTGGTGTGCGGTTCTGAACTTTTTACTTCATCAACGATGACTGCAGTTGCGCGAGTCAGTGGTCGAAT
CTCTACTTTCCAAATGTTGCGCAACTGGCTCGTGGTGTACGGAGGCAACTTTGTCGGCGCACTTTTCATTGTGTTGCTTA
CTTGGTTTGCAGGGCAAATTATGGCTGCCAACGGGCAATGGGGATTAACCATTTTAAAAACAGCCCAACATAAAATTCAT
CACACTTGGACAGAAGCCTTTGCATTGGGTATTTTTTGTAACATTATGGTGTGTATTGCGGTATGGATGACTTATGCCGG
CAAAACCTTATTAGATAAAGCGGTGATCATGATTTTGCCGATTTCGATGTTTGTGGCATCAGGCTTTGAGCATAGTGTGG
CAAATATGTTTATGATCCCAATGGGGATGATGATCGCGCATTTTGCTTCCCCTGAATTTTGGCAAGCTGTGAGTTTAAAT
CCCGCGCAATTTGCTGATTTAGATATGTATCATTTTGTAGTAAAAAATTTAATTCCCGTGACCTTAGGGAATATTGTTGG
TGGCGCCCTCTGTGTCGCATTAACACAGTGGTACATTAACCGCCCACATTAA

Upstream 100 bases:

>100_bases
ATTAACAAAAATTATAAAAAATAAAATTTTTTTAAATTATTGATTTATGTGACTCATCGTCATTAGGCATTATACGATAT
TCATGTAAGGGGATTTAAGG

Downstream 100 bases:

>100_bases
GCAGTTTAGGTGTAAAAGTAACAATGTTACTTTTATGTAAGCGATGACAAGATTTATTTTCATTAATTAATAGAAGGTAT
TGAGTATGAGTCAATTAAAT

Product: hypothetical protein

Products: formate [Periplasm]; formate [Cytoplasm] [C]

Alternate protein names: Formate channel [H]

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MKSEESTSTCMVSPTKMAQIGEDVGVYKATKKQIYSFFSAIPAGAFIAIAFVFYATTQTGNGDAPWGLTKLVGGIVFSLG
VIMVVVCGSELFTSSTMTAVARVSGRISTFQMLRNWLVVYGGNFVGALFIVLLTWFAGQIMAANGQWGLTILKTAQHKIH
HTWTEAFALGIFCNIMVCIAVWMTYAGKTLLDKAVIMILPISMFVASGFEHSVANMFMIPMGMMIAHFASPEFWQAVSLN
PAQFADLDMYHFVVKNLIPVTLGNIVGGALCVALTQWYINRPH

Sequences:

>Translated_283_residues
MKSEESTSTCMVSPTKMAQIGEDVGVYKATKKQIYSFFSAIPAGAFIAIAFVFYATTQTGNGDAPWGLTKLVGGIVFSLG
VIMVVVCGSELFTSSTMTAVARVSGRISTFQMLRNWLVVYGGNFVGALFIVLLTWFAGQIMAANGQWGLTILKTAQHKIH
HTWTEAFALGIFCNIMVCIAVWMTYAGKTLLDKAVIMILPISMFVASGFEHSVANMFMIPMGMMIAHFASPEFWQAVSLN
PAQFADLDMYHFVVKNLIPVTLGNIVGGALCVALTQWYINRPH
>Mature_283_residues
MKSEESTSTCMVSPTKMAQIGEDVGVYKATKKQIYSFFSAIPAGAFIAIAFVFYATTQTGNGDAPWGLTKLVGGIVFSLG
VIMVVVCGSELFTSSTMTAVARVSGRISTFQMLRNWLVVYGGNFVGALFIVLLTWFAGQIMAANGQWGLTILKTAQHKIH
HTWTEAFALGIFCNIMVCIAVWMTYAGKTLLDKAVIMILPISMFVASGFEHSVANMFMIPMGMMIAHFASPEFWQAVSLN
PAQFADLDMYHFVVKNLIPVTLGNIVGGALCVALTQWYINRPH

Specific function: Involved in the bidirectional transport of formate [H]

COG id: COG2116

COG function: function code P; Formate/nitrite family of transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FNT transporter (TC 2.A.44) family [H]

Homologues:

Organism=Escherichia coli, GI1787132, Length=279, Percent_Identity=58.4229390681004, Blast_Score=343, Evalue=9e-96,
Organism=Escherichia coli, GI1788837, Length=261, Percent_Identity=47.5095785440613, Blast_Score=249, Evalue=1e-67,
Organism=Escherichia coli, GI87082249, Length=288, Percent_Identity=27.4305555555556, Blast_Score=76, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6321779, Length=216, Percent_Identity=26.3888888888889, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000292 [H]

Pfam domain/function: PF01226 Form_Nir_trans [H]

EC number: NA

Molecular weight: Translated: 30871; Mature: 30871

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: PS01005 FORMATE_NITRITE_TP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
6.0 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
6.0 %Met     (Mature Protein)
7.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSEESTSTCMVSPTKMAQIGEDVGVYKATKKQIYSFFSAIPAGAFIAIAFVFYATTQTG
CCCCCCCCEEEECHHHHHHHCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCC
NGDAPWGLTKLVGGIVFSLGVIMVVVCGSELFTSSTMTAVARVSGRISTFQMLRNWLVVY
CCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
GGNFVGALFIVLLTWFAGQIMAANGQWGLTILKTAQHKIHHTWTEAFALGIFCNIMVCIA
CCCHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VWMTYAGKTLLDKAVIMILPISMFVASGFEHSVANMFMIPMGMMIAHFASPEFWQAVSLN
HHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCC
PAQFADLDMYHFVVKNLIPVTLGNIVGGALCVALTQWYINRPH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKSEESTSTCMVSPTKMAQIGEDVGVYKATKKQIYSFFSAIPAGAFIAIAFVFYATTQTG
CCCCCCCCEEEECHHHHHHHCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCC
NGDAPWGLTKLVGGIVFSLGVIMVVVCGSELFTSSTMTAVARVSGRISTFQMLRNWLVVY
CCCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
GGNFVGALFIVLLTWFAGQIMAANGQWGLTILKTAQHKIHHTWTEAFALGIFCNIMVCIA
CCCHHHHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VWMTYAGKTLLDKAVIMILPISMFVASGFEHSVANMFMIPMGMMIAHFASPEFWQAVSLN
HHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCC
PAQFADLDMYHFVVKNLIPVTLGNIVGGALCVALTQWYINRPH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: formate [Cytoplasm]; formate [Periplasm] [C]

Specific reaction: formate [Cytoplasm] = formate [Periplasm] formate [Periplasm] = formate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]