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The map label for this gene is recG

Identifier: 15674226

GI number: 15674226

Start: 2329913

End: 2331913

Strand: Reverse

Name: recG

Synonym: L0262

Alternate gene names: 15674226

Gene position: 2331913-2329913 (Counterclockwise)

Preceding gene: 15674227

Following gene: 15674225

Centisome position: 98.58

GC content: 37.88

Gene sequence:

>2001_bases
ATGAAATTAACAGATTCAGTGCAATTTTTAAAAGGTGTGGGACCGAAATCTGTGGAAAATTTCCATAAGTTAGGAATTTT
CACGGTTCAAGATTTATTGCTTTATTTCCCTTTTCGTTATGAAGATTTCGCAAGTCGTTCGGTTTTTGAACTTGTTGACG
GAGAAAAAGCAACAATTATTGGAACGGTAGTGACACCAGCTAATGTCCAGTATTACGGATTTAAACGTAATCGACTTTCA
TTTAAAATTAAAGAAGGTGAGGCCGTGGTTGCTGTCAGCTTTTTTAATCAACCTTATTTGGCTGACAAAGTGGAAGTTGG
TAAGGAAATTGCAGTTTACGGAAAATGGGAGCAGGCAAAGCAACAACTGATGGGGATGAAGGTTGTGGCTCAGGTGGACG
ATGGCTTAGAACCTGTTTATCATTTGGCAGCGGGTATGAAACAAAGTCAATTGGTCAAAGTAATTCATCAGGTTTTTGAA
TCAGACCTTCTATCAGAATTACCTGAGAACTTACCAGAATTTTTGATTAAAAAATATCGTCTGATGAACCGGCAAGAAGC
CGTTTTGGCTATGCATTTTCCTGAAGATATGGAAGCTCATAAGCAGGCTTTACGTCGTGTAAAATTTGAAGAATTATTCA
TGTTTCAGTTGAAATTACAGGCCTTAAAAAATAAAGAAAAATCAGGCCGAGCAGGATTAGAAGTTGTTTTTGAGCAAGGA
GAAATTGATCAGAAGATTTCTGAATTACCTTTTGAACTGACAGGTGCTCAATTAAGCGCTTTGTCAGAGATTCTGACGGA
TATGAAATCTCCTTATCACATGAATCGACTTTTGCAAGGTGATGTGGGTTCTGGTAAAACAGTTGTTGCTTCCCTTGCCA
TGTACGCGGCTTGTTTGGCGAATTTTCAAGCAGCAATTATGGTACCAACGGAAATCCTTGCCCGTCAGCATTTTGCAAAC
TTGAAAGCTCTTTTTCCAGAATTGCAAATTTCACTTTTGGTTTCGGGTTTGAAAGTGGCAGAGCGCCGCGAGATTTTGGC
TGATTTAGTTAGTGGTCATACACATATGGTAGTTGGAACTCATGCGCTAATTCAAGAAGGGGTTAATTTTTATAATTTGG
GTTTGGTGATTACAGACGAACAACACCGTTTCGGAGTCAATCAACGAAAAATTTTACGAGAAAAAGGGCAAAATCCAGAT
GTTCTAATGATGACAGCTACACCCATTCCAAGAACGCTTGCGATTACGGCTTTTGGGGATATGGATGTTTCAATTATTGA
TGAACTACCCAAGGGACGTCAACCCATTACTACAAGGTGGGTCAAACATGAACAATTTTCCGAAGTTTTAAGTTGGATAA
AAGCAGAGGTTGCTAAAGATTCACAGGTTTATTTTATTTCACCTTTAATTGAGGAAAGTGAAACGTTGGACCTGAAAAAC
GCAGAAGCTCTTTTTGCGGAATTAAATGAATACTTTGGATTATTTGCCAAAATTGGTCTTTTACATGGAAAAATGAAAAA
TGATGAAAAAGACCAAATCATGCAAGAATTTAAGGCTAAAAAATTAGATATTTTGGTTTCAACAACAGTGATTGAAGTGG
GAGTTGACGTTCCTAATGCTACCATTATGGTGATTATGGATGCTGACCGCTTTGGACTTTCGCAGCTTCACCAATTGCGT
GGTCGTGTTGGTCGGGGAACAAAAAAATCTTATGCCATTTTAGTAGCAAATCCTAAGTCCGATTCAGGAAAACAACGGAT
GAAAATTATGACAGAAACACAAAATGGTTTTATTTTAGCCGAAGAAGATTTGAAAATGCGTGGTTCTGGAGAGATTTTTG
GACTTCGTCAGTCAGGACTTCCAGAATTTATTGCGGCTGATTTAGTCAATGATTATAATATTTTAGAAGTGGCTAGAAAA
GAAGCAGTTGAAATTTTTAAAAATGCAGATGAGTTTCCTGATTTGATTGCTCAAGTTAATGTTGACGGGGGCTTTGATTG
A

Upstream 100 bases:

>100_bases
ACAGAGCTTTCTGTCAGTAAATTTTGCTGATAAAATCTCTGTCAGCAAATTATATTTGATTTTTGAAGCATTTAACCTTA
TATATTGGTATAATAAAAGT

Downstream 100 bases:

>100_bases
TGAGTAAAATGGATAATGAAAAATTAGACCACTTGATTTTAGAAACGTGGACAGATTTTATTGACTTAAAAAATAAGGCT
GAGCTGTCAGAAGTTTTGAT

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 666; Mature: 666

Protein sequence:

>666_residues
MKLTDSVQFLKGVGPKSVENFHKLGIFTVQDLLLYFPFRYEDFASRSVFELVDGEKATIIGTVVTPANVQYYGFKRNRLS
FKIKEGEAVVAVSFFNQPYLADKVEVGKEIAVYGKWEQAKQQLMGMKVVAQVDDGLEPVYHLAAGMKQSQLVKVIHQVFE
SDLLSELPENLPEFLIKKYRLMNRQEAVLAMHFPEDMEAHKQALRRVKFEELFMFQLKLQALKNKEKSGRAGLEVVFEQG
EIDQKISELPFELTGAQLSALSEILTDMKSPYHMNRLLQGDVGSGKTVVASLAMYAACLANFQAAIMVPTEILARQHFAN
LKALFPELQISLLVSGLKVAERREILADLVSGHTHMVVGTHALIQEGVNFYNLGLVITDEQHRFGVNQRKILREKGQNPD
VLMMTATPIPRTLAITAFGDMDVSIIDELPKGRQPITTRWVKHEQFSEVLSWIKAEVAKDSQVYFISPLIEESETLDLKN
AEALFAELNEYFGLFAKIGLLHGKMKNDEKDQIMQEFKAKKLDILVSTTVIEVGVDVPNATIMVIMDADRFGLSQLHQLR
GRVGRGTKKSYAILVANPKSDSGKQRMKIMTETQNGFILAEEDLKMRGSGEIFGLRQSGLPEFIAADLVNDYNILEVARK
EAVEIFKNADEFPDLIAQVNVDGGFD

Sequences:

>Translated_666_residues
MKLTDSVQFLKGVGPKSVENFHKLGIFTVQDLLLYFPFRYEDFASRSVFELVDGEKATIIGTVVTPANVQYYGFKRNRLS
FKIKEGEAVVAVSFFNQPYLADKVEVGKEIAVYGKWEQAKQQLMGMKVVAQVDDGLEPVYHLAAGMKQSQLVKVIHQVFE
SDLLSELPENLPEFLIKKYRLMNRQEAVLAMHFPEDMEAHKQALRRVKFEELFMFQLKLQALKNKEKSGRAGLEVVFEQG
EIDQKISELPFELTGAQLSALSEILTDMKSPYHMNRLLQGDVGSGKTVVASLAMYAACLANFQAAIMVPTEILARQHFAN
LKALFPELQISLLVSGLKVAERREILADLVSGHTHMVVGTHALIQEGVNFYNLGLVITDEQHRFGVNQRKILREKGQNPD
VLMMTATPIPRTLAITAFGDMDVSIIDELPKGRQPITTRWVKHEQFSEVLSWIKAEVAKDSQVYFISPLIEESETLDLKN
AEALFAELNEYFGLFAKIGLLHGKMKNDEKDQIMQEFKAKKLDILVSTTVIEVGVDVPNATIMVIMDADRFGLSQLHQLR
GRVGRGTKKSYAILVANPKSDSGKQRMKIMTETQNGFILAEEDLKMRGSGEIFGLRQSGLPEFIAADLVNDYNILEVARK
EAVEIFKNADEFPDLIAQVNVDGGFD
>Mature_666_residues
MKLTDSVQFLKGVGPKSVENFHKLGIFTVQDLLLYFPFRYEDFASRSVFELVDGEKATIIGTVVTPANVQYYGFKRNRLS
FKIKEGEAVVAVSFFNQPYLADKVEVGKEIAVYGKWEQAKQQLMGMKVVAQVDDGLEPVYHLAAGMKQSQLVKVIHQVFE
SDLLSELPENLPEFLIKKYRLMNRQEAVLAMHFPEDMEAHKQALRRVKFEELFMFQLKLQALKNKEKSGRAGLEVVFEQG
EIDQKISELPFELTGAQLSALSEILTDMKSPYHMNRLLQGDVGSGKTVVASLAMYAACLANFQAAIMVPTEILARQHFAN
LKALFPELQISLLVSGLKVAERREILADLVSGHTHMVVGTHALIQEGVNFYNLGLVITDEQHRFGVNQRKILREKGQNPD
VLMMTATPIPRTLAITAFGDMDVSIIDELPKGRQPITTRWVKHEQFSEVLSWIKAEVAKDSQVYFISPLIEESETLDLKN
AEALFAELNEYFGLFAKIGLLHGKMKNDEKDQIMQEFKAKKLDILVSTTVIEVGVDVPNATIMVIMDADRFGLSQLHQLR
GRVGRGTKKSYAILVANPKSDSGKQRMKIMTETQNGFILAEEDLKMRGSGEIFGLRQSGLPEFIAADLVNDYNILEVARK
EAVEIFKNADEFPDLIAQVNVDGGFD

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=675, Percent_Identity=38.5185185185185, Blast_Score=410, Evalue=1e-115,
Organism=Escherichia coli, GI1787357, Length=412, Percent_Identity=37.378640776699, Blast_Score=261, Evalue=8e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 74831; Mature: 74831

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTDSVQFLKGVGPKSVENFHKLGIFTVQDLLLYFPFRYEDFASRSVFELVDGEKATII
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHCCCCEEEE
GTVVTPANVQYYGFKRNRLSFKIKEGEAVVAVSFFNQPYLADKVEVGKEIAVYGKWEQAK
EEEECCCCEEEEEEECCCEEEEEECCCEEEEEEECCCCCCCHHHHCCCEEEEECCHHHHH
QQLMGMKVVAQVDDGLEPVYHLAAGMKQSQLVKVIHQVFESDLLSELPENLPEFLIKKYR
HHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMNRQEAVLAMHFPEDMEAHKQALRRVKFEELFMFQLKLQALKNKEKSGRAGLEVVFEQG
HCCCCCEEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECC
EIDQKISELPFELTGAQLSALSEILTDMKSPYHMNRLLQGDVGSGKTVVASLAMYAACLA
CHHHHHHHCCCEECCHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
NFQAAIMVPTEILARQHFANLKALFPELQISLLVSGLKVAERREILADLVSGHTHMVVGT
CCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEH
HALIQEGVNFYNLGLVITDEQHRFGVNQRKILREKGQNPDVLMMTATPIPRTLAITAFGD
HHHHHCCCCEEEEEEEEECCHHHCCCCHHHHHHHCCCCCCEEEEECCCCCCEEEEEEECC
MDVSIIDELPKGRQPITTRWVKHEQFSEVLSWIKAEVAKDSQVYFISPLIEESETLDLKN
CCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHCCCCCCCCCH
AEALFAELNEYFGLFAKIGLLHGKMKNDEKDQIMQEFKAKKLDILVSTTVIEVGVDVPNA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEEEEEEEEEEECCCCCC
TIMVIMDADRFGLSQLHQLRGRVGRGTKKSYAILVANPKSDSGKQRMKIMTETQNGFILA
EEEEEECCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHEEEEECCCCEEEE
EEDLKMRGSGEIFGLRQSGLPEFIAADLVNDYNILEVARKEAVEIFKNADEFPDLIAQVN
CCCCCCCCCCCEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHEEEC
VDGGFD
CCCCCC
>Mature Secondary Structure
MKLTDSVQFLKGVGPKSVENFHKLGIFTVQDLLLYFPFRYEDFASRSVFELVDGEKATII
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHCCCCEEEE
GTVVTPANVQYYGFKRNRLSFKIKEGEAVVAVSFFNQPYLADKVEVGKEIAVYGKWEQAK
EEEECCCCEEEEEEECCCEEEEEECCCEEEEEEECCCCCCCHHHHCCCEEEEECCHHHHH
QQLMGMKVVAQVDDGLEPVYHLAAGMKQSQLVKVIHQVFESDLLSELPENLPEFLIKKYR
HHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LMNRQEAVLAMHFPEDMEAHKQALRRVKFEELFMFQLKLQALKNKEKSGRAGLEVVFEQG
HCCCCCEEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECC
EIDQKISELPFELTGAQLSALSEILTDMKSPYHMNRLLQGDVGSGKTVVASLAMYAACLA
CHHHHHHHCCCEECCHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
NFQAAIMVPTEILARQHFANLKALFPELQISLLVSGLKVAERREILADLVSGHTHMVVGT
CCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEH
HALIQEGVNFYNLGLVITDEQHRFGVNQRKILREKGQNPDVLMMTATPIPRTLAITAFGD
HHHHHCCCCEEEEEEEEECCHHHCCCCHHHHHHHCCCCCCEEEEECCCCCCEEEEEEECC
MDVSIIDELPKGRQPITTRWVKHEQFSEVLSWIKAEVAKDSQVYFISPLIEESETLDLKN
CCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHCCCCCCCCCH
AEALFAELNEYFGLFAKIGLLHGKMKNDEKDQIMQEFKAKKLDILVSTTVIEVGVDVPNA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEEEEEEEEEEECCCCCC
TIMVIMDADRFGLSQLHQLRGRVGRGTKKSYAILVANPKSDSGKQRMKIMTETQNGFILA
EEEEEECCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHEEEEECCCCEEEE
EEDLKMRGSGEIFGLRQSGLPEFIAADLVNDYNILEVARKEAVEIFKNADEFPDLIAQVN
CCCCCCCCCCCEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHEEEC
VDGGFD
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8830261; 11463916 [H]