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The map label for this gene is rpiA

Identifier: 15674215

GI number: 15674215

Start: 2316936

End: 2317610

Strand: Reverse

Name: rpiA

Synonym: L0045

Alternate gene names: 15674215

Gene position: 2317610-2316936 (Counterclockwise)

Preceding gene: 15674216

Following gene: 15674213

Centisome position: 97.97

GC content: 36.59

Gene sequence:

>675_bases
ATGGATAATTTAAAAAAACAAGTCGGCATAAAAGCTGCTGAATTTGTTAAATCGGGAATGGTCGTTGGTTTAGGAACTGG
GTCAACAGCAGCCTATTTTGTCGAAGAATTGGGTCGAAGAATTGCCGAAGAACAATTGGAAATTACGGGTGTAACAACGT
CCAATGTAACAAGTAGCCAAGCCAGAGCTCTTGGAATTCCTTTAGCCTCTATTGACGAAGTAGATTATGTTGATTTAACA
GTTGATGGCGCAGATGAAATTGATTCTTCACTAAATGGTATTAAAGGTGGTGGAGCAGCACTTCTAATGGAAAAAATTGT
TGCAACCTACTCAAAAGACTATATTTGGATTGTTGATGAAAGTAAATTATCAGAAAATCTAGGATCCTTTAAAATTCCTG
TAGAAGTTATTCCTTATGGCTCACAACAAGTTTTTAAAAAATTCGAAGCGGCTGGCTATGCTCCAACTTGGCGTCTAAAT
GAGGAAAACGAGAGATTGATAACGGATATGCATCACTTTATTATTGACCTTCATATCTCTCAAATTAAAGAACCAGAAAA
ACTTGCTGAAGAGCTTGATTTAATGGGTGGAGTTGTTGAACACGGCCTCTTTAATAACATGGTTAAAAAAGTGATTGTTG
CTGGCAACGAAGGCGTAAGAATAATAAATAAGTAA

Upstream 100 bases:

>100_bases
AAGAATATATTAGTTAATATAAACAGATAAAAAAGCTACTTTAGGTAGCTTTTTTGTTATAATTAGGTCAGCATGATATC
AAAGTATTCAAGGAGGTAAA

Downstream 100 bases:

>100_bases
ATAAAAAATCGTCAATCAGACGATTTTTTATTTCTTTAACCACTCTTGAACTCCCCATTTATGAGAGCCACGTTTGAGTT
TACTAATAGCTGTTTCTGGG

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MDNLKKQVGIKAAEFVKSGMVVGLGTGSTAAYFVEELGRRIAEEQLEITGVTTSNVTSSQARALGIPLASIDEVDYVDLT
VDGADEIDSSLNGIKGGGAALLMEKIVATYSKDYIWIVDESKLSENLGSFKIPVEVIPYGSQQVFKKFEAAGYAPTWRLN
EENERLITDMHHFIIDLHISQIKEPEKLAEELDLMGGVVEHGLFNNMVKKVIVAGNEGVRIINK

Sequences:

>Translated_224_residues
MDNLKKQVGIKAAEFVKSGMVVGLGTGSTAAYFVEELGRRIAEEQLEITGVTTSNVTSSQARALGIPLASIDEVDYVDLT
VDGADEIDSSLNGIKGGGAALLMEKIVATYSKDYIWIVDESKLSENLGSFKIPVEVIPYGSQQVFKKFEAAGYAPTWRLN
EENERLITDMHHFIIDLHISQIKEPEKLAEELDLMGGVVEHGLFNNMVKKVIVAGNEGVRIINK
>Mature_224_residues
MDNLKKQVGIKAAEFVKSGMVVGLGTGSTAAYFVEELGRRIAEEQLEITGVTTSNVTSSQARALGIPLASIDEVDYVDLT
VDGADEIDSSLNGIKGGGAALLMEKIVATYSKDYIWIVDESKLSENLGSFKIPVEVIPYGSQQVFKKFEAAGYAPTWRLN
EENERLITDMHHFIIDLHISQIKEPEKLAEELDLMGGVVEHGLFNNMVKKVIVAGNEGVRIINK

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=226, Percent_Identity=35.8407079646018, Blast_Score=117, Evalue=6e-27,
Organism=Escherichia coli, GI1789280, Length=224, Percent_Identity=39.2857142857143, Blast_Score=146, Evalue=8e-37,
Organism=Caenorhabditis elegans, GI17551758, Length=227, Percent_Identity=32.15859030837, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6324669, Length=211, Percent_Identity=32.2274881516588, Blast_Score=103, Evalue=1e-23,
Organism=Drosophila melanogaster, GI281364072, Length=216, Percent_Identity=32.4074074074074, Blast_Score=92, Evalue=3e-19,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_LACLA (Q9CDI7)

Other databases:

- EMBL:   AE005176
- PIR:   A86904
- RefSeq:   NP_268390.1
- ProteinModelPortal:   Q9CDI7
- SMR:   Q9CDI7
- GeneID:   1115911
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L0045
- NMPDR:   fig|272623.1.peg.2288
- HOGENOM:   HBG515603
- OMA:   MVVIADA
- ProtClustDB:   PRK00702
- BioCyc:   LLAC272623:L0045-MONOMER
- BRENDA:   5.3.1.6
- HAMAP:   MF_00170
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 24472; Mature: 24472

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNLKKQVGIKAAEFVKSGMVVGLGTGSTAAYFVEELGRRIAEEQLEITGVTTSNVTSSQ
CCCHHHHHCCHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHH
ARALGIPLASIDEVDYVDLTVDGADEIDSSLNGIKGGGAALLMEKIVATYSKDYIWIVDE
HHHHCCCCCCCCCCCEEEEEECCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEEEC
SKLSENLGSFKIPVEVIPYGSQQVFKKFEAAGYAPTWRLNEENERLITDMHHFIIDLHIS
HHHHHCCCCEECCEEEECCCCHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHH
QIKEPEKLAEELDLMGGVVEHGLFNNMVKKVIVAGNEGVRIINK
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
>Mature Secondary Structure
MDNLKKQVGIKAAEFVKSGMVVGLGTGSTAAYFVEELGRRIAEEQLEITGVTTSNVTSSQ
CCCHHHHHCCHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCCCHH
ARALGIPLASIDEVDYVDLTVDGADEIDSSLNGIKGGGAALLMEKIVATYSKDYIWIVDE
HHHHCCCCCCCCCCCEEEEEECCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEEEEC
SKLSENLGSFKIPVEVIPYGSQQVFKKFEAAGYAPTWRLNEENERLITDMHHFIIDLHIS
HHHHHCCCCEECCEEEECCCCHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHHHHHHHH
QIKEPEKLAEELDLMGGVVEHGLFNNMVKKVIVAGNEGVRIINK
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471