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The map label for this gene is arcD2

Identifier: 15674013

GI number: 15674013

Start: 2106337

End: 2107830

Strand: Reverse

Name: arcD2

Synonym: L0111

Alternate gene names: 15674013

Gene position: 2107830-2106337 (Counterclockwise)

Preceding gene: 15674014

Following gene: 15674012

Centisome position: 89.1

GC content: 38.22

Gene sequence:

>1494_bases
ATGGAAAACAAGAAAACAAAAGGGATTAGCCTTTTTGCACTATTAGCAATTATTATTTCTGGAGCAATTGGAGGTGGAGT
CTTCAATCTTGCTAATGACCTCGCCAATGGTTCAACACCCGGTGGAGTCATGATTTCATGGCTCTTTATCGGTTTTGGGA
TTTTCATGCTTGTCTTGAGTTTTAATCGACTGATTACAATTAGACCCAAACTTTCGGGAGTCTCTGATTATGCTCGAGAA
GGGTTTGGAGACTTTATCGGTTTTCTATCAGGATGGGGTTACTGGATTTCAGCTTGGACTGGAACAATTGGTTTTGCAGT
TTTAATGATGACATCTGCTGACTATTTCTTCCCTAGCAAATTTGCTAATTCCAATGGTTCGTTGACTGTTTTATCAGTAA
TTATTGTTTCAATAATCTCATGGATATTAATGTTTCTAGTTGACCGAGGAGTAGAAACTGCCGCCCTTGTAAATGCGGTT
GTTATGATTGCAAAGCTCATTCCTTTAGTTGTATTTTCAATCACAGGGATTATCCTATTTAAAGCTGACGTATTCACTCA
ACATTTTTGGCAAACTTTCACAAGCAATCTAGCTGCGGATGGGTCAGTCAAAAGCCTAGTTTGGCATGCGATGACTGCTG
GTGGACTCCTTGATCAAATTAAAGGCTCGCTGATGGTCATGGTCTGGGTATTTGTAGGGATTGAAGGCGCAGCGATGATG
GGAAATCGGGCAAAGAAAAAATCGGATACAGCTAAAGCGACAATTATTGGTCTAGCAGTTTTGCTTGTCATTTATGTCCT
TTTATCATTACTTCCTTATGGTTATATGGACCAGGCAAGTTTGGCAAATGTTAAAGCACCAGGCTTAGTTTATATTCTTA
ACGAGATGGTTGGTGGCTGGGGCGGAAGTCTGATGGCAATTGGACTAATGATTTCCTTATTAGGAGCTTGGCTTTCGTGG
ACAATGTTACCAGTTGAGGCGACACAACAATTGGCAGAGAAAAAACTATTGCCAAGTTGGTTTGGTAAGCTGAATAAATA
TCATGCGCCAAGTAATTCTTTGCTTATTACTCAGCTGATGATTCAAATCTTTATTATCATTACATATTTTGTAGCCAATG
CTTATAATGTCTTTATTTATATGGCAACAGCTGTAATTATGATTTGTTATGCTTTGGTTGGAGCTTATCTTCTTAAAATT
GGGATTAAAGAAGGTTCAATTAAAAATATATTAATAGGATTTTTCACCTTTGCTTTTCAAGCTCTGGCCCTTTATCTTTC
AGGTTGGCAATATGTTTGGTTGGCGATGATTCTTTATACGATTGGTTTCATTTTATTTATTAAAGCGAAAAAAGAAAGTC
GACAAGCAATATCAGTCAAAGAATGGGCAGGAATGTTCATTGTGGCCTTACTAGGAGTTTTAGCAATTCTGGTCTTGATT
TGTGGCGCAAAATCAGGAACAGCTTTAGATCTTCGGGGATTACTAGGCTACTAA

Upstream 100 bases:

>100_bases
AAAATAGTCTCTATATTCAAGAGACTCTTTTATATTTATAAATGATATTATACAAATTTAATTATAGGAAATTTATGATT
AAATAGTAGAAAGTGAGTAA

Downstream 100 bases:

>100_bases
ACAAAATATAAAAATAAGTTGTCTTATATAAATTAATTTTATCGGTATTTTTCTAAAAGTGAATAAAGGAGAGAATTGAT
GAGAACTTTTTCAGAAGTTA

Product: arginine/ornitine antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 497; Mature: 497

Protein sequence:

>497_residues
MENKKTKGISLFALLAIIISGAIGGGVFNLANDLANGSTPGGVMISWLFIGFGIFMLVLSFNRLITIRPKLSGVSDYARE
GFGDFIGFLSGWGYWISAWTGTIGFAVLMMTSADYFFPSKFANSNGSLTVLSVIIVSIISWILMFLVDRGVETAALVNAV
VMIAKLIPLVVFSITGIILFKADVFTQHFWQTFTSNLAADGSVKSLVWHAMTAGGLLDQIKGSLMVMVWVFVGIEGAAMM
GNRAKKKSDTAKATIIGLAVLLVIYVLLSLLPYGYMDQASLANVKAPGLVYILNEMVGGWGGSLMAIGLMISLLGAWLSW
TMLPVEATQQLAEKKLLPSWFGKLNKYHAPSNSLLITQLMIQIFIIITYFVANAYNVFIYMATAVIMICYALVGAYLLKI
GIKEGSIKNILIGFFTFAFQALALYLSGWQYVWLAMILYTIGFILFIKAKKESRQAISVKEWAGMFIVALLGVLAILVLI
CGAKSGTALDLRGLLGY

Sequences:

>Translated_497_residues
MENKKTKGISLFALLAIIISGAIGGGVFNLANDLANGSTPGGVMISWLFIGFGIFMLVLSFNRLITIRPKLSGVSDYARE
GFGDFIGFLSGWGYWISAWTGTIGFAVLMMTSADYFFPSKFANSNGSLTVLSVIIVSIISWILMFLVDRGVETAALVNAV
VMIAKLIPLVVFSITGIILFKADVFTQHFWQTFTSNLAADGSVKSLVWHAMTAGGLLDQIKGSLMVMVWVFVGIEGAAMM
GNRAKKKSDTAKATIIGLAVLLVIYVLLSLLPYGYMDQASLANVKAPGLVYILNEMVGGWGGSLMAIGLMISLLGAWLSW
TMLPVEATQQLAEKKLLPSWFGKLNKYHAPSNSLLITQLMIQIFIIITYFVANAYNVFIYMATAVIMICYALVGAYLLKI
GIKEGSIKNILIGFFTFAFQALALYLSGWQYVWLAMILYTIGFILFIKAKKESRQAISVKEWAGMFIVALLGVLAILVLI
CGAKSGTALDLRGLLGY
>Mature_497_residues
MENKKTKGISLFALLAIIISGAIGGGVFNLANDLANGSTPGGVMISWLFIGFGIFMLVLSFNRLITIRPKLSGVSDYARE
GFGDFIGFLSGWGYWISAWTGTIGFAVLMMTSADYFFPSKFANSNGSLTVLSVIIVSIISWILMFLVDRGVETAALVNAV
VMIAKLIPLVVFSITGIILFKADVFTQHFWQTFTSNLAADGSVKSLVWHAMTAGGLLDQIKGSLMVMVWVFVGIEGAAMM
GNRAKKKSDTAKATIIGLAVLLVIYVLLSLLPYGYMDQASLANVKAPGLVYILNEMVGGWGGSLMAIGLMISLLGAWLSW
TMLPVEATQQLAEKKLLPSWFGKLNKYHAPSNSLLITQLMIQIFIIITYFVANAYNVFIYMATAVIMICYALVGAYLLKI
GIKEGSIKNILIGFFTFAFQALALYLSGWQYVWLAMILYTIGFILFIKAKKESRQAISVKEWAGMFIVALLGVLAILVLI
CGAKSGTALDLRGLLGY

Specific function: Catalyzes an electroneutral exchange between arginine and ornithine to allow high-efficiency energy conversion in the arginine deiminase pathway [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI1787890, Length=454, Percent_Identity=34.1409691629956, Blast_Score=263, Evalue=2e-71,
Organism=Escherichia coli, GI2367353, Length=352, Percent_Identity=27.5568181818182, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1790575, Length=367, Percent_Identity=23.9782016348774, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004754
- InterPro:   IPR022461 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 53984; Mature: 53984

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCCCCCCEEEHHHHCCC
>Mature Secondary Structure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HCCCCCCEEEHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9696763 [H]