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The map label for this gene is dinP

Identifier: 15674011

GI number: 15674011

Start: 2104597

End: 2105688

Strand: Reverse

Name: dinP

Synonym: L0305

Alternate gene names: 15674011

Gene position: 2105688-2104597 (Counterclockwise)

Preceding gene: 15674012

Following gene: 15674009

Centisome position: 89.01

GC content: 34.98

Gene sequence:

>1092_bases
ATGTTAACTTTCCCACTCATCAATGACACTTCGCGAAAAATCATTCATATTGATATGGATGCCTTTTTTGCTTCTGTTGA
AGTGCGTGATAATCCGAGTTTAAAAGTTAAGCCGGTTGTTATTGCCAGAAATCCATTACAGACAGGTGGACGTGGCGTGG
TTTCAACTTGTTCTTATGAAGCGCGTGCTTTTGGAATACATTCGGCAAGTGCTAAAGAAGCTTATGATCTTTGCCCACAA
GCTATTTTTATTTCAGGAAACTATGAAAAATACACAAAAGTAAGTAAACAAGTTCGTGAAATCTTTAAACGTTATACCGA
TGATATTGAAGCAGCTTCAATTGATGAGGCCTATTTAGATGTAACAGAAAATAAAATCGGTGCTCAATCAGCAATTAAAA
TTGCTAAGTTGATTCAGCATGATATATTTGTTGAGTTAGGTTTAACCTGTTCTGCAGGAGTTTCTTATAATAAATTTTTA
GCGAAAATTGCATCTGATTATGAAAAGCCCCATGGCTTAACCTTAATTATGCCAGAAGAAGCATTAGAATTTTTAGCAAA
ATTACCGGTGGAAAAATTTCATGGTGTTGGAAAAGCAACAGTTCCTAAATTGCACGCACTAGGTTTCTTTAATGGGGGAG
ATTTACAAAAAGCAGACCCAGTTGATTTAGCTGAAAGATTCGGAGTTTATGGTTGGGAGCTTTATCAAAAGGCCAATGGA
ATACATAACTCGAAAGTCAAAAATTACCGTGAGCGAAAGTCAGTTGGAAAAGAACGAACTTATGGTAAACTATTATATCT
TCCGGATGATATTAAAGCAGAGTTGAGTAAAATTTCTGGCAAAGTTTCCGACTCATTAAAGAGTCATCAATTAAAAGGAA
GTATTGTCATTTTAAAATTGAGATATTCTGATTTTACAACATTGACAAAAAGAAAATCTTTAGCAGAAAAGTTAGAAAGT
CCAGAAGAAATTGCAGAAGTAGCACAAGAGATATTTGAAGAGCTTGAATATGATGAAAGTTTAGGAGTAAGGCTTTTAGG
GGTTACGGTGACAGAATTTGGTGCCCAAAAAGCAACATTAGATATGCAATAG

Upstream 100 bases:

>100_bases
ATATCAAATTATTGATTTATAAATTAAAACTCTTACTTGTTAAGAGTTTTTTTGTAATCAATCTATTGAGTCTGAAAACT
AATTCTTGTATAATAGCAAT

Downstream 100 bases:

>100_bases
TTAGAAACGGGATGAAGGCAATTTCAACTCGTTTTTTTGTGATTAGATAATAAATGATACCAAGTGAACAAGCGATTTGA
AGGAGCAGCATTTCGTTTAA

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MLTFPLINDTSRKIIHIDMDAFFASVEVRDNPSLKVKPVVIARNPLQTGGRGVVSTCSYEARAFGIHSASAKEAYDLCPQ
AIFISGNYEKYTKVSKQVREIFKRYTDDIEAASIDEAYLDVTENKIGAQSAIKIAKLIQHDIFVELGLTCSAGVSYNKFL
AKIASDYEKPHGLTLIMPEEALEFLAKLPVEKFHGVGKATVPKLHALGFFNGGDLQKADPVDLAERFGVYGWELYQKANG
IHNSKVKNYRERKSVGKERTYGKLLYLPDDIKAELSKISGKVSDSLKSHQLKGSIVILKLRYSDFTTLTKRKSLAEKLES
PEEIAEVAQEIFEELEYDESLGVRLLGVTVTEFGAQKATLDMQ

Sequences:

>Translated_363_residues
MLTFPLINDTSRKIIHIDMDAFFASVEVRDNPSLKVKPVVIARNPLQTGGRGVVSTCSYEARAFGIHSASAKEAYDLCPQ
AIFISGNYEKYTKVSKQVREIFKRYTDDIEAASIDEAYLDVTENKIGAQSAIKIAKLIQHDIFVELGLTCSAGVSYNKFL
AKIASDYEKPHGLTLIMPEEALEFLAKLPVEKFHGVGKATVPKLHALGFFNGGDLQKADPVDLAERFGVYGWELYQKANG
IHNSKVKNYRERKSVGKERTYGKLLYLPDDIKAELSKISGKVSDSLKSHQLKGSIVILKLRYSDFTTLTKRKSLAEKLES
PEEIAEVAQEIFEELEYDESLGVRLLGVTVTEFGAQKATLDMQ
>Mature_363_residues
MLTFPLINDTSRKIIHIDMDAFFASVEVRDNPSLKVKPVVIARNPLQTGGRGVVSTCSYEARAFGIHSASAKEAYDLCPQ
AIFISGNYEKYTKVSKQVREIFKRYTDDIEAASIDEAYLDVTENKIGAQSAIKIAKLIQHDIFVELGLTCSAGVSYNKFL
AKIASDYEKPHGLTLIMPEEALEFLAKLPVEKFHGVGKATVPKLHALGFFNGGDLQKADPVDLAERFGVYGWELYQKANG
IHNSKVKNYRERKSVGKERTYGKLLYLPDDIKAELSKISGKVSDSLKSHQLKGSIVILKLRYSDFTTLTKRKSLAEKLES
PEEIAEVAQEIFEELEYDESLGVRLLGVTVTEFGAQKATLDMQ

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=340, Percent_Identity=30, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI7706681, Length=341, Percent_Identity=29.9120234604106, Blast_Score=138, Evalue=6e-33,
Organism=Homo sapiens, GI154350220, Length=298, Percent_Identity=28.5234899328859, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI7705344, Length=115, Percent_Identity=46.0869565217391, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI5729982, Length=119, Percent_Identity=42.0168067226891, Blast_Score=82, Evalue=9e-16,
Organism=Escherichia coli, GI1786425, Length=354, Percent_Identity=41.8079096045198, Blast_Score=240, Evalue=9e-65,
Organism=Escherichia coli, GI1787432, Length=223, Percent_Identity=28.2511210762332, Blast_Score=78, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI193205700, Length=412, Percent_Identity=27.9126213592233, Blast_Score=124, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI17537959, Length=310, Percent_Identity=27.4193548387097, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI193205702, Length=346, Percent_Identity=26.878612716763, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI115534089, Length=369, Percent_Identity=25.7452574525745, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI19923006, Length=345, Percent_Identity=25.5072463768116, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI21355641, Length=286, Percent_Identity=27.6223776223776, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24644984, Length=286, Percent_Identity=27.6223776223776, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24668444, Length=127, Percent_Identity=34.6456692913386, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 40439; Mature: 40439

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTFPLINDTSRKIIHIDMDAFFASVEVRDNPSLKVKPVVIARNPLQTGGRGVVSTCSYE
CEEECCCCCCCCEEEEEEHHHEEEEEEECCCCCEEEEEEEEECCCCCCCCCCEEEECCCC
ARAFGIHSASAKEAYDLCPQAIFISGNYEKYTKVSKQVREIFKRYTDDIEAASIDEAYLD
HHEEECCCCCHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
VTENKIGAQSAIKIAKLIQHDIFVELGLTCSAGVSYNKFLAKIASDYEKPHGLTLIMPEE
HHCCCCCHHHHHHHHHHHHHHHHEEECCEECCCCCHHHHHHHHHHHCCCCCCEEEEEHHH
ALEFLAKLPVEKFHGVGKATVPKLHALGFFNGGDLQKADPVDLAERFGVYGWELYQKANG
HHHHHHHCCHHHHCCCCCCCCCHHHEEEECCCCCCCCCCCHHHHHHCCCCHHHHHHHHCC
IHNSKVKNYRERKSVGKERTYGKLLYLPDDIKAELSKISGKVSDSLKSHQLKGSIVILKL
CCHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
RYSDFTTLTKRKSLAEKLESPEEIAEVAQEIFEELEYDESLGVRLLGVTVTEFGAQKATL
ECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHCCCCCEEE
DMQ
CCC
>Mature Secondary Structure
MLTFPLINDTSRKIIHIDMDAFFASVEVRDNPSLKVKPVVIARNPLQTGGRGVVSTCSYE
CEEECCCCCCCCEEEEEEHHHEEEEEEECCCCCEEEEEEEEECCCCCCCCCCEEEECCCC
ARAFGIHSASAKEAYDLCPQAIFISGNYEKYTKVSKQVREIFKRYTDDIEAASIDEAYLD
HHEEECCCCCHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
VTENKIGAQSAIKIAKLIQHDIFVELGLTCSAGVSYNKFLAKIASDYEKPHGLTLIMPEE
HHCCCCCHHHHHHHHHHHHHHHHEEECCEECCCCCHHHHHHHHHHHCCCCCCEEEEEHHH
ALEFLAKLPVEKFHGVGKATVPKLHALGFFNGGDLQKADPVDLAERFGVYGWELYQKANG
HHHHHHHCCHHHHCCCCCCCCCHHHEEEECCCCCCCCCCCHHHHHHCCCCHHHHHHHHCC
IHNSKVKNYRERKSVGKERTYGKLLYLPDDIKAELSKISGKVSDSLKSHQLKGSIVILKL
CCHHHHHHHHHHHHCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
RYSDFTTLTKRKSLAEKLESPEEIAEVAQEIFEELEYDESLGVRLLGVTVTEFGAQKATL
ECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHCCCCCEEE
DMQ
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA