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The map label for this gene is frr

Identifier: 15673991

GI number: 15673991

Start: 2086423

End: 2086980

Strand: Reverse

Name: frr

Synonym: L0367

Alternate gene names: 15673991

Gene position: 2086980-2086423 (Counterclockwise)

Preceding gene: 15673992

Following gene: 15673990

Centisome position: 88.22

GC content: 38.53

Gene sequence:

>558_bases
ATGGCAAACGAAATTGTTACAACAGCTCAAGACCGGATGAAACAATCATTAGGAAGTTTACAACGTGATTTAGGACATAT
CCGAGCTGGTCGTGCCAACGCAAGTCTTCTTGACCGTGTTCAAGTTGTTTACTACGGCGCACCAACACCACTCAATCAAT
TAGCGTCAATCACAATTCCAGAAGCGCGCGTATTGATGGTTACTCCTTTTGATAAATCAATCTTGAAAGATATTGAAAAA
GCATTGTATGAATCAGATCTTGGGATTACACCAGCAAATGATGGTTCTGTGATTCGTTTAGTTATCCCAATGTTGACAGA
AGAACGCCGTCGCGAACTTGTCAAAGAAATGGGTAAATATATTGAATCAGCAAAAGTAGCAATCCGTAATATCCGTCGTG
ATGCAATGGACACTGCTAAGAAATCAGAAAAAGCAAAAGAAATCACTGAAGATGATCTTAAAGATCTTGAAAACAACATT
CAAAAAGTGACTGATGACGCGGTTAAAGAAGCAGACCGTCTTGCATCAATTAAAGAAAAAGAATTGTTGGATATCTAA

Upstream 100 bases:

>100_bases
ACTAGCATAACTGTAATCATTAAAACACTAACACTTATCTCTGACAAAGTTTCTGTCAGTAAAATAAATAGAAGAATTAA
AAAAAGAAAAAGGAAATAAA

Downstream 100 bases:

>100_bases
GTAGAACAATCTAACAAATAAAGTAATCTGTAAAAGCATTAACGGCTCCATTGAGCCGTTTTTACATCAAAAATCTGTCA
GGATGGATAAATTTGAGAGA

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MANEIVTTAQDRMKQSLGSLQRDLGHIRAGRANASLLDRVQVVYYGAPTPLNQLASITIPEARVLMVTPFDKSILKDIEK
ALYESDLGITPANDGSVIRLVIPMLTEERRRELVKEMGKYIESAKVAIRNIRRDAMDTAKKSEKAKEITEDDLKDLENNI
QKVTDDAVKEADRLASIKEKELLDI

Sequences:

>Translated_185_residues
MANEIVTTAQDRMKQSLGSLQRDLGHIRAGRANASLLDRVQVVYYGAPTPLNQLASITIPEARVLMVTPFDKSILKDIEK
ALYESDLGITPANDGSVIRLVIPMLTEERRRELVKEMGKYIESAKVAIRNIRRDAMDTAKKSEKAKEITEDDLKDLENNI
QKVTDDAVKEADRLASIKEKELLDI
>Mature_184_residues
ANEIVTTAQDRMKQSLGSLQRDLGHIRAGRANASLLDRVQVVYYGAPTPLNQLASITIPEARVLMVTPFDKSILKDIEKA
LYESDLGITPANDGSVIRLVIPMLTEERRRELVKEMGKYIESAKVAIRNIRRDAMDTAKKSEKAKEITEDDLKDLENNIQ
KVTDDAVKEADRLASIKEKELLDI

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=175, Percent_Identity=30.8571428571429, Blast_Score=81, Evalue=7e-16,
Organism=Homo sapiens, GI291042689, Length=160, Percent_Identity=33.125, Blast_Score=80, Evalue=1e-15,
Organism=Escherichia coli, GI1786368, Length=183, Percent_Identity=44.8087431693989, Blast_Score=152, Evalue=1e-38,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_LACLA (Q9CE39)

Other databases:

- EMBL:   AE005176
- PIR:   A86876
- RefSeq:   NP_268166.1
- ProteinModelPortal:   Q9CE39
- SMR:   Q9CE39
- GeneID:   1115685
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L0367
- NMPDR:   fig|272623.1.peg.2063
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- ProtClustDB:   PRK00083
- BioCyc:   LLAC272623:L0367-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20748; Mature: 20617

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANEIVTTAQDRMKQSLGSLQRDLGHIRAGRANASLLDRVQVVYYGAPTPLNQLASITIP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHEEECCCCCHHHHHHCCCC
EARVLMVTPFDKSILKDIEKALYESDLGITPANDGSVIRLVIPMLTEERRRELVKEMGKY
CCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IESAKVAIRNIRRDAMDTAKKSEKAKEITEDDLKDLENNIQKVTDDAVKEADRLASIKEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELLDI
HHCCC
>Mature Secondary Structure 
ANEIVTTAQDRMKQSLGSLQRDLGHIRAGRANASLLDRVQVVYYGAPTPLNQLASITIP
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHEEECCCCCHHHHHHCCCC
EARVLMVTPFDKSILKDIEKALYESDLGITPANDGSVIRLVIPMLTEERRRELVKEMGKY
CCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IESAKVAIRNIRRDAMDTAKKSEKAKEITEDDLKDLENNIQKVTDDAVKEADRLASIKEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELLDI
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471