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The map label for this gene is nah

Identifier: 15673897

GI number: 15673897

Start: 1992968

End: 1994107

Strand: Reverse

Name: nah

Synonym: L176399

Alternate gene names: 15673897

Gene position: 1994107-1992968 (Counterclockwise)

Preceding gene: 15673898

Following gene: 15673896

Centisome position: 84.3

GC content: 35.09

Gene sequence:

>1140_bases
ATGAATGATATTTTACAACTCACAATTGTTTTAATTGCCTCTTTAATTGCTACTCTTGTTTCAAGACGCCTTAAAATTCC
AGCTGTCGTTGGACAAATGCTTGTTGGGATTTTGATTGCTCCATCAGTTTTAGGCTTGGTTCATAGCGGTCATGTTCTAG
AAGTGATGTCTGAGATTGGAGTTATCTTACTCATGTTCTTAGCAGGAATTGAGAGTGATTTAACTGTTCTAAAGAAAAAT
TTTAAAGCATCAATGCTCGTTGCAGTTGGTGGTGTAATTGTGCCATTAATTGCCTTTGGACTTGTTGCTTTTGGCTTTGG
TTACGGAATATCGACCAGTTTCTTTTATGGAATTGTTTTCGCTGCGACCTCAGTGTCGATTACGGTTGAAGTCTTACAAG
AATATGGTAAACTCAGTACACGTGCAGGTTCGATTATTCTAGGAGCAGCAGTTGTTGATGATATTTTAGCTGTATTGATT
TTATCAATTTTTACTAGTTTTAAAAATGGTGGTTCTGGTTCTCATCTTTTCATCCAATTTTTGCTTGAACTTCTCTTTTT
TGCCTTTTTATTTCTTGTGCATAAGCTTATTCCAAGATTTTGGAAATTCGTCCAAAAACTACCCATTGCCAACAAAAATA
CGATTGTTGCCTTGATTATTTGTTTGGGCTTAAGTCTACTTGCTGATAGCGTAGGAATGTCAGCGGTAATAGGTAGTTTC
TTTGCAGGACTTGCTATTTCACAAACAGAAGTAAGTCATAAGATTGAAGAATATACTTCAGCAATCGGTTATGTTATTTT
TATCCCAGTATTCTTTGTACTTATCGCCATATCTGTTCAATTCGATAGTTTAATTCATCATCCTTGGATAATTTTACTCT
TTACCTTCTTAGCAATTTTGACAAAATTTATCCCCGCCTATTTTGTTGGAAAAGCAAGTAAATTAAGTACTGGTGAGAGT
ATGTTGATTGGAACAGGAATGATTTCACGAGGAGAAATGGCCCTGATTGTGGCTCAAATTGGTCTGACGAGTGCCATTAT
TACAGATGAAGTTTATTCGGAGCTGGTTATCGTGATTATTTTAGCAACTGTATTAGCACCATTTTTAATTAAAATGGTCT
TGAAAAAATATGATAATTAA

Upstream 100 bases:

>100_bases
GACTGAAGAAGCAAGCAAACGACTCGTAGAAACATTCAAAATTTAAGGATTTTAGTCGAAAATGTGTTTTTAAGAATGAA
AAATATGTTAAAATCAACTT

Downstream 100 bases:

>100_bases
GAAAAAATAAAGAATAAAAGACGAAAAATTTAAATTTTTTTAAATTTCATCTTATTCCTCCCAAAAAGACCAAAAAAGTG
GTAAAATAGAAAAAATGCTT

Product: Na+/H+ antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MNDILQLTIVLIASLIATLVSRRLKIPAVVGQMLVGILIAPSVLGLVHSGHVLEVMSEIGVILLMFLAGIESDLTVLKKN
FKASMLVAVGGVIVPLIAFGLVAFGFGYGISTSFFYGIVFAATSVSITVEVLQEYGKLSTRAGSIILGAAVVDDILAVLI
LSIFTSFKNGGSGSHLFIQFLLELLFFAFLFLVHKLIPRFWKFVQKLPIANKNTIVALIICLGLSLLADSVGMSAVIGSF
FAGLAISQTEVSHKIEEYTSAIGYVIFIPVFFVLIAISVQFDSLIHHPWIILLFTFLAILTKFIPAYFVGKASKLSTGES
MLIGTGMISRGEMALIVAQIGLTSAIITDEVYSELVIVIILATVLAPFLIKMVLKKYDN

Sequences:

>Translated_379_residues
MNDILQLTIVLIASLIATLVSRRLKIPAVVGQMLVGILIAPSVLGLVHSGHVLEVMSEIGVILLMFLAGIESDLTVLKKN
FKASMLVAVGGVIVPLIAFGLVAFGFGYGISTSFFYGIVFAATSVSITVEVLQEYGKLSTRAGSIILGAAVVDDILAVLI
LSIFTSFKNGGSGSHLFIQFLLELLFFAFLFLVHKLIPRFWKFVQKLPIANKNTIVALIICLGLSLLADSVGMSAVIGSF
FAGLAISQTEVSHKIEEYTSAIGYVIFIPVFFVLIAISVQFDSLIHHPWIILLFTFLAILTKFIPAYFVGKASKLSTGES
MLIGTGMISRGEMALIVAQIGLTSAIITDEVYSELVIVIILATVLAPFLIKMVLKKYDN
>Mature_379_residues
MNDILQLTIVLIASLIATLVSRRLKIPAVVGQMLVGILIAPSVLGLVHSGHVLEVMSEIGVILLMFLAGIESDLTVLKKN
FKASMLVAVGGVIVPLIAFGLVAFGFGYGISTSFFYGIVFAATSVSITVEVLQEYGKLSTRAGSIILGAAVVDDILAVLI
LSIFTSFKNGGSGSHLFIQFLLELLFFAFLFLVHKLIPRFWKFVQKLPIANKNTIVALIICLGLSLLADSVGMSAVIGSF
FAGLAISQTEVSHKIEEYTSAIGYVIFIPVFFVLIAISVQFDSLIHHPWIILLFTFLAILTKFIPAYFVGKASKLSTGES
MLIGTGMISRGEMALIVAQIGLTSAIITDEVYSELVIVIILATVLAPFLIKMVLKKYDN

Specific function: This is a Na(+)/H(+) antiporter. It can mediate sodium uptake when a transmembrane pH gradient is applied [H]

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family [H]

Homologues:

Organism=Escherichia coli, GI1786685, Length=389, Percent_Identity=24.6786632390745, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789749, Length=366, Percent_Identity=20.4918032786885, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1786232, Length=365, Percent_Identity=24.1095890410959, Blast_Score=75, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6322367, Length=409, Percent_Identity=24.4498777506112, Blast_Score=96, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR004771 [H]

Pfam domain/function: PF00999 Na_H_Exchanger [H]

EC number: NA

Molecular weight: Translated: 40809; Mature: 40809

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: PS00307 LECTIN_LEGUME_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDILQLTIVLIASLIATLVSRRLKIPAVVGQMLVGILIAPSVLGLVHSGHVLEVMSEIG
CCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
VILLMFLAGIESDLTVLKKNFKASMLVAVGGVIVPLIAFGLVAFGFGYGISTSFFYGIVF
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AATSVSITVEVLQEYGKLSTRAGSIILGAAVVDDILAVLILSIFTSFKNGGSGSHLFIQF
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LLELLFFAFLFLVHKLIPRFWKFVQKLPIANKNTIVALIICLGLSLLADSVGMSAVIGSF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAGLAISQTEVSHKIEEYTSAIGYVIFIPVFFVLIAISVQFDSLIHHPWIILLFTFLAIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TKFIPAYFVGKASKLSTGESMLIGTGMISRGEMALIVAQIGLTSAIITDEVYSELVIVII
HHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LATVLAPFLIKMVLKKYDN
HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNDILQLTIVLIASLIATLVSRRLKIPAVVGQMLVGILIAPSVLGLVHSGHVLEVMSEIG
CCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
VILLMFLAGIESDLTVLKKNFKASMLVAVGGVIVPLIAFGLVAFGFGYGISTSFFYGIVF
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AATSVSITVEVLQEYGKLSTRAGSIILGAAVVDDILAVLILSIFTSFKNGGSGSHLFIQF
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LLELLFFAFLFLVHKLIPRFWKFVQKLPIANKNTIVALIICLGLSLLADSVGMSAVIGSF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAGLAISQTEVSHKIEEYTSAIGYVIFIPVFFVLIAISVQFDSLIHHPWIILLFTFLAIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TKFIPAYFVGKASKLSTGESMLIGTGMISRGEMALIVAQIGLTSAIITDEVYSELVIVII
HHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LATVLAPFLIKMVLKKYDN
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1312090; 1325937 [H]