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The map label for this gene is pepQ

Identifier: 15673631

GI number: 15673631

Start: 1697143

End: 1698231

Strand: Direct

Name: pepQ

Synonym: L96847

Alternate gene names: 15673631

Gene position: 1697143-1698231 (Clockwise)

Preceding gene: 15673615

Following gene: 15673639

Centisome position: 71.74

GC content: 37.74

Gene sequence:

>1089_bases
TTGAGCAAAATTGAACGTATTTCAGCTTTTCTGAATGACAAGGAAGTCGATATGACTTTCATCACTAATCCGACAACTCT
AAATTATCTAACAGGGCTAGCAATTGATCCCCATGAACGAATTGCTGGGCTGATGATTTTTAGAGATTCAACTCCGATGT
TATTTACTCCTGCTTTGGAAGTGGAAAAAGCTAAAGAATACACAAGTGGTCTGGATATTTTCGGATATGAAGATTCTCAA
AACCCTTGGGAAGTTGTTAAAAATCATGTAAAATCAGATGTTAAATCAATTGCTGTTGAATTTTCAGATATTCCTTTAGC
TAAAACTGAAGGGTTGAAAGCACAATTTGGTGATATTAATTTTGTAAATTTGACTCCTTTGATTGAACGGATGCGTTTGA
TTAAGTCAGCAGATGAAATTGAAAAAATGAAAGTTGCTGGTGATTTTGCTGACAAGTGTTTTGAAATTGGTTTTGCCACT
GCTGCTGAACGTAATGGTGTGACTGAATCTGATATCGTTGCAAAAATTGAATACGAAATGAAACGTATGGGTGTTCCACA
GATGTCATTTGACACGCTTGTTTTATCAGGAGCTCGCGCTGCTAATCCACATGGTGCACCTGAAAATGTTGAAATTCAAG
AAAATAAACTTTTGCTCTTTGACTTGGGTGTGATGAGTGGCGGATATGCTTCTGATGCGACACGTACAATCGCTATTGGT
CAACCTAATGACTTTGATGCTGAGATCCATAAAATCGTTAAGGAAGCTCAACAAGCAGCCATGGACTTCATTAAACCTGG
TGTAACTGCACATGAAGTTGATGCTGTTGCTCGTGATTTAATTACTAAAGCAGGATATGGTGAATATTTCAATCACCGCC
TTGGACATGGTATCGGAATGGACGTTCACGAATATCCATCTATTGTTGCCGGAAATGACCTCGTAATTCAAGAAGGAATG
TGCTTCTCTAACGAACCTGGAATTTATATTCCTGGTAAAGTAGGTGTGCGTATTGAAGACTGTCTTTACGTAACAGAAAA
TGGTTGTGAAAGCTTCACTCATACTGACCATGACTTATTAATTTTCTAA

Upstream 100 bases:

>100_bases
GTGATTTTTTAATAAAAATAGCGTAGAATAGGGAATATAGTGTTTTTTATTTTCATGAGAATTTAAGAAACTCATTTTCA
TAAATATTGGAGGAACCATT

Downstream 100 bases:

>100_bases
TCGAATAATTGATAAAAGTAAAAAACTTTCGCTGATTTTGGCGAAAGTTTTTTTGTCAGTAAATTTTTGTCAGTAAGTTT
CTGTCAGTAAAAAAAATAAT

Product: proline dipeptidase

Products: NA

Alternate protein names: X-Pro dipeptidase; Imidodipeptidase; Proline dipeptidase; Prolidase [H]

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MSKIERISAFLNDKEVDMTFITNPTTLNYLTGLAIDPHERIAGLMIFRDSTPMLFTPALEVEKAKEYTSGLDIFGYEDSQ
NPWEVVKNHVKSDVKSIAVEFSDIPLAKTEGLKAQFGDINFVNLTPLIERMRLIKSADEIEKMKVAGDFADKCFEIGFAT
AAERNGVTESDIVAKIEYEMKRMGVPQMSFDTLVLSGARAANPHGAPENVEIQENKLLLFDLGVMSGGYASDATRTIAIG
QPNDFDAEIHKIVKEAQQAAMDFIKPGVTAHEVDAVARDLITKAGYGEYFNHRLGHGIGMDVHEYPSIVAGNDLVIQEGM
CFSNEPGIYIPGKVGVRIEDCLYVTENGCESFTHTDHDLLIF

Sequences:

>Translated_362_residues
MSKIERISAFLNDKEVDMTFITNPTTLNYLTGLAIDPHERIAGLMIFRDSTPMLFTPALEVEKAKEYTSGLDIFGYEDSQ
NPWEVVKNHVKSDVKSIAVEFSDIPLAKTEGLKAQFGDINFVNLTPLIERMRLIKSADEIEKMKVAGDFADKCFEIGFAT
AAERNGVTESDIVAKIEYEMKRMGVPQMSFDTLVLSGARAANPHGAPENVEIQENKLLLFDLGVMSGGYASDATRTIAIG
QPNDFDAEIHKIVKEAQQAAMDFIKPGVTAHEVDAVARDLITKAGYGEYFNHRLGHGIGMDVHEYPSIVAGNDLVIQEGM
CFSNEPGIYIPGKVGVRIEDCLYVTENGCESFTHTDHDLLIF
>Mature_361_residues
SKIERISAFLNDKEVDMTFITNPTTLNYLTGLAIDPHERIAGLMIFRDSTPMLFTPALEVEKAKEYTSGLDIFGYEDSQN
PWEVVKNHVKSDVKSIAVEFSDIPLAKTEGLKAQFGDINFVNLTPLIERMRLIKSADEIEKMKVAGDFADKCFEIGFATA
AERNGVTESDIVAKIEYEMKRMGVPQMSFDTLVLSGARAANPHGAPENVEIQENKLLLFDLGVMSGGYASDATRTIAIGQ
PNDFDAEIHKIVKEAQQAAMDFIKPGVTAHEVDAVARDLITKAGYGEYFNHRLGHGIGMDVHEYPSIVAGNDLVIQEGMC
FSNEPGIYIPGKVGVRIEDCLYVTENGCESFTHTDHDLLIF

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=251, Percent_Identity=31.8725099601594, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI93141226, Length=164, Percent_Identity=34.1463414634146, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI264681563, Length=191, Percent_Identity=29.8429319371728, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1788728, Length=289, Percent_Identity=34.9480968858132, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI1789275, Length=262, Percent_Identity=28.6259541984733, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1786364, Length=263, Percent_Identity=24.3346007604563, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17509539, Length=250, Percent_Identity=27.2, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71989583, Length=261, Percent_Identity=24.904214559387, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6321118, Length=295, Percent_Identity=26.1016949152542, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6320922, Length=254, Percent_Identity=23.2283464566929, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322999, Length=173, Percent_Identity=32.9479768786127, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI19920384, Length=255, Percent_Identity=28.2352941176471, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI17137632, Length=375, Percent_Identity=25.3333333333333, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21355531, Length=242, Percent_Identity=25.6198347107438, Blast_Score=68, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: =3.4.13.9 [H]

Molecular weight: Translated: 39996; Mature: 39865

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS00491 PROLINE_PEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIERISAFLNDKEVDMTFITNPTTLNYLTGLAIDPHERIAGLMIFRDSTPMLFTPALE
CCHHHHHHHHHCCCCEEEEEEECCCEEHHHCCCEECHHHHHEEEEEEECCCCEEEECCHH
VEKAKEYTSGLDIFGYEDSQNPWEVVKNHVKSDVKSIAVEFSDIPLAKTEGLKAQFGDIN
HHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCEE
FVNLTPLIERMRLIKSADEIEKMKVAGDFADKCFEIGFATAAERNGVTESDIVAKIEYEM
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
KRMGVPQMSFDTLVLSGARAANPHGAPENVEIQENKLLLFDLGVMSGGYASDATRTIAIG
HHCCCCCCCCCHHEEECCCCCCCCCCCCCCEEECCEEEEEEECCCCCCCCCCCCEEEEEC
QPNDFDAEIHKIVKEAQQAAMDFIKPGVTAHEVDAVARDLITKAGYGEYFNHRLGHGIGM
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCC
DVHEYPSIVAGNDLVIQEGMCFSNEPGIYIPGKVGVRIEDCLYVTENGCESFTHTDHDLL
CHHHCCCEECCCCEEEECCCCCCCCCCEEECCCCCEEEEEEEEEECCCCCCCCCCCCCEE
IF
EC
>Mature Secondary Structure 
SKIERISAFLNDKEVDMTFITNPTTLNYLTGLAIDPHERIAGLMIFRDSTPMLFTPALE
CHHHHHHHHHCCCCEEEEEEECCCEEHHHCCCEECHHHHHEEEEEEECCCCEEEECCHH
VEKAKEYTSGLDIFGYEDSQNPWEVVKNHVKSDVKSIAVEFSDIPLAKTEGLKAQFGDIN
HHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCEE
FVNLTPLIERMRLIKSADEIEKMKVAGDFADKCFEIGFATAAERNGVTESDIVAKIEYEM
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
KRMGVPQMSFDTLVLSGARAANPHGAPENVEIQENKLLLFDLGVMSGGYASDATRTIAIG
HHCCCCCCCCCHHEEECCCCCCCCCCCCCCEEECCEEEEEEECCCCCCCCCCCCEEEEEC
QPNDFDAEIHKIVKEAQQAAMDFIKPGVTAHEVDAVARDLITKAGYGEYFNHRLGHGIGM
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCC
DVHEYPSIVAGNDLVIQEGMCFSNEPGIYIPGKVGVRIEDCLYVTENGCESFTHTDHDLL
CHHHCCCEECCCCEEEECCCCCCCCCCEEECCCCCEEEEEEEEEECCCCCCCCCCCCCEE
IF
EC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA