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The map label for this gene is ilvH

Identifier: 15673207

GI number: 15673207

Start: 1249214

End: 1249690

Strand: Direct

Name: ilvH

Synonym: L0079

Alternate gene names: 15673207

Gene position: 1249214-1249690 (Clockwise)

Preceding gene: 15673206

Following gene: 15673208

Centisome position: 52.81

GC content: 36.48

Gene sequence:

>477_bases
ATGCGTAGAATGATTATCGCAAAACTTCATAATGTAACAGGAATTATGAATCGATTTACCGCCGTTCTCAATCGAAGGCA
AGTGAACATTCTCTCAATTACCGCTGGAGTTACAGAAAGTCAAGACTTAACTCATACCACTTTTGTTATTGAAGTTGATC
ATCTTGATGAAGTAGAACAAATCATTAAACAATTAAATCGCTTAATAGATGTGATTGAAGTAGCTGATATTACAGATTTG
CCTCATGTAGAACGTGAAGTCGTCTTGATTAAAGTATCAGCTCCACCGACCATTAGGGCAGAAATTTTTACAATGATTGA
ACCTTTTAGAGTAAATGTAGTTGATGTCAATCTGGAAAATGTCACCATTCAATTAACGGGTGATTCAGCAAAAATCGAAG
CACTTATTGATGTTGTTAGTCCTTATGGCATTCTAAATATGGCTCGGACAGGTAGTGCAGGTTTTGAGCGTGGCTAA

Upstream 100 bases:

>100_bases
ATTTCAAAATCTGAACATGTTTTACCAATGATACCAGCTGGGTTACACAGTGACGAAATGATTGGACTTCATTTTACTGA
TGAGAATGAGGAGGTAGATA

Downstream 100 bases:

>100_bases
ATTTAAATAAGTTAACAAATAAATAGAAAAATAGAGGAAACAAAAATGGCAGTTACAATGTATTATGAAGATGATGTAGA
AGTATCAGCACTTGCTGGAA

Product: acetolactate synthase 3 regulatory subunit

Products: NA

Alternate protein names: Acetohydroxy-acid synthase small subunit; AHAS; ALS

Number of amino acids: Translated: 158; Mature: 158

Protein sequence:

>158_residues
MRRMIIAKLHNVTGIMNRFTAVLNRRQVNILSITAGVTESQDLTHTTFVIEVDHLDEVEQIIKQLNRLIDVIEVADITDL
PHVEREVVLIKVSAPPTIRAEIFTMIEPFRVNVVDVNLENVTIQLTGDSAKIEALIDVVSPYGILNMARTGSAGFERG

Sequences:

>Translated_158_residues
MRRMIIAKLHNVTGIMNRFTAVLNRRQVNILSITAGVTESQDLTHTTFVIEVDHLDEVEQIIKQLNRLIDVIEVADITDL
PHVEREVVLIKVSAPPTIRAEIFTMIEPFRVNVVDVNLENVTIQLTGDSAKIEALIDVVSPYGILNMARTGSAGFERG
>Mature_158_residues
MRRMIIAKLHNVTGIMNRFTAVLNRRQVNILSITAGVTESQDLTHTTFVIEVDHLDEVEQIIKQLNRLIDVIEVADITDL
PHVEREVVLIKVSAPPTIRAEIFTMIEPFRVNVVDVNLENVTIQLTGDSAKIEALIDVVSPYGILNMARTGSAGFERG

Specific function: Valine and isoleucine biosynthesis; first step. [C]

COG id: COG0440

COG function: function code E; Acetolactate synthase, small (regulatory) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain

Homologues:

Organism=Escherichia coli, GI1786266, Length=159, Percent_Identity=34.5911949685535, Blast_Score=91, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ILVH_LACLA (Q02140)

Other databases:

- EMBL:   U92974
- EMBL:   AE005176
- PIR:   A86778
- PIR:   S35139
- RefSeq:   NP_267381.1
- ProteinModelPortal:   Q02140
- SMR:   Q02140
- GeneID:   1114874
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L0079
- NMPDR:   fig|272623.1.peg.1260
- HOGENOM:   HBG335310
- OMA:   TIRAEIF
- ProtClustDB:   PRK11895
- BioCyc:   LLAC272623:L0079-MONOMER
- BRENDA:   2.2.1.6
- InterPro:   IPR004789
- InterPro:   IPR019455
- InterPro:   IPR002912
- TIGRFAMs:   TIGR00119

Pfam domain/function: PF01842 ACT; PF10369 ALS_ss_C

EC number: =2.2.1.6

Molecular weight: Translated: 17642; Mature: 17642

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRMIIAKLHNVTGIMNRFTAVLNRRQVNILSITAGVTESQDLTHTTFVIEVDHLDEVEQ
CCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCEEEEEEEEECCHHHHHH
IIKQLNRLIDVIEVADITDLPHVEREVVLIKVSAPPTIRAEIFTMIEPFRVNVVDVNLEN
HHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCHHHHHEEEECCEEEEEEEEEECE
VTIQLTGDSAKIEALIDVVSPYGILNMARTGSAGFERG
EEEEEECCCHHHHHHHHHHCCCCCEEECCCCCCCCCCC
>Mature Secondary Structure
MRRMIIAKLHNVTGIMNRFTAVLNRRQVNILSITAGVTESQDLTHTTFVIEVDHLDEVEQ
CCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCEEEEEEEEECCHHHHHH
IIKQLNRLIDVIEVADITDLPHVEREVVLIKVSAPPTIRAEIFTMIEPFRVNVVDVNLEN
HHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCHHHHHEEEECCEEEEEEEEEECE
VTIQLTGDSAKIEALIDVVSPYGILNMARTGSAGFERG
EEEEEECCCHHHHHHHHHHCCCCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1400210; 11337471