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The map label for this gene is citF

Identifier: 15673173

GI number: 15673173

Start: 1208991

End: 1210529

Strand: Direct

Name: citF

Synonym: L0041

Alternate gene names: 15673173

Gene position: 1208991-1210529 (Clockwise)

Preceding gene: 15673172

Following gene: 15673174

Centisome position: 51.11

GC content: 44.25

Gene sequence:

>1539_bases
TTGAAAAATAAAGTGAACCGTGAATTGCCAGATGAAATTTTGAAAACTACAGGTTACAAACCTTTTGAGTCAGTCGAAGT
CAAGGACCTTGTGATTGAGCGCGTGAGTGCTAAAGTCCGTCAGTCTGTTAAACCAAATAAATTGGTAGATTCGCTGGAAG
AAGTGGTTTTGAAAACTGTTAAAGATGGTATGACCATTTCATTCCACCACCATTTCCGCGAAGGCGACTATGTTTTTAAT
AAAGTCATGCGCATTATCATTGACCACGGCTTTAAAGATTTGAGGATTGCTCCGTCTTCTTTGACCAATGTCATGAATGA
TATTTTGGTTGAGGCTATTGAAAAAGGTGTCGTGACAAACATTACTTCATCTGGGATGCGTGGAACTTTGGGCGATGTCG
TTTCTCACGGCGCTTTGAAAAATCCTGTTATTTTCCGTTCACATGGTGGTCGTGCGCGTGCTATTGAAACTGGTGAAATT
CATATTGACGTGGCTTTCTTGGGTACTCCAAATGCTGACGAAATGGGTAATGCCAACGGCATGGACGGTAAAGCACCATT
TGGATCATTGGGTTATGCTTTGATGGATGCTCAATATGCTGACACTGTTGTTGCCATTACTGACAGCCTTGTCAGCTATC
CTAATACTCCTGCCTCAATCAAACAAACGCAAGTCGATTACGTGGTTAAGATTGATGCGGTCGGTAATCCTGATAAAATC
GGGGCTGGTGCGACTCGTTTCACCAAAGACCCTAAAGAATTGAAAATTGCCTCTATGGTTAATGATGTTATTGTGAATTC
GCCTTATTTCAAAAACGGCTTTTCATTCCAAACTGGTACAGGTGGGGCTGCGCTTGCGGTTACTCGTTTCTTGCGCCAAT
CTATGATTGACCACAATGTCAAGGCCACATTTGGTTTGGGGGGTATTACTAAGCCAATGGTTGATTTGCTGGAAGAAGGC
TTGGTTGACAAGCTCATGGACGTGCAAGACTTCGACGGTGGCTCTGCTCAATCCATGCACCTCAACAAAAATCAACAAGA
AATCGACGCCTCTTGGTACGCTGACCCTGCCAACAAAGGCGCCATGGTCGATAAGCTTGACGTGGTTATCTTGTCTGCCT
TGGAAATTGACACCAAGTTCAACGTTAACGTTATGTCTGGTTCTGACGGTGTCATTCGTGGCGCTATCGGTGGTCACCAA
GACGCTGGGACAGCTAAATTGACGATTATTTCTGCACCTTTGGTGCGCGGTCGGATTGCGACAGTTGTGCCTGATGTGAC
GACGGTTATCACGCCTGGTGATTCGATTGACGTTTTGGTCACTGAAATCGGGATAGCTATCAATCCTAAGCGGACAGATT
TGCTTGATAAATTGAGCAATATTCCTGGTCTGCCAGTTTACACCATTGAAGAATTGCAAAAAATTGCTGAGGAAAAATTG
GGCAAGCCAGAACCGCTGGAATTTACCGACAAGGTGGTTGCCTTAATCGAATACCGTGACGGCAGCTTGCTTGATATCAT
TCGTGAAGTTAAAGATTGA

Upstream 100 bases:

>100_bases
TTGAATGGTCAAATGGTCGACCGTCCAATCGTGTTGCAAGCTGAACGTGTGTTGATGTTGGCTAAAGCCGCAAATGTGTT
AGATGAGGGAGGAAATTACA

Downstream 100 bases:

>100_bases
TTTTGATAGAATGGATATTGAATCATCAATATCTTTTCTTTTGTGAAAGGGTAGTCATGGATATTTTTGAAGGGGGTCAG
GCCGTTAGCCTGGCGGAAAT

Product: citrate lyase alpha chain

Products: NA

Alternate protein names: Citrase alpha chain; Citrate (pro-3S)-lyase alpha chain; Citrate CoA-transferase subunit [H]

Number of amino acids: Translated: 512; Mature: 512

Protein sequence:

>512_residues
MKNKVNRELPDEILKTTGYKPFESVEVKDLVIERVSAKVRQSVKPNKLVDSLEEVVLKTVKDGMTISFHHHFREGDYVFN
KVMRIIIDHGFKDLRIAPSSLTNVMNDILVEAIEKGVVTNITSSGMRGTLGDVVSHGALKNPVIFRSHGGRARAIETGEI
HIDVAFLGTPNADEMGNANGMDGKAPFGSLGYALMDAQYADTVVAITDSLVSYPNTPASIKQTQVDYVVKIDAVGNPDKI
GAGATRFTKDPKELKIASMVNDVIVNSPYFKNGFSFQTGTGGAALAVTRFLRQSMIDHNVKATFGLGGITKPMVDLLEEG
LVDKLMDVQDFDGGSAQSMHLNKNQQEIDASWYADPANKGAMVDKLDVVILSALEIDTKFNVNVMSGSDGVIRGAIGGHQ
DAGTAKLTIISAPLVRGRIATVVPDVTTVITPGDSIDVLVTEIGIAINPKRTDLLDKLSNIPGLPVYTIEELQKIAEEKL
GKPEPLEFTDKVVALIEYRDGSLLDIIREVKD

Sequences:

>Translated_512_residues
MKNKVNRELPDEILKTTGYKPFESVEVKDLVIERVSAKVRQSVKPNKLVDSLEEVVLKTVKDGMTISFHHHFREGDYVFN
KVMRIIIDHGFKDLRIAPSSLTNVMNDILVEAIEKGVVTNITSSGMRGTLGDVVSHGALKNPVIFRSHGGRARAIETGEI
HIDVAFLGTPNADEMGNANGMDGKAPFGSLGYALMDAQYADTVVAITDSLVSYPNTPASIKQTQVDYVVKIDAVGNPDKI
GAGATRFTKDPKELKIASMVNDVIVNSPYFKNGFSFQTGTGGAALAVTRFLRQSMIDHNVKATFGLGGITKPMVDLLEEG
LVDKLMDVQDFDGGSAQSMHLNKNQQEIDASWYADPANKGAMVDKLDVVILSALEIDTKFNVNVMSGSDGVIRGAIGGHQ
DAGTAKLTIISAPLVRGRIATVVPDVTTVITPGDSIDVLVTEIGIAINPKRTDLLDKLSNIPGLPVYTIEELQKIAEEKL
GKPEPLEFTDKVVALIEYRDGSLLDIIREVKD
>Mature_512_residues
MKNKVNRELPDEILKTTGYKPFESVEVKDLVIERVSAKVRQSVKPNKLVDSLEEVVLKTVKDGMTISFHHHFREGDYVFN
KVMRIIIDHGFKDLRIAPSSLTNVMNDILVEAIEKGVVTNITSSGMRGTLGDVVSHGALKNPVIFRSHGGRARAIETGEI
HIDVAFLGTPNADEMGNANGMDGKAPFGSLGYALMDAQYADTVVAITDSLVSYPNTPASIKQTQVDYVVKIDAVGNPDKI
GAGATRFTKDPKELKIASMVNDVIVNSPYFKNGFSFQTGTGGAALAVTRFLRQSMIDHNVKATFGLGGITKPMVDLLEEG
LVDKLMDVQDFDGGSAQSMHLNKNQQEIDASWYADPANKGAMVDKLDVVILSALEIDTKFNVNVMSGSDGVIRGAIGGHQ
DAGTAKLTIISAPLVRGRIATVVPDVTTVITPGDSIDVLVTEIGIAINPKRTDLLDKLSNIPGLPVYTIEELQKIAEEKL
GKPEPLEFTDKVVALIEYRDGSLLDIIREVKD

Specific function: Represents a citrate:acetyl-ACP transferase [H]

COG id: COG3051

COG function: function code C; Citrate lyase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786832, Length=474, Percent_Identity=55.6962025316456, Blast_Score=521, Evalue=1e-149,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006472 [H]

Pfam domain/function: PF04223 CitF [H]

EC number: =4.1.3.6; =2.8.3.10 [H]

Molecular weight: Translated: 55441; Mature: 55441

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKVNRELPDEILKTTGYKPFESVEVKDLVIERVSAKVRQSVKPNKLVDSLEEVVLKTV
CCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
KDGMTISFHHHFREGDYVFNKVMRIIIDHGFKDLRIAPSSLTNVMNDILVEAIEKGVVTN
HCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHCCCEEC
ITSSGMRGTLGDVVSHGALKNPVIFRSHGGRARAIETGEIHIDVAFLGTPNADEMGNANG
CCCCCCCCCHHHHHHCCCCCCCEEEECCCCCEEEEECCEEEEEEEEECCCCHHHCCCCCC
MDGKAPFGSLGYALMDAQYADTVVAITDSLVSYPNTPASIKQTQVDYVVKIDAVGNPDKI
CCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHCCEEEEEEEECCCCCCCC
GAGATRFTKDPKELKIASMVNDVIVNSPYFKNGFSFQTGTGGAALAVTRFLRQSMIDHNV
CCCCHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHCCCC
KATFGLGGITKPMVDLLEEGLVDKLMDVQDFDGGSAQSMHLNKNQQEIDASWYADPANKG
EEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCHHHHCHHHCCCCCCCC
AMVDKLDVVILSALEIDTKFNVNVMSGSDGVIRGAIGGHQDAGTAKLTIISAPLVRGRIA
CHHHHHHHHHHHHHEECCEEEEEEECCCCCEEEECCCCCCCCCCEEEEEEECCHHHCCHH
TVVPDVTTVITPGDSIDVLVTEIGIAINPKRTDLLDKLSNIPGLPVYTIEELQKIAEEKL
HHCCCCEEEECCCCCCEEEEEECCEEECCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHC
GKPEPLEFTDKVVALIEYRDGSLLDIIREVKD
CCCCCCCHHHHEEEEEEECCCHHHHHHHHHCC
>Mature Secondary Structure
MKNKVNRELPDEILKTTGYKPFESVEVKDLVIERVSAKVRQSVKPNKLVDSLEEVVLKTV
CCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
KDGMTISFHHHFREGDYVFNKVMRIIIDHGFKDLRIAPSSLTNVMNDILVEAIEKGVVTN
HCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHCCCEEC
ITSSGMRGTLGDVVSHGALKNPVIFRSHGGRARAIETGEIHIDVAFLGTPNADEMGNANG
CCCCCCCCCHHHHHHCCCCCCCEEEECCCCCEEEEECCEEEEEEEEECCCCHHHCCCCCC
MDGKAPFGSLGYALMDAQYADTVVAITDSLVSYPNTPASIKQTQVDYVVKIDAVGNPDKI
CCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHCCEEEEEEEECCCCCCCC
GAGATRFTKDPKELKIASMVNDVIVNSPYFKNGFSFQTGTGGAALAVTRFLRQSMIDHNV
CCCCHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHCCCC
KATFGLGGITKPMVDLLEEGLVDKLMDVQDFDGGSAQSMHLNKNQQEIDASWYADPANKG
EEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCHHHHCHHHCCCCCCCC
AMVDKLDVVILSALEIDTKFNVNVMSGSDGVIRGAIGGHQDAGTAKLTIISAPLVRGRIA
CHHHHHHHHHHHHHEECCEEEEEEECCCCCEEEECCCCCCCCCCEEEEEEECCHHHCCHH
TVVPDVTTVITPGDSIDVLVTEIGIAINPKRTDLLDKLSNIPGLPVYTIEELQKIAEEKL
HHCCCCEEEECCCCCCEEEEEECCEEECCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHC
GKPEPLEFTDKVVALIEYRDGSLLDIIREVKD
CCCCCCCHHHHEEEEEEECCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9457870 [H]