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The map label for this gene is citE

Identifier: 15673172

GI number: 15673172

Start: 1208087

End: 1209001

Strand: Direct

Name: citE

Synonym: L0040

Alternate gene names: 15673172

Gene position: 1208087-1209001 (Clockwise)

Preceding gene: 15673171

Following gene: 15673173

Centisome position: 51.07

GC content: 46.99

Gene sequence:

>915_bases
ATGGCAGTAGCAGAACGTTTACGTCGGACAATGATGTTTGTGCCTGGGAATAACCCAGCCATGATTAAGGATGCAGGAAT
TTTTGAGGCTGACTCGATTATGTTTGACTTGGAAGATGCAGTTTCTTTGGCAGAAAAAGATGCGGCGCGGGTTTTGGTCT
ATGAGGCGGTCAAAAATATTGATTTTGGTGGGGCTGAATTGGTCGTGCGAATCAATGGTTTGGACACGCCATTTTGGCAA
AAAGATGTGCGGGCCATGGTGAAAGCCGGTATCGAAGTCATCCGTGCACCAAAAGTTGAAACAGCAGCTATGATGGAAGA
GCTGGAAGTCGAAATCGAAAAAGCTGAAAAAGAATTTGGCATCGAAGTCGGCACCACGCACGTCATGGCAGCACTTGAGT
CTGCTCTTGGCGTCATGAATGCGCTGGAAATCGCGCGCTCATGTCCTGAACGCATGATGGGCATTGCCCTGTCTGGTATG
GACTACCGCGTGGACATGAAAACCAAGTCTTATCCTGATGAAGGCGAACTTTACTTTGCGCGAAATATGGTCTTGCACGC
TGCTCGTGCGGCTGGTGTGGCTGCATTTGACACGGTCTTTGGCAATGTTGATGATGAAGAAGGCTTTGTCAAGGGTGTTG
AGCTGATTCATCAGCTTGGCTTTGACGGTAAATCAGTCATCAATCCTCGTCAAATTCCTCTGGTCAACAAAGTTTATGCG
CCAACGAAGAAAGAAGTCGTTCATGCGCAACAAGTCATGGAGGCCATTGAAGAGGCTAAACAAAAGGGTTCTGGCGTCAT
TTCATTGAATGGTCAAATGGTCGACCGTCCAATCGTGTTGCAAGCTGAACGTGTGTTGATGTTGGCTAAAGCCGCAAATG
TGTTAGATGAGGGAGGAAATTACATTGAAAAATAA

Upstream 100 bases:

>100_bases
ATTGACAAAGGGGCTTTGGATTTGGTGATTAAGGCCAGAGCGATTGCGGTAGTGGAACGTGCGATTGAAGCTAAAGATTT
GAATTGGGAGGTCTTGTAAA

Downstream 100 bases:

>100_bases
AGTGAACCGTGAATTGCCAGATGAAATTTTGAAAACTACAGGTTACAAACCTTTTGAGTCAGTCGAAGTCAAGGACCTTG
TGATTGAGCGCGTGAGTGCT

Product: citrate lyase beta chain

Products: NA

Alternate protein names: Citrase beta chain; Citrate (pro-3S)-lyase subunit beta; Citryl-CoA lyase subunit [H]

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MAVAERLRRTMMFVPGNNPAMIKDAGIFEADSIMFDLEDAVSLAEKDAARVLVYEAVKNIDFGGAELVVRINGLDTPFWQ
KDVRAMVKAGIEVIRAPKVETAAMMEELEVEIEKAEKEFGIEVGTTHVMAALESALGVMNALEIARSCPERMMGIALSGM
DYRVDMKTKSYPDEGELYFARNMVLHAARAAGVAAFDTVFGNVDDEEGFVKGVELIHQLGFDGKSVINPRQIPLVNKVYA
PTKKEVVHAQQVMEAIEEAKQKGSGVISLNGQMVDRPIVLQAERVLMLAKAANVLDEGGNYIEK

Sequences:

>Translated_304_residues
MAVAERLRRTMMFVPGNNPAMIKDAGIFEADSIMFDLEDAVSLAEKDAARVLVYEAVKNIDFGGAELVVRINGLDTPFWQ
KDVRAMVKAGIEVIRAPKVETAAMMEELEVEIEKAEKEFGIEVGTTHVMAALESALGVMNALEIARSCPERMMGIALSGM
DYRVDMKTKSYPDEGELYFARNMVLHAARAAGVAAFDTVFGNVDDEEGFVKGVELIHQLGFDGKSVINPRQIPLVNKVYA
PTKKEVVHAQQVMEAIEEAKQKGSGVISLNGQMVDRPIVLQAERVLMLAKAANVLDEGGNYIEK
>Mature_303_residues
AVAERLRRTMMFVPGNNPAMIKDAGIFEADSIMFDLEDAVSLAEKDAARVLVYEAVKNIDFGGAELVVRINGLDTPFWQK
DVRAMVKAGIEVIRAPKVETAAMMEELEVEIEKAEKEFGIEVGTTHVMAALESALGVMNALEIARSCPERMMGIALSGMD
YRVDMKTKSYPDEGELYFARNMVLHAARAAGVAAFDTVFGNVDDEEGFVKGVELIHQLGFDGKSVINPRQIPLVNKVYAP
TKKEVVHAQQVMEAIEEAKQKGSGVISLNGQMVDRPIVLQAERVLMLAKAANVLDEGGNYIEK

Specific function: Represents a citryl-ACP lyase [H]

COG id: COG2301

COG function: function code G; Citrate lyase beta subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit subfamily [H]

Homologues:

Organism=Homo sapiens, GI45545437, Length=293, Percent_Identity=25.2559726962457, Blast_Score=125, Evalue=4e-29,
Organism=Escherichia coli, GI87081764, Length=292, Percent_Identity=47.945205479452, Blast_Score=265, Evalue=3e-72,
Organism=Caenorhabditis elegans, GI17557458, Length=297, Percent_Identity=27.2727272727273, Blast_Score=108, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005000
- InterPro:   IPR011206
- InterPro:   IPR006475
- InterPro:   IPR015813 [H]

Pfam domain/function: PF03328 HpcH_HpaI [H]

EC number: =4.1.3.6; =4.1.3.34 [H]

Molecular weight: Translated: 33308; Mature: 33177

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVAERLRRTMMFVPGNNPAMIKDAGIFEADSIMFDLEDAVSLAEKDAARVLVYEAVKNI
CCHHHHHHHHEEEECCCCCCEEEECCCEEHHHHEEEHHHHHHHHHHHHHHHHHHHHHHCC
DFGGAELVVRINGLDTPFWQKDVRAMVKAGIEVIRAPKVETAAMMEELEVEIEKAEKEFG
CCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHC
IEVGTTHVMAALESALGVMNALEIARSCPERMMGIALSGMDYRVDMKTKSYPDEGELYFA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEH
RNMVLHAARAAGVAAFDTVFGNVDDEEGFVKGVELIHQLGFDGKSVINPRQIPLVNKVYA
HHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCC
PTKKEVVHAQQVMEAIEEAKQKGSGVISLNGQMVDRPIVLQAERVLMLAKAANVLDEGGN
CCHHHHHHHHHHHHHHHHHHHHCCEEEEECCEEECCCEEEHHHHHHHHHHHHHHHHCCCC
YIEK
CCCC
>Mature Secondary Structure 
AVAERLRRTMMFVPGNNPAMIKDAGIFEADSIMFDLEDAVSLAEKDAARVLVYEAVKNI
CHHHHHHHHEEEECCCCCCEEEECCCEEHHHHEEEHHHHHHHHHHHHHHHHHHHHHHCC
DFGGAELVVRINGLDTPFWQKDVRAMVKAGIEVIRAPKVETAAMMEELEVEIEKAEKEFG
CCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHC
IEVGTTHVMAALESALGVMNALEIARSCPERMMGIALSGMDYRVDMKTKSYPDEGELYFA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEH
RNMVLHAARAAGVAAFDTVFGNVDDEEGFVKGVELIHQLGFDGKSVINPRQIPLVNKVYA
HHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCC
PTKKEVVHAQQVMEAIEEAKQKGSGVISLNGQMVDRPIVLQAERVLMLAKAANVLDEGGN
CCHHHHHHHHHHHHHHHHHHHHCCEEEEECCEEECCCEEEHHHHHHHHHHHHHHHHCCCC
YIEK
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9457870 [H]