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The map label for this gene is dukB

Identifier: 15673140

GI number: 15673140

Start: 1170238

End: 1170876

Strand: Direct

Name: dukB

Synonym: L169971

Alternate gene names: NA

Gene position: 1170238-1170876 (Clockwise)

Preceding gene: 15673139

Following gene: 15673141

Centisome position: 49.47

GC content: 32.24

Gene sequence:

>639_bases
TTGATCGTATTAGCAGGTACAATTGGTGCAGGGAAGTCGAGTCTAGCAAAGGCTTTAGGAGAACATTTAAAAACGGATGT
TTTTTATGAAGCGGTGGACAATAATCCTGTTCTTGATCTTTATTATCAAGACCCTCAAAAGTATGCTTTCTTGCTACAAA
TCTATTTTTTGAATAAACGTTTTGAATCAATTAAAATGGCTTATCGTCAGGATAATAACGTGCTTGACCGTTCGATTTTT
GAGGATGAACTTTTCCTAACTTTGAACTATAAAAATGGAAATGTAACAAAAACTGAATTGGAAATTTATCAAGATTTATT
AGCAAATATGTTAGAAGAACTTGATGGAATGCCCAAAAAACGTCCGGATTTATTGGTTTATATTGATGTGTCATTTGAAA
CAATGCTCTCAAGAATTGCACAACGTGGACGTTCATTTGAACAAATTGAAAATCAAGAAGGACTAAAAGATTATTATGCT
CAAGTGCATGATGAATATCCTGATTGGTATAAAAATTACAACATTTCGCCAAAATTGAGAATCGATGGTGATTCTATTGA
TTTTGTCAATAATCCTGAACATCTTGATGAAGTTTTGGGACAAATCGATAATGAGTTGAAAAAACTAGATTTGCTTTAA

Upstream 100 bases:

>100_bases
TTAATAAATAGTTGTAAATTTAAAAAATTCGGCTATAATAAAATAGATTTATAAATTCATTTCTTTCTTTTGAAGAAATG
ACGAGGAGGAAAAGACAATT

Downstream 100 bases:

>100_bases
AAAATAGTGAAATTATTATTACTGACAAGGCTGTCAGTAATTTTTATTCTTTTAAATTTACTGAGCTTTCTGTCAGTAAA
TTTTTTTCGATAAAAATGGT

Product: deoxynucleoside kinase

Products: NA

Alternate protein names: DGK; DGUO kinase; Deoxynucleoside kinase complex I F-component [H]

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MIVLAGTIGAGKSSLAKALGEHLKTDVFYEAVDNNPVLDLYYQDPQKYAFLLQIYFLNKRFESIKMAYRQDNNVLDRSIF
EDELFLTLNYKNGNVTKTELEIYQDLLANMLEELDGMPKKRPDLLVYIDVSFETMLSRIAQRGRSFEQIENQEGLKDYYA
QVHDEYPDWYKNYNISPKLRIDGDSIDFVNNPEHLDEVLGQIDNELKKLDLL

Sequences:

>Translated_212_residues
MIVLAGTIGAGKSSLAKALGEHLKTDVFYEAVDNNPVLDLYYQDPQKYAFLLQIYFLNKRFESIKMAYRQDNNVLDRSIF
EDELFLTLNYKNGNVTKTELEIYQDLLANMLEELDGMPKKRPDLLVYIDVSFETMLSRIAQRGRSFEQIENQEGLKDYYA
QVHDEYPDWYKNYNISPKLRIDGDSIDFVNNPEHLDEVLGQIDNELKKLDLL
>Mature_212_residues
MIVLAGTIGAGKSSLAKALGEHLKTDVFYEAVDNNPVLDLYYQDPQKYAFLLQIYFLNKRFESIKMAYRQDNNVLDRSIF
EDELFLTLNYKNGNVTKTELEIYQDLLANMLEELDGMPKKRPDLLVYIDVSFETMLSRIAQRGRSFEQIENQEGLKDYYA
QVHDEYPDWYKNYNISPKLRIDGDSIDFVNNPEHLDEVLGQIDNELKKLDLL

Specific function: DGK/DAK plays an essential role in generating the deoxyribonucleotide precursors, dGTP and dATP, for DNA metabolism [H]

COG id: COG1428

COG function: function code F; Deoxynucleoside kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DCK/DGK family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002624 [H]

Pfam domain/function: PF01712 dNK [H]

EC number: =2.7.1.113 [H]

Molecular weight: Translated: 24737; Mature: 24737

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVLAGTIGAGKSSLAKALGEHLKTDVFYEAVDNNPVLDLYYQDPQKYAFLLQIYFLNKR
CEEEEECCCCCHHHHHHHHHHHHHHHHHEEECCCCCEEEEEECCCHHHHHHHHHHHHHHH
FESIKMAYRQDNNVLDRSIFEDELFLTLNYKNGNVTKTELEIYQDLLANMLEELDGMPKK
HHHHHHHHHCCCCHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
RPDLLVYIDVSFETMLSRIAQRGRSFEQIENQEGLKDYYAQVHDEYPDWYKNYNISPKLR
CCCEEEEEECCHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHCCCCHHHHCCCCCCEEE
IDGDSIDFVNNPEHLDEVLGQIDNELKKLDLL
ECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIVLAGTIGAGKSSLAKALGEHLKTDVFYEAVDNNPVLDLYYQDPQKYAFLLQIYFLNKR
CEEEEECCCCCHHHHHHHHHHHHHHHHHEEECCCCCEEEEEECCCHHHHHHHHHHHHHHH
FESIKMAYRQDNNVLDRSIFEDELFLTLNYKNGNVTKTELEIYQDLLANMLEELDGMPKK
HHHHHHHHHCCCCHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
RPDLLVYIDVSFETMLSRIAQRGRSFEQIENQEGLKDYYAQVHDEYPDWYKNYNISPKLR
CCCEEEEEECCHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHCCCCHHHHCCCCCCEEE
IDGDSIDFVNNPEHLDEVLGQIDNELKKLDLL
ECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7896798; 8172906 [H]