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The map label for this gene is glyQ

Identifier: 15673077

GI number: 15673077

Start: 1101840

End: 1102793

Strand: Direct

Name: glyQ

Synonym: L101560

Alternate gene names: 15673077

Gene position: 1101840-1102793 (Clockwise)

Preceding gene: 15673076

Following gene: 15673078

Centisome position: 46.58

GC content: 38.47

Gene sequence:

>954_bases
ATGGCAAATAAAAAACTAGCATTTCAAGATATTATCTTGACCCTACAAGGCTTTTGGTCTAAACAAGGGGCAAACTTGAT
GCAAGCTTATGATAATGAAGTAGGAGCAGGAACAATGAGCCCTTACACTTTCTTGCGTTCAAACGGACCTGAACCTTGGG
GAGCCGCCTATGTGCAACCTTCACGTCGTCCTGCTGACGGTCGTTATGGTGAAAACCCAAATCGGTTGTTCCAACACCAC
CAATTCCAAGTTGTATTAAAACCATCTCCAAAAAATATCCAAGAACTTTATCTTCAAAGTTTAGCTGAACTTGGAATTGA
TGCTTTAGAGCATGATATCCGCTTTGTTGAAGATAACTGGGAAAATCCTTCAATGGGATGTGCCGGTATTGGATGGGAAG
TTTGGATTGATGGGCAAGAATGTACTCAATTTACTTATTTCCAACAAGTCGGAGGAATTGAAGTTGATTCCGTAACTTCA
GAAATCACTTATGGTTTGGAACGTATTGCGACAGTTATTCAAGAGGTTGATTCTGTTTATGACCTTGAATGGGGGAATGG
CGTAGCTTACGGAGATATTTTCAAAGAGCCTGAATACGAACATTCTAAATTTGCCTTTGAAGAATCAAACCAAGAGCTTT
TACTTAAACTTTTTGGAGAATATGAACAAGAAGCGCTTGATTTATTAGATAAAGGCTTGGTTCACCCAGCTTATGATTAT
ATTTTGAAATCTTCACATACCTTCAATTTACTTGATGCACGTGGAGCAGTTTCTGTAACTGAGCGTGCAGGCTATATGCA
TAGAGTTCGTACAATGGCACGTAAGGTAGCAAAAACTTTTATTGAAGAACGTGCAAAACTTGGTTTCCCGCTCTTAAAAG
ACGAAGCTTTACGTGAAAAATACCTTGGTAAAAAAGGAAAATATACTAAGATTGTAGAAGGAGAAGAAAAATAA

Upstream 100 bases:

>100_bases
AAAGGTGGAACCGTGCATTTGCACCCTTTGTCTCTTTTCGGATTTTTTCGAGGATTGATGAGTGTGTGAATTGCGGTTTT
TTGAATTTCGGAGGAAAATA

Downstream 100 bases:

>100_bases
TGACAAATTACTTACTTGAAATTGGTTTGGAAGAAATTCCAGCACATTTGGTGACTCCTTCAATCAATCAATTAGCCGAA
AGAATGGAAACTTTTCTTAA

Product: glycyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Glycine--tRNA ligase alpha subunit; GlyRS

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MANKKLAFQDIILTLQGFWSKQGANLMQAYDNEVGAGTMSPYTFLRSNGPEPWGAAYVQPSRRPADGRYGENPNRLFQHH
QFQVVLKPSPKNIQELYLQSLAELGIDALEHDIRFVEDNWENPSMGCAGIGWEVWIDGQECTQFTYFQQVGGIEVDSVTS
EITYGLERIATVIQEVDSVYDLEWGNGVAYGDIFKEPEYEHSKFAFEESNQELLLKLFGEYEQEALDLLDKGLVHPAYDY
ILKSSHTFNLLDARGAVSVTERAGYMHRVRTMARKVAKTFIEERAKLGFPLLKDEALREKYLGKKGKYTKIVEGEEK

Sequences:

>Translated_317_residues
MANKKLAFQDIILTLQGFWSKQGANLMQAYDNEVGAGTMSPYTFLRSNGPEPWGAAYVQPSRRPADGRYGENPNRLFQHH
QFQVVLKPSPKNIQELYLQSLAELGIDALEHDIRFVEDNWENPSMGCAGIGWEVWIDGQECTQFTYFQQVGGIEVDSVTS
EITYGLERIATVIQEVDSVYDLEWGNGVAYGDIFKEPEYEHSKFAFEESNQELLLKLFGEYEQEALDLLDKGLVHPAYDY
ILKSSHTFNLLDARGAVSVTERAGYMHRVRTMARKVAKTFIEERAKLGFPLLKDEALREKYLGKKGKYTKIVEGEEK
>Mature_316_residues
ANKKLAFQDIILTLQGFWSKQGANLMQAYDNEVGAGTMSPYTFLRSNGPEPWGAAYVQPSRRPADGRYGENPNRLFQHHQ
FQVVLKPSPKNIQELYLQSLAELGIDALEHDIRFVEDNWENPSMGCAGIGWEVWIDGQECTQFTYFQQVGGIEVDSVTSE
ITYGLERIATVIQEVDSVYDLEWGNGVAYGDIFKEPEYEHSKFAFEESNQELLLKLFGEYEQEALDLLDKGLVHPAYDYI
LKSSHTFNLLDARGAVSVTERAGYMHRVRTMARKVAKTFIEERAKLGFPLLKDEALREKYLGKKGKYTKIVEGEEK

Specific function: Unknown

COG id: COG0752

COG function: function code J; Glycyl-tRNA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Escherichia coli, GI1789983, Length=295, Percent_Identity=58.9830508474576, Blast_Score=359, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYGA_LACLA (Q9CGK1)

Other databases:

- EMBL:   AE005176
- PIR:   G86761
- RefSeq:   NP_267251.1
- ProteinModelPortal:   Q9CGK1
- SMR:   Q9CGK1
- GeneID:   1114735
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L101560
- NMPDR:   fig|272623.1.peg.1127
- HOGENOM:   HBG285316
- OMA:   CRRPTDG
- ProtClustDB:   PRK09348
- BioCyc:   LLAC272623:L101560-MONOMER
- BRENDA:   6.1.1.14
- GO:   GO:0005737
- HAMAP:   MF_00254
- InterPro:   IPR006194
- InterPro:   IPR002310
- PRINTS:   PR01044
- TIGRFAMs:   TIGR00388

Pfam domain/function: PF02091 tRNA-synt_2e

EC number: =6.1.1.14

Molecular weight: Translated: 36115; Mature: 35984

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS50861 AA_TRNA_LIGASE_II_GLYAB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANKKLAFQDIILTLQGFWSKQGANLMQAYDNEVGAGTMSPYTFLRSNGPEPWGAAYVQP
CCCCHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCCCCCCC
SRRPADGRYGENPNRLFQHHQFQVVLKPSPKNIQELYLQSLAELGIDALEHDIRFVEDNW
CCCCCCCCCCCCHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCHHHHHHHHHHHCCCC
ENPSMGCAGIGWEVWIDGQECTQFTYFQQVGGIEVDSVTSEITYGLERIATVIQEVDSVY
CCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHHHHHHHHHHHH
DLEWGNGVAYGDIFKEPEYEHSKFAFEESNQELLLKLFGEYEQEALDLLDKGLVHPAYDY
CCCCCCCCEECHHHCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
ILKSSHTFNLLDARGAVSVTERAGYMHRVRTMARKVAKTFIEERAKLGFPLLKDEALREK
HHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
YLGKKGKYTKIVEGEEK
HCCCCCCEEECCCCCCC
>Mature Secondary Structure 
ANKKLAFQDIILTLQGFWSKQGANLMQAYDNEVGAGTMSPYTFLRSNGPEPWGAAYVQP
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCCCCCCC
SRRPADGRYGENPNRLFQHHQFQVVLKPSPKNIQELYLQSLAELGIDALEHDIRFVEDNW
CCCCCCCCCCCCHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCHHHHHHHHHHHCCCC
ENPSMGCAGIGWEVWIDGQECTQFTYFQQVGGIEVDSVTSEITYGLERIATVIQEVDSVY
CCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHHHHHHHHHHHH
DLEWGNGVAYGDIFKEPEYEHSKFAFEESNQELLLKLFGEYEQEALDLLDKGLVHPAYDY
CCCCCCCCEECHHHCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
ILKSSHTFNLLDARGAVSVTERAGYMHRVRTMARKVAKTFIEERAKLGFPLLKDEALREK
HHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
YLGKKGKYTKIVEGEEK
HCCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471