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The map label for this gene is nucA

Identifier: 15673076

GI number: 15673076

Start: 1100803

End: 1101555

Strand: Direct

Name: nucA

Synonym: L100541

Alternate gene names: 15673076

Gene position: 1100803-1101555 (Clockwise)

Preceding gene: 15673075

Following gene: 15673077

Centisome position: 46.53

GC content: 28.29

Gene sequence:

>753_bases
ATGATAATGAAACTTAGCATTTTACATATAAATAATACTCATCTCACTCTTGATAAGGATTTTTCTTTAATTAATAAAAT
CAAAGAAGAAAATAAAAAAAGAGTCATAGAAACTTTAGTTTTAGGAGATGGAAATAGCATTTTTAATAACATTGAGCACA
AAAATGATGAGCAAGACCTCCTGAATACCGTTCCTTTTGATGCGACGACATTGGGAAGTCATCAATTTGATGAGGGTTCA
AAAGGAATAGTGGAAAATCTAAATAAAATAAATTTTCCAATTTTAGCCGCTAATGTTAATTTTGAAGATGATAAACTTTT
AAATCCTTTAGTAAAAGAAGGAAAATTTATTCCTTATCTCCTTAAAAATACAACATCAGGTAAGAAAATAGGAATATTTG
GTTTGACAACAATGGATATTGTTTATCGCTCACATCCGAGTGCGGAGACTATCTTTTTTAACCCTTTTGATAAGGCAGAT
TTCATAGTTAAAATATTAAAGAACCTTGGAGTTGATGTTATTATTTTATTAAGTCAACTTGGAGAAGAAATGAACCAAAT
GTTAGCTCAACAATTTTTAGAAATTGATATTATTATCGATAAACCCGTAGGGACATCAGGAAAAAAAGTTGAAAAATGCG
GAAATACACTCATTATTCAATCTGAAACTGATAACTATTCTCTTATAGAATCTGAAATCAATATTGATGACGAAGGCAAT
TTACTTTTTATTCAAGAAAATAATTATGTTTGA

Upstream 100 bases:

>100_bases
GCAAGTCATCTTTTTATTTTTAGAAAAAAAGTTTAAGACACAATATATTGTGTTTTTTGTGATAAAATATAGATATTAAA
TACTATATATAGGTTTGGTT

Downstream 100 bases:

>100_bases
ATATGATAGATAAACCAGAAAATTGATACCAAATAAGACAGAAGTAAGGTCATCAGTTTATTTTGCCTTGACAAAATGGG
AAAATAGAGCTAGAATTTAT

Product: nucleotidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MIMKLSILHINNTHLTLDKDFSLINKIKEENKKRVIETLVLGDGNSIFNNIEHKNDEQDLLNTVPFDATTLGSHQFDEGS
KGIVENLNKINFPILAANVNFEDDKLLNPLVKEGKFIPYLLKNTTSGKKIGIFGLTTMDIVYRSHPSAETIFFNPFDKAD
FIVKILKNLGVDVIILLSQLGEEMNQMLAQQFLEIDIIIDKPVGTSGKKVEKCGNTLIIQSETDNYSLIESEINIDDEGN
LLFIQENNYV

Sequences:

>Translated_250_residues
MIMKLSILHINNTHLTLDKDFSLINKIKEENKKRVIETLVLGDGNSIFNNIEHKNDEQDLLNTVPFDATTLGSHQFDEGS
KGIVENLNKINFPILAANVNFEDDKLLNPLVKEGKFIPYLLKNTTSGKKIGIFGLTTMDIVYRSHPSAETIFFNPFDKAD
FIVKILKNLGVDVIILLSQLGEEMNQMLAQQFLEIDIIIDKPVGTSGKKVEKCGNTLIIQSETDNYSLIESEINIDDEGN
LLFIQENNYV
>Mature_250_residues
MIMKLSILHINNTHLTLDKDFSLINKIKEENKKRVIETLVLGDGNSIFNNIEHKNDEQDLLNTVPFDATTLGSHQFDEGS
KGIVENLNKINFPILAANVNFEDDKLLNPLVKEGKFIPYLLKNTTSGKKIGIFGLTTMDIVYRSHPSAETIFFNPFDKAD
FIVKILKNLGVDVIILLSQLGEEMNQMLAQQFLEIDIIIDKPVGTSGKKVEKCGNTLIIQSETDNYSLIESEINIDDEGN
LLFIQENNYV

Specific function: Degradation Of External Udp-Glucose To Uridine Monophosphate And Glucose-1-Phosphate, Which Can Then Be Used By The Cell. [C]

COG id: COG0737

COG function: function code F; 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5'-nucleotidase family [H]

Homologues:

Organism=Homo sapiens, GI4505467, Length=219, Percent_Identity=26.9406392694064, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641187, Length=156, Percent_Identity=30.7692307692308, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221329836, Length=155, Percent_Identity=30.9677419354839, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28573524, Length=173, Percent_Identity=32.3699421965318, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI19922444, Length=223, Percent_Identity=28.2511210762332, Blast_Score=64, Evalue=1e-10,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008334
- InterPro:   IPR006146
- InterPro:   IPR006179
- InterPro:   IPR004843
- InterPro:   IPR006420 [H]

Pfam domain/function: PF02872 5_nucleotid_C; PF00149 Metallophos [H]

EC number: =3.1.3.5 [H]

Molecular weight: Translated: 28186; Mature: 28186

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIMKLSILHINNTHLTLDKDFSLINKIKEENKKRVIETLVLGDGNSIFNNIEHKNDEQDL
CEEEEEEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHEEECCCHHHHHCCCCCCCHHHH
LNTVPFDATTLGSHQFDEGSKGIVENLNKINFPILAANVNFEDDKLLNPLVKEGKFIPYL
HHHCCCCCEECCCCCCCCCCCHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCCCEEE
LKNTTSGKKIGIFGLTTMDIVYRSHPSAETIFFNPFDKADFIVKILKNLGVDVIILLSQL
ECCCCCCCEEEEEEEHHHHHEEECCCCCCEEEECCCCHHHHHHHHHHHCCCHHHHHHHHH
GEEMNQMLAQQFLEIDIIIDKPVGTSGKKVEKCGNTLIIQSETDNYSLIESEINIDDEGN
HHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHCCCEEEEEECCCCCEEEEEECCCCCCCC
LLFIQENNYV
EEEEECCCCC
>Mature Secondary Structure
MIMKLSILHINNTHLTLDKDFSLINKIKEENKKRVIETLVLGDGNSIFNNIEHKNDEQDL
CEEEEEEEEECCCEEEECCCHHHHHHHHHHHHHHHHHHEEECCCHHHHHCCCCCCCHHHH
LNTVPFDATTLGSHQFDEGSKGIVENLNKINFPILAANVNFEDDKLLNPLVKEGKFIPYL
HHHCCCCCEECCCCCCCCCCCHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCCCEEE
LKNTTSGKKIGIFGLTTMDIVYRSHPSAETIFFNPFDKADFIVKILKNLGVDVIILLSQL
ECCCCCCCEEEEEEEHHHHHEEECCCCCCEEEECCCCHHHHHHHHHHHCCCHHHHHHHHH
GEEMNQMLAQQFLEIDIIIDKPVGTSGKKVEKCGNTLIIQSETDNYSLIESEINIDDEGN
HHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHCCCEEEEEECCCCCEEEEEECCCCCCCC
LLFIQENNYV
EEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]