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The map label for this gene is ykhF

Identifier: 15673044

GI number: 15673044

Start: 1073504

End: 1075411

Strand: Direct

Name: ykhF

Synonym: L73239

Alternate gene names: 15673044

Gene position: 1073504-1075411 (Clockwise)

Preceding gene: 15673043

Following gene: 15673045

Centisome position: 45.38

GC content: 36.79

Gene sequence:

>1908_bases
ATGATTTTACTGCAAGGGAATGGAATTGCACGCACTTTTGGTGACGATGTTTTATTTGAAAATATCAATTTTAGTTTACA
AGACCATTCAAGAATTGCCCTAGTTGGCCGAAATGGAGCTGGTAAGTCAACCTTGCTTAAAATTATTGCTGGAGTTGAAG
AAGCGAGTCGCGGAACTGTATCCAAGACCAAAGATTTGACAATGAATTATTTAGCGCAAGATACTGGGCTGAATTCCTCA
AGGACAATATTTGCCGAAATGCTCTCTGTTTTTGATTCGCTTCGCCAAATGGAAAAACAATTGCGCCAGATGGAATTGCA
AATGGGAGAACTTGCTGGGGATGAATTGACAGCTTTGATGAAACGTTACGATGCTTTATCAGAAGAATTTCGGATGAAAA
ATGGATTTACTTATGAATCTGAAATTAAGTCTGTCTTAAATGGTTTTCGTTTTGATGATGCAATGTGGGAAAGAGAAATT
TCAAGTTTATCAGGGGGACAAAAAACACGTTTGGCTCTTGCTAAGATGTTGCTTGAAAGACCACAACTTTTGATTTTGGA
TGAACCAACTAACCACTTGGATATTGAAACTTTAGCTTGGCTTGAAAATTACCTTAAAAATTACGAAGGTAGTTTATTAA
TTGTCAGTCATGACCGCTACTTTTTGGATAAAGTGGTTAATGAAGTCTTAGAATTATCTAGAGGAGAATTGACTCGTTTT
TCTGGAAATTATTCTCGCTATGTTGAACAAAGAGAGCAAAAACTCTTGTTAGAACTCAAAAATTTTGAAAAACAACAAAA
AGAAATTGCTAAATTAGAGGACTATGTTGCCAGAAATTTAGTTCGGGCTTCGACGACTAAAATGGCGCAATCGCGTCGTA
AAAAGTTGGAGAAAATGGAGCGTTTAGACGCACCAACAAGTGATGATAAATCGGCCAATGTTACTTTTACTCCTGAAAAA
ACGTCTGGAAATGTTGTTTTAACCGTTTCAGAAGCAACGGTAGGTTATGAAGATAATCGTCTCTCTGGTCCGATTAACAT
TGACGAGCGTAAAGGTGAGTCCCTTGCTATTGTTGGACCAAATGGAGTAGGTAAGACAACATTGATTAAGTCAATTGTTG
GACAGATTCCATTTTTAGCAGGTCAAGCAAAATTGGGTGCCAATGTTACTTTGGGATATTATGACCAAGAACAAGGAAGA
TTGACAGCTTCCAATACTGTCTTAGACGAATTATGGAATGAGCATCGCTTACTTAATGAAGTTGAAATTCGCAATATGCT
TGGAGCTTTTCTTTTTAGTGGAGATGATGTAAAGAAAACGGTTGGGATGCTTTCTGGTGGTGAAAAAGCCCGTCTTTTAC
TTGCTAAATTAGCAATGGATCACGATAACTTTTTAGTTTTAGATGAACCAACAAATCACTTGGATATTGATTCACGTGAG
GTCTTGGAGAATGCTTTGATTGATTTTCCAGGAACAATCTTGTTTGTTTCTCATGACCGCTATTTCATCAATAGAGTAGC
TACCAAAGTTTTAGAAATTGCTCCCGAAGGAAGTACAGAATTTTTGGGAGATTATGATTATTATGTCGAGAAAAAAGAAG
AAGTACAAGCTGAGAGTAATTCTTCAGAAAATGGGGAGCCGATAGAAAGTTTAGCTCAACAAGATTTTACAGCTCAGAAA
GAAGCTCAAAAGAATCGACGTAAAGTAGAGCGCGAAATCAAGGCTTGTGAAGAGAAACTAGCCGATTTGGAAGCAAAAAT
TGCAGCTCTATTATTGGAAATGCAAGAAAATACCGCTGATTTTGTTAAATTAGGAGAATTACCAGCTGAAATTGACCTCT
TTAATGATGAAAAAGATGAGATAGAAATGACTCTTTTGGAAGCGATGGAAGAATTGGAAAATTTGTAA

Upstream 100 bases:

>100_bases
CCTTAAATGCTATAATAGAAGGACTGCTTTTCTATCATATGAAAAGGAAAAACGAAGTATTAAAAATATGCTTTGAGATT
TAACGAAGAGGATAAATATC

Downstream 100 bases:

>100_bases
GTGTTGTGAAGAGAATTTAGTGTAAATATGCTAAAACGCGAAGCTTGAAAGCTTTGCGTTTTTTTATCAAAAAAATTCCG
AGATTTCGGAAAAAGTCTTT

Product: ABC transporter ATP binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 635; Mature: 635

Protein sequence:

>635_residues
MILLQGNGIARTFGDDVLFENINFSLQDHSRIALVGRNGAGKSTLLKIIAGVEEASRGTVSKTKDLTMNYLAQDTGLNSS
RTIFAEMLSVFDSLRQMEKQLRQMELQMGELAGDELTALMKRYDALSEEFRMKNGFTYESEIKSVLNGFRFDDAMWEREI
SSLSGGQKTRLALAKMLLERPQLLILDEPTNHLDIETLAWLENYLKNYEGSLLIVSHDRYFLDKVVNEVLELSRGELTRF
SGNYSRYVEQREQKLLLELKNFEKQQKEIAKLEDYVARNLVRASTTKMAQSRRKKLEKMERLDAPTSDDKSANVTFTPEK
TSGNVVLTVSEATVGYEDNRLSGPINIDERKGESLAIVGPNGVGKTTLIKSIVGQIPFLAGQAKLGANVTLGYYDQEQGR
LTASNTVLDELWNEHRLLNEVEIRNMLGAFLFSGDDVKKTVGMLSGGEKARLLLAKLAMDHDNFLVLDEPTNHLDIDSRE
VLENALIDFPGTILFVSHDRYFINRVATKVLEIAPEGSTEFLGDYDYYVEKKEEVQAESNSSENGEPIESLAQQDFTAQK
EAQKNRRKVEREIKACEEKLADLEAKIAALLLEMQENTADFVKLGELPAEIDLFNDEKDEIEMTLLEAMEELENL

Sequences:

>Translated_635_residues
MILLQGNGIARTFGDDVLFENINFSLQDHSRIALVGRNGAGKSTLLKIIAGVEEASRGTVSKTKDLTMNYLAQDTGLNSS
RTIFAEMLSVFDSLRQMEKQLRQMELQMGELAGDELTALMKRYDALSEEFRMKNGFTYESEIKSVLNGFRFDDAMWEREI
SSLSGGQKTRLALAKMLLERPQLLILDEPTNHLDIETLAWLENYLKNYEGSLLIVSHDRYFLDKVVNEVLELSRGELTRF
SGNYSRYVEQREQKLLLELKNFEKQQKEIAKLEDYVARNLVRASTTKMAQSRRKKLEKMERLDAPTSDDKSANVTFTPEK
TSGNVVLTVSEATVGYEDNRLSGPINIDERKGESLAIVGPNGVGKTTLIKSIVGQIPFLAGQAKLGANVTLGYYDQEQGR
LTASNTVLDELWNEHRLLNEVEIRNMLGAFLFSGDDVKKTVGMLSGGEKARLLLAKLAMDHDNFLVLDEPTNHLDIDSRE
VLENALIDFPGTILFVSHDRYFINRVATKVLEIAPEGSTEFLGDYDYYVEKKEEVQAESNSSENGEPIESLAQQDFTAQK
EAQKNRRKVEREIKACEEKLADLEAKIAALLLEMQENTADFVKLGELPAEIDLFNDEKDEIEMTLLEAMEELENL
>Mature_635_residues
MILLQGNGIARTFGDDVLFENINFSLQDHSRIALVGRNGAGKSTLLKIIAGVEEASRGTVSKTKDLTMNYLAQDTGLNSS
RTIFAEMLSVFDSLRQMEKQLRQMELQMGELAGDELTALMKRYDALSEEFRMKNGFTYESEIKSVLNGFRFDDAMWEREI
SSLSGGQKTRLALAKMLLERPQLLILDEPTNHLDIETLAWLENYLKNYEGSLLIVSHDRYFLDKVVNEVLELSRGELTRF
SGNYSRYVEQREQKLLLELKNFEKQQKEIAKLEDYVARNLVRASTTKMAQSRRKKLEKMERLDAPTSDDKSANVTFTPEK
TSGNVVLTVSEATVGYEDNRLSGPINIDERKGESLAIVGPNGVGKTTLIKSIVGQIPFLAGQAKLGANVTLGYYDQEQGR
LTASNTVLDELWNEHRLLNEVEIRNMLGAFLFSGDDVKKTVGMLSGGEKARLLLAKLAMDHDNFLVLDEPTNHLDIDSRE
VLENALIDFPGTILFVSHDRYFINRVATKVLEIAPEGSTEFLGDYDYYVEKKEEVQAESNSSENGEPIESLAQQDFTAQK
EAQKNRRKVEREIKACEEKLADLEAKIAALLLEMQENTADFVKLGELPAEIDLFNDEKDEIEMTLLEAMEELENL

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=527, Percent_Identity=31.4990512333966, Blast_Score=244, Evalue=3e-64,
Organism=Homo sapiens, GI10947137, Length=535, Percent_Identity=31.4018691588785, Blast_Score=221, Evalue=1e-57,
Organism=Homo sapiens, GI27881506, Length=535, Percent_Identity=31.4018691588785, Blast_Score=221, Evalue=2e-57,
Organism=Homo sapiens, GI10947135, Length=538, Percent_Identity=31.0408921933086, Blast_Score=205, Evalue=1e-52,
Organism=Homo sapiens, GI69354671, Length=538, Percent_Identity=31.0408921933086, Blast_Score=205, Evalue=1e-52,
Organism=Homo sapiens, GI9961252, Length=263, Percent_Identity=27.3764258555133, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI4505771, Length=263, Percent_Identity=27.3764258555133, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI9961250, Length=263, Percent_Identity=27.3764258555133, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1789751, Length=658, Percent_Identity=31.6109422492401, Blast_Score=322, Evalue=6e-89,
Organism=Escherichia coli, GI2367384, Length=535, Percent_Identity=36.8224299065421, Blast_Score=320, Evalue=1e-88,
Organism=Escherichia coli, GI1787041, Length=542, Percent_Identity=34.3173431734317, Blast_Score=300, Evalue=1e-82,
Organism=Escherichia coli, GI1787182, Length=598, Percent_Identity=31.9397993311037, Blast_Score=267, Evalue=2e-72,
Organism=Escherichia coli, GI87081782, Length=551, Percent_Identity=22.6860254083485, Blast_Score=83, Evalue=7e-17,
Organism=Escherichia coli, GI145693107, Length=553, Percent_Identity=23.6889692585895, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI48995001, Length=512, Percent_Identity=23.4375, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789891, Length=227, Percent_Identity=25.1101321585903, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1788165, Length=215, Percent_Identity=26.046511627907, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786698, Length=243, Percent_Identity=27.5720164609054, Blast_Score=67, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17559834, Length=537, Percent_Identity=31.098696461825, Blast_Score=234, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI17555318, Length=527, Percent_Identity=28.842504743833, Blast_Score=216, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI17553372, Length=528, Percent_Identity=29.5454545454545, Blast_Score=213, Evalue=3e-55,
Organism=Saccharomyces cerevisiae, GI6320874, Length=538, Percent_Identity=30.4832713754647, Blast_Score=234, Evalue=3e-62,
Organism=Saccharomyces cerevisiae, GI6321121, Length=528, Percent_Identity=30.1136363636364, Blast_Score=216, Evalue=7e-57,
Organism=Saccharomyces cerevisiae, GI6325030, Length=398, Percent_Identity=27.6381909547739, Blast_Score=126, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6324314, Length=388, Percent_Identity=27.319587628866, Blast_Score=116, Evalue=9e-27,
Organism=Saccharomyces cerevisiae, GI6323278, Length=388, Percent_Identity=26.2886597938144, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24666836, Length=545, Percent_Identity=32.8440366972477, Blast_Score=256, Evalue=3e-68,
Organism=Drosophila melanogaster, GI24642252, Length=539, Percent_Identity=30.6122448979592, Blast_Score=239, Evalue=4e-63,
Organism=Drosophila melanogaster, GI18859989, Length=539, Percent_Identity=30.6122448979592, Blast_Score=239, Evalue=4e-63,
Organism=Drosophila melanogaster, GI24641342, Length=533, Percent_Identity=32.2701688555347, Blast_Score=233, Evalue=4e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 71682; Mature: 71682

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILLQGNGIARTFGDDVLFENINFSLQDHSRIALVGRNGAGKSTLLKIIAGVEEASRGTV
CEEECCCCCCHHCCCHHHHHCCCCEEECCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCC
SKTKDLTMNYLAQDTGLNSSRTIFAEMLSVFDSLRQMEKQLRQMELQMGELAGDELTALM
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
KRYDALSEEFRMKNGFTYESEIKSVLNGFRFDDAMWEREISSLSGGQKTRLALAKMLLER
HHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
PQLLILDEPTNHLDIETLAWLENYLKNYEGSLLIVSHDRYFLDKVVNEVLELSRGELTRF
CCEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHCCCCHHHC
SGNYSRYVEQREQKLLLELKNFEKQQKEIAKLEDYVARNLVRASTTKMAQSRRKKLEKME
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLDAPTSDDKSANVTFTPEKTSGNVVLTVSEATVGYEDNRLSGPINIDERKGESLAIVGP
HCCCCCCCCCCCCEEECCCCCCCCEEEEEECCEECCCCCCCCCCCCCCCCCCCEEEEECC
NGVGKTTLIKSIVGQIPFLAGQAKLGANVTLGYYDQEQGRLTASNTVLDELWNEHRLLNE
CCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHH
VEIRNMLGAFLFSGDDVKKTVGMLSGGEKARLLLAKLAMDHDNFLVLDEPTNHLDIDSRE
HHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHH
VLENALIDFPGTILFVSHDRYFINRVATKVLEIAPEGSTEFLGDYDYYVEKKEEVQAESN
HHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCHHHHHHHCC
SSENGEPIESLAQQDFTAQKEAQKNRRKVEREIKACEEKLADLEAKIAALLLEMQENTAD
CCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
FVKLGELPAEIDLFNDEKDEIEMTLLEAMEELENL
HHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MILLQGNGIARTFGDDVLFENINFSLQDHSRIALVGRNGAGKSTLLKIIAGVEEASRGTV
CEEECCCCCCHHCCCHHHHHCCCCEEECCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCC
SKTKDLTMNYLAQDTGLNSSRTIFAEMLSVFDSLRQMEKQLRQMELQMGELAGDELTALM
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
KRYDALSEEFRMKNGFTYESEIKSVLNGFRFDDAMWEREISSLSGGQKTRLALAKMLLER
HHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
PQLLILDEPTNHLDIETLAWLENYLKNYEGSLLIVSHDRYFLDKVVNEVLELSRGELTRF
CCEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHCCCCHHHC
SGNYSRYVEQREQKLLLELKNFEKQQKEIAKLEDYVARNLVRASTTKMAQSRRKKLEKME
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLDAPTSDDKSANVTFTPEKTSGNVVLTVSEATVGYEDNRLSGPINIDERKGESLAIVGP
HCCCCCCCCCCCCEEECCCCCCCCEEEEEECCEECCCCCCCCCCCCCCCCCCCEEEEECC
NGVGKTTLIKSIVGQIPFLAGQAKLGANVTLGYYDQEQGRLTASNTVLDELWNEHRLLNE
CCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHH
VEIRNMLGAFLFSGDDVKKTVGMLSGGEKARLLLAKLAMDHDNFLVLDEPTNHLDIDSRE
HHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHH
VLENALIDFPGTILFVSHDRYFINRVATKVLEIAPEGSTEFLGDYDYYVEKKEEVQAESN
HHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCHHHHHHHCC
SSENGEPIESLAQQDFTAQKEAQKNRRKVEREIKACEEKLADLEAKIAALLLEMQENTAD
CCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
FVKLGELPAEIDLFNDEKDEIEMTLLEAMEELENL
HHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377 [H]