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The map label for this gene is mleP

Identifier: 15672883

GI number: 15672883

Start: 923403

End: 924680

Strand: Direct

Name: mleP

Synonym: L123159

Alternate gene names: 15672883

Gene position: 923403-924680 (Clockwise)

Preceding gene: 15672882

Following gene: 15672884

Centisome position: 39.03

GC content: 36.38

Gene sequence:

>1278_bases
ATGAAAAAACTTAAAGAAACGAAAATATCGGGAATTAGTCTTCCCTTATATGCCTTTTTCGTAGCTGTCATCATAGTTGT
AACACTATTAGGAAAACTTCCACTTGATATGGTAGGGTTAACTCTCCTACTTGTAACATTAGGCCACCTATTATACTTCA
TAGGAGAAAAATTCCCTATTATGAATTCATACTTAGGTGGGGGATCTGTTTTCACTTTAATTGGTGCTACTCTATTATCT
TTCTTCCACATTGTTCCTTCAAATGTTATTGGAGCAGTTTCCAATTTTATGGGTGGAAAATTTGGATTTCTTGATTTTTA
TATAGCTGCACTTATCTGTGGATCTATTTTAGGAATGAACAGAAATCTTTTGGTTAAAGCTTCCAAGAAATTTATTCCGA
TTGCTTTAATCACTATGGTTATTGGTTTCTTCTCAGTAGGTCTTGTAGGAATGCTTATTGGTAATGGATTTGCTGATTCT
GTAATGTATGTTTCTATGCCAATGATGTCAGGTGGTATGGGAGCCGGAATTACTCCACTCTCTCAAATCTATGCAGCCGG
ATTGGCTCATGGAAACCAAGCAGCTATCTTCTCTCAACTTGCTCCAGCAGTTACTTTTGGTAATATTCTTGCGATTATTG
GTGCCTTATCTATCGCTAAAGTATTCAACAAATCTAAATATAATGGACATGGGACTCTTGTTGCAGCAACTAAAGAAGAG
TTGGCTAAACCTAAAATAAAATTAGATGCTCAACAAATCGGAACAGGAATGCTCTTTGCCTTTGCTCTTTTGATGGCTGG
TGACATCTTGAACAAATTCTTCCCTAATATTCATCAATATGCATTTATGATTATTATTGTATTTATCTTGAAAGCAACAA
ATACTGTTCCTAAAGATTTAGAAGAATCTGTTGTAATGTTTAACCAAGTGATTATGACAAACCTTACTCATGCTGTTTTG
GCAGGTATTGGTCTTGCTTTGATTGACTTGAATACTCTTGCTTCAGCATTTACATGGCAATTTGTTGTACTTTGCTTGAC
AAGTGTTGTTGTAATGGGACTTGCTAGCTGGTTCTTGGCTCGCCTCTTTGGACTTTATCCAGTCGAAACTGCCATTGGTG
CAGGGATGATCAATAATTCTATGGGTGGAACAGGTAACATTGCTGTCTTGTCTGCATCAGATAGAATGGAAATGATTGCT
TTTGCACAGATGGCTAATAGACTCTGTGGTGCAATTGTCCTTATCTTCGGTGGAATTCTTATCCGATTCTTTTATTAA

Upstream 100 bases:

>100_bases
AAGCTCAAGAACAAGGTCTTACTGAATCTAAAGAAACTGATATGGCTAAAGCAGTTCGTGATCTTAAATGGTATCCAGAG
TACTAAGGGGAATATCTTAA

Downstream 100 bases:

>100_bases
AATAACCAAAAAAACATTTTATATAAAATGTTTTTTTTTGCAAAATTAACTGATTAAGGAAATAAAATAGTTGGGACTAT
ATCGCCTATCGCATGAAGTA

Product: malate transporter

Products: NA

Alternate protein names: Citrate carrier protein; Citrate transporter [H]

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MKKLKETKISGISLPLYAFFVAVIIVVTLLGKLPLDMVGLTLLLVTLGHLLYFIGEKFPIMNSYLGGGSVFTLIGATLLS
FFHIVPSNVIGAVSNFMGGKFGFLDFYIAALICGSILGMNRNLLVKASKKFIPIALITMVIGFFSVGLVGMLIGNGFADS
VMYVSMPMMSGGMGAGITPLSQIYAAGLAHGNQAAIFSQLAPAVTFGNILAIIGALSIAKVFNKSKYNGHGTLVAATKEE
LAKPKIKLDAQQIGTGMLFAFALLMAGDILNKFFPNIHQYAFMIIIVFILKATNTVPKDLEESVVMFNQVIMTNLTHAVL
AGIGLALIDLNTLASAFTWQFVVLCLTSVVVMGLASWFLARLFGLYPVETAIGAGMINNSMGGTGNIAVLSASDRMEMIA
FAQMANRLCGAIVLIFGGILIRFFY

Sequences:

>Translated_425_residues
MKKLKETKISGISLPLYAFFVAVIIVVTLLGKLPLDMVGLTLLLVTLGHLLYFIGEKFPIMNSYLGGGSVFTLIGATLLS
FFHIVPSNVIGAVSNFMGGKFGFLDFYIAALICGSILGMNRNLLVKASKKFIPIALITMVIGFFSVGLVGMLIGNGFADS
VMYVSMPMMSGGMGAGITPLSQIYAAGLAHGNQAAIFSQLAPAVTFGNILAIIGALSIAKVFNKSKYNGHGTLVAATKEE
LAKPKIKLDAQQIGTGMLFAFALLMAGDILNKFFPNIHQYAFMIIIVFILKATNTVPKDLEESVVMFNQVIMTNLTHAVL
AGIGLALIDLNTLASAFTWQFVVLCLTSVVVMGLASWFLARLFGLYPVETAIGAGMINNSMGGTGNIAVLSASDRMEMIA
FAQMANRLCGAIVLIFGGILIRFFY
>Mature_425_residues
MKKLKETKISGISLPLYAFFVAVIIVVTLLGKLPLDMVGLTLLLVTLGHLLYFIGEKFPIMNSYLGGGSVFTLIGATLLS
FFHIVPSNVIGAVSNFMGGKFGFLDFYIAALICGSILGMNRNLLVKASKKFIPIALITMVIGFFSVGLVGMLIGNGFADS
VMYVSMPMMSGGMGAGITPLSQIYAAGLAHGNQAAIFSQLAPAVTFGNILAIIGALSIAKVFNKSKYNGHGTLVAATKEE
LAKPKIKLDAQQIGTGMLFAFALLMAGDILNKFFPNIHQYAFMIIIVFILKATNTVPKDLEESVVMFNQVIMTNLTHAVL
AGIGLALIDLNTLASAFTWQFVVLCLTSVVVMGLASWFLARLFGLYPVETAIGAGMINNSMGGTGNIAVLSASDRMEMIA
FAQMANRLCGAIVLIFGGILIRFFY

Specific function: Uptake of citrate across the boundary membrane with the concomitant uptake of a sodium ion (symport system) [H]

COG id: COG3493

COG function: function code C; Na+/citrate symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:citrate (SCF) symporter family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004679
- InterPro:   IPR018025
- InterPro:   IPR002208 [H]

Pfam domain/function: PF03390 2HCT [H]

EC number: NA

Molecular weight: Translated: 45310; Mature: 45310

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLKETKISGISLPLYAFFVAVIIVVTLLGKLPLDMVGLTLLLVTLGHLLYFIGEKFPI
CCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCH
MNSYLGGGSVFTLIGATLLSFFHIVPSNVIGAVSNFMGGKFGFLDFYIAALICGSILGMN
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC
RNLLVKASKKFIPIALITMVIGFFSVGLVGMLIGNGFADSVMYVSMPMMSGGMGAGITPL
CCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHCCCCCCCCCHH
SQIYAAGLAHGNQAAIFSQLAPAVTFGNILAIIGALSIAKVFNKSKYNGHGTLVAATKEE
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECHHH
LAKPKIKLDAQQIGTGMLFAFALLMAGDILNKFFPNIHQYAFMIIIVFILKATNTVPKDL
HCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHH
EESVVMFNQVIMTNLTHAVLAGIGLALIDLNTLASAFTWQFVVLCLTSVVVMGLASWFLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLFGLYPVETAIGAGMINNSMGGTGNIAVLSASDRMEMIAFAQMANRLCGAIVLIFGGIL
HHHCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IRFFY
HHHCC
>Mature Secondary Structure
MKKLKETKISGISLPLYAFFVAVIIVVTLLGKLPLDMVGLTLLLVTLGHLLYFIGEKFPI
CCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCH
MNSYLGGGSVFTLIGATLLSFFHIVPSNVIGAVSNFMGGKFGFLDFYIAALICGSILGMN
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC
RNLLVKASKKFIPIALITMVIGFFSVGLVGMLIGNGFADSVMYVSMPMMSGGMGAGITPL
CCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHCCCCCCCCCHH
SQIYAAGLAHGNQAAIFSQLAPAVTFGNILAIIGALSIAKVFNKSKYNGHGTLVAATKEE
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECHHH
LAKPKIKLDAQQIGTGMLFAFALLMAGDILNKFFPNIHQYAFMIIIVFILKATNTVPKDL
HCCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHH
EESVVMFNQVIMTNLTHAVLAGIGLALIDLNTLASAFTWQFVVLCLTSVVVMGLASWFLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLFGLYPVETAIGAGMINNSMGGTGNIAVLSASDRMEMIAFAQMANRLCGAIVLIFGGIL
HHHCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IRFFY
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2120190 [H]