| Definition | Lactococcus lactis subsp. lactis Il1403, complete genome. |
|---|---|
| Accession | NC_002662 |
| Length | 2,365,589 |
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The map label for this gene is ppiB
Identifier: 15672875
GI number: 15672875
Start: 914117
End: 914707
Strand: Direct
Name: ppiB
Synonym: L113864
Alternate gene names: 15672875
Gene position: 914117-914707 (Clockwise)
Preceding gene: 15672874
Following gene: 15672876
Centisome position: 38.64
GC content: 38.75
Gene sequence:
>591_bases ATGACTTACCCACAACTTGAACTTGAAAACTACAAAGGTACTACAGCAATTATCAATACAAATCATGGAAAAATGACTGT AAAATTATTTGATAATCTTGCTCCAAAAACCGTAAAAAACTTTATTGAACTTAGCAAAGAGGGGTATTATGATGGAGTAA TTTTCCACCGTATCATCAAAGATTTCATGGTTCAAGGAGGAGACCCAACAGGAACTGGGATGGGTGGTTCTTCAATCTAC GGAGAAAAATTTGAAGATGAGTTCTCAATGGACCTCTTTAATCTTCGGGGAGCTTTGTCAATGGCCAATGCTGGACCTAA TACAAACGGAAGTCAATTTTTCATTGTTCAAAATAAAAACTTGCCTTATCCTAAAGATTCACTTATCCAAGGAGGGTGGC CTGAAGAAGTAGCTGAAACATATACTGGCGGCGGAACTCCTCATCTTGATGGCCGTCACACTGTCTTTGGTCAATTGGTT GATGAAGAAAGCTATAAAGTTCTCGATGAAATTGCAGCTGTTCGTGTAGGTGCGCAAGATAAACCAGTCGATGATGTCGT TATTGAATCAGTTGAGATTATCGAGCCATAA
Upstream 100 bases:
>100_bases CTATCAGTAAAAACTGTCAGTAAAAATTACTGACAGAAATTTATTAACTTATAAAAAGAAAGGAAGGTATTTTTAGAAAT AAAAATACTAACTAAAAAAT
Downstream 100 bases:
>100_bases TATGGAGAAGAAAAGTCCTAAAATCGGTGATATTGTTGAGGTTGAAATTATTGGAATGCAAGATTATGGTGCATTTGTAA AATTTTACCTGGATAATTCA
Product: peptidyl-prolyl cis-trans isomerase
Products: NA
Alternate protein names: Phosphatase; Peptidyl-prolyl cis-trans isomerase; PPIase; Rotamase [H]
Number of amino acids: Translated: 196; Mature: 195
Protein sequence:
>196_residues MTYPQLELENYKGTTAIINTNHGKMTVKLFDNLAPKTVKNFIELSKEGYYDGVIFHRIIKDFMVQGGDPTGTGMGGSSIY GEKFEDEFSMDLFNLRGALSMANAGPNTNGSQFFIVQNKNLPYPKDSLIQGGWPEEVAETYTGGGTPHLDGRHTVFGQLV DEESYKVLDEIAAVRVGAQDKPVDDVVIESVEIIEP
Sequences:
>Translated_196_residues MTYPQLELENYKGTTAIINTNHGKMTVKLFDNLAPKTVKNFIELSKEGYYDGVIFHRIIKDFMVQGGDPTGTGMGGSSIY GEKFEDEFSMDLFNLRGALSMANAGPNTNGSQFFIVQNKNLPYPKDSLIQGGWPEEVAETYTGGGTPHLDGRHTVFGQLV DEESYKVLDEIAAVRVGAQDKPVDDVVIESVEIIEP >Mature_195_residues TYPQLELENYKGTTAIINTNHGKMTVKLFDNLAPKTVKNFIELSKEGYYDGVIFHRIIKDFMVQGGDPTGTGMGGSSIYG EKFEDEFSMDLFNLRGALSMANAGPNTNGSQFFIVQNKNLPYPKDSLIQGGWPEEVAETYTGGGTPHLDGRHTVFGQLVD EESYKVLDEIAAVRVGAQDKPVDDVVIESVEIIEP
Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]
COG id: COG0652
COG function: function code O; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PPIase cyclophilin-type domain [H]
Homologues:
Organism=Homo sapiens, GI7706339, Length=181, Percent_Identity=44.1988950276243, Blast_Score=150, Evalue=7e-37, Organism=Homo sapiens, GI19557636, Length=181, Percent_Identity=43.646408839779, Blast_Score=141, Evalue=4e-34, Organism=Homo sapiens, GI24308049, Length=195, Percent_Identity=44.6153846153846, Blast_Score=139, Evalue=1e-33, Organism=Homo sapiens, GI64276486, Length=179, Percent_Identity=38.5474860335196, Blast_Score=130, Evalue=8e-31, Organism=Homo sapiens, GI4758950, Length=178, Percent_Identity=40.4494382022472, Blast_Score=110, Evalue=6e-25, Organism=Homo sapiens, GI4505991, Length=171, Percent_Identity=41.5204678362573, Blast_Score=109, Evalue=1e-24, Organism=Homo sapiens, GI4826932, Length=150, Percent_Identity=43.3333333333333, Blast_Score=107, Evalue=6e-24, Organism=Homo sapiens, GI42560244, Length=187, Percent_Identity=39.572192513369, Blast_Score=106, Evalue=1e-23, Organism=Homo sapiens, GI22547212, Length=179, Percent_Identity=39.6648044692737, Blast_Score=105, Evalue=2e-23, Organism=Homo sapiens, GI7657473, Length=179, Percent_Identity=39.6648044692737, Blast_Score=105, Evalue=2e-23, Organism=Homo sapiens, GI22547215, Length=179, Percent_Identity=39.6648044692737, Blast_Score=105, Evalue=2e-23, Organism=Homo sapiens, GI6631100, Length=178, Percent_Identity=35.9550561797753, Blast_Score=100, Evalue=6e-22, Organism=Homo sapiens, GI10863927, Length=162, Percent_Identity=42.5925925925926, Blast_Score=100, Evalue=8e-22, Organism=Homo sapiens, GI256017253, Length=144, Percent_Identity=43.75, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI221139811, Length=144, Percent_Identity=43.75, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI256017251, Length=144, Percent_Identity=43.75, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI5454154, Length=182, Percent_Identity=39.5604395604396, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI178057341, Length=141, Percent_Identity=43.9716312056738, Blast_Score=97, Evalue=9e-21, Organism=Homo sapiens, GI209417936, Length=141, Percent_Identity=43.9716312056738, Blast_Score=96, Evalue=2e-20, Organism=Homo sapiens, GI30102944, Length=141, Percent_Identity=43.9716312056738, Blast_Score=96, Evalue=2e-20, Organism=Homo sapiens, GI219842199, Length=141, Percent_Identity=43.9716312056738, Blast_Score=96, Evalue=2e-20, Organism=Homo sapiens, GI5174637, Length=177, Percent_Identity=39.5480225988701, Blast_Score=94, Evalue=6e-20, Organism=Homo sapiens, GI310129267, Length=140, Percent_Identity=44.2857142857143, Blast_Score=92, Evalue=2e-19, Organism=Homo sapiens, GI310120620, Length=140, Percent_Identity=44.2857142857143, Blast_Score=92, Evalue=2e-19, Organism=Homo sapiens, GI45439316, Length=159, Percent_Identity=39.622641509434, Blast_Score=91, Evalue=8e-19, Organism=Homo sapiens, GI303305009, Length=159, Percent_Identity=39.622641509434, Blast_Score=91, Evalue=9e-19, Organism=Homo sapiens, GI5031987, Length=157, Percent_Identity=40.1273885350318, Blast_Score=90, Evalue=1e-18, Organism=Homo sapiens, GI310110104, Length=153, Percent_Identity=41.1764705882353, Blast_Score=90, Evalue=1e-18, Organism=Homo sapiens, GI150418007, Length=147, Percent_Identity=40.1360544217687, Blast_Score=90, Evalue=1e-18, Organism=Homo sapiens, GI169163387, Length=103, Percent_Identity=52.4271844660194, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI20911035, Length=184, Percent_Identity=30.4347826086957, Blast_Score=87, Evalue=6e-18, Organism=Homo sapiens, GI169164185, Length=99, Percent_Identity=53.5353535353535, Blast_Score=87, Evalue=9e-18, Organism=Homo sapiens, GI169163623, Length=99, Percent_Identity=53.5353535353535, Blast_Score=87, Evalue=9e-18, Organism=Homo sapiens, GI310127646, Length=141, Percent_Identity=41.1347517730496, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI310114371, Length=141, Percent_Identity=41.1347517730496, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI310119221, Length=141, Percent_Identity=41.1347517730496, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI14277126, Length=124, Percent_Identity=41.9354838709677, Blast_Score=84, Evalue=8e-17, Organism=Homo sapiens, GI27735045, Length=163, Percent_Identity=36.1963190184049, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI310132444, Length=95, Percent_Identity=53.6842105263158, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI310113152, Length=95, Percent_Identity=53.6842105263158, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI169214050, Length=153, Percent_Identity=37.9084967320261, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI239751853, Length=153, Percent_Identity=37.9084967320261, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI113428306, Length=153, Percent_Identity=37.9084967320261, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI310114540, Length=134, Percent_Identity=41.044776119403, Blast_Score=75, Evalue=4e-14, Organism=Homo sapiens, GI310127745, Length=134, Percent_Identity=41.044776119403, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI310119290, Length=134, Percent_Identity=41.044776119403, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI289803023, Length=189, Percent_Identity=31.2169312169312, Blast_Score=71, Evalue=5e-13, Organism=Escherichia coli, GI1786736, Length=186, Percent_Identity=37.6344086021505, Blast_Score=98, Evalue=3e-22, Organism=Caenorhabditis elegans, GI17539496, Length=173, Percent_Identity=45.6647398843931, Blast_Score=143, Evalue=5e-35, Organism=Caenorhabditis elegans, GI17552780, Length=172, Percent_Identity=46.5116279069767, Blast_Score=124, Evalue=4e-29, Organism=Caenorhabditis elegans, GI71980594, Length=180, Percent_Identity=38.3333333333333, Blast_Score=122, Evalue=1e-28, Organism=Caenorhabditis elegans, GI71980590, Length=170, Percent_Identity=38.8235294117647, Blast_Score=120, Evalue=4e-28, Organism=Caenorhabditis elegans, GI17506311, Length=147, Percent_Identity=44.8979591836735, Blast_Score=120, Evalue=6e-28, Organism=Caenorhabditis elegans, GI71997782, Length=144, Percent_Identity=41.6666666666667, Blast_Score=120, Evalue=6e-28, Organism=Caenorhabditis elegans, GI17532641, Length=176, Percent_Identity=40.9090909090909, Blast_Score=115, Evalue=1e-26, Organism=Caenorhabditis elegans, GI17506307, Length=174, Percent_Identity=44.2528735632184, Blast_Score=114, Evalue=4e-26, Organism=Caenorhabditis elegans, GI17551282, Length=176, Percent_Identity=40.9090909090909, Blast_Score=108, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17551284, Length=176, Percent_Identity=40.9090909090909, Blast_Score=107, Evalue=3e-24, Organism=Caenorhabditis elegans, GI17559074, Length=179, Percent_Identity=41.8994413407821, Blast_Score=106, Evalue=6e-24, Organism=Caenorhabditis elegans, GI17565860, Length=173, Percent_Identity=42.1965317919075, Blast_Score=102, Evalue=9e-23, Organism=Caenorhabditis elegans, GI17566266, Length=150, Percent_Identity=41.3333333333333, Blast_Score=100, Evalue=3e-22, Organism=Caenorhabditis elegans, GI17539498, Length=143, Percent_Identity=42.6573426573427, Blast_Score=99, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17552784, Length=185, Percent_Identity=36.2162162162162, Blast_Score=98, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17552782, Length=150, Percent_Identity=38, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17532643, Length=176, Percent_Identity=36.3636363636364, Blast_Score=93, Evalue=9e-20, Organism=Caenorhabditis elegans, GI32563659, Length=192, Percent_Identity=31.25, Blast_Score=87, Evalue=7e-18, Organism=Saccharomyces cerevisiae, GI6323562, Length=180, Percent_Identity=42.7777777777778, Blast_Score=112, Evalue=3e-26, Organism=Saccharomyces cerevisiae, GI6321848, Length=175, Percent_Identity=40.5714285714286, Blast_Score=109, Evalue=4e-25, Organism=Saccharomyces cerevisiae, GI6320359, Length=175, Percent_Identity=40.5714285714286, Blast_Score=105, Evalue=4e-24, Organism=Saccharomyces cerevisiae, GI6323246, Length=188, Percent_Identity=37.2340425531915, Blast_Score=105, Evalue=6e-24, Organism=Saccharomyces cerevisiae, GI6320510, Length=172, Percent_Identity=38.3720930232558, Blast_Score=97, Evalue=2e-21, Organism=Saccharomyces cerevisiae, GI6322492, Length=209, Percent_Identity=33.0143540669856, Blast_Score=82, Evalue=4e-17, Organism=Drosophila melanogaster, GI19922376, Length=178, Percent_Identity=43.2584269662921, Blast_Score=152, Evalue=2e-37, Organism=Drosophila melanogaster, GI17986117, Length=177, Percent_Identity=44.0677966101695, Blast_Score=141, Evalue=2e-34, Organism=Drosophila melanogaster, GI20130249, Length=172, Percent_Identity=45.3488372093023, Blast_Score=117, Evalue=6e-27, Organism=Drosophila melanogaster, GI21357249, Length=179, Percent_Identity=35.195530726257, Blast_Score=113, Evalue=9e-26, Organism=Drosophila melanogaster, GI24652460, Length=181, Percent_Identity=36.4640883977901, Blast_Score=112, Evalue=2e-25, Organism=Drosophila melanogaster, GI19922912, Length=179, Percent_Identity=44.1340782122905, Blast_Score=108, Evalue=3e-24, Organism=Drosophila melanogaster, GI24650807, Length=178, Percent_Identity=37.6404494382022, Blast_Score=104, Evalue=4e-23, Organism=Drosophila melanogaster, GI17647301, Length=146, Percent_Identity=41.7808219178082, Blast_Score=95, Evalue=3e-20, Organism=Drosophila melanogaster, GI45549139, Length=147, Percent_Identity=42.1768707482993, Blast_Score=94, Evalue=6e-20, Organism=Drosophila melanogaster, GI24664125, Length=174, Percent_Identity=39.0804597701149, Blast_Score=94, Evalue=7e-20, Organism=Drosophila melanogaster, GI21357783, Length=174, Percent_Identity=39.0804597701149, Blast_Score=94, Evalue=7e-20, Organism=Drosophila melanogaster, GI24586038, Length=185, Percent_Identity=35.1351351351351, Blast_Score=93, Evalue=1e-19, Organism=Drosophila melanogaster, GI17136360, Length=177, Percent_Identity=37.2881355932203, Blast_Score=92, Evalue=2e-19, Organism=Drosophila melanogaster, GI21355677, Length=189, Percent_Identity=31.7460317460317, Blast_Score=85, Evalue=3e-17, Organism=Drosophila melanogaster, GI24661775, Length=105, Percent_Identity=41.9047619047619, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI21355237, Length=105, Percent_Identity=41.9047619047619, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24661771, Length=105, Percent_Identity=41.9047619047619, Blast_Score=70, Evalue=1e-12,
Paralogues:
None
Copy number: 780 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR015891 - InterPro: IPR023214 - InterPro: IPR013200 - InterPro: IPR006379 - InterPro: IPR000150 - InterPro: IPR002130 [H]
Pfam domain/function: PF08282 Hydrolase_3; PF00160 Pro_isomerase [H]
EC number: =5.2.1.8 [H]
Molecular weight: Translated: 21587; Mature: 21456
Theoretical pI: Translated: 4.37; Mature: 4.37
Prosite motif: PS00170 CSA_PPIASE_1 ; PS50072 CSA_PPIASE_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 3.1 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 2.6 %Met (Mature Protein) 2.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTYPQLELENYKGTTAIINTNHGKMTVKLFDNLAPKTVKNFIELSKEGYYDGVIFHRIIK CCCCCCEECCCCCCEEEEECCCCEEEEEEHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHH DFMVQGGDPTGTGMGGSSIYGEKFEDEFSMDLFNLRGALSMANAGPNTNGSQFFIVQNKN HHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCC LPYPKDSLIQGGWPEEVAETYTGGGTPHLDGRHTVFGQLVDEESYKVLDEIAAVRVGAQD CCCCHHHHCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCC KPVDDVVIESVEIIEP CCHHHHHHHHHHHCCC >Mature Secondary Structure TYPQLELENYKGTTAIINTNHGKMTVKLFDNLAPKTVKNFIELSKEGYYDGVIFHRIIK CCCCCEECCCCCCEEEEECCCCEEEEEEHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHH DFMVQGGDPTGTGMGGSSIYGEKFEDEFSMDLFNLRGALSMANAGPNTNGSQFFIVQNKN HHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCC LPYPKDSLIQGGWPEEVAETYTGGGTPHLDGRHTVFGQLVDEESYKVLDEIAAVRVGAQD CCCCHHHHCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCC KPVDDVVIESVEIIEP CCHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA