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The map label for this gene is sdaA

Identifier: 15672813

GI number: 15672813

Start: 844122

End: 844985

Strand: Direct

Name: sdaA

Synonym: L44083

Alternate gene names: 15672813

Gene position: 844122-844985 (Clockwise)

Preceding gene: 15672812

Following gene: 15672814

Centisome position: 35.68

GC content: 42.82

Gene sequence:

>864_bases
ATGTTTAAAAATATAGAAGAATTAATCGAGGATTCTAAAAATTATTCCTCGGTCATAGAATTAATGATTGCCATTGAAAT
GGAACAAACTGGACGAAATCGTGAACAAATTTGGGAAATGATGGAACATAACCTAGAAACGATGCTTGATTCTGTTAAAA
AGGGGCTTGCTGGTAAAAAATCACTTACAGGTCTTACTGGTGGCGATGCAAAATTGATGGATGATTATATTAAATCAGGC
AAAGCACTTTCGGGTGAGCTCATCTTAGGAGCAGCTCGTGATGCGGTTGCCGTCAATGAAGTGAATGCACAAATGGGGCT
CATTTGTGCGACGCCAACTGCCGGATCAGCCGGCTGTTTGCCAGGTGTTTTAACTTCAACTATTAAAACTTTAGACTTGA
GTCATGAACAGCAAGTGGAATTTTTATTTGTAGCAGGAGCCTTTGGACTTGCGATTGCAAATAATGCAACGATTTCTGGA
GCAGAGGGTGGTTGCCAAGCAGAGGTCGGTTCTGCTTCGGCAATGGCATCAGCTGCACTCGTTTTAGCTGCTGGTGGTTC
TGCAGAACAAGCAGGCTATGCGATTGCTATTGTCTTGCAAAACATGTTAGGCTTAATTTGTGACCCTGTTGCTGGTTTGG
TTGAAATCCCTTGTGTTCACCGTAATGCAATGGGGGCGTCACAAGCAATGATTTCAGCTGATATGGCTTTGGCTGGGGTT
AAAACAGTGATTCCAGTTGACGAGGTGGTCAATACCATGTATAATGTGGGACGTTCTCTACCAGCTGCTTTTAGAGAAAC
AGCTGAGGGTGGTTTGGCCCAAACACCCACTGGACGTAAAATTATGGAAGAATTATTTGGTTAA

Upstream 100 bases:

>100_bases
GTTGATACACCAAATGTTAAGGAAGTAATTGAGGAAATGAAACTTATTCCTCGTTTGCACGCCGTTAATTTCTTTAATTA
AAAGCAGTATAGGAATAAAT

Downstream 100 bases:

>100_bases
GATTAAACTTAAGAATTCGAATGATAAAATTCGAATTTTATTTTTTAGGTTGAATACTTGACTTTTAGTGTTTACACGTG
TAAACTTATCTTATGAAAAT

Product: alpha-subuni L-serine dehydratase

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MFKNIEELIEDSKNYSSVIELMIAIEMEQTGRNREQIWEMMEHNLETMLDSVKKGLAGKKSLTGLTGGDAKLMDDYIKSG
KALSGELILGAARDAVAVNEVNAQMGLICATPTAGSAGCLPGVLTSTIKTLDLSHEQQVEFLFVAGAFGLAIANNATISG
AEGGCQAEVGSASAMASAALVLAAGGSAEQAGYAIAIVLQNMLGLICDPVAGLVEIPCVHRNAMGASQAMISADMALAGV
KTVIPVDEVVNTMYNVGRSLPAAFRETAEGGLAQTPTGRKIMEELFG

Sequences:

>Translated_287_residues
MFKNIEELIEDSKNYSSVIELMIAIEMEQTGRNREQIWEMMEHNLETMLDSVKKGLAGKKSLTGLTGGDAKLMDDYIKSG
KALSGELILGAARDAVAVNEVNAQMGLICATPTAGSAGCLPGVLTSTIKTLDLSHEQQVEFLFVAGAFGLAIANNATISG
AEGGCQAEVGSASAMASAALVLAAGGSAEQAGYAIAIVLQNMLGLICDPVAGLVEIPCVHRNAMGASQAMISADMALAGV
KTVIPVDEVVNTMYNVGRSLPAAFRETAEGGLAQTPTGRKIMEELFG
>Mature_287_residues
MFKNIEELIEDSKNYSSVIELMIAIEMEQTGRNREQIWEMMEHNLETMLDSVKKGLAGKKSLTGLTGGDAKLMDDYIKSG
KALSGELILGAARDAVAVNEVNAQMGLICATPTAGSAGCLPGVLTSTIKTLDLSHEQQVEFLFVAGAFGLAIANNATISG
AEGGCQAEVGSASAMASAALVLAAGGSAEQAGYAIAIVLQNMLGLICDPVAGLVEIPCVHRNAMGASQAMISADMALAGV
KTVIPVDEVVNTMYNVGRSLPAAFRETAEGGLAQTPTGRKIMEELFG

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1788116, Length=260, Percent_Identity=36.9230769230769, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1789161, Length=183, Percent_Identity=44.2622950819672, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI48994925, Length=183, Percent_Identity=43.1693989071038, Blast_Score=134, Evalue=5e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005130
- InterPro:   IPR004642 [H]

Pfam domain/function: PF03313 SDH_alpha [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 29786; Mature: 29786

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKNIEELIEDSKNYSSVIELMIAIEMEQTGRNREQIWEMMEHNLETMLDSVKKGLAGKK
CCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
SLTGLTGGDAKLMDDYIKSGKALSGELILGAARDAVAVNEVNAQMGLICATPTAGSAGCL
CCCCCCCCCHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHCCCEEEEEECCCCCCCCCH
PGVLTSTIKTLDLSHEQQVEFLFVAGAFGLAIANNATISGAEGGCQAEVGSASAMASAAL
HHHHHHHHHHHCCCCCCCEEEEEEECHHHHHEECCCEECCCCCCCCCCCCCHHHHHHHHH
VLAAGGSAEQAGYAIAIVLQNMLGLICDPVAGLVEIPCVHRNAMGASQAMISADMALAGV
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHHH
KTVIPVDEVVNTMYNVGRSLPAAFRETAEGGLAQTPTGRKIMEELFG
HHHCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCHHHHHHHCC
>Mature Secondary Structure
MFKNIEELIEDSKNYSSVIELMIAIEMEQTGRNREQIWEMMEHNLETMLDSVKKGLAGKK
CCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
SLTGLTGGDAKLMDDYIKSGKALSGELILGAARDAVAVNEVNAQMGLICATPTAGSAGCL
CCCCCCCCCHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHCCCEEEEEECCCCCCCCCH
PGVLTSTIKTLDLSHEQQVEFLFVAGAFGLAIANNATISGAEGGCQAEVGSASAMASAAL
HHHHHHHHHHHCCCCCCCEEEEEEECHHHHHEECCCEECCCCCCCCCCCCCHHHHHHHHH
VLAAGGSAEQAGYAIAIVLQNMLGLICDPVAGLVEIPCVHRNAMGASQAMISADMALAGV
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHHH
KTVIPVDEVVNTMYNVGRSLPAAFRETAEGGLAQTPTGRKIMEELFG
HHHCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]