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The map label for this gene is copR

Identifier: 15672814

GI number: 15672814

Start: 845106

End: 845561

Strand: Direct

Name: copR

Synonym: L45109

Alternate gene names: 15672814

Gene position: 845106-845561 (Clockwise)

Preceding gene: 15672813

Following gene: 15672815

Centisome position: 35.72

GC content: 36.4

Gene sequence:

>456_bases
ATGAACGAAGTAGAATTTAATGTATCAAATGCCGAATTAATCGTTATGCGTGTAATTTGGTCTCTGGGAGAAGCGCGAGT
TGATGAAATTTATGCGCAAATCCCCCAAGAATTAGAATGGTCATTGGCCACTGTTAAGACTTTACTTGGTCGACTGGTAA
AAAAAGAAATGCTTTCTACCGAAAAAGAAGGAAGAAAATTTGTTTATCGTCCATTGATGGAAGAATGTACGGCTATAAAT
TTAATGGCCGATGGTCTGATCCAAAAAGTTTGTGAAACGAAACATGTCAATGTTTTGCAAGAGATGATTGAAAAATCGAC
TTTGACGGCAAAGGATATTGAACTTTTGCAAGAATCACTTAATGCCAAAGAAGTGGTAGGACAAAAACATTGTAATTGCT
TAGAAACAAGTGGACTTTGTGCTTGCAAACATGAACATGAGCAGATTTCTGCTTAA

Upstream 100 bases:

>100_bases
ATGATAAAATTCGAATTTTATTTTTTAGGTTGAATACTTGACTTTTAGTGTTTACACGTGTAAACTTATCTTATGAAAAT
GAATCGGGAAAGGAGAAAAA

Downstream 100 bases:

>100_bases
AAAGGAGAGTATAAAATGAAAGAAACTTTAAAAATTGAGGGAATGACTTGTGACCACTGTGTAATGCATGTGACAAATGC
TTTGGAAGCTATTGATGGTG

Product: transcription regulator

Products: NA

Alternate protein names: CopAB ATPases metal-fist type repressor [H]

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MNEVEFNVSNAELIVMRVIWSLGEARVDEIYAQIPQELEWSLATVKTLLGRLVKKEMLSTEKEGRKFVYRPLMEECTAIN
LMADGLIQKVCETKHVNVLQEMIEKSTLTAKDIELLQESLNAKEVVGQKHCNCLETSGLCACKHEHEQISA

Sequences:

>Translated_151_residues
MNEVEFNVSNAELIVMRVIWSLGEARVDEIYAQIPQELEWSLATVKTLLGRLVKKEMLSTEKEGRKFVYRPLMEECTAIN
LMADGLIQKVCETKHVNVLQEMIEKSTLTAKDIELLQESLNAKEVVGQKHCNCLETSGLCACKHEHEQISA
>Mature_151_residues
MNEVEFNVSNAELIVMRVIWSLGEARVDEIYAQIPQELEWSLATVKTLLGRLVKKEMLSTEKEGRKFVYRPLMEECTAIN
LMADGLIQKVCETKHVNVLQEMIEKSTLTAKDIELLQESLNAKEVVGQKHCNCLETSGLCACKHEHEQISA

Specific function: Acts as a copper responsive repressor. Binds to DNA in complex with Zn(2+), repressing the transcription of the copYZAB operon. Exchange of the bound zinc by two copper ions delivered by CopZ Cu(1+)-bound form causes release of CopY from the promoter, lea

COG id: COG3682

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BlaI transcriptional regulatory family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014071
- InterPro:   IPR005650
- InterPro:   IPR011991 [H]

Pfam domain/function: PF03965 Pencillinase_R [H]

EC number: NA

Molecular weight: Translated: 17134; Mature: 17134

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
4.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
7.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEVEFNVSNAELIVMRVIWSLGEARVDEIYAQIPQELEWSLATVKTLLGRLVKKEMLST
CCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
EKEGRKFVYRPLMEECTAINLMADGLIQKVCETKHVNVLQEMIEKSTLTAKDIELLQESL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHC
NAKEVVGQKHCNCLETSGLCACKHEHEQISA
CHHHHHHHHHCCHHCCCCCCHHCCCHHHCCC
>Mature Secondary Structure
MNEVEFNVSNAELIVMRVIWSLGEARVDEIYAQIPQELEWSLATVKTLLGRLVKKEMLST
CCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
EKEGRKFVYRPLMEECTAINLMADGLIQKVCETKHVNVLQEMIEKSTLTAKDIELLQESL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHC
NAKEVVGQKHCNCLETSGLCACKHEHEQISA
CHHHHHHHHHCCHHCCCCCCHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7876197 [H]