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The map label for this gene is argB

Identifier: 15672782

GI number: 15672782

Start: 807408

End: 808259

Strand: Direct

Name: argB

Synonym: L0107

Alternate gene names: 15672782

Gene position: 807408-808259 (Clockwise)

Preceding gene: 15672781

Following gene: 15672783

Centisome position: 34.13

GC content: 37.56

Gene sequence:

>852_bases
ATGAGAGATTCACAAAACACAGCTCAGACTTTGACCGAAAGTCTCAAATATTTTCTGAAATATCGTGACCAAACGGTTGT
CATTAAATATGGTGGCAATGCAATGATTGATGAAAAAGTGAAAGAAAGTATTCTAAAAGATATTTTATTACTTAAAACGG
TGGGAATTAAAGTAGTTTTGGTTCATGGCGGCGGACCTGCGATTGGAGAATTACTTGAAAAATATGAGCAAAAAAGCCAA
TTTGTTCAAGGTTTGCGCGTGACAGATAAGAAAACAGCTCAATTAGCACTGACAGCTTTAGCTGGAAAAGTAAATAAAAG
TTTGGTTCAAGATATCATTCGTTTAGGTGGCAATGCGATTGGCGTTTCAGGAATTGATGGTAAATTGATAGAAGCCAAAC
CTATTTCTGAAGATTTAGACTATGTTGGAGAAATTACAGCGATTCATCCGGAAATCATTGAGCGTATCAATCAAACGGAT
GCTGTTCCCGTCATTGCTTCGGCCGGCATTGGTCTTGATGGTGAAATTTATAATGTCAATGCTGATACCGCAGCCAGTCG
AATTGCCGGTGCATTGAGTGCTGAACAATTTATTTTATTAAGCGATGTTCGTGGCTTATATGGCAATTTTCCTGACGAGG
AGTCATTTATTGATGAAATCAATCTGACCAATCTAGAAAAGTTAGTCAAAGAGAAAAAAATCACTGACAGAATGATTCCA
AAGATTGAAGCCATTAAATATGCCATGTTTGAAGGATTGGGTCAGGCTGTTTTATTAGATGGCCGTGTTCCGCACGCCTT
ATTATTGGAATTATTTACTGACAAAGGGCAAGGGACAATGATAAATCATTGA

Upstream 100 bases:

>100_bases
TAGCCTTGTCAGCTGGTCATGATGTCATTCGCCTGCTTCCACCACTTGTCATGACGAAAGTAGAACTGCAAAAAGGAGCA
GAGCTATTGGAGAAAATTTT

Downstream 100 bases:

>100_bases
TAATTTAAGCAAATAAGAGGAGAGAGAATGTTTCAAGGAAGAAGTTTTTTAAAAGAAATAGATTTTAGTAAAGATGAATT
GTTATATCTGATTGATTTTG

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MRDSQNTAQTLTESLKYFLKYRDQTVVIKYGGNAMIDEKVKESILKDILLLKTVGIKVVLVHGGGPAIGELLEKYEQKSQ
FVQGLRVTDKKTAQLALTALAGKVNKSLVQDIIRLGGNAIGVSGIDGKLIEAKPISEDLDYVGEITAIHPEIIERINQTD
AVPVIASAGIGLDGEIYNVNADTAASRIAGALSAEQFILLSDVRGLYGNFPDEESFIDEINLTNLEKLVKEKKITDRMIP
KIEAIKYAMFEGLGQAVLLDGRVPHALLLELFTDKGQGTMINH

Sequences:

>Translated_283_residues
MRDSQNTAQTLTESLKYFLKYRDQTVVIKYGGNAMIDEKVKESILKDILLLKTVGIKVVLVHGGGPAIGELLEKYEQKSQ
FVQGLRVTDKKTAQLALTALAGKVNKSLVQDIIRLGGNAIGVSGIDGKLIEAKPISEDLDYVGEITAIHPEIIERINQTD
AVPVIASAGIGLDGEIYNVNADTAASRIAGALSAEQFILLSDVRGLYGNFPDEESFIDEINLTNLEKLVKEKKITDRMIP
KIEAIKYAMFEGLGQAVLLDGRVPHALLLELFTDKGQGTMINH
>Mature_283_residues
MRDSQNTAQTLTESLKYFLKYRDQTVVIKYGGNAMIDEKVKESILKDILLLKTVGIKVVLVHGGGPAIGELLEKYEQKSQ
FVQGLRVTDKKTAQLALTALAGKVNKSLVQDIIRLGGNAIGVSGIDGKLIEAKPISEDLDYVGEITAIHPEIIERINQTD
AVPVIASAGIGLDGEIYNVNADTAASRIAGALSAEQFILLSDVRGLYGNFPDEESFIDEINLTNLEKLVKEKKITDRMIP
KIEAIKYAMFEGLGQAVLLDGRVPHALLLELFTDKGQGTMINH

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI1789181, Length=284, Percent_Identity=27.8169014084507, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI145693208, Length=220, Percent_Identity=31.3636363636364, Blast_Score=79, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6320913, Length=289, Percent_Identity=27.681660899654, Blast_Score=76, Evalue=5e-15,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ARGB_LACLA (Q9CHD2)

Other databases:

- EMBL:   AE005176
- PIR:   H86724
- RefSeq:   NP_266956.1
- ProteinModelPortal:   Q9CHD2
- SMR:   Q9CHD2
- GeneID:   1114427
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L0107
- NMPDR:   fig|272623.1.peg.820
- HOGENOM:   HBG497643
- OMA:   MDIVEMV
- ProtClustDB:   PRK00942
- BioCyc:   LLAC272623:L0107-MONOMER
- BRENDA:   2.7.2.8
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR001057
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- PRINTS:   PR00474
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 30846; Mature: 30846

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: BINDING 86-86 BINDING 178-178

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDSQNTAQTLTESLKYFLKYRDQTVVIKYGGNAMIDEKVKESILKDILLLKTVGIKVVL
CCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEEEE
VHGGGPAIGELLEKYEQKSQFVQGLRVTDKKTAQLALTALAGKVNKSLVQDIIRLGGNAI
EECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
GVSGIDGKLIEAKPISEDLDYVGEITAIHPEIIERINQTDAVPVIASAGIGLDGEIYNVN
EECCCCCCEEECCCCHHHHHHHHHHHEECHHHHHHCCCCCCCCCCEECCCCCCCEEEECC
ADTAASRIAGALSAEQFILLSDVRGLYGNFPDEESFIDEINLTNLEKLVKEKKITDRMIP
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHH
KIEAIKYAMFEGLGQAVLLDGRVPHALLLELFTDKGQGTMINH
HHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MRDSQNTAQTLTESLKYFLKYRDQTVVIKYGGNAMIDEKVKESILKDILLLKTVGIKVVL
CCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEEEE
VHGGGPAIGELLEKYEQKSQFVQGLRVTDKKTAQLALTALAGKVNKSLVQDIIRLGGNAI
EECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
GVSGIDGKLIEAKPISEDLDYVGEITAIHPEIIERINQTDAVPVIASAGIGLDGEIYNVN
EECCCCCCEEECCCCHHHHHHHHHHHEECHHHHHHCCCCCCCCCCEECCCCCCCEEEECC
ADTAASRIAGALSAEQFILLSDVRGLYGNFPDEESFIDEINLTNLEKLVKEKKITDRMIP
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHH
KIEAIKYAMFEGLGQAVLLDGRVPHALLLELFTDKGQGTMINH
HHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471