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The map label for this gene is argD

Identifier: 15672781

GI number: 15672781

Start: 806278

End: 807411

Strand: Direct

Name: argD

Synonym: L0106

Alternate gene names: 15672781

Gene position: 806278-807411 (Clockwise)

Preceding gene: 15672780

Following gene: 15672782

Centisome position: 34.08

GC content: 35.8

Gene sequence:

>1134_bases
ATGACAAATTTATTTGAAAATTATGGTCGCCTACCATTTAGCTTAATCAAAGGAGAAGATCAATATTTATTTGATGACAG
GGGAAATAAGTATTTAGATTTCACAAGTGGGATTGGGGTCATGAATTTAGGATATAGTTTTGAAAAGGGAAAAGTGGCGG
TGAAAGCTCAATTAGACAGCCTGTCTCATCTTTCAAATCTTTATCAAAATCCTTTGCAAGAAGATGTGGCTGAAAAGTTA
AGTCAAAATCATTCATATAAAGCTTTTTTTTGTAATTCTGGGACTGAAGCTAATGAAGCAGCTTTAAAATTAACTCATCT
CATCAAAAAAGATCAGAAAATTTTGGCGTTTACAGATGGCTTTCATGGTCGTACTTTTGGTGCTATGAGTGCAACCATGC
AAGAAAAAATCCAAGCAGGATTTTCGCCTTTATTACCAAATTTTGTGGCTAGTCCTTTTAATGATGTGGTAGCACTTGAG
CAAATTCTTGAAAAAGAAAAAATTGGCGCGATTATTTTTGAAATTATTCAGGGTGAGGGTGGCGTTTTACCAATTTCTCC
AGATTTTGTTGAAGCTCTAAAAAGTTGTCAGCAAAAAGGAATTTTACTGATTATTGATGAAATTCAAACTGGAATTGGTC
GAACTGGAAAATTATTTGCTTTTGAACATTTTGATTTTGAGCCGGATATTTTTACCTTGGCAAAAGCATTGGCGAATGGG
ATTCCTACAGGTGCGATGCTCGCTAAGAATAAATATGCCAGTTATTTTTCAGCAGGAAAGCATGGCTCAACATTTGGTGG
GAATCCTTTAGCTATGGCTTCGGCTAATGAAGTTTTAAAAGAAATTGACAGTGACTTTTTAGAAAAAGTGACTGACAAAG
GTATTTTTTTCTTAAAATTACTGACAGAAAAGCTGTCAGTAAAAGCGACGGTTAAGTCCATCAGAGGTTTGGGATTGATG
ATTGGAATTCAATTAACTGACGAGAAAAAAGTTCCAGAAGTTCTTGCTTTACTGCGTGAAAATGGTCTCTTAGCCTTGTC
AGCTGGTCATGATGTCATTCGCCTGCTTCCACCACTTGTCATGACGAAAGTAGAACTGCAAAAAGGAGCAGAGCTATTGG
AGAAAATTTTATGA

Upstream 100 bases:

>100_bases
CTTGAATGCTGGAAGTGGCTTGGGTCAGGCTTGGGGCTGTGATTTGACTTATAAATATGTCGAAATTAATGCTTTATATA
CAAGTTAAGAAGGAGAAAAA

Downstream 100 bases:

>100_bases
GAGATTCACAAAACACAGCTCAGACTTTGACCGAAAGTCTCAAATATTTTCTGAAATATCGTGACCAAACGGTTGTCATT
AAATATGGTGGCAATGCAAT

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MTNLFENYGRLPFSLIKGEDQYLFDDRGNKYLDFTSGIGVMNLGYSFEKGKVAVKAQLDSLSHLSNLYQNPLQEDVAEKL
SQNHSYKAFFCNSGTEANEAALKLTHLIKKDQKILAFTDGFHGRTFGAMSATMQEKIQAGFSPLLPNFVASPFNDVVALE
QILEKEKIGAIIFEIIQGEGGVLPISPDFVEALKSCQQKGILLIIDEIQTGIGRTGKLFAFEHFDFEPDIFTLAKALANG
IPTGAMLAKNKYASYFSAGKHGSTFGGNPLAMASANEVLKEIDSDFLEKVTDKGIFFLKLLTEKLSVKATVKSIRGLGLM
IGIQLTDEKKVPEVLALLRENGLLALSAGHDVIRLLPPLVMTKVELQKGAELLEKIL

Sequences:

>Translated_377_residues
MTNLFENYGRLPFSLIKGEDQYLFDDRGNKYLDFTSGIGVMNLGYSFEKGKVAVKAQLDSLSHLSNLYQNPLQEDVAEKL
SQNHSYKAFFCNSGTEANEAALKLTHLIKKDQKILAFTDGFHGRTFGAMSATMQEKIQAGFSPLLPNFVASPFNDVVALE
QILEKEKIGAIIFEIIQGEGGVLPISPDFVEALKSCQQKGILLIIDEIQTGIGRTGKLFAFEHFDFEPDIFTLAKALANG
IPTGAMLAKNKYASYFSAGKHGSTFGGNPLAMASANEVLKEIDSDFLEKVTDKGIFFLKLLTEKLSVKATVKSIRGLGLM
IGIQLTDEKKVPEVLALLRENGLLALSAGHDVIRLLPPLVMTKVELQKGAELLEKIL
>Mature_376_residues
TNLFENYGRLPFSLIKGEDQYLFDDRGNKYLDFTSGIGVMNLGYSFEKGKVAVKAQLDSLSHLSNLYQNPLQEDVAEKLS
QNHSYKAFFCNSGTEANEAALKLTHLIKKDQKILAFTDGFHGRTFGAMSATMQEKIQAGFSPLLPNFVASPFNDVVALEQ
ILEKEKIGAIIFEIIQGEGGVLPISPDFVEALKSCQQKGILLIIDEIQTGIGRTGKLFAFEHFDFEPDIFTLAKALANGI
PTGAMLAKNKYASYFSAGKHGSTFGGNPLAMASANEVLKEIDSDFLEKVTDKGIFFLKLLTEKLSVKATVKSIRGLGLMI
GIQLTDEKKVPEVLALLRENGLLALSAGHDVIRLLPPLVMTKVELQKGAELLEKIL

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily

Homologues:

Organism=Homo sapiens, GI4557809, Length=385, Percent_Identity=35.0649350649351, Blast_Score=214, Evalue=2e-55,
Organism=Homo sapiens, GI284507298, Length=298, Percent_Identity=35.9060402684564, Blast_Score=172, Evalue=5e-43,
Organism=Homo sapiens, GI13994255, Length=425, Percent_Identity=28.7058823529412, Blast_Score=145, Evalue=9e-35,
Organism=Homo sapiens, GI37574042, Length=410, Percent_Identity=27.3170731707317, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI226442705, Length=411, Percent_Identity=27.2506082725061, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI24119277, Length=408, Percent_Identity=25.9803921568627, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI226442709, Length=351, Percent_Identity=27.9202279202279, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI188536080, Length=411, Percent_Identity=25.3041362530414, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI38679950, Length=411, Percent_Identity=25.3041362530414, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI38679946, Length=411, Percent_Identity=25.3041362530414, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1788044, Length=373, Percent_Identity=36.9973190348526, Blast_Score=240, Evalue=1e-64,
Organism=Escherichia coli, GI1789759, Length=375, Percent_Identity=37.3333333333333, Blast_Score=237, Evalue=1e-63,
Organism=Escherichia coli, GI1789016, Length=397, Percent_Identity=32.7455919395466, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI145693181, Length=375, Percent_Identity=34.4, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1787560, Length=393, Percent_Identity=32.3155216284987, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1786991, Length=389, Percent_Identity=30.3341902313625, Blast_Score=138, Evalue=7e-34,
Organism=Escherichia coli, GI1786349, Length=355, Percent_Identity=27.3239436619718, Blast_Score=99, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI25144271, Length=388, Percent_Identity=33.2474226804124, Blast_Score=211, Evalue=6e-55,
Organism=Caenorhabditis elegans, GI25144274, Length=380, Percent_Identity=30, Blast_Score=175, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI32564660, Length=421, Percent_Identity=30.6413301662708, Blast_Score=165, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI71992977, Length=422, Percent_Identity=27.4881516587678, Blast_Score=130, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI17541228, Length=429, Percent_Identity=26.1072261072261, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI71981843, Length=197, Percent_Identity=27.4111675126904, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6324432, Length=387, Percent_Identity=39.2764857881137, Blast_Score=244, Evalue=2e-65,
Organism=Saccharomyces cerevisiae, GI6323470, Length=403, Percent_Identity=34.2431761786601, Blast_Score=200, Evalue=3e-52,
Organism=Saccharomyces cerevisiae, GI6324386, Length=353, Percent_Identity=28.328611898017, Blast_Score=102, Evalue=9e-23,
Organism=Saccharomyces cerevisiae, GI6321456, Length=406, Percent_Identity=25.8620689655172, Blast_Score=76, Evalue=8e-15,
Organism=Drosophila melanogaster, GI21357415, Length=388, Percent_Identity=34.5360824742268, Blast_Score=202, Evalue=3e-52,
Organism=Drosophila melanogaster, GI161085790, Length=428, Percent_Identity=28.7383177570093, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI28574759, Length=426, Percent_Identity=28.4037558685446, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI21356575, Length=401, Percent_Identity=27.6807980049875, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI281366494, Length=293, Percent_Identity=29.3515358361775, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24667139, Length=293, Percent_Identity=29.3515358361775, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24667143, Length=293, Percent_Identity=29.3515358361775, Blast_Score=105, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGD_LACLA (Q9CHD3)

Other databases:

- EMBL:   AE005176
- PIR:   G86724
- RefSeq:   NP_266955.1
- ProteinModelPortal:   Q9CHD3
- GeneID:   1114426
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L0106
- NMPDR:   fig|272623.1.peg.819
- HOGENOM:   HBG725944
- OMA:   PKAREGF
- ProtClustDB:   PRK02936
- BioCyc:   LLAC272623:L0106-MONOMER
- BRENDA:   2.6.1.11
- GO:   GO:0005737
- HAMAP:   MF_01107
- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- PANTHER:   PTHR11986
- PANTHER:   PTHR11986:SF19
- TIGRFAMs:   TIGR00707

Pfam domain/function: PF00202 Aminotran_3; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.6.1.11

Molecular weight: Translated: 41328; Mature: 41197

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: BINDING 121-121 BINDING 124-124 BINDING 263-263 BINDING 264-264

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNLFENYGRLPFSLIKGEDQYLFDDRGNKYLDFTSGIGVMNLGYSFEKGKVAVKAQLDS
CCCCHHHHCCCCEEEECCCCCEEECCCCCEEEEECCCCCEEECCCCCCCCCEEEEHHHHH
LSHLSNLYQNPLQEDVAEKLSQNHSYKAFFCNSGTEANEAALKLTHLIKKDQKILAFTDG
HHHHHHHHHCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEECC
FHGRTFGAMSATMQEKIQAGFSPLLPNFVASPFNDVVALEQILEKEKIGAIIFEIIQGEG
CCCCCHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GVLPISPDFVEALKSCQQKGILLIIDEIQTGIGRTGKLFAFEHFDFEPDIFTLAKALANG
CEECCCHHHHHHHHHHHHCCEEEEEEHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHCC
IPTGAMLAKNKYASYFSAGKHGSTFGGNPLAMASANEVLKEIDSDFLEKVTDKGIFFLKL
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LTEKLSVKATVKSIRGLGLMIGIQLTDEKKVPEVLALLRENGLLALSAGHDVIRLLPPLV
HHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHH
MTKVELQKGAELLEKIL
HHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
TNLFENYGRLPFSLIKGEDQYLFDDRGNKYLDFTSGIGVMNLGYSFEKGKVAVKAQLDS
CCCHHHHCCCCEEEECCCCCEEECCCCCEEEEECCCCCEEECCCCCCCCCEEEEHHHHH
LSHLSNLYQNPLQEDVAEKLSQNHSYKAFFCNSGTEANEAALKLTHLIKKDQKILAFTDG
HHHHHHHHHCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEECC
FHGRTFGAMSATMQEKIQAGFSPLLPNFVASPFNDVVALEQILEKEKIGAIIFEIIQGEG
CCCCCHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GVLPISPDFVEALKSCQQKGILLIIDEIQTGIGRTGKLFAFEHFDFEPDIFTLAKALANG
CEECCCHHHHHHHHHHHHCCEEEEEEHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHCC
IPTGAMLAKNKYASYFSAGKHGSTFGGNPLAMASANEVLKEIDSDFLEKVTDKGIFFLKL
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
LTEKLSVKATVKSIRGLGLMIGIQLTDEKKVPEVLALLRENGLLALSAGHDVIRLLPPLV
HHHHHHHHHHHHHHCCCEEEEEEEECCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHH
MTKVELQKGAELLEKIL
HHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471