Click here to switch to the map view.

The map label for this gene is argC

Identifier: 15672779

GI number: 15672779

Start: 804041

End: 805063

Strand: Direct

Name: argC

Synonym: L0104

Alternate gene names: 15672779

Gene position: 804041-805063 (Clockwise)

Preceding gene: 15672778

Following gene: 15672780

Centisome position: 33.99

GC content: 34.51

Gene sequence:

>1023_bases
ATGAAAAAAGTAGCAATTGTCGGAATTAGAGGTTATAGCGGCTTAGAACTGTTCCGAATTTTCTATTATCATCCAGAAGT
AGAAGTAACAAAAATATATGCAACAAGTCATTATGGAGAAAAATTATCAGAACACTTTCCGCAACTTGAAGGCTTGACTG
ACTTGACTATCAGTGAATTTAATGAAGAAGAAATTATGGCAGAATGTGATGCAGTTTTCTTTGCAACCTCAGCGGGTGTT
AGTCAAAAATTAGCTTTAACGTTTATTGATAATAATTTTCCTGTCATTGATTTATCAGGAGATTTTCGATTAGCTGATTT
AGAAATATACAATAAATGGTATAAAAATACAAATTTAAAAAATGAATATTTATTAAGCGGTCAATATAATCTGGCAGACA
TTGGTCAAGCAAAAGCTAACTATATAGCGAATCCAGGTTGCTATGCAACAGCCACACTACTTGCACTTTATCCGTTAGTT
AAAAATAAGATGATTGATTTAGACTCAATCATTGTGGATGCCAAGTCAGGACTTTCGGGAGCCGGAAAAGGTCTGTCTGA
CGCGAGTCATTTTGTGAATGTTGTCGATAATATGTCCATGTATAAAATCAATAGTCATCAACATATTCCAGAAATTGCTC
AACAATTGAAGATTTGGAATTCAAATTTTCAAGCCTTGCAATTTTCAACTTCTTTAATTCCTGTGAGTCGAGGGATTTTT
GTTAGTAGCTATGCAAAAGTTGCAGCTGATTTTGATTTTGAAACGATAAAAAATGCTTATGAACAGGTCTATGCGACAAA
AAACTTTGTCAGAATTCGACGACAAATGCCCCACCTCTCAGATGTGATTGGGACCAATTTTTGCGATATTGGATTAGCTT
ATAATCCAGTGACAAATGTTTTGTCAGTTGTTTCGGTGATTGACAATCTTATGAAAGGGGCTGCCGGACAAGCAGTACAA
AATTTTAATCAGTTATTTGGCTACGATGAAAGTTTAGGCTTGAAATTTATGCCAAGTCTTTAG

Upstream 100 bases:

>100_bases
TCTCTTTTTTTGTTTAAAAAAGTATAATAATACATAAAATTCTTGACAAATAAAAAATAGAGTAGTATAGTGTATAAAAA
TACATAGAAAGTGTGTAAAT

Downstream 100 bases:

>100_bases
AAGAGGAAGAAATGAAAGAAATAAAAGGGACAATTGCAAGTCCAAAGGGATTTTTGGCAGATGCTGTTCATGCACAATTA
AAATATAAAAACTTAGATTT

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MKKVAIVGIRGYSGLELFRIFYYHPEVEVTKIYATSHYGEKLSEHFPQLEGLTDLTISEFNEEEIMAECDAVFFATSAGV
SQKLALTFIDNNFPVIDLSGDFRLADLEIYNKWYKNTNLKNEYLLSGQYNLADIGQAKANYIANPGCYATATLLALYPLV
KNKMIDLDSIIVDAKSGLSGAGKGLSDASHFVNVVDNMSMYKINSHQHIPEIAQQLKIWNSNFQALQFSTSLIPVSRGIF
VSSYAKVAADFDFETIKNAYEQVYATKNFVRIRRQMPHLSDVIGTNFCDIGLAYNPVTNVLSVVSVIDNLMKGAAGQAVQ
NFNQLFGYDESLGLKFMPSL

Sequences:

>Translated_340_residues
MKKVAIVGIRGYSGLELFRIFYYHPEVEVTKIYATSHYGEKLSEHFPQLEGLTDLTISEFNEEEIMAECDAVFFATSAGV
SQKLALTFIDNNFPVIDLSGDFRLADLEIYNKWYKNTNLKNEYLLSGQYNLADIGQAKANYIANPGCYATATLLALYPLV
KNKMIDLDSIIVDAKSGLSGAGKGLSDASHFVNVVDNMSMYKINSHQHIPEIAQQLKIWNSNFQALQFSTSLIPVSRGIF
VSSYAKVAADFDFETIKNAYEQVYATKNFVRIRRQMPHLSDVIGTNFCDIGLAYNPVTNVLSVVSVIDNLMKGAAGQAVQ
NFNQLFGYDESLGLKFMPSL
>Mature_340_residues
MKKVAIVGIRGYSGLELFRIFYYHPEVEVTKIYATSHYGEKLSEHFPQLEGLTDLTISEFNEEEIMAECDAVFFATSAGV
SQKLALTFIDNNFPVIDLSGDFRLADLEIYNKWYKNTNLKNEYLLSGQYNLADIGQAKANYIANPGCYATATLLALYPLV
KNKMIDLDSIIVDAKSGLSGAGKGLSDASHFVNVVDNMSMYKINSHQHIPEIAQQLKIWNSNFQALQFSTSLIPVSRGIF
VSSYAKVAADFDFETIKNAYEQVYATKNFVRIRRQMPHLSDVIGTNFCDIGLAYNPVTNVLSVVSVIDNLMKGAAGQAVQ
NFNQLFGYDESLGLKFMPSL

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=343, Percent_Identity=35.8600583090379, Blast_Score=177, Evalue=9e-46,
Organism=Saccharomyces cerevisiae, GI6320913, Length=351, Percent_Identity=27.0655270655271, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_LACLA (Q9CHD5)

Other databases:

- EMBL:   AE005176
- PIR:   E86724
- RefSeq:   NP_266953.1
- ProteinModelPortal:   Q9CHD5
- SMR:   Q9CHD5
- GeneID:   1114424
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L0104
- NMPDR:   fig|272623.1.peg.817
- HOGENOM:   HBG294213
- OMA:   VCRIAVH
- ProtClustDB:   PRK00436
- BioCyc:   LLAC272623:L0104-MONOMER
- BRENDA:   1.2.1.38
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 37899; Mature: 37899

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 147-147

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVAIVGIRGYSGLELFRIFYYHPEVEVTKIYATSHYGEKLSEHFPQLEGLTDLTISEF
CCCEEEEEECCCCCCEEEEEEEECCCEEEEEEEEECHHHHHHHHHCHHHCCCCCCHHHHC
NEEEIMAECDAVFFATSAGVSQKLALTFIDNNFPVIDLSGDFRLADLEIYNKWYKNTNLK
CHHHHHHHHHHHEEEECCCCCCEEEEEEECCCCCEEEECCCEEEEHHHHHHHHHHCCCCC
NEYLLSGQYNLADIGQAKANYIANPGCYATATLLALYPLVKNKMIDLDSIIVDAKSGLSG
CEEEECCCCCHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHEEECCCCCCC
AGKGLSDASHFVNVVDNMSMYKINSHQHIPEIAQQLKIWNSNFQALQFSTSLIPVSRGIF
CCCCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCEEECCCCCH
VSSYAKVAADFDFETIKNAYEQVYATKNFVRIRRQMPHLSDVIGTNFCDIGLAYNPVTNV
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCHHHHH
LSVVSVIDNLMKGAAGQAVQNFNQLFGYDESLGLKFMPSL
HHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEECCCC
>Mature Secondary Structure
MKKVAIVGIRGYSGLELFRIFYYHPEVEVTKIYATSHYGEKLSEHFPQLEGLTDLTISEF
CCCEEEEEECCCCCCEEEEEEEECCCEEEEEEEEECHHHHHHHHHCHHHCCCCCCHHHHC
NEEEIMAECDAVFFATSAGVSQKLALTFIDNNFPVIDLSGDFRLADLEIYNKWYKNTNLK
CHHHHHHHHHHHEEEECCCCCCEEEEEEECCCCCEEEECCCEEEEHHHHHHHHHHCCCCC
NEYLLSGQYNLADIGQAKANYIANPGCYATATLLALYPLVKNKMIDLDSIIVDAKSGLSG
CEEEECCCCCHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHEEECCCCCCC
AGKGLSDASHFVNVVDNMSMYKINSHQHIPEIAQQLKIWNSNFQALQFSTSLIPVSRGIF
CCCCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCEEECCCCCH
VSSYAKVAADFDFETIKNAYEQVYATKNFVRIRRQMPHLSDVIGTNFCDIGLAYNPVTNV
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCHHHHH
LSVVSVIDNLMKGAAGQAVQNFNQLFGYDESLGLKFMPSL
HHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471