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The map label for this gene is argJ

Identifier: 15672780

GI number: 15672780

Start: 805075

End: 806265

Strand: Direct

Name: argJ

Synonym: L0105

Alternate gene names: 15672780

Gene position: 805075-806265 (Clockwise)

Preceding gene: 15672779

Following gene: 15672781

Centisome position: 34.03

GC content: 37.87

Gene sequence:

>1191_bases
ATGAAAGAAATAAAAGGGACAATTGCAAGTCCAAAGGGATTTTTGGCAGATGCTGTTCATGCACAATTAAAATATAAAAA
CTTAGATTTAGGGTTAATACTAAGTCAAGTTCCAGCTGCGATTGCTGGCGTTTTTACAACCAATAAAGTTTGTGCAGCGC
CAGTATTGATTGACCGTCAAATTGTCAAAAAAGGACAAGCACGGGCCATTATTTGTAATTCGGCGGTTGCCAATGCAGTA
ACAGGCGAGCAGGGTTATGCAAATGCTTTGAAAACACAAAAATTGCTTGCTGAAAAATTTGAACTCAAAGCTGAGGAAGT
GGCGGTTTGCTCAACAGGGGTCATTGGAGTACAGCTTCCGATGGAAAAAATTGCCACAGGAATTTCAAAGTTATCCCAAA
ATGAAGGGACAGCAGCATATTTTGCCAAAGCCATTTTAACAACAGATACCCAAACTAAAACAATTAACTTTGAAGCTGAA
ATTGGGGGTCAAATCGTGAATATGGCCGGGGTTTGTAAGGGATCGGGGATGATTCATCCAAATATGGCAACCATGCTTGC
TTTTATTACGACGGATGCAAAAATTGCTCAAGCTTTACTACAAAAAACATTATCAGAAATTATTGAAACGACATTTAATC
AGATTACAGTGGATGGAGATACTTCAACGAACGATACTGTTTTGTTGATGGCAAATGGCCAAGCTAAAAATAATGAAATT
TTAGAAGGAAGTTCAGACTATCTTTTGTTTAAAGAAATGCTGGCAAAGGTTTGTCAGTCCTTAGCCAAACAAATCGCCGC
TGATGGTGAAGGTGCAACTAAACTGATTGAAGTGACCGTCAAAGGAGCGCCAAATGATTTAACAGCGCGATTTATTGCCA
AAAAAATTGTGGGTTCAAGTTTAGTTAAAACGGCAATTTTTGGTGCAGACCCTAACTGGGGGCGGATTATTTCGTCAATT
GGTCAGGTGGCTAATTTTGAAGTTTCTGATATTGAATTAAAACTTCAAGATGAACTTGTGCTTTATCATTCAACACCAGT
TGACTTTGATGCAGCTTTTCTTTCTGAGAAATTAAAAGAAGATAAAATTGAAATTATTGCTGACTTGAATGCTGGAAGTG
GCTTGGGTCAGGCTTGGGGCTGTGATTTGACTTATAAATATGTCGAAATTAATGCTTTATATACAAGTTAA

Upstream 100 bases:

>100_bases
AAGGGGCTGCCGGACAAGCAGTACAAAATTTTAATCAGTTATTTGGCTACGATGAAAGTTTAGGCTTGAAATTTATGCCA
AGTCTTTAGAAGAGGAAGAA

Downstream 100 bases:

>100_bases
GAAGGAGAAAAAATGACAAATTTATTTGAAAATTATGGTCGCCTACCATTTAGCTTAATCAAAGGAGAAGATCAATATTT
ATTTGATGACAGGGGAAATA

Product: bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein

Products: NA

Alternate protein names: Glutamate N-acetyltransferase; Ornithine acetyltransferase; OATase; Ornithine transacetylase; Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MKEIKGTIASPKGFLADAVHAQLKYKNLDLGLILSQVPAAIAGVFTTNKVCAAPVLIDRQIVKKGQARAIICNSAVANAV
TGEQGYANALKTQKLLAEKFELKAEEVAVCSTGVIGVQLPMEKIATGISKLSQNEGTAAYFAKAILTTDTQTKTINFEAE
IGGQIVNMAGVCKGSGMIHPNMATMLAFITTDAKIAQALLQKTLSEIIETTFNQITVDGDTSTNDTVLLMANGQAKNNEI
LEGSSDYLLFKEMLAKVCQSLAKQIAADGEGATKLIEVTVKGAPNDLTARFIAKKIVGSSLVKTAIFGADPNWGRIISSI
GQVANFEVSDIELKLQDELVLYHSTPVDFDAAFLSEKLKEDKIEIIADLNAGSGLGQAWGCDLTYKYVEINALYTS

Sequences:

>Translated_396_residues
MKEIKGTIASPKGFLADAVHAQLKYKNLDLGLILSQVPAAIAGVFTTNKVCAAPVLIDRQIVKKGQARAIICNSAVANAV
TGEQGYANALKTQKLLAEKFELKAEEVAVCSTGVIGVQLPMEKIATGISKLSQNEGTAAYFAKAILTTDTQTKTINFEAE
IGGQIVNMAGVCKGSGMIHPNMATMLAFITTDAKIAQALLQKTLSEIIETTFNQITVDGDTSTNDTVLLMANGQAKNNEI
LEGSSDYLLFKEMLAKVCQSLAKQIAADGEGATKLIEVTVKGAPNDLTARFIAKKIVGSSLVKTAIFGADPNWGRIISSI
GQVANFEVSDIELKLQDELVLYHSTPVDFDAAFLSEKLKEDKIEIIADLNAGSGLGQAWGCDLTYKYVEINALYTS
>Mature_396_residues
MKEIKGTIASPKGFLADAVHAQLKYKNLDLGLILSQVPAAIAGVFTTNKVCAAPVLIDRQIVKKGQARAIICNSAVANAV
TGEQGYANALKTQKLLAEKFELKAEEVAVCSTGVIGVQLPMEKIATGISKLSQNEGTAAYFAKAILTTDTQTKTINFEAE
IGGQIVNMAGVCKGSGMIHPNMATMLAFITTDAKIAQALLQKTLSEIIETTFNQITVDGDTSTNDTVLLMANGQAKNNEI
LEGSSDYLLFKEMLAKVCQSLAKQIAADGEGATKLIEVTVKGAPNDLTARFIAKKIVGSSLVKTAIFGADPNWGRIISSI
GQVANFEVSDIELKLQDELVLYHSTPVDFDAAFLSEKLKEDKIEIIADLNAGSGLGQAWGCDLTYKYVEINALYTS

Specific function: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis:the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate

COG id: COG1364

COG function: function code E; N-acetylglutamate synthase (N-acetylornithine aminotransferase)

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgJ family

Homologues:

Organism=Saccharomyces cerevisiae, GI6323707, Length=414, Percent_Identity=38.8888888888889, Blast_Score=243, Evalue=4e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGJ_LACLA (Q9CHD4)

Other databases:

- EMBL:   AE005176
- PIR:   F86724
- RefSeq:   NP_266954.1
- ProteinModelPortal:   Q9CHD4
- SMR:   Q9CHD4
- MEROPS:   T05.001
- GeneID:   1114425
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L0105
- NMPDR:   fig|272623.1.peg.818
- HOGENOM:   HBG284202
- OMA:   QARAIIC
- ProtClustDB:   PRK05388
- BioCyc:   LLAC272623:L0105-MONOMER
- BRENDA:   2.3.1.1
- BRENDA:   2.3.1.35
- GO:   GO:0005737
- HAMAP:   MF_01106
- InterPro:   IPR002813
- InterPro:   IPR016117
- PANTHER:   PTHR23100
- TIGRFAMs:   TIGR00120

Pfam domain/function: PF01960 ArgJ; SSF56266 Pept_S58_DmpA/Arg_biosyn_ArgJ

EC number: =2.3.1.35; =2.3.1.1

Molecular weight: Translated: 42174; Mature: 42174

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEIKGTIASPKGFLADAVHAQLKYKNLDLGLILSQVPAAIAGVFTTNKVCAAPVLIDRQ
CCCCCCCCCCCCCHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHCCCHHHCHHHHHHH
IVKKGQARAIICNSAVANAVTGEQGYANALKTQKLLAEKFELKAEEVAVCSTGVIGVQLP
HHCCCCCCEEEECCHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHHEEEECCCEEEEECC
MEKIATGISKLSQNEGTAAYFAKAILTTDTQTKTINFEAEIGGQIVNMAGVCKGSGMIHP
HHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEEEEHHCCCEEEEHHHEECCCCEECC
NMATMLAFITTDAKIAQALLQKTLSEIIETTFNQITVDGDTSTNDTVLLMANGQAKNNEI
CHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCEEEEEECCCCCCCCC
LEGSSDYLLFKEMLAKVCQSLAKQIAADGEGATKLIEVTVKGAPNDLTARFIAKKIVGSS
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHH
LVKTAIFGADPNWGRIISSIGQVANFEVSDIELKLQDELVLYHSTPVDFDAAFLSEKLKE
HHHHHHCCCCCCHHHHHHHHHHHHCCEEEEEEEEEECCEEEEECCCCCHHHHHHHHHHCC
DKIEIIADLNAGSGLGQAWGCDLTYKYVEINALYTS
CCEEEEEECCCCCCCCCCCCCCEEEEEEEEEEEEEC
>Mature Secondary Structure
MKEIKGTIASPKGFLADAVHAQLKYKNLDLGLILSQVPAAIAGVFTTNKVCAAPVLIDRQ
CCCCCCCCCCCCCHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHCCCHHHCHHHHHHH
IVKKGQARAIICNSAVANAVTGEQGYANALKTQKLLAEKFELKAEEVAVCSTGVIGVQLP
HHCCCCCCEEEECCHHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHHEEEECCCEEEEECC
MEKIATGISKLSQNEGTAAYFAKAILTTDTQTKTINFEAEIGGQIVNMAGVCKGSGMIHP
HHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEEEEHHCCCEEEEHHHEECCCCEECC
NMATMLAFITTDAKIAQALLQKTLSEIIETTFNQITVDGDTSTNDTVLLMANGQAKNNEI
CHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCEEEEEECCCCCCCCC
LEGSSDYLLFKEMLAKVCQSLAKQIAADGEGATKLIEVTVKGAPNDLTARFIAKKIVGSS
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHH
LVKTAIFGADPNWGRIISSIGQVANFEVSDIELKLQDELVLYHSTPVDFDAAFLSEKLKE
HHHHHHCCCCCCHHHHHHHHHHHHCCEEEEEEEEEECCEEEEECCCCCHHHHHHHHHHCC
DKIEIIADLNAGSGLGQAWGCDLTYKYVEINALYTS
CCEEEEEECCCCCCCCCCCCCCEEEEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471