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The map label for this gene is engA

Identifier: 15672737

GI number: 15672737

Start: 761403

End: 762713

Strand: Direct

Name: engA

Synonym: L0156

Alternate gene names: 15672737

Gene position: 761403-762713 (Clockwise)

Preceding gene: 15672736

Following gene: 15672738

Centisome position: 32.19

GC content: 39.59

Gene sequence:

>1311_bases
ATGAGCTTACCTACAGTAGCCATCGTTGGCCGTCCAAATGTCGGAAAATCAACGATATTCAACCGTATTGCAGGAGAACG
CATCTCAATTGTCGAAGACATTCCAGGTGTAACTCGTGACCGTATCTATGCCACAGGAGAATGGTTAACCCGTAAATTCA
ATATCATCGATACAGGTGGGATTGAACTTTCAGACGAACCTTTCATGACTGAAATTCGAGCGCAAGCTGAAATTGCCATG
ACCGAAGCAGATGTTATCATCGCTGTTGTTGACGGAGAAACAGGTATTACAGATGCCGATGAAGCCGTTGCTAATATTCT
TTATCGTACAGATAAACCAGTTATTCTTGTTGTCAATAAAGTTGATAACCCAGAACGTCGAATGGAAATCTTTGATTTCT
ACTCACTTGGACTTGGCGATCCTTATCCTGTTTCAGCCGTTCACGGGATTGGGACAGGGGATGTCCTTGATGCAATCGTT
CAAAATCTTCCTAATGAAATTGAAGAAGAAAATGAGAATGTCATCAAGTTCAGCTTGATTGGCCGCCCAAACGTTGGGAA
ATCATCTCTTATTAATGCTATTCTTGGCGAAGACCGCGTAATTGCAAGTCCAATTGCAGGAACAACTCGTGATGCGATTG
ACACACACTTTGTCGATTCTGAAGACCAAGAATTTGTTATGATTGATACCGCCGGAATGCGTAAATCAGGAAAAATTTAC
GAAAATACTGAAAAATACTCAGTCATGCGTGCCATGCGTGCCATTGACCGTTCAGATATCGTTTTGATGGTGATTAACGC
TGAGGAAGGAATTCGCGAATATGATATGCGTATCGCTGGATTTGCTCACGAAGCTGGTAAAGGAATTTTGATTGTTGTCA
ATAAATGGGATACCCTTGAGAAAGATAACGATACAATGAAAAACTTTGAATTAGAAATTCGGACAAAGTTCAAATTCCTT
GATTATGCACCAATCGTTTATGTATCTGCTAAGACAGGACAACGTCTGAATAAACTCCCAGATATGATTAAAGAAATTCA
TCATGCACAAAACTTACGTATTTCAAGTTCTGTTTTGAATGATGTCATTATGGATGCTGTAGCGATTAATCCAACTCCGA
CGGACAAAGGAAAACGTTTGAAGATTTTCTATGCAACACAAGTAGCGATTAAACCACCAACTTTTGTTGTTTTTGTCAAT
GAAGAAGAACTCATGCACTTCTCATATCTTCGGTTCCTTGAAAATCAAATCCGTAAAGCCTTTGTTTTTGAAGGAACACC
AGTTCATTTGATTGCACGTAAACGTAAATAA

Upstream 100 bases:

>100_bases
CCTCGAAACCCAAATCTAAAATTATATAGTCTATGGATTACAAACTTCTTCACTATTATAATTTTTTATCCAATAAGTAA
ACAAAGAAAGAAATAAAAAT

Downstream 100 bases:

>100_bases
AAAAATTCACTGATTTTATCAGTGTTTTTTTATGCAAAATAATTGAAAAAATTTTAAATTTGAAATATACTATTAAAAAA
ATTAATTTAATTGAAAGAAG

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MSLPTVAIVGRPNVGKSTIFNRIAGERISIVEDIPGVTRDRIYATGEWLTRKFNIIDTGGIELSDEPFMTEIRAQAEIAM
TEADVIIAVVDGETGITDADEAVANILYRTDKPVILVVNKVDNPERRMEIFDFYSLGLGDPYPVSAVHGIGTGDVLDAIV
QNLPNEIEEENENVIKFSLIGRPNVGKSSLINAILGEDRVIASPIAGTTRDAIDTHFVDSEDQEFVMIDTAGMRKSGKIY
ENTEKYSVMRAMRAIDRSDIVLMVINAEEGIREYDMRIAGFAHEAGKGILIVVNKWDTLEKDNDTMKNFELEIRTKFKFL
DYAPIVYVSAKTGQRLNKLPDMIKEIHHAQNLRISSSVLNDVIMDAVAINPTPTDKGKRLKIFYATQVAIKPPTFVVFVN
EEELMHFSYLRFLENQIRKAFVFEGTPVHLIARKRK

Sequences:

>Translated_436_residues
MSLPTVAIVGRPNVGKSTIFNRIAGERISIVEDIPGVTRDRIYATGEWLTRKFNIIDTGGIELSDEPFMTEIRAQAEIAM
TEADVIIAVVDGETGITDADEAVANILYRTDKPVILVVNKVDNPERRMEIFDFYSLGLGDPYPVSAVHGIGTGDVLDAIV
QNLPNEIEEENENVIKFSLIGRPNVGKSSLINAILGEDRVIASPIAGTTRDAIDTHFVDSEDQEFVMIDTAGMRKSGKIY
ENTEKYSVMRAMRAIDRSDIVLMVINAEEGIREYDMRIAGFAHEAGKGILIVVNKWDTLEKDNDTMKNFELEIRTKFKFL
DYAPIVYVSAKTGQRLNKLPDMIKEIHHAQNLRISSSVLNDVIMDAVAINPTPTDKGKRLKIFYATQVAIKPPTFVVFVN
EEELMHFSYLRFLENQIRKAFVFEGTPVHLIARKRK
>Mature_435_residues
SLPTVAIVGRPNVGKSTIFNRIAGERISIVEDIPGVTRDRIYATGEWLTRKFNIIDTGGIELSDEPFMTEIRAQAEIAMT
EADVIIAVVDGETGITDADEAVANILYRTDKPVILVVNKVDNPERRMEIFDFYSLGLGDPYPVSAVHGIGTGDVLDAIVQ
NLPNEIEEENENVIKFSLIGRPNVGKSSLINAILGEDRVIASPIAGTTRDAIDTHFVDSEDQEFVMIDTAGMRKSGKIYE
NTEKYSVMRAMRAIDRSDIVLMVINAEEGIREYDMRIAGFAHEAGKGILIVVNKWDTLEKDNDTMKNFELEIRTKFKFLD
YAPIVYVSAKTGQRLNKLPDMIKEIHHAQNLRISSSVLNDVIMDAVAINPTPTDKGKRLKIFYATQVAIKPPTFVVFVNE
EELMHFSYLRFLENQIRKAFVFEGTPVHLIARKRK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=459, Percent_Identity=37.6906318082789, Blast_Score=309, Evalue=2e-85,
Organism=Escherichia coli, GI1788919, Length=176, Percent_Identity=31.8181818181818, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI2367268, Length=93, Percent_Identity=37.6344086021505, Blast_Score=65, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6323665, Length=173, Percent_Identity=34.6820809248555, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_LACLA (Q9CHH6)

Other databases:

- EMBL:   AE005176
- PIR:   C86719
- RefSeq:   NP_266911.1
- ProteinModelPortal:   Q9CHH6
- SMR:   Q9CHH6
- GeneID:   1114382
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L0156
- NMPDR:   fig|272623.1.peg.775
- HOGENOM:   HBG592135
- OMA:   TRDRTYQ
- ProtClustDB:   PRK00093
- BioCyc:   LLAC272623:L0156-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 48867; Mature: 48736

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLPTVAIVGRPNVGKSTIFNRIAGERISIVEDIPGVTRDRIYATGEWLTRKFNIIDTGG
CCCCEEEEEECCCCCHHHHHHHHCCCEEEHHHHCCCCCHHCEEECCHHHEEEEEEEECCC
IELSDEPFMTEIRAQAEIAMTEADVIIAVVDGETGITDADEAVANILYRTDKPVILVVNK
CEECCCCHHHHHHHHHEEEEEECCEEEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEEC
VDNPERRMEIFDFYSLGLGDPYPVSAVHGIGTGDVLDAIVQNLPNEIEEENENVIKFSLI
CCCHHHHHHHHHHHCCCCCCCCCCHHCCCCCCHHHHHHHHHHCCHHHHHCCCCEEEEEEE
GRPNVGKSSLINAILGEDRVIASPIAGTTRDAIDTHFVDSEDQEFVMIDTAGMRKSGKIY
CCCCCCHHHHHHHHHCCCCEEECCCCCCCHHHHHHCCCCCCCCCEEEEECCCCCCCCCEE
ENTEKYSVMRAMRAIDRSDIVLMVINAEEGIREYDMRIAGFAHEAGKGILIVVNKWDTLE
CCHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHEEEHHHCCCEEEEEEECCCCCC
KDNDTMKNFELEIRTKFKFLDYAPIVYVSAKTGQRLNKLPDMIKEIHHAQNLRISSSVLN
CCCCCHHCEEEEEEEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCEEHHHHHH
DVIMDAVAINPTPTDKGKRLKIFYATQVAIKPPTFVVFVNEEELMHFSYLRFLENQIRKA
HHHHHHEECCCCCCCCCCEEEEEEEEEEEECCCEEEEEECHHHHHHHHHHHHHHHHHHHE
FVFEGTPVHLIARKRK
EEECCCCEEEEEECCC
>Mature Secondary Structure 
SLPTVAIVGRPNVGKSTIFNRIAGERISIVEDIPGVTRDRIYATGEWLTRKFNIIDTGG
CCCEEEEEECCCCCHHHHHHHHCCCEEEHHHHCCCCCHHCEEECCHHHEEEEEEEECCC
IELSDEPFMTEIRAQAEIAMTEADVIIAVVDGETGITDADEAVANILYRTDKPVILVVNK
CEECCCCHHHHHHHHHEEEEEECCEEEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEEC
VDNPERRMEIFDFYSLGLGDPYPVSAVHGIGTGDVLDAIVQNLPNEIEEENENVIKFSLI
CCCHHHHHHHHHHHCCCCCCCCCCHHCCCCCCHHHHHHHHHHCCHHHHHCCCCEEEEEEE
GRPNVGKSSLINAILGEDRVIASPIAGTTRDAIDTHFVDSEDQEFVMIDTAGMRKSGKIY
CCCCCCHHHHHHHHHCCCCEEECCCCCCCHHHHHHCCCCCCCCCEEEEECCCCCCCCCEE
ENTEKYSVMRAMRAIDRSDIVLMVINAEEGIREYDMRIAGFAHEAGKGILIVVNKWDTLE
CCHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHEEEHHHCCCEEEEEEECCCCCC
KDNDTMKNFELEIRTKFKFLDYAPIVYVSAKTGQRLNKLPDMIKEIHHAQNLRISSSVLN
CCCCCHHCEEEEEEEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHCCEEHHHHHH
DVIMDAVAINPTPTDKGKRLKIFYATQVAIKPPTFVVFVNEEELMHFSYLRFLENQIRKA
HHHHHHEECCCCCCCCCCEEEEEEEEEEEECCCEEEEEECHHHHHHHHHHHHHHHHHHHE
FVFEGTPVHLIARKRK
EEECCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471