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The map label for this gene is codY

Identifier: 15672143

GI number: 15672143

Start: 164033

End: 164821

Strand: Direct

Name: codY

Synonym: L0243

Alternate gene names: 15672143

Gene position: 164033-164821 (Clockwise)

Preceding gene: 15672142

Following gene: 15672144

Centisome position: 6.93

GC content: 39.16

Gene sequence:

>789_bases
GTGGCTACATTACTTGAAAAAACACGTAAAATCACCGCGATTTTGCAAGATGGAGTGACCGATTTGCAACAAGAGTTGCC
ATATAACAGTATGACTGAACGCTTGGCAAACGTCATTGATTGCAATGCATGTGTGATTAATACGAAGGGCGAGTTGCTTG
GTTACTCATTGCCTTATAATACAAACAATGACCGTGTTGACCAATTTTTCTATGATCGTAAATTGCCTGATGAATATGTT
CGTGCGGCAGTACGTATCTACGATACAATGGCAAACGTTCCTGTTGACCGTCCATTAGCAATCTTCCCAGAAGAAAGCCT
TGGCGATTTTCCAAAAGGTGTGACAACTTTAGCACCTATTTATGGTTCTGGAATGCGTTTGGGAACATTTATCATGTGGC
GTGAAGACGGCGAATTCACTGATGATGATTTGGTCTTAGTTGAACTTGCAACAACAGTAATTGGTGTTCAACTCTCAAAT
CTTAAACTTGAACAAATGGAAGAAAATATCCGTAAAGACACCATGGCAACTATGGCTGTTAACACACTTTCATATTCAGA
AATGAAAGCTGTTAAAGCAATCATTGAAGAGCTTGATGGTGAAGAAGGGCATGTTATCGCTTCTGTCATTGCTGACAAGA
TTGGGATTACACGTTCAGTCATCGTTAACGCTTTGCGTAAACTCGAATCTGCTGGTGTAATTGAATCACGTTCACTTGGT
ATGAAAGGAACTTATCTTAAAGTTCTTAATACTGGTTTATTTGATAAACTTGCAGGACGTAATTTCTAA

Upstream 100 bases:

>100_bases
ATTTTCTGACAATTTTTATTGTTTTTCATGCTTTTTTATGTTATACTGATTATGAAAAATTTTGTATAAAAACAAGAATA
TAAAAAAATAGGAGAACAAA

Downstream 100 bases:

>100_bases
AAGCCAGGGTCTTAGCGCTTTAACGCTTAGACTTCGGCTTCACAAAAAGCTCCTATCGCAGATGGGAGCTTTTCGTGCTT
TATAAGAATTTCAAACAAAT

Product: transcriptional repressor CodY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MATLLEKTRKITAILQDGVTDLQQELPYNSMTERLANVIDCNACVINTKGELLGYSLPYNTNNDRVDQFFYDRKLPDEYV
RAAVRIYDTMANVPVDRPLAIFPEESLGDFPKGVTTLAPIYGSGMRLGTFIMWREDGEFTDDDLVLVELATTVIGVQLSN
LKLEQMEENIRKDTMATMAVNTLSYSEMKAVKAIIEELDGEEGHVIASVIADKIGITRSVIVNALRKLESAGVIESRSLG
MKGTYLKVLNTGLFDKLAGRNF

Sequences:

>Translated_262_residues
MATLLEKTRKITAILQDGVTDLQQELPYNSMTERLANVIDCNACVINTKGELLGYSLPYNTNNDRVDQFFYDRKLPDEYV
RAAVRIYDTMANVPVDRPLAIFPEESLGDFPKGVTTLAPIYGSGMRLGTFIMWREDGEFTDDDLVLVELATTVIGVQLSN
LKLEQMEENIRKDTMATMAVNTLSYSEMKAVKAIIEELDGEEGHVIASVIADKIGITRSVIVNALRKLESAGVIESRSLG
MKGTYLKVLNTGLFDKLAGRNF
>Mature_261_residues
ATLLEKTRKITAILQDGVTDLQQELPYNSMTERLANVIDCNACVINTKGELLGYSLPYNTNNDRVDQFFYDRKLPDEYVR
AAVRIYDTMANVPVDRPLAIFPEESLGDFPKGVTTLAPIYGSGMRLGTFIMWREDGEFTDDDLVLVELATTVIGVQLSNL
KLEQMEENIRKDTMATMAVNTLSYSEMKAVKAIIEELDGEEGHVIASVIADKIGITRSVIVNALRKLESAGVIESRSLGM
KGTYLKVLNTGLFDKLAGRNF

Specific function: DNA-binding protein that represses the expression of many genes essential for supplying Lactococcus lactis with amino acids during growth in milk. Seem to act on the major components of the proteolytic system, including the cell wall proteinase (PrtP), th

COG id: COG4465

COG function: function code K; Pleiotropic transcriptional repressor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CodY family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CODY_LACLA (Q9CJ45)

Other databases:

- EMBL:   AE005176
- PIR:   A86645
- RefSeq:   NP_266317.1
- ProteinModelPortal:   Q9CJ45
- GeneID:   1113769
- GenomeReviews:   AE005176_GR
- KEGG:   lla:L0243
- NMPDR:   fig|272623.1.peg.168
- HOGENOM:   HBG304760
- OMA:   HIFEELD
- ProtClustDB:   PRK04158
- BioCyc:   LLAC272623:L0243-MONOMER
- GO:   GO:0005737
- GO:   GO:0006350
- HAMAP:   MF_00621
- InterPro:   IPR014154
- InterPro:   IPR010312
- InterPro:   IPR013198
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PIRSF:   PIRSF011572
- TIGRFAMs:   TIGR02787

Pfam domain/function: PF06018 CodY; PF08222 HTH_CodY

EC number: NA

Molecular weight: Translated: 29129; Mature: 28998

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATLLEKTRKITAILQDGVTDLQQELPYNSMTERLANVIDCNACVINTKGELLGYSLPYN
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEECCCCEEEEECCCC
TNNDRVDQFFYDRKLPDEYVRAAVRIYDTMANVPVDRPLAIFPEESLGDFPKGVTTLAPI
CCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCHHCCCCCCCHHHHHHH
YGSGMRLGTFIMWREDGEFTDDDLVLVELATTVIGVQLSNLKLEQMEENIRKDTMATMAV
HCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
NTLSYSEMKAVKAIIEELDGEEGHVIASVIADKIGITRSVIVNALRKLESAGVIESRSLG
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCC
MKGTYLKVLNTGLFDKLAGRNF
CCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ATLLEKTRKITAILQDGVTDLQQELPYNSMTERLANVIDCNACVINTKGELLGYSLPYN
CHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEECCCCEEEEECCCC
TNNDRVDQFFYDRKLPDEYVRAAVRIYDTMANVPVDRPLAIFPEESLGDFPKGVTTLAPI
CCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCHHCCCCCCCHHHHHHH
YGSGMRLGTFIMWREDGEFTDDDLVLVELATTVIGVQLSNLKLEQMEENIRKDTMATMAV
HCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
NTLSYSEMKAVKAIIEELDGEEGHVIASVIADKIGITRSVIVNALRKLESAGVIESRSLG
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCC
MKGTYLKVLNTGLFDKLAGRNF
CCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471; 11401725