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The map label for this gene is aspC

Identifier: 15672142

GI number: 15672142

Start: 162666

End: 163880

Strand: Direct

Name: aspC

Synonym: L162604

Alternate gene names: 15672142

Gene position: 162666-163880 (Clockwise)

Preceding gene: 15672141

Following gene: 15672143

Centisome position: 6.88

GC content: 38.85

Gene sequence:

>1215_bases
ATGAGAAAATTTGAAAAATCGCATAAACTTGATAATGTCAGCTATGATATTCGTGGTCCAGTATTGGATGAAGCACAAAG
AATGCGAGCCAATGGTGAAAAAATTCTTCGATTGAATACAGGAAATCCAGCTGAATTTGGCTTTCTTGCTCCTGATGAAG
TCATTAGTGACTTGATTCAACATGCTGTGGATAGCGAAGGATATTCAGATTCTAAAGGGATTTTCTCGGCTCGTAAAGCG
ATTATGCAATACTGTCAGCTCAAGGGTTTTCCTAATCTTGATATCAATGATATTTTCACAGGTAATGGGGTTTCTGAATT
GATTGTTATGGCCATGCAGGGACTTTTGGACACAGGGGATGAGGTTTTGATTCCTATGCCTGATTATCCACTTTGGACGG
CTTCTGTCAGCTTAGCTGGAGGAACAGCTGTTCATTACCTCTGTGATGAACAGGCTGGTTGGTTCCCTGACATTGATGAT
ATTCGCTCAAAAATCACAAGTAATACAAAAGCCATTGTTTTGATTAATCCTAATAATCCAACGGGTGCGCTGTATTCTAA
AGATTTATTGCTTGAAATTGTTCAAGTGGCTAGAGAAAATAATTTAATTATTTTCTCTGACGAAATTTATGACCGATTGG
TTATGGATGGAGCAGTTCATGTTCCGATTGCTAGCTTGGCACCAGATCTTTTTGTGGTCACAATGAATGGCCTCTCAAAA
TCACACCGCATTGCGGGATTCCGTGTGGGGTGGATGGTTTTGTCAGGTGAAAAATCACATGTCAAGGGTTATATTGAAGG
TTTGAATATGCTGGCTTCAATGCGACTTTGTTCCAATGTTTTAGCTCAATCAGTCGTACAAACTTCACTTGGTGGCACTC
AATCGGTTGATAAATTGCTGTTGCCGGGTGGACGAGTTTATGAACAAAGAGAATTCATTTATAAAGCCATCAATGATATT
CCAGGATTATCTGCGGTCAAACCTCAAGCAGCTTTCTATATTTTCCCTAAAATTGACAGAGAAATGTATAAAATTGATAA
TGATGAACAATTTGTCTTGGACTTTTTGAAGCAGGAAAAAATCCTGCTTGTTCATGGTCGAGGATTTAATTGGAAAGAGC
CAGACCATTTCCGAATTGTTTATCTGCCTCGTGTGGACGAATTAGCGGAAATACAAGAAAAAATGGAACGTTTCCTTTGG
CAATATCGTAAATAA

Upstream 100 bases:

>100_bases
GAAAATATTTCCAAGTCTATAAAAAGAAATAAACTAGTGTTACCAGAATCTGTTTGTAAGTTTTGAAAATCAAAACTTCA
TAATATTACGGAGGTCAATA

Downstream 100 bases:

>100_bases
TAAATAGAAAAAGATGTATGAATAATTCGTATATCTTTTTTTGTTGAGAGTAATTTTCTGACAATTTTTATTGTTTTTCA
TGCTTTTTTATGTTATACTG

Product: aminotransferase AlaT

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MRKFEKSHKLDNVSYDIRGPVLDEAQRMRANGEKILRLNTGNPAEFGFLAPDEVISDLIQHAVDSEGYSDSKGIFSARKA
IMQYCQLKGFPNLDINDIFTGNGVSELIVMAMQGLLDTGDEVLIPMPDYPLWTASVSLAGGTAVHYLCDEQAGWFPDIDD
IRSKITSNTKAIVLINPNNPTGALYSKDLLLEIVQVARENNLIIFSDEIYDRLVMDGAVHVPIASLAPDLFVVTMNGLSK
SHRIAGFRVGWMVLSGEKSHVKGYIEGLNMLASMRLCSNVLAQSVVQTSLGGTQSVDKLLLPGGRVYEQREFIYKAINDI
PGLSAVKPQAAFYIFPKIDREMYKIDNDEQFVLDFLKQEKILLVHGRGFNWKEPDHFRIVYLPRVDELAEIQEKMERFLW
QYRK

Sequences:

>Translated_404_residues
MRKFEKSHKLDNVSYDIRGPVLDEAQRMRANGEKILRLNTGNPAEFGFLAPDEVISDLIQHAVDSEGYSDSKGIFSARKA
IMQYCQLKGFPNLDINDIFTGNGVSELIVMAMQGLLDTGDEVLIPMPDYPLWTASVSLAGGTAVHYLCDEQAGWFPDIDD
IRSKITSNTKAIVLINPNNPTGALYSKDLLLEIVQVARENNLIIFSDEIYDRLVMDGAVHVPIASLAPDLFVVTMNGLSK
SHRIAGFRVGWMVLSGEKSHVKGYIEGLNMLASMRLCSNVLAQSVVQTSLGGTQSVDKLLLPGGRVYEQREFIYKAINDI
PGLSAVKPQAAFYIFPKIDREMYKIDNDEQFVLDFLKQEKILLVHGRGFNWKEPDHFRIVYLPRVDELAEIQEKMERFLW
QYRK
>Mature_404_residues
MRKFEKSHKLDNVSYDIRGPVLDEAQRMRANGEKILRLNTGNPAEFGFLAPDEVISDLIQHAVDSEGYSDSKGIFSARKA
IMQYCQLKGFPNLDINDIFTGNGVSELIVMAMQGLLDTGDEVLIPMPDYPLWTASVSLAGGTAVHYLCDEQAGWFPDIDD
IRSKITSNTKAIVLINPNNPTGALYSKDLLLEIVQVARENNLIIFSDEIYDRLVMDGAVHVPIASLAPDLFVVTMNGLSK
SHRIAGFRVGWMVLSGEKSHVKGYIEGLNMLASMRLCSNVLAQSVVQTSLGGTQSVDKLLLPGGRVYEQREFIYKAINDI
PGLSAVKPQAAFYIFPKIDREMYKIDNDEQFVLDFLKQEKILLVHGRGFNWKEPDHFRIVYLPRVDELAEIQEKMERFLW
QYRK

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=391, Percent_Identity=26.5984654731458, Blast_Score=141, Evalue=9e-34,
Organism=Homo sapiens, GI215599424, Length=369, Percent_Identity=26.2872628726287, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI19263340, Length=369, Percent_Identity=26.2872628726287, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI4885351, Length=449, Percent_Identity=24.2761692650334, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI95147551, Length=432, Percent_Identity=22.2222222222222, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI169881279, Length=432, Percent_Identity=22.2222222222222, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI56713256, Length=367, Percent_Identity=23.9782016348774, Blast_Score=89, Evalue=9e-18,
Organism=Homo sapiens, GI56713254, Length=367, Percent_Identity=23.9782016348774, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI149944424, Length=358, Percent_Identity=24.3016759776536, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI169881281, Length=342, Percent_Identity=21.0526315789474, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1788627, Length=404, Percent_Identity=62.1287128712871, Blast_Score=543, Evalue=1e-156,
Organism=Escherichia coli, GI1788722, Length=403, Percent_Identity=24.5657568238213, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1786816, Length=264, Percent_Identity=23.8636363636364, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787909, Length=302, Percent_Identity=21.8543046357616, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17567663, Length=380, Percent_Identity=27.1052631578947, Blast_Score=164, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI71981209, Length=473, Percent_Identity=24.7357293868922, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71994472, Length=167, Percent_Identity=32.3353293413174, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI71994476, Length=167, Percent_Identity=32.3353293413174, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17567369, Length=220, Percent_Identity=28.1818181818182, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71981215, Length=306, Percent_Identity=24.1830065359477, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6323118, Length=472, Percent_Identity=25.4237288135593, Blast_Score=124, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6320317, Length=382, Percent_Identity=26.1780104712042, Blast_Score=120, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6322401, Length=349, Percent_Identity=24.0687679083095, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI18859735, Length=371, Percent_Identity=28.8409703504043, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI45551451, Length=499, Percent_Identity=25.6513026052104, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24641770, Length=499, Percent_Identity=25.6513026052104, Blast_Score=125, Evalue=7e-29,
Organism=Drosophila melanogaster, GI24641760, Length=499, Percent_Identity=25.6513026052104, Blast_Score=125, Evalue=7e-29,
Organism=Drosophila melanogaster, GI24641768, Length=499, Percent_Identity=25.6513026052104, Blast_Score=125, Evalue=7e-29,
Organism=Drosophila melanogaster, GI24641766, Length=499, Percent_Identity=25.6513026052104, Blast_Score=125, Evalue=7e-29,
Organism=Drosophila melanogaster, GI24641764, Length=499, Percent_Identity=25.6513026052104, Blast_Score=125, Evalue=7e-29,
Organism=Drosophila melanogaster, GI28573069, Length=270, Percent_Identity=27.037037037037, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24646114, Length=270, Percent_Identity=27.037037037037, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI28573067, Length=270, Percent_Identity=27.037037037037, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI28573065, Length=270, Percent_Identity=27.037037037037, Blast_Score=96, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 45496; Mature: 45496

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKFEKSHKLDNVSYDIRGPVLDEAQRMRANGEKILRLNTGNPAEFGFLAPDEVISDLIQ
CCCCCCCCCCCCCCEECCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
HAVDSEGYSDSKGIFSARKAIMQYCQLKGFPNLDINDIFTGNGVSELIVMAMQGLLDTGD
HHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCHHHHHHHHHHHHHCCCC
EVLIPMPDYPLWTASVSLAGGTAVHYLCDEQAGWFPDIDDIRSKITSNTKAIVLINPNNP
CEEEECCCCCCEEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCEEEEECCCCC
TGALYSKDLLLEIVQVARENNLIIFSDEIYDRLVMDGAVHVPIASLAPDLFVVTMNGLSK
CCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCCCCHHHHCCCEEEEEECCCCC
SHRIAGFRVGWMVLSGEKSHVKGYIEGLNMLASMRLCSNVLAQSVVQTSLGGTQSVDKLL
CCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LPGGRVYEQREFIYKAINDIPGLSAVKPQAAFYIFPKIDREMYKIDNDEQFVLDFLKQEK
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCHHHHCCCCHHHHHHHHCCCC
ILLVHGRGFNWKEPDHFRIVYLPRVDELAEIQEKMERFLWQYRK
EEEEECCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRKFEKSHKLDNVSYDIRGPVLDEAQRMRANGEKILRLNTGNPAEFGFLAPDEVISDLIQ
CCCCCCCCCCCCCCEECCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
HAVDSEGYSDSKGIFSARKAIMQYCQLKGFPNLDINDIFTGNGVSELIVMAMQGLLDTGD
HHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCHHHHHHHHHHHHHCCCC
EVLIPMPDYPLWTASVSLAGGTAVHYLCDEQAGWFPDIDDIRSKITSNTKAIVLINPNNP
CEEEECCCCCCEEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCEEEEECCCCC
TGALYSKDLLLEIVQVARENNLIIFSDEIYDRLVMDGAVHVPIASLAPDLFVVTMNGLSK
CCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCCCCCCHHHHCCCEEEEEECCCCC
SHRIAGFRVGWMVLSGEKSHVKGYIEGLNMLASMRLCSNVLAQSVVQTSLGGTQSVDKLL
CCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LPGGRVYEQREFIYKAINDIPGLSAVKPQAAFYIFPKIDREMYKIDNDEQFVLDFLKQEK
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCHHHHCCCCHHHHHHHHCCCC
ILLVHGRGFNWKEPDHFRIVYLPRVDELAEIQEKMERFLWQYRK
EEEEECCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]