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The map label for this gene is secA

Identifier: 15672097

GI number: 15672097

Start: 116366

End: 118963

Strand: Direct

Name: secA

Synonym: L0334

Alternate gene names: 15672097

Gene position: 116366-118963 (Clockwise)

Preceding gene: 15672094

Following gene: 15672098

Centisome position: 4.92

GC content: 38.68

Gene sequence:

>2598_bases
ATGCCGAATATTATTAGAAAACTTGTCGAAAACGACAAAAAAGAGCTCAAAAAACTCAATAGAATGGCGCTTCAAGTTGA
AAGTTTCGCTGATGAAATGGAACATTTGACTGATGAGCAATTGAAAGCCAAAACACCCGAATTAAAAGAACGTATTGCAA
AAGGAGAAAGTCTTGATGATCTTCTCTATGAAGCATTTGCTGTCTGTCGTGAAGCAGCCCGCCGTGTGCTTGGCTTATAC
CCTTTCCACGTTCAAATTATGGGTGGGATTGTCTTACATAATGGTGACGTTCCCGAAATGCGTACTGGTGAAGGTAAAAC
TTTAACTGCGACAATGCCAGTTTATCTTAACGCTTTGTCAGGTAAAGGCGTTCACGTTGTTACTGTCAATGAATATTTGG
CAACACGTGATATGACTGAAATGGGTGAACTTTACAGCTGGCTTGGATTGACTGTTGGTTTGAACTTGAATTCAAAATCA
CCAGAAGAAAAACGTGAAGCTTACAACTGTGACATCACTTATTCAACATCAGCTGAGCTTGGCTTTGATTATCTTCGTGA
TAACATGGTGACACGTGCCGAAGATATGGTTCAAAAGCCATTGAACTATGCTCTTGTCGATGAAGTTGACTCAATCTTGG
TCGATGAAGCCAGAACACCTTTGATTATTTCTGGACAAGCTGAAAGTTCATCAGCACTTTACTATCGTGCTGACCAATTT
ACTAAGACATTAAAAGGTCAAAACTTGAATGTTGCTACTTCTGAATATGAAGAAGGCGACGATTATAAGATTGATTTACA
ATCAAAAACAATTTCCTTAACTGAAGAAGGAATTGATAAGGCCGAAAAATTCTTCCAAATCGAAAATCTTTATGATATGG
AAAATGTTGCCTTAACTCACTTTGTAGATAATGCTTTACGTGCCAACTTTATCATGCTTCACGACATCGACTATATGGTT
GATGAAAACCAAGAAGTTTTGATTATTGACCAATTTACTGGACGTACGATGCCTGGACGTCGCTATTCTGATGGTCTTCA
CCAAGCAATTGAAGCTAAAGAAGCTGTGCCAATTCAAGATGAATCAAAAACAATGGCTTCAATTACGATTCAAAACTACT
TCCGGATGTATAAAAAACTGTCAGGGATGACAGGGACTGCTAAAACCGAAGAAGAAGAATTCCGTGAGATTTATAACATT
CAAATCACACCAATTCCAACCAACCGTCCTGTTCAACGTTTAGATCATCCAGATTTACTTTACCCAACTTTGGAAGCTAA
ATTTAAAGCAGTTATTGATGATATTAAACGTCGTCATGCTGAAGGTCAACCAATATTGATTGGTACTGTTGCTGTCGAAA
CTTCCGAATTGATTTCTAAGAAATTGGTTGAAGCAAAAATTCCTCACGAAGTTTTGAATGCGAAAAATCACTTCCGTGAA
GCACAAATCATCATGAATGCGGGTCAACAAGGAGCAGTAACGATTGCGACCAACATGGCCGGTCGTGGGACTGATATCAA
GCTTGGGCCTGGTGTAATTGATCATGTAGACCCTGAATTCCGAGGTCTTGCTGTTATTGGTACTGAGCGTCATGAATCTC
GTCGTATTGATAATCAATTACGTGGTCGTTCTGGACGTCAAGGTGACCCAGGGGTTTCACAATTCTATCTTTCTCTTGAA
GATGAATTAATGAAACGTTTTGGTTCGGAACGTGTTTCAGCTTTCCTAGATAGAATGCGTATTTCTGGTGAAGATGCTGT
CATCAAATCTGGCTTGATTACTCGTCAGATTGAAAGTTCACAAAAACGTGTCGAAGGAAATAACTACGATTCTCGTAAAC
AAGTCTTGCAATATGATGATGTCATCCGTGAGCAACGTGAAGTTATTTATGCGCAACGTCAGGAAGTTATCTTGGCTACA
GAAGATATGACTCCTGTTTTGATGGGCATGTTCAAGCGAACAATTGATCGTCAAGTGGATGGTCATGAACTTGCAGGAAG
TCTTAAAGATGAAGAAAATGTCAAAAATCTCTTGCAAACATTACACAATACAATGTTGCCAGAAGATGGCATTGAATTGT
CTGAACTGACAGGTTTGTCAGTACAAGCAATGAAAGATTTGATTTTTGATAAAGTCAAAGCTCGTTATGCTTCACAAATG
GAAAAATTATCTGACCCAGAACGTCAGTTGGAATTCCAACGTGCAGTTATCTTACGAGTTGTTGATAATAACTGGTCAGA
ACACATTGATGCGCTTGACCAAATGCGTCAATCAGTAGGACTTCGTGGTTATGCCCAAAATAACCCTATTGTTGAATATC
AAGAAGAATCATATAAAATGTACAATAATATGATTGGTGCGATTGAATTTGAAGTGACTCGTTTGATGATGAAAGCTCAA
ATTCAACCACAAACGGCAATCCGTCAGGAAGCGCCAAGAATGACAACCACAGCTTCACAAGAAAATATTACAAATGTTGA
TACTGAACATTCTGTCAGTGAAGAAATTTCATTTGAAAATGTTGGTCGTAACGACCTTTGTCCTTGTGGTTCTGGTAAGA
AGTTTAAAAATTGTCACGGACGTACACATATTGCCTAA

Upstream 100 bases:

>100_bases
GAATTAAATTCGAATTATTTGTGGTATTTCAGTTTGTAAAAGCTATGTAAAAGTGTTACAATTAATGGTAATATCCACTT
ATTTTTGTGAAAGAGAAATT

Downstream 100 bases:

>100_bases
AATGCCAATTAATTTACTGACAGTTCTGTCAGTAAATTTTTTTATATTAATGGACGCAAATAAGTATAGAATTAAATAAA
TTTTTGATACAATAGATAAA

Product: preprotein translocase subunit SecA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 865; Mature: 864

Protein sequence:

>865_residues
MPNIIRKLVENDKKELKKLNRMALQVESFADEMEHLTDEQLKAKTPELKERIAKGESLDDLLYEAFAVCREAARRVLGLY
PFHVQIMGGIVLHNGDVPEMRTGEGKTLTATMPVYLNALSGKGVHVVTVNEYLATRDMTEMGELYSWLGLTVGLNLNSKS
PEEKREAYNCDITYSTSAELGFDYLRDNMVTRAEDMVQKPLNYALVDEVDSILVDEARTPLIISGQAESSSALYYRADQF
TKTLKGQNLNVATSEYEEGDDYKIDLQSKTISLTEEGIDKAEKFFQIENLYDMENVALTHFVDNALRANFIMLHDIDYMV
DENQEVLIIDQFTGRTMPGRRYSDGLHQAIEAKEAVPIQDESKTMASITIQNYFRMYKKLSGMTGTAKTEEEEFREIYNI
QITPIPTNRPVQRLDHPDLLYPTLEAKFKAVIDDIKRRHAEGQPILIGTVAVETSELISKKLVEAKIPHEVLNAKNHFRE
AQIIMNAGQQGAVTIATNMAGRGTDIKLGPGVIDHVDPEFRGLAVIGTERHESRRIDNQLRGRSGRQGDPGVSQFYLSLE
DELMKRFGSERVSAFLDRMRISGEDAVIKSGLITRQIESSQKRVEGNNYDSRKQVLQYDDVIREQREVIYAQRQEVILAT
EDMTPVLMGMFKRTIDRQVDGHELAGSLKDEENVKNLLQTLHNTMLPEDGIELSELTGLSVQAMKDLIFDKVKARYASQM
EKLSDPERQLEFQRAVILRVVDNNWSEHIDALDQMRQSVGLRGYAQNNPIVEYQEESYKMYNNMIGAIEFEVTRLMMKAQ
IQPQTAIRQEAPRMTTTASQENITNVDTEHSVSEEISFENVGRNDLCPCGSGKKFKNCHGRTHIA

Sequences:

>Translated_865_residues
MPNIIRKLVENDKKELKKLNRMALQVESFADEMEHLTDEQLKAKTPELKERIAKGESLDDLLYEAFAVCREAARRVLGLY
PFHVQIMGGIVLHNGDVPEMRTGEGKTLTATMPVYLNALSGKGVHVVTVNEYLATRDMTEMGELYSWLGLTVGLNLNSKS
PEEKREAYNCDITYSTSAELGFDYLRDNMVTRAEDMVQKPLNYALVDEVDSILVDEARTPLIISGQAESSSALYYRADQF
TKTLKGQNLNVATSEYEEGDDYKIDLQSKTISLTEEGIDKAEKFFQIENLYDMENVALTHFVDNALRANFIMLHDIDYMV
DENQEVLIIDQFTGRTMPGRRYSDGLHQAIEAKEAVPIQDESKTMASITIQNYFRMYKKLSGMTGTAKTEEEEFREIYNI
QITPIPTNRPVQRLDHPDLLYPTLEAKFKAVIDDIKRRHAEGQPILIGTVAVETSELISKKLVEAKIPHEVLNAKNHFRE
AQIIMNAGQQGAVTIATNMAGRGTDIKLGPGVIDHVDPEFRGLAVIGTERHESRRIDNQLRGRSGRQGDPGVSQFYLSLE
DELMKRFGSERVSAFLDRMRISGEDAVIKSGLITRQIESSQKRVEGNNYDSRKQVLQYDDVIREQREVIYAQRQEVILAT
EDMTPVLMGMFKRTIDRQVDGHELAGSLKDEENVKNLLQTLHNTMLPEDGIELSELTGLSVQAMKDLIFDKVKARYASQM
EKLSDPERQLEFQRAVILRVVDNNWSEHIDALDQMRQSVGLRGYAQNNPIVEYQEESYKMYNNMIGAIEFEVTRLMMKAQ
IQPQTAIRQEAPRMTTTASQENITNVDTEHSVSEEISFENVGRNDLCPCGSGKKFKNCHGRTHIA
>Mature_864_residues
PNIIRKLVENDKKELKKLNRMALQVESFADEMEHLTDEQLKAKTPELKERIAKGESLDDLLYEAFAVCREAARRVLGLYP
FHVQIMGGIVLHNGDVPEMRTGEGKTLTATMPVYLNALSGKGVHVVTVNEYLATRDMTEMGELYSWLGLTVGLNLNSKSP
EEKREAYNCDITYSTSAELGFDYLRDNMVTRAEDMVQKPLNYALVDEVDSILVDEARTPLIISGQAESSSALYYRADQFT
KTLKGQNLNVATSEYEEGDDYKIDLQSKTISLTEEGIDKAEKFFQIENLYDMENVALTHFVDNALRANFIMLHDIDYMVD
ENQEVLIIDQFTGRTMPGRRYSDGLHQAIEAKEAVPIQDESKTMASITIQNYFRMYKKLSGMTGTAKTEEEEFREIYNIQ
ITPIPTNRPVQRLDHPDLLYPTLEAKFKAVIDDIKRRHAEGQPILIGTVAVETSELISKKLVEAKIPHEVLNAKNHFREA
QIIMNAGQQGAVTIATNMAGRGTDIKLGPGVIDHVDPEFRGLAVIGTERHESRRIDNQLRGRSGRQGDPGVSQFYLSLED
ELMKRFGSERVSAFLDRMRISGEDAVIKSGLITRQIESSQKRVEGNNYDSRKQVLQYDDVIREQREVIYAQRQEVILATE
DMTPVLMGMFKRTIDRQVDGHELAGSLKDEENVKNLLQTLHNTMLPEDGIELSELTGLSVQAMKDLIFDKVKARYASQME
KLSDPERQLEFQRAVILRVVDNNWSEHIDALDQMRQSVGLRGYAQNNPIVEYQEESYKMYNNMIGAIEFEVTRLMMKAQI
QPQTAIRQEAPRMTTTASQENITNVDTEHSVSEEISFENVGRNDLCPCGSGKKFKNCHGRTHIA

Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular mo

COG id: COG0653

COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secA family

Homologues:

Organism=Escherichia coli, GI1786287, Length=898, Percent_Identity=45.6570155902004, Blast_Score=743, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SECA_LACLA (Q9CJ85)

Other databases:

- EMBL:   AE005176
- PIR:   C86639
- RefSeq:   NP_266271.1
- HSSP:   P10408
- ProteinModelPortal:   Q9CJ85
- SMR:   Q9CJ85
- GeneID:   1113721
- GenomeReviews:   AE005176_GR
- NMPDR:   fig|272623.1.peg.122
- HOGENOM:   HBG284200
- OMA:   GGMVLHD
- ProtClustDB:   PRK12904
- BioCyc:   LLAC272623:L0334-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01382
- InterPro:   IPR004027
- InterPro:   IPR000185
- InterPro:   IPR020937
- InterPro:   IPR011115
- InterPro:   IPR014018
- InterPro:   IPR011130
- InterPro:   IPR011116
- Gene3D:   G3DSA:1.10.3060.10
- PRINTS:   PR00906
- SMART:   SM00957
- SMART:   SM00958
- TIGRFAMs:   TIGR00963

Pfam domain/function: PF02810 SEC-C; PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW; SSF81767 SecA_PP_bd; SSF81886 SecA_SW

EC number: NA

Molecular weight: Translated: 98171; Mature: 98039

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS01312 SECA; PS51196 SECA_MOTOR_DEAD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNIIRKLVENDKKELKKLNRMALQVESFADEMEHLTDEQLKAKTPELKERIAKGESLDD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHH
LLYEAFAVCREAARRVLGLYPFHVQIMGGIVLHNGDVPEMRTGEGKTLTATMPVYLNALS
HHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEECCCCCCCCCCCCCEEEEECCCCEECCC
GKGVHVVTVNEYLATRDMTEMGELYSWLGLTVGLNLNSKSPEEKREAYNCDITYSTSAEL
CCCEEEEEEHHHHHHCCHHHHHHHHHHHHHEEEECCCCCCCHHHHHHCCCCEEECCCHHH
GFDYLRDNMVTRAEDMVQKPLNYALVDEVDSILVDEARTPLIISGQAESSSALYYRADQF
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEHHHH
TKTLKGQNLNVATSEYEEGDDYKIDLQSKTISLTEEGIDKAEKFFQIENLYDMENVALTH
HHHHCCCCCCEEECCCCCCCCEEEEECCCEEEHHHHHHHHHHHHHHHHHHHCHHHHHHHH
FVDNALRANFIMLHDIDYMVDENQEVLIIDQFTGRTMPGRRYSDGLHQAIEAKEAVPIQD
HHHHHHHCCEEEEEECHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCC
ESKTMASITIQNYFRMYKKLSGMTGTAKTEEEEFREIYNIQITPIPTNRPVQRLDHPDLL
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCEEEECCCCCCHHHCCCCCCC
YPTLEAKFKAVIDDIKRRHAEGQPILIGTVAVETSELISKKLVEAKIPHEVLNAKNHFRE
CHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHH
AQIIMNAGQQGAVTIATNMAGRGTDIKLGPGVIDHVDPEFRGLAVIGTERHESRRIDNQL
HHHHHCCCCCCCEEEEECCCCCCCCEEECCCCCCCCCCCCCCEEEEECCCHHHHHHHHHH
RGRSGRQGDPGVSQFYLSLEDELMKRFGSERVSAFLDRMRISGEDAVIKSGLITRQIESS
CCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHH
QKRVEGNNYDSRKQVLQYDDVIREQREVIYAQRQEVILATEDMTPVLMGMFKRTIDRQVD
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCC
GHELAGSLKDEENVKNLLQTLHNTMLPEDGIELSELTGLSVQAMKDLIFDKVKARYASQM
CHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHH
EKLSDPERQLEFQRAVILRVVDNNWSEHIDALDQMRQSVGLRGYAQNNPIVEYQEESYKM
HHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEECHHHHHH
YNNMIGAIEFEVTRLMMKAQIQPQTAIRQEAPRMTTTASQENITNVDTEHSVSEEISFEN
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHCCHHC
VGRNDLCPCGSGKKFKNCHGRTHIA
CCCCCCCCCCCCCCHHCCCCCCCCC
>Mature Secondary Structure 
PNIIRKLVENDKKELKKLNRMALQVESFADEMEHLTDEQLKAKTPELKERIAKGESLDD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHH
LLYEAFAVCREAARRVLGLYPFHVQIMGGIVLHNGDVPEMRTGEGKTLTATMPVYLNALS
HHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEECCCCCCCCCCCCCEEEEECCCCEECCC
GKGVHVVTVNEYLATRDMTEMGELYSWLGLTVGLNLNSKSPEEKREAYNCDITYSTSAEL
CCCEEEEEEHHHHHHCCHHHHHHHHHHHHHEEEECCCCCCCHHHHHHCCCCEEECCCHHH
GFDYLRDNMVTRAEDMVQKPLNYALVDEVDSILVDEARTPLIISGQAESSSALYYRADQF
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEEEHHHH
TKTLKGQNLNVATSEYEEGDDYKIDLQSKTISLTEEGIDKAEKFFQIENLYDMENVALTH
HHHHCCCCCCEEECCCCCCCCEEEEECCCEEEHHHHHHHHHHHHHHHHHHHCHHHHHHHH
FVDNALRANFIMLHDIDYMVDENQEVLIIDQFTGRTMPGRRYSDGLHQAIEAKEAVPIQD
HHHHHHHCCEEEEEECHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCC
ESKTMASITIQNYFRMYKKLSGMTGTAKTEEEEFREIYNIQITPIPTNRPVQRLDHPDLL
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCEEEECCCCCCHHHCCCCCCC
YPTLEAKFKAVIDDIKRRHAEGQPILIGTVAVETSELISKKLVEAKIPHEVLNAKNHFRE
CHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHH
AQIIMNAGQQGAVTIATNMAGRGTDIKLGPGVIDHVDPEFRGLAVIGTERHESRRIDNQL
HHHHHCCCCCCCEEEEECCCCCCCCEEECCCCCCCCCCCCCCEEEEECCCHHHHHHHHHH
RGRSGRQGDPGVSQFYLSLEDELMKRFGSERVSAFLDRMRISGEDAVIKSGLITRQIESS
CCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHH
QKRVEGNNYDSRKQVLQYDDVIREQREVIYAQRQEVILATEDMTPVLMGMFKRTIDRQVD
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCC
GHELAGSLKDEENVKNLLQTLHNTMLPEDGIELSELTGLSVQAMKDLIFDKVKARYASQM
CHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHH
EKLSDPERQLEFQRAVILRVVDNNWSEHIDALDQMRQSVGLRGYAQNNPIVEYQEESYKM
HHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEECHHHHHH
YNNMIGAIEFEVTRLMMKAQIQPQTAIRQEAPRMTTTASQENITNVDTEHSVSEEISFEN
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHCCHHC
VGRNDLCPCGSGKKFKNCHGRTHIA
CCCCCCCCCCCCCCHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11337471