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The map label for this gene is aroF

Identifier: 15672098

GI number: 15672098

Start: 119092

End: 120129

Strand: Direct

Name: aroF

Synonym: L0063

Alternate gene names: 15672098

Gene position: 119092-120129 (Clockwise)

Preceding gene: 15672097

Following gene: 15672099

Centisome position: 5.03

GC content: 36.03

Gene sequence:

>1038_bases
ATGAGTTTTAAAGAAATAAGTCCTAAGATAAATATTGATGCAATTAAGATGTTGGGACATCTCAACAGTGAGCAACAAGA
AAAAAAATTGCAACGAGATAAAGAACTTGAAGCAATTATAAAAGGTGAAGATGACCGTTTACTCTTGATTATTGGGCCAT
GTTCGTCAGACAATGAAGAAGCAGTTTTAGAATATGCTCGCCGTTTAGCTAAACTTCAAGAAGCAGTTAAAGATAAAATT
TTTATGGTCATGCGTGTCTATACTGCAAAACCTCGTACAAATGGCGATGGCTATAAAGGATTGATTCACGAACCAGATGC
TGATGGTCATACCGATTTAATCAATGGAATCAAAATGGTTCGTGACTTACATTACAAGGTCATCACTGAAACTGGTTTAA
CAACTGCTGATGAAATGCTTTACCCAGAAAATCTTCCAATGGTAGATGATTTGGTCAGCTACCATGCGATTGGTGCACGT
TCTGTTGAAAATCAACAACACCGTTTTGTTGCTTCTGGGATTGATGTGCCAACTGGTTTGAAAAATCCAACATCAGGAAA
TTTGAAAGTGATGTTTAATGGAATTTACGCGGCTCAACAATCACAAGATTTCCTCTTTGGTCGTGCAGAAGTTCAAACAT
CAGGAAATCCTTTAGCACATGCGATTTTGCGTGGTGGACAAGATGAAAATGGAAAATACCATCCAAACTACTACACTGAT
AACTTGCTTGATACAATTGAAATTTATGAAAAAATGGGCTTGAAAAATCCTTTTATTGTCATTGATACAAACCATGATAA
CTCTGGTAAGAAATTTATGGAACAAATCCGTATTGTTCGTCAAACCTTAGTTAATCGTGACTGGGATGATAAAATTCGCC
AAAATGTTCGTGGCTTCATGATTGAATCTTACCTAGAAGATGGTCGCCAAGATAAACCAGAAGTATTTGGTAAATCAATT
ACTGACCCATGTTTAGGTTGGGATAAAACAGAAGCACTTGTTCAAGAAATTTACGAAGCTGAAAACAAAAATAACTAA

Upstream 100 bases:

>100_bases
TCAGTAAATTTTTTTATATTAATGGACGCAAATAAGTATAGAATTAAATAAATTTTTGATACAATAGATAAAATAACAAA
GCGAAATACGAGGAATTGGA

Downstream 100 bases:

>100_bases
AAATGAAAGCTGTCAGAACTGACAGCTTTTTTTCAGCTCATTTTCTTCAGGAAAATAATATAAAAAATACTTATTTGATG
ATAAAAGAAATCAAAGTCTA

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MSFKEISPKINIDAIKMLGHLNSEQQEKKLQRDKELEAIIKGEDDRLLLIIGPCSSDNEEAVLEYARRLAKLQEAVKDKI
FMVMRVYTAKPRTNGDGYKGLIHEPDADGHTDLINGIKMVRDLHYKVITETGLTTADEMLYPENLPMVDDLVSYHAIGAR
SVENQQHRFVASGIDVPTGLKNPTSGNLKVMFNGIYAAQQSQDFLFGRAEVQTSGNPLAHAILRGGQDENGKYHPNYYTD
NLLDTIEIYEKMGLKNPFIVIDTNHDNSGKKFMEQIRIVRQTLVNRDWDDKIRQNVRGFMIESYLEDGRQDKPEVFGKSI
TDPCLGWDKTEALVQEIYEAENKNN

Sequences:

>Translated_345_residues
MSFKEISPKINIDAIKMLGHLNSEQQEKKLQRDKELEAIIKGEDDRLLLIIGPCSSDNEEAVLEYARRLAKLQEAVKDKI
FMVMRVYTAKPRTNGDGYKGLIHEPDADGHTDLINGIKMVRDLHYKVITETGLTTADEMLYPENLPMVDDLVSYHAIGAR
SVENQQHRFVASGIDVPTGLKNPTSGNLKVMFNGIYAAQQSQDFLFGRAEVQTSGNPLAHAILRGGQDENGKYHPNYYTD
NLLDTIEIYEKMGLKNPFIVIDTNHDNSGKKFMEQIRIVRQTLVNRDWDDKIRQNVRGFMIESYLEDGRQDKPEVFGKSI
TDPCLGWDKTEALVQEIYEAENKNN
>Mature_344_residues
SFKEISPKINIDAIKMLGHLNSEQQEKKLQRDKELEAIIKGEDDRLLLIIGPCSSDNEEAVLEYARRLAKLQEAVKDKIF
MVMRVYTAKPRTNGDGYKGLIHEPDADGHTDLINGIKMVRDLHYKVITETGLTTADEMLYPENLPMVDDLVSYHAIGARS
VENQQHRFVASGIDVPTGLKNPTSGNLKVMFNGIYAAQQSQDFLFGRAEVQTSGNPLAHAILRGGQDENGKYHPNYYTDN
LLDTIEIYEKMGLKNPFIVIDTNHDNSGKKFMEQIRIVRQTLVNRDWDDKIRQNVRGFMIESYLEDGRQDKPEVFGKSIT
DPCLGWDKTEALVQEIYEAENKNN

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788953, Length=328, Percent_Identity=39.0243902439024, Blast_Score=210, Evalue=1e-55,
Organism=Escherichia coli, GI1787996, Length=319, Percent_Identity=38.5579937304075, Blast_Score=207, Evalue=7e-55,
Organism=Escherichia coli, GI1786969, Length=319, Percent_Identity=40.4388714733542, Blast_Score=206, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6320240, Length=317, Percent_Identity=36.2776025236593, Blast_Score=181, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6319726, Length=316, Percent_Identity=36.7088607594937, Blast_Score=176, Evalue=4e-45,

Paralogues:

None

Copy number: 2,200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 39221; Mature: 39090

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFKEISPKINIDAIKMLGHLNSEQQEKKLQRDKELEAIIKGEDDRLLLIIGPCSSDNEE
CCCHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHH
AVLEYARRLAKLQEAVKDKIFMVMRVYTAKPRTNGDGYKGLIHEPDADGHTDLINGIKMV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
RDLHYKVITETGLTTADEMLYPENLPMVDDLVSYHAIGARSVENQQHRFVASGIDVPTGL
HHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHHCCHHHCCHHHHHHHCCCCCCCCC
KNPTSGNLKVMFNGIYAAQQSQDFLFGRAEVQTSGNPLAHAILRGGQDENGKYHPNYYTD
CCCCCCCEEEEEEEHHHHCCCCCCEEEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCH
NLLDTIEIYEKMGLKNPFIVIDTNHDNSGKKFMEQIRIVRQTLVNRDWDDKIRQNVRGFM
HHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
IESYLEDGRQDKPEVFGKSITDPCLGWDKTEALVQEIYEAENKNN
HHHHHHCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SFKEISPKINIDAIKMLGHLNSEQQEKKLQRDKELEAIIKGEDDRLLLIIGPCSSDNEE
CCHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHH
AVLEYARRLAKLQEAVKDKIFMVMRVYTAKPRTNGDGYKGLIHEPDADGHTDLINGIKMV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
RDLHYKVITETGLTTADEMLYPENLPMVDDLVSYHAIGARSVENQQHRFVASGIDVPTGL
HHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHHCCHHHCCHHHHHHHCCCCCCCCC
KNPTSGNLKVMFNGIYAAQQSQDFLFGRAEVQTSGNPLAHAILRGGQDENGKYHPNYYTD
CCCCCCCEEEEEEEHHHHCCCCCCEEEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCH
NLLDTIEIYEKMGLKNPFIVIDTNHDNSGKKFMEQIRIVRQTLVNRDWDDKIRQNVRGFM
HHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
IESYLEDGRQDKPEVFGKSITDPCLGWDKTEALVQEIYEAENKNN
HHHHHHCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9422601 [H]