Click here to switch to the map view.

The map label for this gene is mtlR

Identifier: 15672004

GI number: 15672004

Start: 30922

End: 32859

Strand: Direct

Name: mtlR

Synonym: L30901

Alternate gene names: 15672004

Gene position: 30922-32859 (Clockwise)

Preceding gene: 15672003

Following gene: 15672005

Centisome position: 1.31

GC content: 31.89

Gene sequence:

>1938_bases
ATGTTTTTAACAAGTCGTGAGCAAAAATTAATCCAGACATTTTTGAAACGTGGAAAGCTTACGATAGCAGAAATGATGGA
AATTACAGATACAAGTCGCAGAACGCTTTATCGCGATTTGAACAATTTACAAAAGTCTTTACCAGAAAATATCAGTTTGG
AAAATACTGATGAAGGATATTTTTTGAAAGGGGATATCAATCAACTTACTCAAGCTCATGAATTAATAGACTATTCAATA
AGTGAACGTTTGTATGGTGAGTTGCTTTTATTAATTGAAAATAAAGCATCTATCGCTTCTCTAACAGATTATTTTGGAAT
TAGTCAACCGACAGTAACTAGTGATTTGAAGCAAATTGAGCAAGCTCTGTTTGAAAATGAACTAGTACTAATCCGAGATC
GTGGCTTAAAACTTAAAGGGGCAGAAGAAAATATTCGTCCAGTATTTGTGGCAGTAATTTATAATTCAGCAAGCATTCAG
GAACTACTTCTTAATCAACTTTCTAACAATAAAATTTTAAGAATAATAGATTTAAATAAATTTAAGCAAGTTAATGAGGC
TTTTAAACGTATAGATTTACCTGAAAAAATGACTGACAAAGTCAAAGTTTTAATGCAACTTTTTTGCTTAGTTGTTTTGC
TGCGTTTGGATGAGGGGGATTCTGTCAGTAGTGAAACTCTGGGCAGACCAAGTAAGCAAGCCTTAAACTTTGTCAATAAG
TTACTGACAGAGTTGCCAGTAACAAAATTTGTTGTTTCTGAGATCACTTATCTTGCATCAGTTTATGATATTTTATATTT
TGGCTTTGGAAGAGAGCTGCTATTTATGGAAAAATTTGATACCGATTTTTCTTATAAAATTCGCCAACTCATTGATAAAG
TTTCAACAATTCTTGAGATAGAATTTGGGAAAGATGACCGTTTATATGGTTTACTATATGCTCATCTCAAAGAATCAGAG
ATGTTACCAGTCCTCTTTCCTAAAAAAGAAAATGATTTTATCAAAAAGATAAATAAAGATAATCCTGAAATTTATAAAAC
AGTCAAAGAATCATTAAGGGAGGTCTTTGATAAGAATTTTTCAGAAATGGAAATTGCTTTTATAAGTCTTCACTTTGTGG
CGACTCTTGAACGCAGTGACCTAGTTTTACCTTTAAGTGCCGTACTTGTCAGCAGTCGTGGAAGAATTTCTTGCGAATTT
ATCATGAGTAATTTAAGAAAGAATTTTCCCTTCTTAAAAAAGATAGAACTTATTCAAAGTTCAATCCATATCACTCAGGA
AAAATATGACGTCATTTTTACAACAGAGAAAGAGTTAGATTACATCTACATCAATCCAATGCTAGATCAAAAGAATTTGG
AAAATATTCGTCACCAGCTGAGGTTAATTCAACAAAAATCACGAGCACTTACCTCTGATTCAGAAAAAGAAAAGAATTTT
TTAAATCTCAATGACTTATTTTCAATAGGCAATGAAATATTAAAATCTTTTGAAATCCTATCTCTTGAAAATAAGGCAGA
ATTACATGATACTGTAAAACAAATTATTCAGCGAGTAAACCCAGAGGATAGTGGAGAACTCGTTCATTTGGTGGAAGAAA
GATTTAAAGAAACACATCTAGCAATTCCAGAAACAAAAATTGCTCTCTTTCACGCAGTTCATTCATCAATCTCAAGTCCA
ATGTTTAAAATCTTTGACTTAAGTCAACCAATTGAAGGAATAGCAATGGATCATCAGGCTATTCAAATTGGACGAGTTCT
ATTGTTATTAGCGCCTCCAGAAGTTCCAGAGTATGTTTCCTTTTTATTAGGTAAAATCTCAAGTTCAATTATTGAAAACA
AGCTTTATACTAGGATATACGATTCCGGAAATTATGAAATTGTAAGTGAGTTACTAAGAGAGATAATTATCGAAGCTGTT
AAACATTATGATGACTAG

Upstream 100 bases:

>100_bases
ACTCCTGAATACATCAATATGGTGAAACGGATGAACAAATAAAATACTAGCTGTTAATTGGCAGTCTAGTTATGAGTAGA
ATTTTAAAAAAGGAATTTTT

Downstream 100 bases:

>100_bases
GTTTACATAAGTTGTAAACCTAGTAAACCAAGAAAGGTAGTTTTTAAATGGAAATTCAAAAAAGTCTGATTAAAATTAAT
CAAAACTTTTCAAATAAAGA

Product: LysR family transcription regulator

Products: NA

Alternate protein names: Putative phosphotransferase enzyme IIA component; Putative PTS system EIIA component [H]

Number of amino acids: Translated: 645; Mature: 645

Protein sequence:

>645_residues
MFLTSREQKLIQTFLKRGKLTIAEMMEITDTSRRTLYRDLNNLQKSLPENISLENTDEGYFLKGDINQLTQAHELIDYSI
SERLYGELLLLIENKASIASLTDYFGISQPTVTSDLKQIEQALFENELVLIRDRGLKLKGAEENIRPVFVAVIYNSASIQ
ELLLNQLSNNKILRIIDLNKFKQVNEAFKRIDLPEKMTDKVKVLMQLFCLVVLLRLDEGDSVSSETLGRPSKQALNFVNK
LLTELPVTKFVVSEITYLASVYDILYFGFGRELLFMEKFDTDFSYKIRQLIDKVSTILEIEFGKDDRLYGLLYAHLKESE
MLPVLFPKKENDFIKKINKDNPEIYKTVKESLREVFDKNFSEMEIAFISLHFVATLERSDLVLPLSAVLVSSRGRISCEF
IMSNLRKNFPFLKKIELIQSSIHITQEKYDVIFTTEKELDYIYINPMLDQKNLENIRHQLRLIQQKSRALTSDSEKEKNF
LNLNDLFSIGNEILKSFEILSLENKAELHDTVKQIIQRVNPEDSGELVHLVEERFKETHLAIPETKIALFHAVHSSISSP
MFKIFDLSQPIEGIAMDHQAIQIGRVLLLLAPPEVPEYVSFLLGKISSSIIENKLYTRIYDSGNYEIVSELLREIIIEAV
KHYDD

Sequences:

>Translated_645_residues
MFLTSREQKLIQTFLKRGKLTIAEMMEITDTSRRTLYRDLNNLQKSLPENISLENTDEGYFLKGDINQLTQAHELIDYSI
SERLYGELLLLIENKASIASLTDYFGISQPTVTSDLKQIEQALFENELVLIRDRGLKLKGAEENIRPVFVAVIYNSASIQ
ELLLNQLSNNKILRIIDLNKFKQVNEAFKRIDLPEKMTDKVKVLMQLFCLVVLLRLDEGDSVSSETLGRPSKQALNFVNK
LLTELPVTKFVVSEITYLASVYDILYFGFGRELLFMEKFDTDFSYKIRQLIDKVSTILEIEFGKDDRLYGLLYAHLKESE
MLPVLFPKKENDFIKKINKDNPEIYKTVKESLREVFDKNFSEMEIAFISLHFVATLERSDLVLPLSAVLVSSRGRISCEF
IMSNLRKNFPFLKKIELIQSSIHITQEKYDVIFTTEKELDYIYINPMLDQKNLENIRHQLRLIQQKSRALTSDSEKEKNF
LNLNDLFSIGNEILKSFEILSLENKAELHDTVKQIIQRVNPEDSGELVHLVEERFKETHLAIPETKIALFHAVHSSISSP
MFKIFDLSQPIEGIAMDHQAIQIGRVLLLLAPPEVPEYVSFLLGKISSSIIENKLYTRIYDSGNYEIVSELLREIIIEAV
KHYDD
>Mature_645_residues
MFLTSREQKLIQTFLKRGKLTIAEMMEITDTSRRTLYRDLNNLQKSLPENISLENTDEGYFLKGDINQLTQAHELIDYSI
SERLYGELLLLIENKASIASLTDYFGISQPTVTSDLKQIEQALFENELVLIRDRGLKLKGAEENIRPVFVAVIYNSASIQ
ELLLNQLSNNKILRIIDLNKFKQVNEAFKRIDLPEKMTDKVKVLMQLFCLVVLLRLDEGDSVSSETLGRPSKQALNFVNK
LLTELPVTKFVVSEITYLASVYDILYFGFGRELLFMEKFDTDFSYKIRQLIDKVSTILEIEFGKDDRLYGLLYAHLKESE
MLPVLFPKKENDFIKKINKDNPEIYKTVKESLREVFDKNFSEMEIAFISLHFVATLERSDLVLPLSAVLVSSRGRISCEF
IMSNLRKNFPFLKKIELIQSSIHITQEKYDVIFTTEKELDYIYINPMLDQKNLENIRHQLRLIQQKSRALTSDSEKEKNF
LNLNDLFSIGNEILKSFEILSLENKAELHDTVKQIIQRVNPEDSGELVHLVEERFKETHLAIPETKIALFHAVHSSISSP
MFKIFDLSQPIEGIAMDHQAIQIGRVLLLLAPPEVPEYVSFLLGKISSSIIENKLYTRIYDSGNYEIVSELLREIIIEAV
KHYDD

Specific function: Not necessary for mannitol utilization. May be involved in regulation of the mannitol phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS) [H]

COG id: COG3711

COG function: function code K; Transcriptional antiterminator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIA type-2 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013196
- InterPro:   IPR011608
- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR011991 [H]

Pfam domain/function: PF08279 HTH_11; PF00359 PTS_EIIA_2 [H]

EC number: NA

Molecular weight: Translated: 74581; Mature: 74581

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS51094 PTS_EIIA_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLTSREQKLIQTFLKRGKLTIAEMMEITDTSRRTLYRDLNNLQKSLPENISLENTDEGY
CCCCCHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCE
FLKGDINQLTQAHELIDYSISERLYGELLLLIENKASIASLTDYFGISQPTVTSDLKQIE
EEECCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHH
QALFENELVLIRDRGLKLKGAEENIRPVFVAVIYNSASIQELLLNQLSNNKILRIIDLNK
HHHHCCCEEEEECCCCEECCCCCCCCEEEEEEEECCHHHHHHHHHHHCCCCEEEEEECHH
FKQVNEAFKRIDLPEKMTDKVKVLMQLFCLVVLLRLDEGDSVSSETLGRPSKQALNFVNK
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHH
LLTELPVTKFVVSEITYLASVYDILYFGFGRELLFMEKFDTDFSYKIRQLIDKVSTILEI
HHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHCCCCHHHHHHHHHHHHHHHEEE
EFGKDDRLYGLLYAHLKESEMLPVLFPKKENDFIKKINKDNPEIYKTVKESLREVFDKNF
EECCCCCHHHHHHHHHCCCCCCCEECCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHCCCC
SEMEIAFISLHFVATLERSDLVLPLSAVLVSSRGRISCEFIMSNLRKNFPFLKKIELIQS
CHHHHHHHHHHHHHHCCCCCCEEHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHH
SIHITQEKYDVIFTTEKELDYIYINPMLDQKNLENIRHQLRLIQQKSRALTSDSEKEKNF
HHHHHHCCEEEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCC
LNLNDLFSIGNEILKSFEILSLENKAELHDTVKQIIQRVNPEDSGELVHLVEERFKETHL
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHC
AIPETKIALFHAVHSSISSPMFKIFDLSQPIEGIAMDHQAIQIGRVLLLLAPPEVPEYVS
CCCCHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHCCEEEEECCCCCHHHHH
FLLGKISSSIIENKLYTRIYDSGNYEIVSELLREIIIEAVKHYDD
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFLTSREQKLIQTFLKRGKLTIAEMMEITDTSRRTLYRDLNNLQKSLPENISLENTDEGY
CCCCCHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCE
FLKGDINQLTQAHELIDYSISERLYGELLLLIENKASIASLTDYFGISQPTVTSDLKQIE
EEECCHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHH
QALFENELVLIRDRGLKLKGAEENIRPVFVAVIYNSASIQELLLNQLSNNKILRIIDLNK
HHHHCCCEEEEECCCCEECCCCCCCCEEEEEEEECCHHHHHHHHHHHCCCCEEEEEECHH
FKQVNEAFKRIDLPEKMTDKVKVLMQLFCLVVLLRLDEGDSVSSETLGRPSKQALNFVNK
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHH
LLTELPVTKFVVSEITYLASVYDILYFGFGRELLFMEKFDTDFSYKIRQLIDKVSTILEI
HHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHCCCCHHHHHHHHHHHHHHHEEE
EFGKDDRLYGLLYAHLKESEMLPVLFPKKENDFIKKINKDNPEIYKTVKESLREVFDKNF
EECCCCCHHHHHHHHHCCCCCCCEECCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHCCCC
SEMEIAFISLHFVATLERSDLVLPLSAVLVSSRGRISCEFIMSNLRKNFPFLKKIELIQS
CHHHHHHHHHHHHHHCCCCCCEEHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHH
SIHITQEKYDVIFTTEKELDYIYINPMLDQKNLENIRHQLRLIQQKSRALTSDSEKEKNF
HHHHHHCCEEEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCC
LNLNDLFSIGNEILKSFEILSLENKAELHDTVKQIIQRVNPEDSGELVHLVEERFKETHL
CCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHC
AIPETKIALFHAVHSSISSPMFKIFDLSQPIEGIAMDHQAIQIGRVLLLLAPPEVPEYVS
CCCCHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHCCEEEEECCCCCHHHHH
FLLGKISSSIIENKLYTRIYDSGNYEIVSELLREIIIEAVKHYDD
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10878121; 12397186; 1322373 [H]