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The map label for this gene is aroK

Identifier: 15835261

GI number: 15835261

Start: 773219

End: 773773

Strand: Direct

Name: aroK

Synonym: TC0646

Alternate gene names: 15835261

Gene position: 773219-773773 (Clockwise)

Preceding gene: 15835260

Following gene: 15835262

Centisome position: 72.06

GC content: 41.08

Gene sequence:

>555_bases
ATGCCAACATTCGACACCACCAAGCAGATTTTTCTTTGCGGTCTTCCCTCTGTAGGTAAAACCTCTTTTGGGAGACTTTT
AGCTCAGTTTTTATCGCTTCCCTTTTTTGACACGGATCATCTTCTTTCTGCTCGTTTTCATGGGGATTCCCCTAAAGCCA
TTTACCAACGTTTCGGAGAAGAAGGGTTTTGCCAAGAAGAACTCCTCACTTTAATTAACCTTCCTGTTATCCCTAGTGTA
GTTGCATTGGGAGGGAAGACCCTTCTCGATAAACAAATCTATGAACATATTACCCAACGGGAAAACATTCTTTTAGTCTT
ACTCGACCTCCCCTTTGCTACCTTATATCAACGCTTACAAAAAAAACCGCTTCCAGAAAGCCTTAAAAATACCCCTTCAT
TAGAAAATGCTTTGTTCCAGCGCTTAGAAAAACTTCGCCTGCTCACCCCCCATATTTTCTCTTTACAAGCAGCTACCTCT
CTTCATGAGATAGGAGAAGTTTGTCAAAGTTTTTGCTTGCAATTCTTGACTGCACAAGAGATTCCTTATGCATAA

Upstream 100 bases:

>100_bases
GTAGCAGGAGTTCATGCCTCTTCCGGACAAACCCTCCTTTGTAACACACAATGTGTAAATAAGAGTTTTCCTCATTTCGT
GATTGCTGCACAGACACTAC

Downstream 100 bases:

>100_bases
TCAATATGGATCCCTATTTTCTATTACTACCTGGGGAGAATCTCACGGTCCCTCTATCGGAGTCGTTATTGATGGTTGTC
CCGCTGGACTTCCTTTAGCA

Product: shikimate kinase

Products: NA

Alternate protein names: SK

Number of amino acids: Translated: 184; Mature: 183

Protein sequence:

>184_residues
MPTFDTTKQIFLCGLPSVGKTSFGRLLAQFLSLPFFDTDHLLSARFHGDSPKAIYQRFGEEGFCQEELLTLINLPVIPSV
VALGGKTLLDKQIYEHITQRENILLVLLDLPFATLYQRLQKKPLPESLKNTPSLENALFQRLEKLRLLTPHIFSLQAATS
LHEIGEVCQSFCLQFLTAQEIPYA

Sequences:

>Translated_184_residues
MPTFDTTKQIFLCGLPSVGKTSFGRLLAQFLSLPFFDTDHLLSARFHGDSPKAIYQRFGEEGFCQEELLTLINLPVIPSV
VALGGKTLLDKQIYEHITQRENILLVLLDLPFATLYQRLQKKPLPESLKNTPSLENALFQRLEKLRLLTPHIFSLQAATS
LHEIGEVCQSFCLQFLTAQEIPYA
>Mature_183_residues
PTFDTTKQIFLCGLPSVGKTSFGRLLAQFLSLPFFDTDHLLSARFHGDSPKAIYQRFGEEGFCQEELLTLINLPVIPSVV
ALGGKTLLDKQIYEHITQRENILLVLLDLPFATLYQRLQKKPLPESLKNTPSLENALFQRLEKLRLLTPHIFSLQAATSL
HEIGEVCQSFCLQFLTAQEIPYA

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family

Homologues:

None

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): AROK_CHLMU (Q9PK27)

Other databases:

- EMBL:   AE002160
- PIR:   E81679
- RefSeq:   NP_297020.1
- ProteinModelPortal:   Q9PK27
- SMR:   Q9PK27
- GeneID:   1246007
- GenomeReviews:   AE002160_GR
- KEGG:   cmu:TC0646
- TIGR:   TC_0646
- HOGENOM:   HBG414052
- OMA:   TIMHQEA
- ProtClustDB:   PRK00625
- BioCyc:   CMUR243161:TC_0646-MONOMER
- BRENDA:   2.7.1.71
- GO:   GO:0005737
- HAMAP:   MF_00109
- InterPro:   IPR000623
- PRINTS:   PR01100

Pfam domain/function: PF01202 SKI

EC number: =2.7.1.71

Molecular weight: Translated: 20806; Mature: 20674

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: BINDING 39-39 BINDING 85-85

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTFDTTKQIFLCGLPSVGKTSFGRLLAQFLSLPFFDTDHLLSARFHGDSPKAIYQRFGE
CCCCCCCHHHHEECCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHCCC
EGFCQEELLTLINLPVIPSVVALGGKTLLDKQIYEHITQRENILLVLLDLPFATLYQRLQ
CCCCHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHH
KKPLPESLKNTPSLENALFQRLEKLRLLTPHIFSLQAATSLHEIGEVCQSFCLQFLTAQE
CCCCCHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IPYA
CCCC
>Mature Secondary Structure 
PTFDTTKQIFLCGLPSVGKTSFGRLLAQFLSLPFFDTDHLLSARFHGDSPKAIYQRFGE
CCCCCCHHHHEECCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHCCC
EGFCQEELLTLINLPVIPSVVALGGKTLLDKQIYEHITQRENILLVLLDLPFATLYQRLQ
CCCCHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHH
KKPLPESLKNTPSLENALFQRLEKLRLLTPHIFSLQAATSLHEIGEVCQSFCLQFLTAQE
CCCCCHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IPYA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10684935