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Identifier: 15835242

GI number: 15835242

Start: 751365

End: 752951

Strand: Direct

Name: Not Available

Synonym: TC0627

Alternate gene names: 15835242

Gene position: 751365-752951 (Clockwise)

Preceding gene: 15835241

Following gene: 15835243

Centisome position: 70.03

GC content: 41.59

Gene sequence:

>1587_bases
ATGAGTATTGTTCTTGATAAAATCGGCAAAACATTAGGGACACGAGTCTTATTCGATGATGTCTCTGTAGTATTTAACCC
AGGAAATCGTTACGGGTTGACAGGCCCCAACGGAGCTGGAAAATCCACCCTATTGAAGATTATTACTGGAGTAATAGAAC
CTTCTCGGGGAACTATCTCTCTTCCTAAAAAAATTGGGATTCTGCGTCAAAATATTGATAGCTTCAGTGATGTCGTCGTA
TTGGATTGCGTTATCATGGGGAATTCCCGTTTGTGGGAAGCTATGCAACGTCGCGATGCTCTTTATGCAGAGGAGTTCAC
GGATGCTGTAGGGATGGAGCTCGGAGAAATTGAGGAAATTATCGGTGAAGAGGATGGCTATCGCGCAGAGTCTGAAGCCG
AAGAATTGCTTTTAGGTATTGGTATTCCAGAGGAGTTCTTTTCTCAAAAAATGGCTACCATTCCGTTGGATTTGCAATTC
CGCGTCCTCTTGTGTCAAGCTTTGTTTGGACATCCTGAAGCACTGCTTTTGGATGAGCCTACTAACCACTTAGATCTACA
CTCTATCAATTGGCTTGGGAACTTCCTTAAAGACTATAATGGCACGGTCATTGTAGTCAGCCACGACCGGCATTTTTTGA
ATACGATCACAACACATATCGCCGATATCGATTACGATACGATTATTATCTACCCAGGCAATTACGATGCCATGGTTGAA
ATGAAGACTGCTTCTCGAGAGCAAGAAAAGGCAGACATCAAGTCTAAAGAGAAAAAAATTGCTCAATTAAGAGAGTTTGT
AGCTAAATTCGGCGCCGGATCACGAGCAAGCCAAGTGCAGTCTCGCTTAAGAGAAATCAAGAAATTACAACCTCAAGAGC
TGAAAAAATCTAACATTCAGAGACCTTATATTCGGTTCCCTGTATCAGACAAAGCTTCTGGAAAAGTAGTTTTTTCTATA
GAAGGTATCAGCAAAACTTATGATGCTGATCCTTTATTCAACCCCTTCTCTTTAGAGATTTATCAGGGCGATAAGATCGG
TGTGATCGGGAATAATGGTCTGGGGAAAACTACGTTAATGAAGTTATTAGCGGGAGTGGAGCAGCCTTCAGCTGGCCAAA
TCAAGCTAGGTCACAACGTAGCCTTTTCATACTTCCCTCAGAATCACGCTGATGTCTTGAGGGACTGTGGAGAAGAAACT
CTTTTTGAATGGTTGCGTAGACGTAAAACAGGAATTACAGATCAAGAAATTCGAAGTGTTTTAGGGAAGATGCTTTTTGG
AGGAGATGATGCCTTCAAACAAGTCAAAGCTTTATCTGGAGGAGAAACAGCCCGATTGCTTATGGCGGGAATGATGCTGG
AAAATCATAACATGCTTGTTCTTGATGAAGCCAATAACCATTTAGATCTGGAGTCTGTTTCTGCTTTAGCTTGGGCTATT
AATGATTACCCTGGAACGGCTATTTTTGTTTCTCACGATAGAACATTGATAGAAGAGTGTGCAACAAAACTACTGATCTT
TGATAAAGGAGTGATTTCTTTCTTTGATGGGCCAATGTCTGAGTATTTGGCAAGCAAGAAGAAATAA

Upstream 100 bases:

>100_bases
AAAAACAAATCCATGATGAGGCCCATCCTCATAACTTAGAGGATTAATTATACAGGCAAACTTCTTGTACTCTAAGAAGT
TCTTTGTTATCCTCTCAGCC

Downstream 100 bases:

>100_bases
GTCTCTATTAAAACAAGAAATAGAGGGATCACATGGGAACTCAGTTAGTCTTGGGGTCTTCTTCTAAAATAAGGAAAGCT
GTTTTAGAAGCTTTTCGCAT

Product: ABC transporter, ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 528; Mature: 527

Protein sequence:

>528_residues
MSIVLDKIGKTLGTRVLFDDVSVVFNPGNRYGLTGPNGAGKSTLLKIITGVIEPSRGTISLPKKIGILRQNIDSFSDVVV
LDCVIMGNSRLWEAMQRRDALYAEEFTDAVGMELGEIEEIIGEEDGYRAESEAEELLLGIGIPEEFFSQKMATIPLDLQF
RVLLCQALFGHPEALLLDEPTNHLDLHSINWLGNFLKDYNGTVIVVSHDRHFLNTITTHIADIDYDTIIIYPGNYDAMVE
MKTASREQEKADIKSKEKKIAQLREFVAKFGAGSRASQVQSRLREIKKLQPQELKKSNIQRPYIRFPVSDKASGKVVFSI
EGISKTYDADPLFNPFSLEIYQGDKIGVIGNNGLGKTTLMKLLAGVEQPSAGQIKLGHNVAFSYFPQNHADVLRDCGEET
LFEWLRRRKTGITDQEIRSVLGKMLFGGDDAFKQVKALSGGETARLLMAGMMLENHNMLVLDEANNHLDLESVSALAWAI
NDYPGTAIFVSHDRTLIEECATKLLIFDKGVISFFDGPMSEYLASKKK

Sequences:

>Translated_528_residues
MSIVLDKIGKTLGTRVLFDDVSVVFNPGNRYGLTGPNGAGKSTLLKIITGVIEPSRGTISLPKKIGILRQNIDSFSDVVV
LDCVIMGNSRLWEAMQRRDALYAEEFTDAVGMELGEIEEIIGEEDGYRAESEAEELLLGIGIPEEFFSQKMATIPLDLQF
RVLLCQALFGHPEALLLDEPTNHLDLHSINWLGNFLKDYNGTVIVVSHDRHFLNTITTHIADIDYDTIIIYPGNYDAMVE
MKTASREQEKADIKSKEKKIAQLREFVAKFGAGSRASQVQSRLREIKKLQPQELKKSNIQRPYIRFPVSDKASGKVVFSI
EGISKTYDADPLFNPFSLEIYQGDKIGVIGNNGLGKTTLMKLLAGVEQPSAGQIKLGHNVAFSYFPQNHADVLRDCGEET
LFEWLRRRKTGITDQEIRSVLGKMLFGGDDAFKQVKALSGGETARLLMAGMMLENHNMLVLDEANNHLDLESVSALAWAI
NDYPGTAIFVSHDRTLIEECATKLLIFDKGVISFFDGPMSEYLASKKK
>Mature_527_residues
SIVLDKIGKTLGTRVLFDDVSVVFNPGNRYGLTGPNGAGKSTLLKIITGVIEPSRGTISLPKKIGILRQNIDSFSDVVVL
DCVIMGNSRLWEAMQRRDALYAEEFTDAVGMELGEIEEIIGEEDGYRAESEAEELLLGIGIPEEFFSQKMATIPLDLQFR
VLLCQALFGHPEALLLDEPTNHLDLHSINWLGNFLKDYNGTVIVVSHDRHFLNTITTHIADIDYDTIIIYPGNYDAMVEM
KTASREQEKADIKSKEKKIAQLREFVAKFGAGSRASQVQSRLREIKKLQPQELKKSNIQRPYIRFPVSDKASGKVVFSIE
GISKTYDADPLFNPFSLEIYQGDKIGVIGNNGLGKTTLMKLLAGVEQPSAGQIKLGHNVAFSYFPQNHADVLRDCGEETL
FEWLRRRKTGITDQEIRSVLGKMLFGGDDAFKQVKALSGGETARLLMAGMMLENHNMLVLDEANNHLDLESVSALAWAIN
DYPGTAIFVSHDRTLIEECATKLLIFDKGVISFFDGPMSEYLASKKK

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=522, Percent_Identity=31.2260536398467, Blast_Score=239, Evalue=6e-63,
Organism=Homo sapiens, GI27881506, Length=528, Percent_Identity=31.6287878787879, Blast_Score=222, Evalue=6e-58,
Organism=Homo sapiens, GI10947137, Length=528, Percent_Identity=31.6287878787879, Blast_Score=222, Evalue=7e-58,
Organism=Homo sapiens, GI69354671, Length=539, Percent_Identity=30.7977736549165, Blast_Score=212, Evalue=8e-55,
Organism=Homo sapiens, GI10947135, Length=539, Percent_Identity=30.7977736549165, Blast_Score=211, Evalue=1e-54,
Organism=Escherichia coli, GI1787041, Length=529, Percent_Identity=43.289224952741, Blast_Score=442, Evalue=1e-125,
Organism=Escherichia coli, GI2367384, Length=541, Percent_Identity=33.826247689464, Blast_Score=281, Evalue=7e-77,
Organism=Escherichia coli, GI1789751, Length=532, Percent_Identity=32.3308270676692, Blast_Score=273, Evalue=2e-74,
Organism=Escherichia coli, GI1787182, Length=528, Percent_Identity=32.1969696969697, Blast_Score=242, Evalue=5e-65,
Organism=Escherichia coli, GI87081791, Length=211, Percent_Identity=28.9099526066351, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788165, Length=201, Percent_Identity=26.865671641791, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI87081709, Length=231, Percent_Identity=24.2424242424242, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17553372, Length=539, Percent_Identity=34.3228200371057, Blast_Score=256, Evalue=3e-68,
Organism=Caenorhabditis elegans, GI17559834, Length=549, Percent_Identity=28.4153005464481, Blast_Score=220, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI17555318, Length=517, Percent_Identity=29.5938104448743, Blast_Score=214, Evalue=6e-56,
Organism=Saccharomyces cerevisiae, GI6321121, Length=539, Percent_Identity=29.8701298701299, Blast_Score=231, Evalue=2e-61,
Organism=Saccharomyces cerevisiae, GI6320874, Length=530, Percent_Identity=29.0566037735849, Blast_Score=212, Evalue=9e-56,
Organism=Saccharomyces cerevisiae, GI6325030, Length=410, Percent_Identity=25.3658536585366, Blast_Score=114, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6323278, Length=408, Percent_Identity=23.2843137254902, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6324314, Length=206, Percent_Identity=25.7281553398058, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323959, Length=249, Percent_Identity=26.5060240963855, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24666836, Length=532, Percent_Identity=29.8872180451128, Blast_Score=237, Evalue=1e-62,
Organism=Drosophila melanogaster, GI24641342, Length=535, Percent_Identity=30.8411214953271, Blast_Score=222, Evalue=5e-58,
Organism=Drosophila melanogaster, GI24642252, Length=514, Percent_Identity=30.1556420233463, Blast_Score=219, Evalue=4e-57,
Organism=Drosophila melanogaster, GI18859989, Length=514, Percent_Identity=30.1556420233463, Blast_Score=219, Evalue=4e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 58745; Mature: 58614

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIVLDKIGKTLGTRVLFDDVSVVFNPGNRYGLTGPNGAGKSTLLKIITGVIEPSRGTIS
CCEEHHHHHHHHCCEEEEECCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEE
LPKKIGILRQNIDSFSDVVVLDCVIMGNSRLWEAMQRRDALYAEEFTDAVGMELGEIEEI
CHHHHHHHHHHHHHHHHEEEEHEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
IGEEDGYRAESEAEELLLGIGIPEEFFSQKMATIPLDLQFRVLLCQALFGHPEALLLDEP
HCCCCCCCCHHHHHHHEEECCCCHHHHCCCHHCCCCCHHHHHHHHHHHHCCCCEEEEECC
TNHLDLHSINWLGNFLKDYNGTVIVVSHDRHFLNTITTHIADIDYDTIIIYPGNYDAMVE
CCCCCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCCCEEEE
MKTASREQEKADIKSKEKKIAQLREFVAKFGAGSRASQVQSRLREIKKLQPQELKKSNIQ
EHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHCCCC
RPYIRFPVSDKASGKVVFSIEGISKTYDADPLFNPFSLEIYQGDKIGVIGNNGLGKTTLM
CCEEECCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEEEEECCEEEEEECCCCCHHHHH
KLLAGVEQPSAGQIKLGHNVAFSYFPQNHADVLRDCGEETLFEWLRRRKTGITDQEIRSV
HHHHCCCCCCCCEEEECCCEEEEECCCCHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHH
LGKMLFGGDDAFKQVKALSGGETARLLMAGMMLENHNMLVLDEANNHLDLESVSALAWAI
HHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHEE
NDYPGTAIFVSHDRTLIEECATKLLIFDKGVISFFDGPMSEYLASKKK
CCCCCCEEEEECCHHHHHHHHHHEEHCCCCHHHHHCCCHHHHHHCCCC
>Mature Secondary Structure 
SIVLDKIGKTLGTRVLFDDVSVVFNPGNRYGLTGPNGAGKSTLLKIITGVIEPSRGTIS
CEEHHHHHHHHCCEEEEECCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEE
LPKKIGILRQNIDSFSDVVVLDCVIMGNSRLWEAMQRRDALYAEEFTDAVGMELGEIEEI
CHHHHHHHHHHHHHHHHEEEEHEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
IGEEDGYRAESEAEELLLGIGIPEEFFSQKMATIPLDLQFRVLLCQALFGHPEALLLDEP
HCCCCCCCCHHHHHHHEEECCCCHHHHCCCHHCCCCCHHHHHHHHHHHHCCCCEEEEECC
TNHLDLHSINWLGNFLKDYNGTVIVVSHDRHFLNTITTHIADIDYDTIIIYPGNYDAMVE
CCCCCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCCCEEEE
MKTASREQEKADIKSKEKKIAQLREFVAKFGAGSRASQVQSRLREIKKLQPQELKKSNIQ
EHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHCCCC
RPYIRFPVSDKASGKVVFSIEGISKTYDADPLFNPFSLEIYQGDKIGVIGNNGLGKTTLM
CCEEECCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEEEEECCEEEEEECCCCCHHHHH
KLLAGVEQPSAGQIKLGHNVAFSYFPQNHADVLRDCGEETLFEWLRRRKTGITDQEIRSV
HHHHCCCCCCCCEEEECCCEEEEECCCCHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHH
LGKMLFGGDDAFKQVKALSGGETARLLMAGMMLENHNMLVLDEANNHLDLESVSALAWAI
HHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHEE
NDYPGTAIFVSHDRTLIEECATKLLIFDKGVISFFDGPMSEYLASKKK
CCCCCCEEEEECCHHHHHHHHHHEEHCCCCHHHHHCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]