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Identifier: 15835196

GI number: 15835196

Start: 691287

End: 693236

Strand: Reverse

Name: Not Available

Synonym: TC0579

Alternate gene names: 15835196

Gene position: 693236-691287 (Counterclockwise)

Preceding gene: 15835197

Following gene: 15835195

Centisome position: 64.61

GC content: 37.79

Gene sequence:

>1950_bases
ATGCGCATAAACGTGGATAAATACTTATTTATTGGACGTAAAAAGTCTGAATTTTTCTCTGCGTGCCGAGAGCTTGGAGC
TGTCGAATTTTTGGCAAAAAACAAACTCAAGGATTCAGAAAATGTTCGTAGGATTTCTGAAGGGTTAAAAACACTCAATT
TGTTAACGAATAAATATTCGCCATCAGATTTAGTGTTAGTCAAATCTGGATATCTGACAACAGAACAGCTTCTTCAGGAA
ATTTTTGATCTTAATCATGAAATTACAACGATTACAGATTCTTTAAAGGCCTTGAGTAAAGAAATTTTTCGCGTTAAACC
TCTAGGGAATTTCTCCTCTGAGGAAATTCGTGAATTAACGTTGAAAACAGGTTTATCTGTTCGATTTTTCTATAAAAAAC
ATATAGAAGGAGCTCCTTTAGAGGTTGAGGAAGAGAATGTTTTCTATCTAGCAACAGCATACAACTATGATTACTATGTT
GTTATTGGGGTTGTCTCTCTATCCAAAGATATTTTTACAGAAATAGAAGCTCCTCGTTCTGTTGGAGAATTGCGAGAAGA
AGAAGAACATCTTCAAACCCTTTTGCGTAAAAAGAAAGCTCGTGTTTGTGAGTTATATGCTTATCGAGAAGAATTATTAG
AAGCTTTATGTGAGCAATGTAATGAGCAAACTTTACAGCATGCAGAAGCTAGTACAGAAGATTTATTCGATGACAAAGTG
TTTAGTGCTTTGGGTTGGGTTATTGTCGATCGTTTGACTGAAGTAGAAAAGCTTTGTAATAGTTTAGGAGTTTATTTAGA
ACGGGTGCAACCCGATCCAGATGAAGTAATCCCTACATATTTAGAGAACCATGGACTGGGAGCTTTAGGGGAATCTTTGG
TCAATATTTATGATACCCCCGCATCCACAGATAAGGATCCTTCCTTATGGGTCTTTTTATCCTTTTTCGTATTCTTCTCA
ATGATTATTAATGATGCAGGGTACGGTTTAATATTTTTAGCAACTTCATTATTCTTGTCTTTCAAAGCTCGGAAGCAGGT
AAAGCATTCTCTGGCATTAAAACGTTTTCTGAAAATGTTTATGATATTAGGGGGTGGATGCGTTTGCTGGGGTGGGGCTA
CAACATCCTTCTTTGGCGTGTCGGTCAGCTATACAAGTCCTTTTCGGGAATATTCGTTGACGCATTTTCTTGCTATGAAG
AAAGCTGAGTACTACCTGAAGGAGCGCCCCAAAGGCTATAAAGAATTGGTGCATGATTATCCTGTGCTCAAGGATAAAAA
AACTCCTAAAGAGTTTCTTTTGGCTCAAGGGACTAGCAGTGGAGATTCTGTATACAAAGCTGTTGTTTATGATAAATTTA
CAGATAATATTCTAATGGAAATAGCTTTGTTGGTAGGGGTAGTTCATTTGTCTTTAGGGATGTTGCGCTACTGTAGACAA
AGGTATTCTTCTATAGGCTGGGTAGTTTTCATGTGCGGAGCGTATATGTATCTGCCTATCTATTTACAAGCCGTTTCTCT
GATTCATTATGCCTTACACGTTCCTTATGAATTAGGGGGGCAAGTAGGATATTATGTAACATTTATAGGCTTAGGCATAG
CTGTTTTAGGCGGAATTATCCAGAGAGGATTACGAGGCCTGGATGAGGTAACAGCTGTTATTCAAGTGTTTTCAGATGTT
TTGTCCTATTTACGACTGTATGCTCTTAGTTTAGCAGGAGCTATGGTGGGGAACACTGTCATGGTAATGAGCGAAAGATT
TTCCCCCGCAGTAGGGGTCTTGATAATTATCTTTGGGCATACAGTAAATATTGCACTTTCCATTATGGGAGGTGTGATAC
ATGGTCTCCGTCTTAATTTTATAGAATGGTATCACTATAGCTTTGATGGCGGTGGAAGACTTTTGCACCCATTGAAAAGG
GTAATTTGTCAAAAGTCTCAAAATATTTGA

Upstream 100 bases:

>100_bases
TTAAAAAGATAGCTATTTTCTTAAGTGATCGGAGTATTACCGATGTGGGTCAGATGAAAATGGCTAAGAAAAAAATTCAG
CAGCATAAGGAGTAGTCTGC

Downstream 100 bases:

>100_bases
TACAAAGAGTTTTATGTGTGCTTTGTTGAATAAAATAGGAATGATCTAGGTAAAGGAAAGATATGATAGATGTATCAGTA
GTGGGGCCTGTATTAGCTAT

Product: V-type ATP synthase subunit I

Products: ADP; phosphate; H+

Alternate protein names: V-ATPase subunit I

Number of amino acids: Translated: 649; Mature: 649

Protein sequence:

>649_residues
MRINVDKYLFIGRKKSEFFSACRELGAVEFLAKNKLKDSENVRRISEGLKTLNLLTNKYSPSDLVLVKSGYLTTEQLLQE
IFDLNHEITTITDSLKALSKEIFRVKPLGNFSSEEIRELTLKTGLSVRFFYKKHIEGAPLEVEEENVFYLATAYNYDYYV
VIGVVSLSKDIFTEIEAPRSVGELREEEEHLQTLLRKKKARVCELYAYREELLEALCEQCNEQTLQHAEASTEDLFDDKV
FSALGWVIVDRLTEVEKLCNSLGVYLERVQPDPDEVIPTYLENHGLGALGESLVNIYDTPASTDKDPSLWVFLSFFVFFS
MIINDAGYGLIFLATSLFLSFKARKQVKHSLALKRFLKMFMILGGGCVCWGGATTSFFGVSVSYTSPFREYSLTHFLAMK
KAEYYLKERPKGYKELVHDYPVLKDKKTPKEFLLAQGTSSGDSVYKAVVYDKFTDNILMEIALLVGVVHLSLGMLRYCRQ
RYSSIGWVVFMCGAYMYLPIYLQAVSLIHYALHVPYELGGQVGYYVTFIGLGIAVLGGIIQRGLRGLDEVTAVIQVFSDV
LSYLRLYALSLAGAMVGNTVMVMSERFSPAVGVLIIIFGHTVNIALSIMGGVIHGLRLNFIEWYHYSFDGGGRLLHPLKR
VICQKSQNI

Sequences:

>Translated_649_residues
MRINVDKYLFIGRKKSEFFSACRELGAVEFLAKNKLKDSENVRRISEGLKTLNLLTNKYSPSDLVLVKSGYLTTEQLLQE
IFDLNHEITTITDSLKALSKEIFRVKPLGNFSSEEIRELTLKTGLSVRFFYKKHIEGAPLEVEEENVFYLATAYNYDYYV
VIGVVSLSKDIFTEIEAPRSVGELREEEEHLQTLLRKKKARVCELYAYREELLEALCEQCNEQTLQHAEASTEDLFDDKV
FSALGWVIVDRLTEVEKLCNSLGVYLERVQPDPDEVIPTYLENHGLGALGESLVNIYDTPASTDKDPSLWVFLSFFVFFS
MIINDAGYGLIFLATSLFLSFKARKQVKHSLALKRFLKMFMILGGGCVCWGGATTSFFGVSVSYTSPFREYSLTHFLAMK
KAEYYLKERPKGYKELVHDYPVLKDKKTPKEFLLAQGTSSGDSVYKAVVYDKFTDNILMEIALLVGVVHLSLGMLRYCRQ
RYSSIGWVVFMCGAYMYLPIYLQAVSLIHYALHVPYELGGQVGYYVTFIGLGIAVLGGIIQRGLRGLDEVTAVIQVFSDV
LSYLRLYALSLAGAMVGNTVMVMSERFSPAVGVLIIIFGHTVNIALSIMGGVIHGLRLNFIEWYHYSFDGGGRLLHPLKR
VICQKSQNI
>Mature_649_residues
MRINVDKYLFIGRKKSEFFSACRELGAVEFLAKNKLKDSENVRRISEGLKTLNLLTNKYSPSDLVLVKSGYLTTEQLLQE
IFDLNHEITTITDSLKALSKEIFRVKPLGNFSSEEIRELTLKTGLSVRFFYKKHIEGAPLEVEEENVFYLATAYNYDYYV
VIGVVSLSKDIFTEIEAPRSVGELREEEEHLQTLLRKKKARVCELYAYREELLEALCEQCNEQTLQHAEASTEDLFDDKV
FSALGWVIVDRLTEVEKLCNSLGVYLERVQPDPDEVIPTYLENHGLGALGESLVNIYDTPASTDKDPSLWVFLSFFVFFS
MIINDAGYGLIFLATSLFLSFKARKQVKHSLALKRFLKMFMILGGGCVCWGGATTSFFGVSVSYTSPFREYSLTHFLAMK
KAEYYLKERPKGYKELVHDYPVLKDKKTPKEFLLAQGTSSGDSVYKAVVYDKFTDNILMEIALLVGVVHLSLGMLRYCRQ
RYSSIGWVVFMCGAYMYLPIYLQAVSLIHYALHVPYELGGQVGYYVTFIGLGIAVLGGIIQRGLRGLDEVTAVIQVFSDV
LSYLRLYALSLAGAMVGNTVMVMSERFSPAVGVLIIIFGHTVNIALSIMGGVIHGLRLNFIEWYHYSFDGGGRLLHPLKR
VICQKSQNI

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane

COG id: COG1269

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit I

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the V-ATPase 116 kDa subunit family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): VATI_CHLMU (Q9PK88)

Other databases:

- EMBL:   AE002160
- PIR:   C81687
- RefSeq:   NP_296955.1
- GeneID:   1245938
- GenomeReviews:   AE002160_GR
- KEGG:   cmu:TC0579
- TIGR:   TC_0579
- HOGENOM:   HBG414031
- OMA:   YIRLFAV
- ProtClustDB:   PRK05771
- BioCyc:   CMUR243161:TC_0579-MONOMER
- BRENDA:   3.6.3.14
- InterPro:   IPR002490
- PANTHER:   PTHR11629

Pfam domain/function: PF01496 V_ATPase_I

EC number: 3.6.3.14

Molecular weight: Translated: 73436; Mature: 73436

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc4f96c8)-; HASH(0xcf34c20)-; HASH(0xc90bb20)-; HASH(0xc209ba8)-; HASH(0xce18730)-; HASH(0xc671e88)-; HASH(0xcb7a038)-;

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRINVDKYLFIGRKKSEFFSACRELGAVEFLAKNKLKDSENVRRISEGLKTLNLLTNKYS
CCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCC
PSDLVLVKSGYLTTEQLLQEIFDLNHEITTITDSLKALSKEIFRVKPLGNFSSEEIRELT
CCCEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHH
LKTGLSVRFFYKKHIEGAPLEVEEENVFYLATAYNYDYYVVIGVVSLSKDIFTEIEAPRS
HHCCCEEEEEEHHCCCCCCCEEECCCEEEEEEEECCCEEEEEEHHHHHHHHHHHHCCCHH
VGELREEEEHLQTLLRKKKARVCELYAYREELLEALCEQCNEQTLQHAEASTEDLFDDKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
FSALGWVIVDRLTEVEKLCNSLGVYLERVQPDPDEVIPTYLENHGLGALGESLVNIYDTP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCC
ASTDKDPSLWVFLSFFVFFSMIINDAGYGLIFLATSLFLSFKARKQVKHSLALKRFLKMF
CCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MILGGGCVCWGGATTSFFGVSVSYTSPFREYSLTHFLAMKKAEYYLKERPKGYKELVHDY
HHHCCCEEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCC
PVLKDKKTPKEFLLAQGTSSGDSVYKAVVYDKFTDNILMEIALLVGVVHLSLGMLRYCRQ
CCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RYSSIGWVVFMCGAYMYLPIYLQAVSLIHYALHVPYELGGQVGYYVTFIGLGIAVLGGII
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHH
QRGLRGLDEVTAVIQVFSDVLSYLRLYALSLAGAMVGNTVMVMSERFSPAVGVLIIIFGH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHCCCCHHHEEHEEECC
TVNIALSIMGGVIHGLRLNFIEWYHYSFDGGGRLLHPLKRVICQKSQNI
HHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCHHHHHHHHHHHHHCCCH
>Mature Secondary Structure
MRINVDKYLFIGRKKSEFFSACRELGAVEFLAKNKLKDSENVRRISEGLKTLNLLTNKYS
CCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCC
PSDLVLVKSGYLTTEQLLQEIFDLNHEITTITDSLKALSKEIFRVKPLGNFSSEEIRELT
CCCEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHH
LKTGLSVRFFYKKHIEGAPLEVEEENVFYLATAYNYDYYVVIGVVSLSKDIFTEIEAPRS
HHCCCEEEEEEHHCCCCCCCEEECCCEEEEEEEECCCEEEEEEHHHHHHHHHHHHCCCHH
VGELREEEEHLQTLLRKKKARVCELYAYREELLEALCEQCNEQTLQHAEASTEDLFDDKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
FSALGWVIVDRLTEVEKLCNSLGVYLERVQPDPDEVIPTYLENHGLGALGESLVNIYDTP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCC
ASTDKDPSLWVFLSFFVFFSMIINDAGYGLIFLATSLFLSFKARKQVKHSLALKRFLKMF
CCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MILGGGCVCWGGATTSFFGVSVSYTSPFREYSLTHFLAMKKAEYYLKERPKGYKELVHDY
HHHCCCEEEECCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCC
PVLKDKKTPKEFLLAQGTSSGDSVYKAVVYDKFTDNILMEIALLVGVVHLSLGMLRYCRQ
CCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RYSSIGWVVFMCGAYMYLPIYLQAVSLIHYALHVPYELGGQVGYYVTFIGLGIAVLGGII
HHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHH
QRGLRGLDEVTAVIQVFSDVLSYLRLYALSLAGAMVGNTVMVMSERFSPAVGVLIIIFGH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHCCCCHHHEEHEEECC
TVNIALSIMGGVIHGLRLNFIEWYHYSFDGGGRLLHPLKRVICQKSQNI
HHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCHHHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10684935