Click here to switch to the map view.

The map label for this gene is arcR

Identifier: 16120226

GI number: 16120226

Start: 248466

End: 249257

Strand: Reverse

Name: arcR

Synonym: VNG6318G

Alternate gene names: 16120226

Gene position: 249257-248466 (Counterclockwise)

Preceding gene: 16120229

Following gene: 16120225

Centisome position: 68.21

GC content: 60.86

Gene sequence:

>792_bases
ATGGACCCAGAAGCCGCCAACAACGGTGAGCCGCGACGGATAACATCCGTTCTCAACGCGGTCGAAATCATCGACGCGAT
CAAAGAACACCGCGGGATAACGCTCCAAGAGTTGACCACCGAACTCGACCTGACGAAAGCGACGATTCACACGTACATGG
CGACCCTGCGGCAAGTCGGAATCGTCGAACAAGACGGGGACGGAACGTACCAGCTTGGGGATTGGTTCGTTCCGGTCTCG
AACTATGCCCGAAACAGTACTGATCTCTACCGGCTCGGACGCGAAGAGATCGACAAGTTGGCGACCCAGACTCGGCACAC
GGCTCACCTCGTCACGGAGTCAGACGGCCGCCAGATCGTCCTCTACGAATCGATGGGCGAGGAGTCAGTGACCACCGAGT
ATCACCTCCGAATGCGGGAGACGCCACGGAAACTCCACACCAGTGCGGCGGGCAAATCGATACTCGCGTTCCTGCCCGAG
GGCCGTCGGGAGACGTTGATCTCGGAGATCGAGTTCGGCACGGAGTCGTCCACCCCGATCGGCAGCCCTGATGCCCTCCG
CGAGCAACTGGCGACCGTCCGCGATCAGGGATACGCGATCAACGACGAGGAGGAGATCCATGGCATCAGATCGATCGGCG
CACCGATTCGTGGCCGAACGGAGGACGTCGCGGGCGCAGTGAGCGTTACCGCACCGAAGACCCGGCTGCAGAACGCGGAG
TTCGCGGGGGAAGTCCCCGCACTCGTGATGGAAGCCGCAAACATAATCGAGGTGAGGTTAGAGACAGCGTAG

Upstream 100 bases:

>100_bases
CAATAGTGCCATCTCACGATCAAGGACGGTGTTTTTGATAGTTTCAATCCCTGGCCGTGTATTCACGGGAGTATAAACAG
TTGCTATCCATACGAGTAGT

Downstream 100 bases:

>100_bases
CCGCCGCGTGTCATAAACATCGGTATATTTTGGCGACGGCTTTATCAGGCTATATCCAGAATACTCAACTGAATTCCCAT
GAGTAGTGAATCACCGGAGT

Product: transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MDPEAANNGEPRRITSVLNAVEIIDAIKEHRGITLQELTTELDLTKATIHTYMATLRQVGIVEQDGDGTYQLGDWFVPVS
NYARNSTDLYRLGREEIDKLATQTRHTAHLVTESDGRQIVLYESMGEESVTTEYHLRMRETPRKLHTSAAGKSILAFLPE
GRRETLISEIEFGTESSTPIGSPDALREQLATVRDQGYAINDEEEIHGIRSIGAPIRGRTEDVAGAVSVTAPKTRLQNAE
FAGEVPALVMEAANIIEVRLETA

Sequences:

>Translated_263_residues
MDPEAANNGEPRRITSVLNAVEIIDAIKEHRGITLQELTTELDLTKATIHTYMATLRQVGIVEQDGDGTYQLGDWFVPVS
NYARNSTDLYRLGREEIDKLATQTRHTAHLVTESDGRQIVLYESMGEESVTTEYHLRMRETPRKLHTSAAGKSILAFLPE
GRRETLISEIEFGTESSTPIGSPDALREQLATVRDQGYAINDEEEIHGIRSIGAPIRGRTEDVAGAVSVTAPKTRLQNAE
FAGEVPALVMEAANIIEVRLETA
>Mature_263_residues
MDPEAANNGEPRRITSVLNAVEIIDAIKEHRGITLQELTTELDLTKATIHTYMATLRQVGIVEQDGDGTYQLGDWFVPVS
NYARNSTDLYRLGREEIDKLATQTRHTAHLVTESDGRQIVLYESMGEESVTTEYHLRMRETPRKLHTSAAGKSILAFLPE
GRRETLISEIEFGTESSTPIGSPDALREQLATVRDQGYAINDEEEIHGIRSIGAPIRGRTEDVAGAVSVTAPKTRLQNAE
FAGEVPALVMEAANIIEVRLETA

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1786468, Length=231, Percent_Identity=28.5714285714286, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1788131, Length=259, Percent_Identity=26.6409266409266, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI87082359, Length=259, Percent_Identity=25.4826254826255, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788581, Length=233, Percent_Identity=23.6051502145923, Blast_Score=76, Evalue=3e-15,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 29055; Mature: 29055

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPEAANNGEPRRITSVLNAVEIIDAIKEHRGITLQELTTELDLTKATIHTYMATLRQVG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
IVEQDGDGTYQLGDWFVPVSNYARNSTDLYRLGREEIDKLATQTRHTAHLVTESDGRQIV
CEEECCCCCEECCCEEEEHHHHCCCCHHHHHHCHHHHHHHHHHHHHHEEEEEECCCCEEE
LYESMGEESVTTEYHLRMRETPRKLHTSAAGKSILAFLPEGRRETLISEIEFGTESSTPI
EEECCCCCCCCHHHHHHHHHCHHHHHHHHCCCHHEEECCCCHHHHHHHHHHCCCCCCCCC
GSPDALREQLATVRDQGYAINDEEEIHGIRSIGAPIRGRTEDVAGAVSVTAPKTRLQNAE
CCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCHHHCCEEEECCCHHHHCCCC
FAGEVPALVMEAANIIEVRLETA
CCCCHHHHHHHHHHEEEEEEECC
>Mature Secondary Structure
MDPEAANNGEPRRITSVLNAVEIIDAIKEHRGITLQELTTELDLTKATIHTYMATLRQVG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
IVEQDGDGTYQLGDWFVPVSNYARNSTDLYRLGREEIDKLATQTRHTAHLVTESDGRQIV
CEEECCCCCEECCCEEEEHHHHCCCCHHHHHHCHHHHHHHHHHHHHHEEEEEECCCCEEE
LYESMGEESVTTEYHLRMRETPRKLHTSAAGKSILAFLPEGRRETLISEIEFGTESSTPI
EEECCCCCCCCHHHHHHHHHCHHHHHHHHCCCHHEEECCCCHHHHHHHHHHCCCCCCCCC
GSPDALREQLATVRDQGYAINDEEEIHGIRSIGAPIRGRTEDVAGAVSVTAPKTRLQNAE
CCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCHHHCCEEEECCCHHHHCCCC
FAGEVPALVMEAANIIEVRLETA
CCCCHHHHHHHHHHEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]