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The map label for this gene is bdb

Identifier: 16120150

GI number: 16120150

Start: 172222

End: 173682

Strand: Direct

Name: bdb

Synonym: VNG6211G

Alternate gene names: 16120150

Gene position: 172222-173682 (Clockwise)

Preceding gene: 16120149

Following gene: 16120151

Centisome position: 47.13

GC content: 70.5

Gene sequence:

>1461_bases
ATGGAAGCCGCCTGCGACGCCGTCCTGGACGTGATCGGGGGCGCTCACGGGCCGTACTCGGGAGCGAGTTACGACCGCCT
CCGCGACCGGCTTGCGGACACCACGGCGCTGCCCGCGGAGGGACACCCGCTTGAGGACGTGCTCGCGGCCGTTCGGGAGG
ACGTGCTTGCCAACGCGGTGCATCCGAGCGACGAGACCTGTGTCGCGCACCTCCAGTGTCCGCCCATGGTGCCGGCGCTC
GCTGCCGAGGCGCTGCTCACCGCGAGCAACCAGTCGCTTGACTCCTTCGACCAAGCCCCCGCGGCGACTGTCGTCGAGGA
GCGGTTGATCGCCGACCTCACGGCGCTCTACGAGCTTGGCCCGGCCGCCGACGGCGTGGTCACCGGCGGCGGGACGGAGT
CCAACCACCAAGCGCTCCTGCTCGCGCGCGACGACTACGTGGAGACCGTGTTCGGGCAGTCGGTTCGTGAACACGGCCTC
CCGCCGGCGGCCCAAGACCTGCGAATCCTGTGTTCGGCCGACGCGCACTTCACGGCCGCGCAGTCGGCTGCTCTGCTTGG
GTTGGGCGAGGACGCCGTCGTCACGATCCCGACGGACGGCCGCCACCGCATGGACGCCACCGCGCTCAGGGAGACCGTCG
AGCGCCTCAACGACGCCGGCAAACACCCGTTCGCGGTCGTCGGAACCGCGGGCACGACCGACTTCGGGAGTATCGATCCC
CTGTCGGCGGTGGCCGACGTGGCGGCGACCCATGACCTCTGGGTCCACGTGGACGCCGCGTTCGGCGGTGCCCTCGCAGT
CAGCGACCAGCACAGCGAGCGCCTGTCGGGCATCGACCGCGCGGACTCGGTGGCCGTGGACTTCCACAAACTGTTCTTCC
AGCCGATCGCCTGCGGGGCGCTCCTGGTCGCTGACGGGGAATCTTTCGAGCTCATGAGCCGCAACGCGGCGTACCTCAAT
CCGGCGGGCGACGCCGTCCCCAATCTCGTGGCGAAGTCCACGCGCACGACCCGGCGGTTCGACGCGCTGAAGCCGTACGT
CGCGTTCCGGACGCTCGGTCGGGACGGACTCGGGGCGCTCGTGGATCGAACGCTCGCGCTCGCCGACGACGTGGCGGGCC
TGCTGCGTGCTGACCCGGCGTTCGAGCTGGCGTGCGAGCCGACACTGAACGCGGTGACGTTTCGCTACCGGCCGGTCCGC
GAGCACGCCCACTGTGATCCCGGCCCGTGGGCCGATCACGTCACCGAGGCCGCCCGCGAACAGCTGTTCGACGCCGGCAC
CGCCGTGGTCGCGCGAACGACCGTCGACGACCGCGCGCACGTGAAATTCACGCTCATGAACCCGCGCACAACCGTCGCCG
ACATCCAGTCGGTACTCGTTGCGTTCAAAGGACACGCCGCGACGATCGAGGCGGCCGACCGGACCGCTCCGATCACGACC
GCCGCCGGGGGCGACCAATGA

Upstream 100 bases:

>100_bases
CAGCGCCGGCGCGAACGCGTCCACGGACACTGACCCTGTGGCGCTCGCCGACCGGCTGTTCCTCGGGAGCGACGCCGGCA
ACGATGCATACGCCGACGCC

Downstream 100 bases:

>100_bases
CCGGTGTCGGTGCGGTGGCGGACACGCCGGCCGCGCACGCCGAGTCCGCCACCCTGCACGCGTTCCTCAACTGCTACCTC
AGGGAGACCGACGCCGGCGA

Product: L-2,4-diaminobutyrate decarboxylase

Products: NA

Alternate protein names: DABA decarboxylase; DABA-DC [H]

Number of amino acids: Translated: 486; Mature: 486

Protein sequence:

>486_residues
MEAACDAVLDVIGGAHGPYSGASYDRLRDRLADTTALPAEGHPLEDVLAAVREDVLANAVHPSDETCVAHLQCPPMVPAL
AAEALLTASNQSLDSFDQAPAATVVEERLIADLTALYELGPAADGVVTGGGTESNHQALLLARDDYVETVFGQSVREHGL
PPAAQDLRILCSADAHFTAAQSAALLGLGEDAVVTIPTDGRHRMDATALRETVERLNDAGKHPFAVVGTAGTTDFGSIDP
LSAVADVAATHDLWVHVDAAFGGALAVSDQHSERLSGIDRADSVAVDFHKLFFQPIACGALLVADGESFELMSRNAAYLN
PAGDAVPNLVAKSTRTTRRFDALKPYVAFRTLGRDGLGALVDRTLALADDVAGLLRADPAFELACEPTLNAVTFRYRPVR
EHAHCDPGPWADHVTEAAREQLFDAGTAVVARTTVDDRAHVKFTLMNPRTTVADIQSVLVAFKGHAATIEAADRTAPITT
AAGGDQ

Sequences:

>Translated_486_residues
MEAACDAVLDVIGGAHGPYSGASYDRLRDRLADTTALPAEGHPLEDVLAAVREDVLANAVHPSDETCVAHLQCPPMVPAL
AAEALLTASNQSLDSFDQAPAATVVEERLIADLTALYELGPAADGVVTGGGTESNHQALLLARDDYVETVFGQSVREHGL
PPAAQDLRILCSADAHFTAAQSAALLGLGEDAVVTIPTDGRHRMDATALRETVERLNDAGKHPFAVVGTAGTTDFGSIDP
LSAVADVAATHDLWVHVDAAFGGALAVSDQHSERLSGIDRADSVAVDFHKLFFQPIACGALLVADGESFELMSRNAAYLN
PAGDAVPNLVAKSTRTTRRFDALKPYVAFRTLGRDGLGALVDRTLALADDVAGLLRADPAFELACEPTLNAVTFRYRPVR
EHAHCDPGPWADHVTEAAREQLFDAGTAVVARTTVDDRAHVKFTLMNPRTTVADIQSVLVAFKGHAATIEAADRTAPITT
AAGGDQ
>Mature_486_residues
MEAACDAVLDVIGGAHGPYSGASYDRLRDRLADTTALPAEGHPLEDVLAAVREDVLANAVHPSDETCVAHLQCPPMVPAL
AAEALLTASNQSLDSFDQAPAATVVEERLIADLTALYELGPAADGVVTGGGTESNHQALLLARDDYVETVFGQSVREHGL
PPAAQDLRILCSADAHFTAAQSAALLGLGEDAVVTIPTDGRHRMDATALRETVERLNDAGKHPFAVVGTAGTTDFGSIDP
LSAVADVAATHDLWVHVDAAFGGALAVSDQHSERLSGIDRADSVAVDFHKLFFQPIACGALLVADGESFELMSRNAAYLN
PAGDAVPNLVAKSTRTTRRFDALKPYVAFRTLGRDGLGALVDRTLALADDVAGLLRADPAFELACEPTLNAVTFRYRPVR
EHAHCDPGPWADHVTEAAREQLFDAGTAVVARTTVDDRAHVKFTLMNPRTTVADIQSVLVAFKGHAATIEAADRTAPITT
AAGGDQ

Specific function: Unknown

COG id: COG0076

COG function: function code E; Glutamate decarboxylase and related PLP-dependent proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the group II decarboxylase family [H]

Homologues:

Organism=Homo sapiens, GI197383062, Length=431, Percent_Identity=30.8584686774942, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI197276620, Length=392, Percent_Identity=29.5918367346939, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI4503875, Length=392, Percent_Identity=29.5918367346939, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI194294551, Length=392, Percent_Identity=30.8673469387755, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI58331246, Length=435, Percent_Identity=26.4367816091954, Blast_Score=155, Evalue=7e-38,
Organism=Homo sapiens, GI4503281, Length=451, Percent_Identity=26.1640798226164, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI132814448, Length=451, Percent_Identity=26.1640798226164, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI92110055, Length=409, Percent_Identity=25.9168704156479, Blast_Score=112, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17555682, Length=372, Percent_Identity=29.3010752688172, Blast_Score=158, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI71993062, Length=362, Percent_Identity=29.2817679558011, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI71993058, Length=357, Percent_Identity=29.4117647058824, Blast_Score=152, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI17534817, Length=353, Percent_Identity=26.3456090651558, Blast_Score=111, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI17534819, Length=294, Percent_Identity=28.5714285714286, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI133931025, Length=336, Percent_Identity=23.5119047619048, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71981211, Length=250, Percent_Identity=24, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI71981217, Length=250, Percent_Identity=24, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI17136594, Length=386, Percent_Identity=29.5336787564767, Blast_Score=155, Evalue=5e-38,
Organism=Drosophila melanogaster, GI24657193, Length=330, Percent_Identity=28.7878787878788, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24657185, Length=330, Percent_Identity=28.7878787878788, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24657188, Length=330, Percent_Identity=28.7878787878788, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI21356415, Length=440, Percent_Identity=27.2727272727273, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24652373, Length=449, Percent_Identity=27.1714922048998, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI17136190, Length=440, Percent_Identity=25.4545454545455, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24585139, Length=384, Percent_Identity=27.8645833333333, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI221476190, Length=384, Percent_Identity=27.8645833333333, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24585143, Length=384, Percent_Identity=27.8645833333333, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24585135, Length=380, Percent_Identity=26.3157894736842, Blast_Score=105, Evalue=9e-23,
Organism=Drosophila melanogaster, GI28573972, Length=448, Percent_Identity=25, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24586044, Length=378, Percent_Identity=23.5449735449735, Blast_Score=79, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002129
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR021115 [H]

Pfam domain/function: PF00282 Pyridoxal_deC [H]

EC number: =4.1.1.86 [H]

Molecular weight: Translated: 51092; Mature: 51092

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAACDAVLDVIGGAHGPYSGASYDRLRDRLADTTALPAEGHPLEDVLAAVREDVLANAV
CCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCC
HPSDETCVAHLQCPPMVPALAAEALLTASNQSLDSFDQAPAATVVEERLIADLTALYELG
CCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCC
PAADGVVTGGGTESNHQALLLARDDYVETVFGQSVREHGLPPAAQDLRILCSADAHFTAA
CCCCCEEECCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCHHHHEEEECCCCCHHHH
QSAALLGLGEDAVVTIPTDGRHRMDATALRETVERLNDAGKHPFAVVGTAGTTDFGSIDP
HCHHEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCH
LSAVADVAATHDLWVHVDAAFGGALAVSDQHSERLSGIDRADSVAVDFHKLFFQPIACGA
HHHHHHHHHCCEEEEEEECCCCCEEEECCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCE
LLVADGESFELMSRNAAYLNPAGDAVPNLVAKSTRTTRRFDALKPYVAFRTLGRDGLGAL
EEEECCCCHHHHCCCCCEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHH
VDRTLALADDVAGLLRADPAFELACEPTLNAVTFRYRPVREHAHCDPGPWADHVTEAARE
HHHHHHHHHHHHHHHHCCCCCEEECCCCCCEEEEEEEECHHHCCCCCCCCHHHHHHHHHH
QLFDAGTAVVARTTVDDRAHVKFTLMNPRTTVADIQSVLVAFKGHAATIEAADRTAPITT
HHHHCCCEEEEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCEEEECCCCCCCEEE
AAGGDQ
CCCCCC
>Mature Secondary Structure
MEAACDAVLDVIGGAHGPYSGASYDRLRDRLADTTALPAEGHPLEDVLAAVREDVLANAV
CCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCC
HPSDETCVAHLQCPPMVPALAAEALLTASNQSLDSFDQAPAATVVEERLIADLTALYELG
CCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCC
PAADGVVTGGGTESNHQALLLARDDYVETVFGQSVREHGLPPAAQDLRILCSADAHFTAA
CCCCCEEECCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCHHHHEEEECCCCCHHHH
QSAALLGLGEDAVVTIPTDGRHRMDATALRETVERLNDAGKHPFAVVGTAGTTDFGSIDP
HCHHEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCH
LSAVADVAATHDLWVHVDAAFGGALAVSDQHSERLSGIDRADSVAVDFHKLFFQPIACGA
HHHHHHHHHCCEEEEEEECCCCCEEEECCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCE
LLVADGESFELMSRNAAYLNPAGDAVPNLVAKSTRTTRRFDALKPYVAFRTLGRDGLGAL
EEEECCCCHHHHCCCCCEECCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHH
VDRTLALADDVAGLLRADPAFELACEPTLNAVTFRYRPVREHAHCDPGPWADHVTEAARE
HHHHHHHHHHHHHHHHCCCCCEEECCCCCCEEEEEEEECHHHCCCCCCCCHHHHHHHHHH
QLFDAGTAVVARTTVDDRAHVKFTLMNPRTTVADIQSVLVAFKGHAATIEAADRTAPITT
HHHHCCCEEEEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHCCCCEEEECCCCCCCEEE
AAGGDQ
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11274118; 11481432 [H]