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The map label for this gene is gabT

Identifier: 16120149

GI number: 16120149

Start: 170846

End: 172111

Strand: Direct

Name: gabT

Synonym: VNG6210G

Alternate gene names: 16120149

Gene position: 170846-172111 (Clockwise)

Preceding gene: 16120148

Following gene: 16120150

Centisome position: 46.75

GC content: 69.67

Gene sequence:

>1266_bases
ATGGCGGTGACACACGCCGAGGGCATCGAGGTGACCGACGCCGGCGGCACCACCTACCTCGACTGCCTGGCCGGCGCGGG
CACGCTCGCGCTCGGCCACAACCATCCCGCAGTGACCGCGGAGCTGGAGCGATTGCTCGCCGAGGACCGCCCGCTGCACA
CGCTCGACATCACCACACCCGAGAAGGAGGCGTTCGTCGACGCGTTGTTCGACAGTCTGCCGGCCTCGTTCGCGAACACG
GCGAAGGTGCAGTTCTGCTCGCCGGCCGGCACCGACGCCATCGAAGCCGCGCTGAAGCTCACGAAGACCGCCACCGGGAA
CCGGAGCGTGCTCGCGTTCCACGGCGGCTACCACGGCATGACCGCGGGCGCGCTCAGCCTCATGGGCGACATCGACGCCA
AAGAGCCGGTTTCGGGGCTGATGCCGAACGTCCACCACCTCCCGTATCCCGACCAGTACCGCCACCCGTTCGGCCTGCCG
GCGGGCGAACACGAATCCATCCACACGTACATCGAGCACGCCATTAGCAGCCCCGAGCGCGGGTTCACGGAGCCCGCTGC
GGTCGTGCTCGAACTCGTACAGGGAGAAGGAGGGGTCAATCCCGCACCGGACGCCTGGGTGCAGGAGCTCAGGCGCATCA
CTCGGGAACACGACATCCCGCTGGTCGTCGACGAGATCCAGACCGGCCTCGGACGCACCGGTGAGACGTGGTCGTTCGAG
CACGCCGGCATCGAGCCCGATGTCGTCACGTGCTCGAAGGCTGTCGGCGGCGGTCTCCCGCTGGCGGTCGTCCTCTACAA
CGAGGGCCTCGACGTCTGGGAGCCGGGCGCACACGCCGGCACCTTCCGCGGGAACCAGCTCGCGATGGCGGCTGGCCGCG
TCACCATCGAGCACGTTATCGAACAAGACCTCCCCGCCCACGCCGACAAAACGGGGGCGCGGCTCCGCAGCGCGCTCACC
GACCTCGAAGCCGACTTCGACGTCGTCGGCGACGTTCGCGGCCGCGGGCTCATGCTCGGCGTGGAGTTCGTCGCTCCGGA
CGCAGCGGGCGACGAACGCCCGCCGCCGGACGGCGACCTCGCGGCGGCGGTGAAACAGGCGTGCTTCGAGCGCGGACTCA
TCATCGAGACCGGCGGCCGGGATTCCGCGGTCGCGCGGTTCCTGCCGCCGTTGATCGTCTCCAGCCACCAGATCGACGAG
ATCGCGGCCCGGTTCAGCGACGCGGTCACGGCCGTGCTCTCGTCGTCAGCCGAGGTGTCGGCGTGA

Upstream 100 bases:

>100_bases
GGTCATCGTGACTGACCACGACGACACGTCGAACGCTGCCCTCCTCGAAAGCCAACGCCGACGCGAATCGAACGCACGCA
CCTACCCGCGCTCGCTGCCG

Downstream 100 bases:

>100_bases
GCCCGCCGCGCAGCGCCGGCGCGAACGCGTCCACGGACACTGACCCTGTGGCGCTCGCCGACCGGCTGTTCCTCGGGAGC
GACGCCGGCAACGATGCATA

Product: gamma-aminobutyrate aminotransferase

Products: NA

Alternate protein names: Diaminobutyrate transaminase; L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase; DABA aminotransferase; DABA-AT; L-diaminobutyric acid transaminase [H]

Number of amino acids: Translated: 421; Mature: 420

Protein sequence:

>421_residues
MAVTHAEGIEVTDAGGTTYLDCLAGAGTLALGHNHPAVTAELERLLAEDRPLHTLDITTPEKEAFVDALFDSLPASFANT
AKVQFCSPAGTDAIEAALKLTKTATGNRSVLAFHGGYHGMTAGALSLMGDIDAKEPVSGLMPNVHHLPYPDQYRHPFGLP
AGEHESIHTYIEHAISSPERGFTEPAAVVLELVQGEGGVNPAPDAWVQELRRITREHDIPLVVDEIQTGLGRTGETWSFE
HAGIEPDVVTCSKAVGGGLPLAVVLYNEGLDVWEPGAHAGTFRGNQLAMAAGRVTIEHVIEQDLPAHADKTGARLRSALT
DLEADFDVVGDVRGRGLMLGVEFVAPDAAGDERPPPDGDLAAAVKQACFERGLIIETGGRDSAVARFLPPLIVSSHQIDE
IAARFSDAVTAVLSSSAEVSA

Sequences:

>Translated_421_residues
MAVTHAEGIEVTDAGGTTYLDCLAGAGTLALGHNHPAVTAELERLLAEDRPLHTLDITTPEKEAFVDALFDSLPASFANT
AKVQFCSPAGTDAIEAALKLTKTATGNRSVLAFHGGYHGMTAGALSLMGDIDAKEPVSGLMPNVHHLPYPDQYRHPFGLP
AGEHESIHTYIEHAISSPERGFTEPAAVVLELVQGEGGVNPAPDAWVQELRRITREHDIPLVVDEIQTGLGRTGETWSFE
HAGIEPDVVTCSKAVGGGLPLAVVLYNEGLDVWEPGAHAGTFRGNQLAMAAGRVTIEHVIEQDLPAHADKTGARLRSALT
DLEADFDVVGDVRGRGLMLGVEFVAPDAAGDERPPPDGDLAAAVKQACFERGLIIETGGRDSAVARFLPPLIVSSHQIDE
IAARFSDAVTAVLSSSAEVSA
>Mature_420_residues
AVTHAEGIEVTDAGGTTYLDCLAGAGTLALGHNHPAVTAELERLLAEDRPLHTLDITTPEKEAFVDALFDSLPASFANTA
KVQFCSPAGTDAIEAALKLTKTATGNRSVLAFHGGYHGMTAGALSLMGDIDAKEPVSGLMPNVHHLPYPDQYRHPFGLPA
GEHESIHTYIEHAISSPERGFTEPAAVVLELVQGEGGVNPAPDAWVQELRRITREHDIPLVVDEIQTGLGRTGETWSFEH
AGIEPDVVTCSKAVGGGLPLAVVLYNEGLDVWEPGAHAGTFRGNQLAMAAGRVTIEHVIEQDLPAHADKTGARLRSALTD
LEADFDVVGDVRGRGLMLGVEFVAPDAAGDERPPPDGDLAAAVKQACFERGLIIETGGRDSAVARFLPPLIVSSHQIDEI
AARFSDAVTAVLSSSAEVSA

Specific function: Unknown

COG id: COG0160

COG function: function code E; 4-aminobutyrate aminotransferase and related aminotransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI13994255, Length=430, Percent_Identity=27.906976744186, Blast_Score=159, Evalue=6e-39,
Organism=Homo sapiens, GI4557809, Length=410, Percent_Identity=28.2926829268293, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI24119277, Length=426, Percent_Identity=26.2910798122066, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI37574042, Length=434, Percent_Identity=23.963133640553, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI284507298, Length=318, Percent_Identity=29.559748427673, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI226442705, Length=430, Percent_Identity=23.2558139534884, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI226442709, Length=404, Percent_Identity=24.009900990099, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI188536080, Length=450, Percent_Identity=25.7777777777778, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI38679950, Length=450, Percent_Identity=25.7777777777778, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI38679946, Length=450, Percent_Identity=25.7777777777778, Blast_Score=96, Evalue=5e-20,
Organism=Escherichia coli, GI145693181, Length=416, Percent_Identity=29.8076923076923, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI1787560, Length=413, Percent_Identity=32.2033898305085, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI1789016, Length=407, Percent_Identity=32.9238329238329, Blast_Score=179, Evalue=4e-46,
Organism=Escherichia coli, GI1789759, Length=416, Percent_Identity=30.0480769230769, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1788044, Length=418, Percent_Identity=30.3827751196172, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1786991, Length=422, Percent_Identity=27.7251184834123, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786349, Length=361, Percent_Identity=25.4847645429363, Blast_Score=88, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI32564660, Length=427, Percent_Identity=30.2107728337237, Blast_Score=160, Evalue=8e-40,
Organism=Caenorhabditis elegans, GI25144271, Length=426, Percent_Identity=26.7605633802817, Blast_Score=118, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI71992977, Length=427, Percent_Identity=26.2295081967213, Blast_Score=117, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI17541228, Length=429, Percent_Identity=26.3403263403263, Blast_Score=104, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI25144274, Length=312, Percent_Identity=26.6025641025641, Blast_Score=96, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6324432, Length=414, Percent_Identity=29.2270531400966, Blast_Score=163, Evalue=6e-41,
Organism=Saccharomyces cerevisiae, GI6323470, Length=407, Percent_Identity=30.2211302211302, Blast_Score=135, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6321456, Length=372, Percent_Identity=26.6129032258064, Blast_Score=95, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6324386, Length=263, Percent_Identity=25.4752851711027, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28574759, Length=415, Percent_Identity=28.1927710843373, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI161085790, Length=437, Percent_Identity=27.4599542334096, Blast_Score=162, Evalue=5e-40,
Organism=Drosophila melanogaster, GI21357415, Length=412, Percent_Identity=27.1844660194175, Blast_Score=129, Evalue=4e-30,
Organism=Drosophila melanogaster, GI21356575, Length=427, Percent_Identity=25.0585480093677, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI281366494, Length=453, Percent_Identity=24.7240618101545, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24667139, Length=453, Percent_Identity=24.7240618101545, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24667143, Length=453, Percent_Identity=24.7240618101545, Blast_Score=102, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR004637
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.76 [H]

Molecular weight: Translated: 44348; Mature: 44217

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVTHAEGIEVTDAGGTTYLDCLAGAGTLALGHNHPAVTAELERLLAEDRPLHTLDITTP
CCCCCCCCCEEECCCCCHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCCCEEEECCCC
EKEAFVDALFDSLPASFANTAKVQFCSPAGTDAIEAALKLTKTATGNRSVLAFHGGYHGM
HHHHHHHHHHHHHCHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCH
TAGALSLMGDIDAKEPVSGLMPNVHHLPYPDQYRHPFGLPAGEHESIHTYIEHAISSPER
HHHHHHHHHCCCCCCCHHHCCCCCCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHCCCCC
GFTEPAAVVLELVQGEGGVNPAPDAWVQELRRITREHDIPLVVDEIQTGLGRTGETWSFE
CCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEHHHHHHCCCCCCCCCCCC
HAGIEPDVVTCSKAVGGGLPLAVVLYNEGLDVWEPGAHAGTFRGNQLAMAAGRVTIEHVI
CCCCCCCCEEHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEHHCHHHHHHHH
EQDLPAHADKTGARLRSALTDLEADFDVVGDVRGRGLMLGVEFVAPDAAGDERPPPDGDL
HHCCCCCCCHHHHHHHHHHHHHCCCHHHHCCCCCCEEEEEEEEECCCCCCCCCCCCCCHH
AAAVKQACFERGLIIETGGRDSAVARFLPPLIVSSHQIDEIAARFSDAVTAVLSSSAEVS
HHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCC
A
C
>Mature Secondary Structure 
AVTHAEGIEVTDAGGTTYLDCLAGAGTLALGHNHPAVTAELERLLAEDRPLHTLDITTP
CCCCCCCCEEECCCCCHHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCCCCEEEECCCC
EKEAFVDALFDSLPASFANTAKVQFCSPAGTDAIEAALKLTKTATGNRSVLAFHGGYHGM
HHHHHHHHHHHHHCHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCH
TAGALSLMGDIDAKEPVSGLMPNVHHLPYPDQYRHPFGLPAGEHESIHTYIEHAISSPER
HHHHHHHHHCCCCCCCHHHCCCCCCCCCCCHHCCCCCCCCCCCCHHHHHHHHHHHCCCCC
GFTEPAAVVLELVQGEGGVNPAPDAWVQELRRITREHDIPLVVDEIQTGLGRTGETWSFE
CCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCEEHHHHHHCCCCCCCCCCCC
HAGIEPDVVTCSKAVGGGLPLAVVLYNEGLDVWEPGAHAGTFRGNQLAMAAGRVTIEHVI
CCCCCCCCEEHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEHHCHHHHHHHH
EQDLPAHADKTGARLRSALTDLEADFDVVGDVRGRGLMLGVEFVAPDAAGDERPPPDGDL
HHCCCCCCCHHHHHHHHHHHHHCCCHHHHCCCCCCEEEEEEEEECCCCCCCCCCCCCCHH
AAAVKQACFERGLIIETGGRDSAVARFLPPLIVSSHQIDEIAARFSDAVTAVLSSSAEVS
HHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11274118; 11481432 [H]