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The map label for this gene is sucD

Identifier: 15836506

GI number: 15836506

Start: 1115244

End: 1116125

Strand: Direct

Name: sucD

Synonym: CPj0973

Alternate gene names: 15836506

Gene position: 1115244-1116125 (Clockwise)

Preceding gene: 15836505

Following gene: 15836507

Centisome position: 90.92

GC content: 48.41

Gene sequence:

>882_bases
ATGTTCCACTCACTAAGTAAAAATACTCCCATCATCACACAGGGAATTACAGGGAAAGCAGGTTCATTTCATACTGAGCA
GTGCCTCGCCTACGGTACGAATTTCGTAGGGGGTGTGACTCCAGGCAAAGGGGGAACCCTTTGGCTAGACCTGCCAGTCT
ATGATTCTGTACTTGAGGCGAAGCAAGCTACAGGGTGTCGCGCGACCATGATTTTTGTTCCACCACCTTATGCCGCCGAG
GCCATCCTAGAAGCCGAAGAGGCCGGAATCGAACTTATTGTTTGTATTACCGAAGGGATCCCTGTTCGAGATATGCTTGA
AGTGGCTAGAGTTATGGACAACAGTACTTCACAGCTTATCGGCCCGAATTGTCCAGGAATTATCAAGCCTGGAGAATGTA
AAATTGGAATTATGCCAGGATATATCCACCTGCCGGGAAATATTGGAGTGGTCTCTAGATCAGGAACTCTGACATACGAG
GCTGTTTGGCAGCTCACTCAGCTCAAAATCGGCCAGAGTATTTGTGTAGGTATTGGGGGAGACCCCCTCAATGGAACCTC
ATTTATTGATGTCTTGCAGGCGCTGGAGGAGGATCCCTATACAGAACTGATTTTAATGATCGGGGAAATCGGCGGTAGTG
CCGAAGAAGAGGCCGCGGCCTGGATCCAAGCACACTGCACAAAACCCGTGGTTGCTTTTATTGCTGGTGTTACAGCTCCA
AAAGGGAAACGCATGGGGCATGCTGGGGCCATCATCTCTGGAAATTCTGGGGATGCCAAAAGTAAAATACAAGTTCTACG
TGAATCTGGAGTTACTGTAGTTGAGTCTCCGGCCCATATCGGAAAAACTGTAGACGCTGTATTACGGGCAAAAGAACTCT
AA

Upstream 100 bases:

>100_bases
GAAATTGTTCAGCAATCTGGGATTCCTTGCCAATTTGTCTCTTCTATGGAAGAGGGCGCTAGACGCGCTGTAGAACTGAG
TATGTAGATTTAGGAGATAC

Downstream 100 bases:

>100_bases
TGCTTAATCATCTAACCTACAAGTACAGGGTTCGCTTAATCCTTTGGATTGGGAGCTCTCTACTTTAATGAAGATCTTGT
GCTTGGGGACTCATTCTTGC

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha; Vegetative protein 239; VEG239 [H]

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MFHSLSKNTPIITQGITGKAGSFHTEQCLAYGTNFVGGVTPGKGGTLWLDLPVYDSVLEAKQATGCRATMIFVPPPYAAE
AILEAEEAGIELIVCITEGIPVRDMLEVARVMDNSTSQLIGPNCPGIIKPGECKIGIMPGYIHLPGNIGVVSRSGTLTYE
AVWQLTQLKIGQSICVGIGGDPLNGTSFIDVLQALEEDPYTELILMIGEIGGSAEEEAAAWIQAHCTKPVVAFIAGVTAP
KGKRMGHAGAIISGNSGDAKSKIQVLRESGVTVVESPAHIGKTVDAVLRAKEL

Sequences:

>Translated_293_residues
MFHSLSKNTPIITQGITGKAGSFHTEQCLAYGTNFVGGVTPGKGGTLWLDLPVYDSVLEAKQATGCRATMIFVPPPYAAE
AILEAEEAGIELIVCITEGIPVRDMLEVARVMDNSTSQLIGPNCPGIIKPGECKIGIMPGYIHLPGNIGVVSRSGTLTYE
AVWQLTQLKIGQSICVGIGGDPLNGTSFIDVLQALEEDPYTELILMIGEIGGSAEEEAAAWIQAHCTKPVVAFIAGVTAP
KGKRMGHAGAIISGNSGDAKSKIQVLRESGVTVVESPAHIGKTVDAVLRAKEL
>Mature_293_residues
MFHSLSKNTPIITQGITGKAGSFHTEQCLAYGTNFVGGVTPGKGGTLWLDLPVYDSVLEAKQATGCRATMIFVPPPYAAE
AILEAEEAGIELIVCITEGIPVRDMLEVARVMDNSTSQLIGPNCPGIIKPGECKIGIMPGYIHLPGNIGVVSRSGTLTYE
AVWQLTQLKIGQSICVGIGGDPLNGTSFIDVLQALEEDPYTELILMIGEIGGSAEEEAAAWIQAHCTKPVVAFIAGVTAP
KGKRMGHAGAIISGNSGDAKSKIQVLRESGVTVVESPAHIGKTVDAVLRAKEL

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=294, Percent_Identity=59.1836734693878, Blast_Score=295, Evalue=2e-80,
Organism=Homo sapiens, GI38569421, Length=251, Percent_Identity=30.6772908366534, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI38569423, Length=251, Percent_Identity=30.6772908366534, Blast_Score=93, Evalue=2e-19,
Organism=Escherichia coli, GI1786949, Length=285, Percent_Identity=62.1052631578947, Blast_Score=362, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI17550194, Length=292, Percent_Identity=57.5342465753425, Blast_Score=317, Evalue=7e-87,
Organism=Caenorhabditis elegans, GI17553126, Length=289, Percent_Identity=56.7474048442907, Blast_Score=305, Evalue=1e-83,
Organism=Caenorhabditis elegans, GI17557344, Length=257, Percent_Identity=29.1828793774319, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17551266, Length=248, Percent_Identity=30.241935483871, Blast_Score=92, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6324716, Length=289, Percent_Identity=51.9031141868512, Blast_Score=275, Evalue=9e-75,
Organism=Drosophila melanogaster, GI21356559, Length=294, Percent_Identity=54.7619047619048, Blast_Score=313, Evalue=1e-85,
Organism=Drosophila melanogaster, GI28574296, Length=295, Percent_Identity=57.9661016949153, Blast_Score=300, Evalue=9e-82,
Organism=Drosophila melanogaster, GI281363477, Length=251, Percent_Identity=30.6772908366534, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI281363475, Length=251, Percent_Identity=30.6772908366534, Blast_Score=95, Evalue=6e-20,
Organism=Drosophila melanogaster, GI281363473, Length=251, Percent_Identity=30.6772908366534, Blast_Score=95, Evalue=6e-20,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 30708; Mature: 30708

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFHSLSKNTPIITQGITGKAGSFHTEQCLAYGTNFVGGVTPGKGGTLWLDLPVYDSVLEA
CCCCCCCCCCEEEECCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCEEEEECCHHHHHHHH
KQATGCRATMIFVPPPYAAEAILEAEEAGIELIVCITEGIPVRDMLEVARVMDNSTSQLI
HHCCCCEEEEEEECCCHHHHHHHHHHHCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCCC
GPNCPGIIKPGECKIGIMPGYIHLPGNIGVVSRSGTLTYEAVWQLTQLKIGQSICVGIGG
CCCCCCCCCCCCEEEEEECCEEECCCCEEEEECCCCEEHHHHHHHHHHHCCCEEEEECCC
DPLNGTSFIDVLQALEEDPYTELILMIGEIGGSAEEEAAAWIQAHCTKPVVAFIAGVTAP
CCCCCHHHHHHHHHHCCCCHHHHHHHEECCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCC
KGKRMGHAGAIISGNSGDAKSKIQVLRESGVTVVESPAHIGKTVDAVLRAKEL
CCCCCCCCCEEEECCCCCHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFHSLSKNTPIITQGITGKAGSFHTEQCLAYGTNFVGGVTPGKGGTLWLDLPVYDSVLEA
CCCCCCCCCCEEEECCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCEEEEECCHHHHHHHH
KQATGCRATMIFVPPPYAAEAILEAEEAGIELIVCITEGIPVRDMLEVARVMDNSTSQLI
HHCCCCEEEEEEECCCHHHHHHHHHHHCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCCC
GPNCPGIIKPGECKIGIMPGYIHLPGNIGVVSRSGTLTYEAVWQLTQLKIGQSICVGIGG
CCCCCCCCCCCCEEEEEECCEEECCCCEEEEECCCCEEHHHHHHHHHHHCCCEEEEECCC
DPLNGTSFIDVLQALEEDPYTELILMIGEIGGSAEEEAAAWIQAHCTKPVVAFIAGVTAP
CCCCCHHHHHHHHHHCCCCHHHHHHHEECCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCC
KGKRMGHAGAIISGNSGDAKSKIQVLRESGVTVVESPAHIGKTVDAVLRAKEL
CCCCCCCCCEEEECCCCCHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9298659 [H]