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The map label for this gene is folX

Identifier: 15836290

GI number: 15836290

Start: 854054

End: 854458

Strand: Direct

Name: folX

Synonym: CPj0757

Alternate gene names: 15836290

Gene position: 854054-854458 (Clockwise)

Preceding gene: 15836289

Following gene: 15836291

Centisome position: 69.63

GC content: 38.02

Gene sequence:

>405_bases
GTGATTGCTATAGAACGTTATCAGTTAATTATATCCAAGTTTCGTATGTGGTTGTTTTTAGGGTGTTCTGTTGAAGAGCG
TCATTTTAAGCAGCCTGTTCTTATTTCAGTGACTTTTTCTTATAACGAAGTCCCGTCTGCTTGTTTATCCGACAAGCTTT
CAGATGCTTGTTGTTATCTAGAGGTCACCTCTCTTATTGAAGAGATTGCGAATACAAAGCCTTATGCTTTAATAGAGCAC
CTGGCTAACGAGCTATTTGATAGCTTAGTGATATCTTTTGGAGATAAAGCCTCCAAGATAGATCTAGAGGTAGAAAAAGA
ACGGCCACCTGTTCCCAACCTATTAAATCCTATAAAATTTACAATTAGTAAAGAGCTATGTCCGAGCCCCGTTTTGTCTG
CTTAA

Upstream 100 bases:

>100_bases
AAGAAAAAACCGGAACTAGCAAAGTTAAGAGTTTGAAATCCAAATAGTCTTTGAGTAAAAGGTTCGTTTTTTATAGCCTT
GTATAAAAAATATTGCTCTG

Downstream 100 bases:

>100_bases
GTTTAGGATCAAATTTAGGAAATCGTTTTAAAAATCTACAGATTGCTCGTACTTTATTAGGCGAACAAGCTGTTTTAGGT
CTACGTAGTTCGGTAATTCT

Product: dihydroneopterin aldolase

Products: NA

Alternate protein names: DHNA

Number of amino acids: Translated: 134; Mature: 134

Protein sequence:

>134_residues
MIAIERYQLIISKFRMWLFLGCSVEERHFKQPVLISVTFSYNEVPSACLSDKLSDACCYLEVTSLIEEIANTKPYALIEH
LANELFDSLVISFGDKASKIDLEVEKERPPVPNLLNPIKFTISKELCPSPVLSA

Sequences:

>Translated_134_residues
MIAIERYQLIISKFRMWLFLGCSVEERHFKQPVLISVTFSYNEVPSACLSDKLSDACCYLEVTSLIEEIANTKPYALIEH
LANELFDSLVISFGDKASKIDLEVEKERPPVPNLLNPIKFTISKELCPSPVLSA
>Mature_134_residues
MIAIERYQLIISKFRMWLFLGCSVEERHFKQPVLISVTFSYNEVPSACLSDKLSDACCYLEVTSLIEEIANTKPYALIEH
LANELFDSLVISFGDKASKIDLEVEKERPPVPNLLNPIKFTISKELCPSPVLSA

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHNA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FOLB_CHLPN (Q9Z7E9)

Other databases:

- EMBL:   AE001363
- EMBL:   AE002161
- EMBL:   BA000008
- EMBL:   AE009440
- PIR:   C86585
- PIR:   F72039
- RefSeq:   NP_224952.1
- RefSeq:   NP_300814.1
- RefSeq:   NP_445652.1
- RefSeq:   NP_877057.1
- ProteinModelPortal:   Q9Z7E9
- SMR:   Q9Z7E9
- GeneID:   1467464
- GeneID:   894921
- GeneID:   919528
- GeneID:   963604
- GenomeReviews:   AE001363_GR
- GenomeReviews:   AE002161_GR
- GenomeReviews:   AE009440_GR
- GenomeReviews:   BA000008_GR
- KEGG:   cpa:CP1115
- KEGG:   cpn:CPn0757
- KEGG:   cpt:CpB0785
- TIGR:   CP_1115
- HOGENOM:   HBG402778
- OMA:   KERPPVP
- ProtClustDB:   CLSK871488
- BioCyc:   CPNE115711:CP_1115-MONOMER
- BioCyc:   CPNE115713:CPN0757-MONOMER
- BioCyc:   CPNE138677:CPJ0757-MONOMER
- BioCyc:   CPNE182082:CPB0785-MONOMER
- BRENDA:   4.1.2.25
- InterPro:   IPR006156
- InterPro:   IPR006157
- PANTHER:   PTHR20941:SF3
- SMART:   SM00905
- TIGRFAMs:   TIGR00525
- TIGRFAMs:   TIGR00526

Pfam domain/function: PF02152 FolB

EC number: =4.1.2.25

Molecular weight: Translated: 15153; Mature: 15153

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAIERYQLIISKFRMWLFLGCSVEERHFKQPVLISVTFSYNEVPSACLSDKLSDACCYL
CCCHHHHHHHHHHHHHHHHHCCCCCHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHH
EVTSLIEEIANTKPYALIEHLANELFDSLVISFGDKASKIDLEVEKERPPVPNLLNPIKF
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHCHHHH
TISKELCPSPVLSA
HHHHHCCCCCCCCC
>Mature Secondary Structure
MIAIERYQLIISKFRMWLFLGCSVEERHFKQPVLISVTFSYNEVPSACLSDKLSDACCYL
CCCHHHHHHHHHHHHHHHHHCCCCCHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHH
EVTSLIEEIANTKPYALIEHLANELFDSLVISFGDKASKIDLEVEKERPPVPNLLNPIKF
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHCHHHH
TISKELCPSPVLSA
HHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362