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The map label for this gene is frr

Identifier: 15836231

GI number: 15836231

Start: 783503

End: 784045

Strand: Direct

Name: frr

Synonym: CPj0699

Alternate gene names: 15836231

Gene position: 783503-784045 (Clockwise)

Preceding gene: 15836230

Following gene: 15836232

Centisome position: 63.88

GC content: 38.86

Gene sequence:

>543_bases
ATGTCTGTTCTCCAAGACACTGAGAAAAAAATGGCTGCGGCTTTAGATTTTTTTCATAAAGAAGTAAAGTCCTTTAGAAC
AGGAAAAGCTCATCCAGCATTAGTAGAAACTGTTGTAGTCGATGTTTATGGCACTACAATGCGTTTGTCTGATATCGCTT
CGATTTCTGTTGCAGATCTTCGGCAATTGGTTATTTCTCCCTATGACGGGAACAATGCTTCTGCCATTGCAAAAGGAATT
ATTGCAGCGAATTTAAACTTACAGCCTGAAGTCGAAGGGTCTATTATTCGTATTAAGGTCCCTGAGCCTACTGCTGATTA
CCGACAAGAGATGATTAAGCAACTTCGCCGCAAGTGTGAAGAAGCTAAGATCAACGTTAGAAATATCCGCAGAGAAGCTA
ATGACAAGTTGAAAAAAGACTCGGCTCTTACAGAAGATGTTGTCAAAGGTAACGAGAAAAAAATTCAGGAGTTAACTGAC
AAGTTTTGCAAGCAGCTTGATGAGTTAACAAAGCAAAAAGAAGCTGAAATAGCTTCAATATAA

Upstream 100 bases:

>100_bases
TCTCATATTCCAATTCGTGTCTTTAGCTTTTTACAGCACTCTCTAGAAAAGGCTCTATTTGACCCTACGATTGGAACATT
AGTTAGCGAGGATGTAAACC

Downstream 100 bases:

>100_bases
GTATACTTAGGGTTTTTCTTTTCCCTCTGACTTTTTTAGTCATAGAGAGGGAAAAGATTGCTCTAAAGAGAGAAAATTAG
TAACATTTATTCGTCTTGGC

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 180; Mature: 179

Protein sequence:

>180_residues
MSVLQDTEKKMAAALDFFHKEVKSFRTGKAHPALVETVVVDVYGTTMRLSDIASISVADLRQLVISPYDGNNASAIAKGI
IAANLNLQPEVEGSIIRIKVPEPTADYRQEMIKQLRRKCEEAKINVRNIRREANDKLKKDSALTEDVVKGNEKKIQELTD
KFCKQLDELTKQKEAEIASI

Sequences:

>Translated_180_residues
MSVLQDTEKKMAAALDFFHKEVKSFRTGKAHPALVETVVVDVYGTTMRLSDIASISVADLRQLVISPYDGNNASAIAKGI
IAANLNLQPEVEGSIIRIKVPEPTADYRQEMIKQLRRKCEEAKINVRNIRREANDKLKKDSALTEDVVKGNEKKIQELTD
KFCKQLDELTKQKEAEIASI
>Mature_179_residues
SVLQDTEKKMAAALDFFHKEVKSFRTGKAHPALVETVVVDVYGTTMRLSDIASISVADLRQLVISPYDGNNASAIAKGII
AANLNLQPEVEGSIIRIKVPEPTADYRQEMIKQLRRKCEEAKINVRNIRREANDKLKKDSALTEDVVKGNEKKIQELTDK
FCKQLDELTKQKEAEIASI

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI291042689, Length=149, Percent_Identity=31.5436241610738, Blast_Score=71, Evalue=5e-13,
Organism=Homo sapiens, GI20270317, Length=155, Percent_Identity=29.0322580645161, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1786368, Length=178, Percent_Identity=36.5168539325843, Blast_Score=124, Evalue=3e-30,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_CHLPN (Q9Z7K6)

Other databases:

- EMBL:   AE001363
- EMBL:   AE002161
- EMBL:   BA000008
- EMBL:   AE009440
- PIR:   C72045
- PIR:   H86577
- RefSeq:   NP_224895.1
- RefSeq:   NP_300755.1
- RefSeq:   NP_444599.1
- RefSeq:   NP_876998.1
- ProteinModelPortal:   Q9Z7K6
- SMR:   Q9Z7K6
- PHCI-2DPAGE:   Q9Z7K6
- GeneID:   1467405
- GeneID:   895241
- GeneID:   919466
- GeneID:   963669
- GenomeReviews:   AE001363_GR
- GenomeReviews:   AE002161_GR
- GenomeReviews:   AE009440_GR
- GenomeReviews:   BA000008_GR
- KEGG:   cpa:CP0047
- KEGG:   cpn:CPn0699
- KEGG:   cpt:CpB0726
- TIGR:   CP_0047
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- PhylomeDB:   Q9Z7K6
- ProtClustDB:   PRK00083
- BioCyc:   CPNE115711:CP_0047-MONOMER
- BioCyc:   CPNE115713:CPN0699-MONOMER
- BioCyc:   CPNE138677:CPJ0699-MONOMER
- BioCyc:   CPNE182082:CPB0726-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20169; Mature: 20038

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLQDTEKKMAAALDFFHKEVKSFRTGKAHPALVETVVVDVYGTTMRLSDIASISVADL
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
RQLVISPYDGNNASAIAKGIIAANLNLQPEVEGSIIRIKVPEPTADYRQEMIKQLRRKCE
HHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHH
EAKINVRNIRREANDKLKKDSALTEDVVKGNEKKIQELTDKFCKQLDELTKQKEAEIASI
HHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SVLQDTEKKMAAALDFFHKEVKSFRTGKAHPALVETVVVDVYGTTMRLSDIASISVADL
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
RQLVISPYDGNNASAIAKGIIAANLNLQPEVEGSIIRIKVPEPTADYRQEMIKQLRRKCE
HHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHH
EAKINVRNIRREANDKLKKDSALTEDVVKGNEKKIQELTDKFCKQLDELTKQKEAEIASI
HHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362