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The map label for this gene is nqr4

Identifier: 15835962

GI number: 15835962

Start: 474391

End: 475032

Strand: Direct

Name: nqr4

Synonym: CPj0429

Alternate gene names: 15835962

Gene position: 474391-475032 (Clockwise)

Preceding gene: 15835961

Following gene: 15835963

Centisome position: 38.68

GC content: 40.03

Gene sequence:

>642_bases
ATGACAAGTAAAAAGTCCTATAAAAGCTATTTCTTTGATCCTCTATGGAGCAACAACCAAATTCTCATTGCGATTTTGGG
GATTTGCTCGGCTCTGGCAGTGACAACAACAGTACAAACGGCAATTACTATGGGAATTGCTGTCAGCATTGTTACAGGAT
GCTCGTCTTTCTTTGTTTCCTTATTACGTAAGTTCACTCCTGACAGTGTGAGAATGATTACTCAGCTAATTATCATTAGC
TTGTTTGTGATTGTTATCGACCAGTTTTTAAAAGCTTTTTTCTTTGATATTTCCAAAACACTTTCTGTTTTTGTGGGTCT
TATCATCACCAATTGCATCGTGATGGGAAGGTCTGAAAGTCTAGCTAGGCATGTGACTCCTATTCCAGCGTTCTTAGATG
GGTTTGCCTCTGGCTTAGGATACGGCTGGGTCTTACTTGTCATTGGAGTCATCAGAGAACTCTTTGGTTTTGGAACTCTT
ATGGGGTTTCGCATCATCCCTCAATTTGTTTATGCTTCCGAAACCCACCCCGATGGATACCAAAATTTAAGTCTTATGGT
GCTAGCACCGTCGGCTTTTTTCCTACTTGGTATTATGATTTGGCTTGTTAACATTCGAGACTCTAAAAAGAGAAAAAGGT
AG

Upstream 100 bases:

>100_bases
CATGCAACGGTGTCACTGAAGCTTATGTACAATCTCTGGCTTGCTATCGTCAGCTCCTTATAAATTTTTCTAATTTAACC
CATGAAAAGAAAACAGGCGA

Downstream 100 bases:

>100_bases
TTTATGTGGTTAGGTGCGTATACTTGGCTTAATGTCTTTGGTATTCTTCTACAAGCAGCCTTTATTCAGAATATCCTTCT
TGCGAATTTCTTGGGGATGT

Product: Na(+)-translocating NADH-quinone reductase subunit D

Products: NA

Alternate protein names: Na(+)-NQR subunit D; Na(+)-translocating NQR subunit D; NQR complex subunit D; NQR-1 subunit D

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MTSKKSYKSYFFDPLWSNNQILIAILGICSALAVTTTVQTAITMGIAVSIVTGCSSFFVSLLRKFTPDSVRMITQLIIIS
LFVIVIDQFLKAFFFDISKTLSVFVGLIITNCIVMGRSESLARHVTPIPAFLDGFASGLGYGWVLLVIGVIRELFGFGTL
MGFRIIPQFVYASETHPDGYQNLSLMVLAPSAFFLLGIMIWLVNIRDSKKRKR

Sequences:

>Translated_213_residues
MTSKKSYKSYFFDPLWSNNQILIAILGICSALAVTTTVQTAITMGIAVSIVTGCSSFFVSLLRKFTPDSVRMITQLIIIS
LFVIVIDQFLKAFFFDISKTLSVFVGLIITNCIVMGRSESLARHVTPIPAFLDGFASGLGYGWVLLVIGVIRELFGFGTL
MGFRIIPQFVYASETHPDGYQNLSLMVLAPSAFFLLGIMIWLVNIRDSKKRKR
>Mature_212_residues
TSKKSYKSYFFDPLWSNNQILIAILGICSALAVTTTVQTAITMGIAVSIVTGCSSFFVSLLRKFTPDSVRMITQLIIISL
FVIVIDQFLKAFFFDISKTLSVFVGLIITNCIVMGRSESLARHVTPIPAFLDGFASGLGYGWVLLVIGVIRELFGFGTLM
GFRIIPQFVYASETHPDGYQNLSLMVLAPSAFFLLGIMIWLVNIRDSKKRKR

Specific function: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to nqrE are probably involved in the second step, the conversion of ubisemiqui

COG id: COG1347

COG function: function code C; Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nqrDE/rnfAE family

Homologues:

Organism=Escherichia coli, GI1787919, Length=208, Percent_Identity=33.1730769230769, Blast_Score=107, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NQRD_CHLPN (Q9Z8B4)

Other databases:

- EMBL:   AE001363
- EMBL:   AE002161
- EMBL:   BA000008
- EMBL:   AE009440
- PIR:   C86544
- PIR:   G72078
- RefSeq:   NP_224629.1
- RefSeq:   NP_300486.1
- RefSeq:   NP_444873.1
- RefSeq:   NP_876719.1
- GeneID:   1467126
- GeneID:   895128
- GeneID:   919166
- GeneID:   962869
- GenomeReviews:   AE001363_GR
- GenomeReviews:   AE002161_GR
- GenomeReviews:   AE009440_GR
- GenomeReviews:   BA000008_GR
- KEGG:   cpa:CP0324
- KEGG:   cpn:CPn0429
- KEGG:   cpt:CpB0445
- TIGR:   CP_0324
- HOGENOM:   HBG624915
- OMA:   GGWYVPN
- PhylomeDB:   Q9Z8B4
- ProtClustDB:   PRK09292
- BioCyc:   CPNE115711:CP_0324-MONOMER
- BioCyc:   CPNE115713:CPN0429-MONOMER
- BioCyc:   CPNE138677:CPJ0429-MONOMER
- BioCyc:   CPNE182082:CPB0445-MONOMER
- HAMAP:   MF_00428
- InterPro:   IPR003667
- InterPro:   IPR011292
- PIRSF:   PIRSF006102
- TIGRFAMs:   TIGR01939

Pfam domain/function: PF02508 Rnf-Nqr

EC number: NA

Molecular weight: Translated: 23658; Mature: 23526

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc0ba144)-; HASH(0xb3734a0)-; HASH(0xb1962a4)-; HASH(0xbfc8558)-; HASH(0xbd46738)-; HASH(0x404d04dc)-; HASH(0xbfc6224)-;

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSKKSYKSYFFDPLWSNNQILIAILGICSALAVTTTVQTAITMGIAVSIVTGCSSFFVS
CCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLRKFTPDSVRMITQLIIISLFVIVIDQFLKAFFFDISKTLSVFVGLIITNCIVMGRSES
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LARHVTPIPAFLDGFASGLGYGWVLLVIGVIRELFGFGTLMGFRIIPQFVYASETHPDGY
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
QNLSLMVLAPSAFFLLGIMIWLVNIRDSKKRKR
CCCEEEEECCHHHHHHHHHHHHHHCCCHHCCCH
>Mature Secondary Structure 
TSKKSYKSYFFDPLWSNNQILIAILGICSALAVTTTVQTAITMGIAVSIVTGCSSFFVS
CCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLRKFTPDSVRMITQLIIISLFVIVIDQFLKAFFFDISKTLSVFVGLIITNCIVMGRSES
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LARHVTPIPAFLDGFASGLGYGWVLLVIGVIRELFGFGTLMGFRIIPQFVYASETHPDGY
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
QNLSLMVLAPSAFFLLGIMIWLVNIRDSKKRKR
CCCEEEEECCHHHHHHHHHHHHHHCCCHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362