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The map label for this gene is nqr5

Identifier: 15835963

GI number: 15835963

Start: 475036

End: 475806

Strand: Direct

Name: nqr5

Synonym: CPj0430

Alternate gene names: 15835963

Gene position: 475036-475806 (Clockwise)

Preceding gene: 15835962

Following gene: 15835970

Centisome position: 38.73

GC content: 43.71

Gene sequence:

>771_bases
ATGTGGTTAGGTGCGTATACTTGGCTTAATGTCTTTGGTATTCTTCTACAAGCAGCCTTTATTCAGAATATCCTTCTTGC
GAATTTCTTGGGGATGTGTAGTTACCTTGCTTGCTCTACTAGGGTTTCTACAGCCAATGGCTTGGGGATGTCCGTAGCCC
TTGTTCTCACTGTAACAGGGAGCATCAACTGGTTTGTCCATGCTTTCATCACGGGCCCTAAAGCTCTAACTTGGATCTCT
CCATCTTTAGCTTCTGTAAACCTAGGTTTTCTGGAGCTGATTATTTTCATCGTGGTGATTGCGGCATTCACGCAAATCTT
AGAGCTTCTTTTAGAAAAGGTCTCCAGGAATCTATATCTCTCCTTAGGGATCTTCCTTCCCTTGATTGCTGTGAACTGCG
CGATCCTAGGGGGTGTGCTCTTCGGAATCACACGTAGTTATCCTTTTATTCCTATGATGATCTTCTCTTTAGGAGCGGGA
TGTGGGTGGTGGCTCGCTATTGTTATTTTAGCCACTATCAAAGAAAAACTCGCCTACTCTGATATTCCCAAAAACCTCCA
GGGAATGGGGATCTCCTTCATTACAACAGGCCTCATTGCTATGGCTTTTATGAGCTTAACAGGTATTGATATTTCTAAAC
CTTCAGCAAAGATTCAAAGAGCTCCTCTAGAGACTGAAGTTGTTGAAAACACGACCAATCCACTAAAAGAATCTTCGTCC
AAACACCAGCCAAGTATTTCTAAAGCACGAACGCAGCGTCGCTCTCTCTAG

Upstream 100 bases:

>100_bases
TTTAAGTCTTATGGTGCTAGCACCGTCGGCTTTTTTCCTACTTGGTATTATGATTTGGCTTGTTAACATTCGAGACTCTA
AAAAGAGAAAAAGGTAGTTT

Downstream 100 bases:

>100_bases
GAACTTTCCTAGAGTCGAGTTTCTAGTGAACTTTTGTACACAGAGATGCTTCTAAACAATTTCAATTCGAGATATGGAAG
GCGGCTTTTTGCAAGCTGTG

Product: Na(+)-translocating NADH-quinone reductase subunit E

Products: NA

Alternate protein names: Na(+)-NQR subunit E; Na(+)-translocating NQR subunit E; NQR complex subunit E; NQR-1 subunit E

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MWLGAYTWLNVFGILLQAAFIQNILLANFLGMCSYLACSTRVSTANGLGMSVALVLTVTGSINWFVHAFITGPKALTWIS
PSLASVNLGFLELIIFIVVIAAFTQILELLLEKVSRNLYLSLGIFLPLIAVNCAILGGVLFGITRSYPFIPMMIFSLGAG
CGWWLAIVILATIKEKLAYSDIPKNLQGMGISFITTGLIAMAFMSLTGIDISKPSAKIQRAPLETEVVENTTNPLKESSS
KHQPSISKARTQRRSL

Sequences:

>Translated_256_residues
MWLGAYTWLNVFGILLQAAFIQNILLANFLGMCSYLACSTRVSTANGLGMSVALVLTVTGSINWFVHAFITGPKALTWIS
PSLASVNLGFLELIIFIVVIAAFTQILELLLEKVSRNLYLSLGIFLPLIAVNCAILGGVLFGITRSYPFIPMMIFSLGAG
CGWWLAIVILATIKEKLAYSDIPKNLQGMGISFITTGLIAMAFMSLTGIDISKPSAKIQRAPLETEVVENTTNPLKESSS
KHQPSISKARTQRRSL
>Mature_256_residues
MWLGAYTWLNVFGILLQAAFIQNILLANFLGMCSYLACSTRVSTANGLGMSVALVLTVTGSINWFVHAFITGPKALTWIS
PSLASVNLGFLELIIFIVVIAAFTQILELLLEKVSRNLYLSLGIFLPLIAVNCAILGGVLFGITRSYPFIPMMIFSLGAG
CGWWLAIVILATIKEKLAYSDIPKNLQGMGISFITTGLIAMAFMSLTGIDISKPSAKIQRAPLETEVVENTTNPLKESSS
KHQPSISKARTQRRSL

Specific function: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to nqrE are probably involved in the second step, the conversion of ubisemiqui

COG id: COG2209

COG function: function code C; Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrE

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nqrDE/rnfAE family

Homologues:

Organism=Escherichia coli, GI1787914, Length=189, Percent_Identity=36.5079365079365, Blast_Score=124, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NQRE_CHLPN (Q9Z8B3)

Other databases:

- EMBL:   AE001363
- EMBL:   AE002161
- EMBL:   BA000008
- EMBL:   AE009440
- PIR:   D86544
- PIR:   H72078
- RefSeq:   NP_224630.1
- RefSeq:   NP_300487.1
- RefSeq:   NP_444872.1
- RefSeq:   NP_876720.1
- GeneID:   1467127
- GeneID:   894968
- GeneID:   919165
- GeneID:   962875
- GenomeReviews:   AE001363_GR
- GenomeReviews:   AE002161_GR
- GenomeReviews:   AE009440_GR
- GenomeReviews:   BA000008_GR
- KEGG:   cpa:CP0323
- KEGG:   cpn:CPn0430
- KEGG:   cpt:CpB0446
- TIGR:   CP_0323
- HOGENOM:   HBG624915
- OMA:   FLGMCSF
- PhylomeDB:   Q9Z8B3
- ProtClustDB:   PRK01061
- BioCyc:   CPNE115711:CP_0323-MONOMER
- BioCyc:   CPNE115713:CPN0430-MONOMER
- BioCyc:   CPNE138677:CPJ0430-MONOMER
- BioCyc:   CPNE182082:CPB0446-MONOMER
- HAMAP:   MF_00429
- InterPro:   IPR003667
- InterPro:   IPR010967
- PIRSF:   PIRSF006102
- TIGRFAMs:   TIGR01940

Pfam domain/function: PF02508 Rnf-Nqr

EC number: NA

Molecular weight: Translated: 27793; Mature: 27793

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc9d9f14)-; HASH(0xcc0ed10)-; HASH(0xc96799c)-; HASH(0xb6b5fa0)-; HASH(0xbf5f5a0)-; HASH(0xcc0ed04)-;

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWLGAYTWLNVFGILLQAAFIQNILLANFLGMCSYLACSTRVSTANGLGMSVALVLTVTG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHEEECCC
SINWFVHAFITGPKALTWISPSLASVNLGFLELIIFIVVIAAFTQILELLLEKVSRNLYL
CHHHHHHHEECCCCCEEEECCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLGIFLPLIAVNCAILGGVLFGITRSYPFIPMMIFSLGAGCGWWLAIVILATIKEKLAYS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
DIPKNLQGMGISFITTGLIAMAFMSLTGIDISKPSAKIQRAPLETEVVENTTNPLKESSS
HCCCHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHCCCCHHHHCCC
KHQPSISKARTQRRSL
CCCCCHHHHHHHHCCH
>Mature Secondary Structure
MWLGAYTWLNVFGILLQAAFIQNILLANFLGMCSYLACSTRVSTANGLGMSVALVLTVTG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHEEECCC
SINWFVHAFITGPKALTWISPSLASVNLGFLELIIFIVVIAAFTQILELLLEKVSRNLYL
CHHHHHHHEECCCCCEEEECCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLGIFLPLIAVNCAILGGVLFGITRSYPFIPMMIFSLGAGCGWWLAIVILATIKEKLAYS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
DIPKNLQGMGISFITTGLIAMAFMSLTGIDISKPSAKIQRAPLETEVVENTTNPLKESSS
HCCCHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHCCCCHHHHCCC
KHQPSISKARTQRRSL
CCCCCHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362