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The map label for this gene is trxB

Identifier: 15835849

GI number: 15835849

Start: 354972

End: 355907

Strand: Reverse

Name: trxB

Synonym: CPj0314

Alternate gene names: 15835849

Gene position: 355907-354972 (Counterclockwise)

Preceding gene: 15835856

Following gene: 15835846

Centisome position: 29.02

GC content: 41.56

Gene sequence:

>936_bases
ATGATTCATTCCCGGTTAATTATTATTGGTTCAGGTCCATCTGGATATACAGCGGCAATTTATGCATCAAGAGCGCTTTT
GCATCCTCTTTTATTTGAGGGGTTTTTCTCTGGGATCTCTGGTGGCCAGCTTATGACTACAACAGAAGTTGAGAATTTTC
CAGGGTTTCCTGAAGGGATTCTTGGGCCAAAACTTATGAATAATATGAAGGAGCAGGCTGTGCGGTTTGGGACCAAGACA
CTAGCTCAAGATATTATTTCCGTAGATTTTTCTGTTCGCCCTTTTATTTTGAAATCAAAAGAAGAAACCTATTCTTGTGA
TGCCTGTATCATAGCTACAGGAGCTTCTGCTAAACGTTTAGAAATTCCTGGAGCAGGAAACGATGAATTTTGGCAAAAAG
GAGTGACTGCTTGTGCCGTTTGCGATGGGGCTTCTCCTATTTTTAAAAATAAAGATCTTTATGTGATTGGGGGAGGGGAT
TCTGCTTTAGAAGAAGCTCTTTACCTGACTCGTTATGGAAGCCACGTATATGTAGTTCATCGTAGAGATAAACTGCGGGC
TTCTAAAGCTATGGAAGCTCGGGCGCAAAACAATGAAAAAATTACATTTTTATGGAATAGCGAGATTGTAAAAATTTCTG
GAGATAGCATTGTCCGTTCCGTAGATATTAAGAATGTTCAGACTCAAGAAATTACAACTAGAGAAGCTGCGGGGGTGTTC
TTTGCTATAGGCCATAAGCCAAATACGGATTTTCTCGGAGGACAGCTGACGTTAGATGAGTCGGGCTATATTGTGACTGA
GAAAGGAACGTCCAAGACTTCTGTCCCTGGAGTATTTGCTGCTGGAGATGTTCAGGATAAGTACTATCGTCAGGCGGTTA
CTTCTGCAGGAAGTGGTTGTATAGCAGCACTAGATGCTGAAAGATTCTTAGGCTAA

Upstream 100 bases:

>100_bases
GCTAAGTGTTGTTTATTAGATAGGCTAGAATTAAGTGTCTTTTTTCTAGTAGATCAAGAACAGTGTTCTCAATTTCTAAA
GTTAGATAAGGAAATTATAA

Downstream 100 bases:

>100_bases
TGCGATTGCAGTTGCTGTGGCATACTCTTTGCAGTGGCTTATAGAGAGAATGACTTTAGAAATTCCAATTTTTGCATAGA
CATGCGAAGGGAGGAGAACT

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MIHSRLIIIGSGPSGYTAAIYASRALLHPLLFEGFFSGISGGQLMTTTEVENFPGFPEGILGPKLMNNMKEQAVRFGTKT
LAQDIISVDFSVRPFILKSKEETYSCDACIIATGASAKRLEIPGAGNDEFWQKGVTACAVCDGASPIFKNKDLYVIGGGD
SALEEALYLTRYGSHVYVVHRRDKLRASKAMEARAQNNEKITFLWNSEIVKISGDSIVRSVDIKNVQTQEITTREAAGVF
FAIGHKPNTDFLGGQLTLDESGYIVTEKGTSKTSVPGVFAAGDVQDKYYRQAVTSAGSGCIAALDAERFLG

Sequences:

>Translated_311_residues
MIHSRLIIIGSGPSGYTAAIYASRALLHPLLFEGFFSGISGGQLMTTTEVENFPGFPEGILGPKLMNNMKEQAVRFGTKT
LAQDIISVDFSVRPFILKSKEETYSCDACIIATGASAKRLEIPGAGNDEFWQKGVTACAVCDGASPIFKNKDLYVIGGGD
SALEEALYLTRYGSHVYVVHRRDKLRASKAMEARAQNNEKITFLWNSEIVKISGDSIVRSVDIKNVQTQEITTREAAGVF
FAIGHKPNTDFLGGQLTLDESGYIVTEKGTSKTSVPGVFAAGDVQDKYYRQAVTSAGSGCIAALDAERFLG
>Mature_311_residues
MIHSRLIIIGSGPSGYTAAIYASRALLHPLLFEGFFSGISGGQLMTTTEVENFPGFPEGILGPKLMNNMKEQAVRFGTKT
LAQDIISVDFSVRPFILKSKEETYSCDACIIATGASAKRLEIPGAGNDEFWQKGVTACAVCDGASPIFKNKDLYVIGGGD
SALEEALYLTRYGSHVYVVHRRDKLRASKAMEARAQNNEKITFLWNSEIVKISGDSIVRSVDIKNVQTQEITTREAAGVF
FAIGHKPNTDFLGGQLTLDESGYIVTEKGTSKTSVPGVFAAGDVQDKYYRQAVTSAGSGCIAALDAERFLG

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family

Homologues:

Organism=Escherichia coli, GI1787114, Length=317, Percent_Identity=48.8958990536278, Blast_Score=287, Evalue=5e-79,
Organism=Escherichia coli, GI87081763, Length=318, Percent_Identity=31.7610062893082, Blast_Score=121, Evalue=8e-29,
Organism=Saccharomyces cerevisiae, GI6320560, Length=317, Percent_Identity=54.2586750788643, Blast_Score=354, Evalue=8e-99,
Organism=Saccharomyces cerevisiae, GI6321898, Length=317, Percent_Identity=52.9968454258675, Blast_Score=336, Evalue=4e-93,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRXB_CHLPN (Q9Z8M4)

Other databases:

- EMBL:   AE001363
- EMBL:   AE002161
- EMBL:   BA000008
- EMBL:   AE009440
- PIR:   B86530
- PIR:   C72093
- RefSeq:   NP_224519.1
- RefSeq:   NP_300373.1
- RefSeq:   NP_444992.1
- RefSeq:   NP_876599.1
- ProteinModelPortal:   Q9Z8M4
- PHCI-2DPAGE:   Q9Z8M4
- GeneID:   1467006
- GeneID:   894975
- GeneID:   919090
- GeneID:   963713
- GenomeReviews:   AE001363_GR
- GenomeReviews:   AE002161_GR
- GenomeReviews:   AE009440_GR
- GenomeReviews:   BA000008_GR
- KEGG:   cpa:CP0444
- KEGG:   cpn:CPn0314
- KEGG:   cpt:CpB0322
- TIGR:   CP_0444
- HOGENOM:   HBG669726
- OMA:   ACEEATY
- PhylomeDB:   Q9Z8M4
- ProtClustDB:   CLSK871182
- BioCyc:   CPNE115711:CP_0444-MONOMER
- BioCyc:   CPNE115713:CPN0314-MONOMER
- BioCyc:   CPNE138677:CPJ0314-MONOMER
- BioCyc:   CPNE182082:CPB0322-MONOMER
- BRENDA:   1.8.1.9
- GO:   GO:0005737
- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982
- PRINTS:   PR00368
- PRINTS:   PR00469
- TIGRFAMs:   TIGR01292

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2

EC number: =1.8.1.9

Molecular weight: Translated: 33559; Mature: 33559

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHSRLIIIGSGPSGYTAAIYASRALLHPLLFEGFFSGISGGQLMTTTEVENFPGFPEGI
CCCCEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCC
LGPKLMNNMKEQAVRFGTKTLAQDIISVDFSVRPFILKSKEETYSCDACIIATGASAKRL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCEEEEEECCCCEEE
EIPGAGNDEFWQKGVTACAVCDGASPIFKNKDLYVIGGGDSALEEALYLTRYGSHVYVVH
ECCCCCCHHHHHCCCCEEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHEECCCEEEEEE
RRDKLRASKAMEARAQNNEKITFLWNSEIVKISGDSIVRSVDIKNVQTQEITTREAAGVF
CCCHHHHHHHHHHHHCCCCEEEEEECCEEEEECCCCEEEEEECCCCCHHHHHHHHHCCEE
FAIGHKPNTDFLGGQLTLDESGYIVTEKGTSKTSVPGVFAAGDVQDKYYRQAVTSAGSGC
EEECCCCCCCCCCCEEEECCCCEEEECCCCCCCCCCCEEEECCCHHHHHHHHHHCCCCCE
IAALDAERFLG
EEEECHHHHCC
>Mature Secondary Structure
MIHSRLIIIGSGPSGYTAAIYASRALLHPLLFEGFFSGISGGQLMTTTEVENFPGFPEGI
CCCCEEEEEECCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCC
LGPKLMNNMKEQAVRFGTKTLAQDIISVDFSVRPFILKSKEETYSCDACIIATGASAKRL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCEEEEEECCCCEEE
EIPGAGNDEFWQKGVTACAVCDGASPIFKNKDLYVIGGGDSALEEALYLTRYGSHVYVVH
ECCCCCCHHHHHCCCCEEEEECCCCCCCCCCCEEEEECCCHHHHHHHHHEECCCEEEEEE
RRDKLRASKAMEARAQNNEKITFLWNSEIVKISGDSIVRSVDIKNVQTQEITTREAAGVF
CCCHHHHHHHHHHHHCCCCEEEEEECCEEEEECCCCEEEEEECCCCCHHHHHHHHHCCEE
FAIGHKPNTDFLGGQLTLDESGYIVTEKGTSKTSVPGVFAAGDVQDKYYRQAVTSAGSGC
EEECCCCCCCCCCCEEEECCCCEEEECCCCCCCCCCCEEEECCCHHHHHHHHHHCCCCCE
IAALDAERFLG
EEEECHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362